Man

Rodrigo Luis Castillo Peñaloza

Profesor Asistente

University of Chile

Santiago, Chile

Líneas de Investigación


Cardiovascular Pathophysiology Oxidative stress markers Intermittent hypobaric hypoxia Clinical Trials

Educación

  •  Pharmacology, UNIVERSIDAD DE CHILE. Chile, 2011
  •  Medical Doctor, UNIVERSIDAD DE CHILE. Chile, 2006
  •  Fellowship Internal Medicine, Ongoing. Chile, 2019

Experiencia Académica

  •   Assitant Professor Full Time

    UNIVERSIDAD DE CHILE

    Medicine

    Santiago, Chile

    2012 - 2017

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2018 - A la fecha

Experiencia Profesional

  •   Emergency Medical Doctor Part Time

    Centro de Referencia de Salud

    Santiago, Chile

    2008 - 2012

  •   Emergency Medical Doctor Part Time

    Hospital El Carmen de Maipú

    Santiago, Chile

    2014 - A la fecha

  •   Medico Residente Unidad de Paciente Crítico Part Time

    Hospital del Salvador

    Santaigo, Chile

    2019 - A la fecha

Formación de Capital Humano


Liza Mardones Lobos. Undergraduate Doctor in Veterinary Medicine. University of Chile, December, 2013
Research Unit for Medical Students, Since 2012 (Unidades de Investigación y Ayudantes Alumnos), Facultad de Medicina, Universidad de Chile.
Short Stay tutoring for International Federation of Medical Students (IFMSA)

Miguel Aguilar, MD
Master Thesis of Pathophysiology
2016 - 2018
Title: "Hipoxia hipobárica intermitente: efectos agudos y crónicos en la función, estructura y estrés oxidativo cardiovascular"

Jorge Rodriguez-Borgues., Physiotherapist
Master Thesis of Pathophysiology
2016 - 2018
Title: "Marcadores de estrés oxidativo, capacidad antioxidante y estructura pulmonar en ratas expuestas a hipoxia intermitente"


Premios y Distinciones

  •   Prevention of arrhythmias Merk Award

    SOCIEDAD CHILENA DE CARDIOLOGIA

    Chile, 2010

    Congress of Chilean Society of Cardiology, Santiago.

  •   Jorge Mardones Restat Award

    SOCIEDAD DE FARMACOLOGIA DE CHILE

    Chile, 2009

    The best work of PhD student

  •   III Premio Investigación Científica Universitaria

    Santander Universia

    Chile, 2015

    "Cardioprotección con ácidos grasos omega 3 en patologías cardiovasculares en modelos animales y humanos: del Infarto Agudo al Miocardio a la Hipoxia Hipobárica Intermitente", con la que resultó ganador en la categoría Investigador Joven de la Tercera Edición del Premio a la Investigación Científica Universitaria (PIC) entregado por Universia.


 

Article (27)

Antenatal melatonin modulates an enhanced antioxidant/pro-oxidant ratio in pulmonary hypertensive newborn sheep.
Chronic hypobaric hypoxia diminishes the expression of base excision repair OGG1 enzymes in spermatozoa
Mechanisms of Cardiovascular Protection Associated with Intermittent Hypobaric Hypoxia Exposure in a Rat Model: Role of Oxidative Stress
Quercetin Prevents Diastolic Dysfunction Induced by a High-Cholesterol Diet: Role of Oxidative Stress and Bioenergetics in Hyperglycemic Rats
Effects of cryopreservation on mitochondria of fish spermatozoa
Polyunsaturated fatty acid induces cardioprotection against ischemia-reperfusion through the inhibition of NF-kappaB and induction of Nrf2
Molecular mechanisms of gastrointestinal protection by quercetin against indomethacin-induced damage: role of NF-kappa B and Nrf2
3,4-Dihydroxyphenylacetic acid, a microbiota-derived metabolite of quercetin, protects against pancreatic β-cells dysfunction induced by high cholesterol.
Molecular aspects of breast cancer resistance to drugs (Review)
Omega 3 supplementation and intermittent hypobaric hypoxia induce cardioprotection enhancing antioxidant mechanisms in adult rats.
Pathophysiological Approaches of Acute Respiratory Distress Syndrome: Novel Bases for Study of Lung Injury
Pharmacological approaches in either intermittent or permanent hypoxia: A tale of two exposures.
Protective effects of polyunsatutared fatty acids supplementation against testicular damage induced by intermittent hypobaric hypoxia in rats
Transfusion-Related Acute Lung Injured (TRALI): Current Concepts
Cellular mechanisms against ischemia reperfusion injury induced by the use of anesthetic pharmacological agents.
Effects of Chronic Intermittent Hypoxia and Polyunsaturated Fatty Acids on Infarct Size and Oxidative Stress Markers in Cardiac Ischemia Reperfusion
Omega 3 chronic supplementation attenuates myocardial ischaemia-reperfusion injury through reinforcement of antioxidant defense system in rats
A Randomized Controlled Trial to Prevent Post-Operative Atrial Fibrillation by Antioxidant Reinforcement
Relationship between severity of adult community-acquired pneumonia and impairment of the antioxidant defense system
Effect of Carvedilol and Nebivolol on Oxidative Stress-related Parameters and Endothelial Function in Patients with Essential Hypertension
Antioxidant Therapy Reduces Oxidative and Inflammatory Tissue Damage in Patients Subjected to Cardiac Surgery with Extracorporeal Circulation
Oxidative stress as a novel target in pediatric sepsis management
Use of vitamins C and E as a prophylactic therapy to prevent postoperative atrial fibrillation
Nueva estrategia de preacondicionamiento no hipóxico que atenúa el efecto de la Isquemia-Reperfusión en pacientes sometidos a cirugía cardíaca con circulación extracorpórea
Non-hypoxic preconditioning of myocardium against postoperative atrial fibrillation: Mechanism based on enhancement of the antioxidant defense system
Chronic ethanol exposure does not impair urinary acidification even under stressful conditions
Diminution of tissue lipid peroxidation in rats is related to the in vitro antioxidant capacity of wine

BookReview (2)

Cardiac Pharmacological Preconditioning Associated with Omega 3 Supplementation: Potential Clinical Applications
No Ventilatory Complications of ARDS: Difficult Weaning and Intensive Care Unit-Acquired Weakness

Editorial (1)

Acute respiratory failure: Pathophysiological basis from a multidisciplinary clinical approach

Proyecto (2)

Molecular basis of a novel theraphy for cardioprotection through the administration of polyunsaturated fatty acids and vitamins C and E.
“CARDIOPROTECCIÓN CON ACIDOS GRASOS OMEGA 3 EN PATOLOGÍAS CARDIOVASCULARES EN MODELOS ANIMALES Y HUMANOS: Del Infarto Agudo al Miocardio a la Hipoxia Hipobárica Intermitente.”

Review (5)

Dexmedetomidine Improves Cardiovascular and Ventilatory Outcomes in Critically Ill Patients: Basic and Clinical Approaches
Pharmacological models and approaches for pathophysiological conditions associated with hypoxia and oxidative stress
Cellular mechanisms against ischemia reperfusion injury induced by the use of anesthetic pharmacological agents
Cardioprotection against ischaemia/reperfusion by vitamins C and E plus n-3 fatty acids: molecular mechanisms and potential clinical applications
Prevention of atrial fibrillation following cardiac surgery: Basis for a novel therapeutic strategy based on non-hypoxic myocardial preconditioning
32
Rodrigo Castillo

Profesor Asistente

Medicina Interna Oriente

University of Chile

Santiago, Chile

10
Ramón Rodrigo

PROFESOR TITULAR

INSTITUTO DE CIENCIAS BIOMÉDICAS

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA

Santiago, Chile

7
Jorge Farias

Associate Professor A

Chemical Engineering

Universidad de La Frontera

Temuco, Chile

5
RODRIGO CARRASCO

CLINICAL FELLOW

CARDIOLOGIA

UNIVERSITY OF TORONTO

Toronto, Canada

3
Elías Figueroa

Associate Professor.

Department of Biological and Chemical Sciences

Catholic University of Temuco

Temuco, Chile

2
Rubén Aguayo

Director de Departamento Medicina Interna Occidente

Departamento de Medicina Interna Occidente

Universidad de Chile

Santiago, Chile

2
Juan Prieto

Profesor Titular

Programa de Farmacología Molecular y Clínica

Universidad de Chile

Santiago, Chile

2
Emilio HERRERA

Associate Professor

Faculty of Medicine, ICBM

Universidad de Chile

Santiago, Chile

1
Gonzalo Cruz

UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

1
Gloria Calaf

Directora Laboratorio Biología del cáncer

Universidad de Tarapacá

Arica, Chile

1
mauricio Ruiz

Jefe de Sección

Medicina Norte

Hospital Clínico Universidad de Chile

Santiago, Chile

1
Paola Morales

Profesor Asociado

Programa Farmacología Molecular & Clínica, ICBM,

Universidad de Chile

Santiago, Chile

1
Ramiro Zepeda

Academico

Farmacologia y neurociencia

universidad de Chile

santiago, Chile

1
Ramón Sotomayor

Full Professor

Institute of Physiology

UNIVERSIDAD DE VALPARAÍSO, FACULTAD DE CIENCIAS, DEPARTAMENTO DE FISIOLOGÍA

Valparaíso, Chile

1
Caroll Beltrán

Profesor Asistente, Investigador Principal

Medicina

Universidad de Chile, Fac Medicina

SANTIAGO, Chile

1
Juan Peña

Director Medico

Servicios Veterinarios especializados VETCO

santiago, Chile

1
CONSUELO ARIAS

Docente

Ciencias Preclínicas

Universidad de La Frontera

Temuco, Chile

1
VIVIAN LUCHSINGER

Profesor Asociado

Virología

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA.

Santiago, Chile

1
Alejandro Gonzalez

investigador Postdoctoral

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

1
Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

1
Nestor Sepulveda

Profesor Titular A

Producción Agropecuaria

Universidad de La Frontera

TEMUCO, Chile