Man

Matias Escobar Aguirre

Postdoctoral Researcher

University of Pennsylvania

Philadelphia, Chile

Líneas de Investigación


1. Mechanisms of tumor dormancy and recurrence in breast cancer using in vivo models. 2. Cytokine signaling pathways in breast cancer. 3. Development of high-throughput CRISPR/Cas9 technologies to interrogate gene function.

Educación

  •  Cell Biology & Genetics, UNIVERSITY OF PENNSYLVANIA. Chile, 2017
  •  Medical Technology, UNIVERSIDAD DE CHILE. Chile, 2007
  •  Medical Technologist , UNIVERSIDAD DE CHILE. Chile, 2008

Experiencia Académica

  •   Postdoctoral Researcher Full Time

    UNIVERSITY OF PENNSYLVANIA

    Philadelphia, Chile

    2017 - A la fecha

  •   Graduate student Full Time

    UNIVERSITY OF PENNSYLVANIA

    Philadelphia, Chile

    2010 - 2017

Experiencia Profesional

  •   Interno Tecnología Médica Other

    Hospital Jose Joaquin Aguirre

    Santiago, Chile

    2007 - 2007

Formación de Capital Humano


I have extensive teaching experience in the laboratory and the classroom. I taught Genetics and Cell Biology at the undergraduate level in the University of Pennsylvania, top 15 higher-education institution in the world, to students seeking careers in medicine and research in the life sciences. In addition, I have over 7 years of experience teaching and mentoring undergraduate and graduate students in the laboratory. A fundamental part of my proposal is to incorporate students that wish to gain experience in research. I will use the framework of my postdoctoral work to derive a feasible undergraduate thesis project that allows me to teach students how to develop a research question into a well-rounded project with a defined hypothesis and research plan. My teaching approach is to stimulate critical thinking and scientific rigorosity; I combined an intensive training in how to read scientific literature pertaining to cancer biology, while teaching basic lab procedures (laboratory attire, biosafety, lab citizenship, and keeping an organized lab notebook), along with fundamental techniques such as cell culture, PCR, microscopy, and cloning. Equally important is my attention to the student background and skill level, I personalized my mentoring according to their needs and offer additional support if necessary to make the student experience fulfilling. My goal is to provide students with the skills and tools that enables them to take intellectual ownership of their research projects and contribute significantly to the overarching research goal of the laboratory.


Difusión y Transferencia


While I have given multiple talks at specialized conferences during my academic trajectory, I prefer to focus this section in my experience in disseminating scientific knowledge to non-specialized audiences. My experience in activities for the dissemination of scientific information is demonstrated in my active participation in the nonprofit Nexos Chile-USA. I was executive director of Nexos Chile-USA between 2015-2016, and organizer of two conferences in the United States for the Chilean community. In addition, I worked in developing multiple conference programs focused in topics of science policy and science outreach. For instance, I organized a symposium on the topic of “Retribución de Becas Chile” along with researchers in the social sciences, and gave a community engagement talk to nonscientific audience in the importance of the “Genomes”. I believe that activities connecting the public and the research community are a tangible product of scientific research


Premios y Distinciones

  •   Joseph C. Touchstone Research Award

    UNIVERSITY OF PENNSYLVANIA

    Estados Unidos, 2017

    award for excellence in research from the Reproductive department of the University of Pennsylvania


 

Article (7)

Localization in Oogenesis of Maternal Regulators of Embryonic Development
Microtubule-actin crosslinking factor 1 (Macf1) domain function in Balbiani body dissociation and nuclear positioning
Structural and functional properties of ryanodine receptor type 3 in zebrafish tail muscle
Structural evidence for perinuclear calcium microdomains in cardiac myocytes
IP3-dependent, post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers
Visualization of inositol 1,4,5-trisphosphate receptors on the nuclear envelope outer membrane by freeze-drying and rotary shadowing for electron microscopy
Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible robe in cardioprotection
7
Matias Escobar

Postdoctoral Researcher

Cancer Biology

University of Pennsylvania

Philadelphia, Chile

2
Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

2
Julio Cardenas

Associated Professor

Center for Integrative Biology

Universidad Mayor de Chile

Santiago, Chile

2
Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

1
Gonzalo Jorquera

Profesor Auxiliar

Instituto de Fisiología

Universidad de Valparaíso

Valparaíso, Chile

1
Zully Pedrozo

Assistant professor

Physiology and Biophysical

Universidad de Chile

SANTIAGO DE CHILE, Chile

1
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Mariana Casas

Assistant Professor

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
M. Cecilia Hidalgo

Professor

ICBM

Universidad de Chile

Santiago, Chile