Man

M. Cecilia Hidalgo Tapia

Professor

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Functional role of calcium release through Ryanodine Receptors (RyR)/calcium channels of hippocampal neurons. Characterization of how cellular redox state regulates RyR activity, synaptic plasticity and memory.

Educación

  •  Doctora en Ciencias, Mención Biología, Universidad de Chile. Chile, 1969
  •  Bioquímica, Universidad de Chile. Chile, 1965
  •  Ciencias Biologicas, UNIVERSIDAD DE CHILE. Chile, 1969

Experiencia Académica

  •   Professor Full Time

    UNIVERSIDAD DE CHILE

    Medicine

    Santiago, Chile

    1965 - A la fecha

  •   Senior Investigator Part Time

    CENTRO DE ESTUDIOS CIENTIFICOS DE SANTIAGO

    Santiago, Chile

    1984 - 2002

  •   Visiting Fellow Full Time

    NATIONAL INSTITUTE OF HEALTH

    Bethesda, MD, Estados Unidos

    1969 - 1972

  •   ASSOCIATE Part Time

    HARVARD UNIVERSITY

    BOSTON, Estados Unidos

    1979 - 1986

  •   STAFF SCIENTIST Full Time

    BOSTON BIOMEDICAL RESEARCH INSTITUTE

    BOSTON, Estados Unidos

    1974 - 1986

  •   Investigadora Senior Part Time

    Instituto Milenio de Neurociencia Biomedica BNI

    Medicina

    Santiago, Chile

    2011 - A la fecha

  •   Investigadora Senior Part Time

    Instituto Milenio de Neurociencia Biomedica BNI

    Medicina

    Santiago, Chile

    2011 - A la fecha

Formación de Capital Humano


Tutor, PhD thesis Rodrigo Torres, Universidad de Chile

Tutor, PhD thesis J Alex Córdova, Universidad de Chile

Tutor, PhD thesis Ismael Valdés, Universidad de Chile

Tutor, PhD thesis, Jamileth More, Universidad de Chile

Co-Tutor, PhD thesis Alejandra Arias, Universidad de Valparaiso


Premios y Distinciones

  •   National Prize in Natural Sciences

    GOBIERNO DE CHILE

    Chile, 2006

    This prize is awarded every other year to a scientist with a distinguished carrer in natural sciences. I was the first woman to recieve this award


 

Article (101)

N-Methyl-d-Aspartate Receptor Modulation by Nicotinamide Adenine Dinucleotide Phosphate Oxidase Type 2 Drives Synaptic Plasticity and Spatial Memory Impairments in Rats Exposed Pre-and Postnatally to Ethanol
N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer's Disease Rat Model
The signaling pathways underlying BDNF-induced Nrf2 hippocampal nuclear translocation involve ROS, RyR-Mediated Ca2+ signals, ERK and PI3K
Triclosan Impairs Hippocampal Synaptic Plasticity and Spatial Memory in Male Rats
Astaxanthin protects primary hippocampal neurons against noxious effects of A ?-oligomers
Cholesterol removal from adult skeletal muscle impairs excitation-contraction coupling and aging reduces caveolin-3 and alters the expression of other triadic proteins
Glucose-Dependent Insulin Secretion in Pancreatic beta-Cell Islets from Male Rats Requires Ca2+ Release via ROS-Stimulated Ryanodine Receptors
Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2+ release without affecting endoplasmic reticulum Ca2+ content in primary hippocampal neurons
The cholesterol-lowering agent methyl-beta-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle fibers and reduces insulin resistance in obese mice
Contribution of Ca2+ release channels to hippocampal synaptic plasticity and spatial memory. Potential redox modulation
Insulin elicits a ROS-activated and an IP3-dependent Ca2+ release, which both impinge on GLUT4 translocation
Ryanodine receptor-mediated Ca2+ release underlies iron-induced mitochondrial fission and stimulates nnitochondrial Ca2+ uptake in primary hippocampal neurons
Redox-sensitive stimulation of type-1 ryanodine receptors by the scorpion toxin maurocalcine
Sub-lethal levels of amyloid beta-peptide oligomers decrease non-transferrin-bound iron uptake and do not potentiate iron toxicity in primary hippocampal neurons
The Antioxidant N-Acetylcysteine Prevents the Mitochondrial Fragmentation Induced by Soluble Amyloid-beta Peptide Oligomers
Amyloid beta-Peptide Oligomers Stimulate RyR-Mediated Ca2+ Release Inducing Mitochondrial Fragmentation in Hippocampal Neurons and Prevent RyR-Mediated Dendritic Spine Remodeling Produced by BDNF
High-Frequency Field Stimulation of Primary Neurons Enhances Ryanodine Receptor-Mediated Ca2+ Release and Generates Hydrogen Peroxide, Which Jointly Stimulate NF-kappa B Activity
Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation
Iron Mediates N-Methyl-D-aspartate Receptor-dependent Stimulation of Calcium-induced Pathways and Hippocampal Synaptic Plasticity
Modulation of cardiac ryanodine receptor activity by ROS and RNS
Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion
Increased Hippocampal Expression of the Divalent Metal Transporter 1 (DMT1) mRNA Variants 1B and +IRE and DMT1 Protein After NMDA-Receptor Stimulation or Spatial Memory Training
Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide
Mitochondria fine-tune the slow Ca2+ transients induced by electrical stimulation of skeletal myotubes
Parallel activation of Ca2+-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress
Hypoxia stimulates via separate pathways ERK phosphorylation and NF-kappa B activation in skeletal muscle cells in primary culture
NADPH Oxidase and Hydrogen Peroxide Mediate Insulin-induced Calcium Increase in Skeletal Muscle Cells
The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling
Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis
Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible robe in cardioprotection
Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex
Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons
Calcium, iron and neuronal function
Effects of ATP, Mg2+, and redox agents on the Ca2+ dependence of RyR channels from rat brain cortex
A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S-glutathionylation
Effect of iron on the activation of the MAPK/ERK pathway in PC12 neuroblastoma cells
Fast kinetics of calcium dissociation from calsequestrin
Identification of cysteines involved in S-nitrosylation, S-glutathionylation, and oxidation to disulfides in ryanodine receptor type 1
Myotube depolarization generates reactive oxygen species through NAD(P)H oxidase; ROS-elicited Ca2+ stimulates ERK, CREB, early genes
Cross talk between Ca2+ and redox signalling cascades in muscle and neurons through the combined activation of ryanodine receptors/Ca2+ release channels
Effects of S-glutathionylation and S-nitrosylation on calmodulin binding to triads and FKBP12 binding to type 1 calcium release channels
Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle
Signal transduction and gene expression regulated by calcium release from internal stores in excitable cells
Kinetic studies of calcium-induced calcium release in cardiac sarcoplasmic reticulum vesicles
S-glutathionylation decreases Mg2+ inhibition and S-nitrosylation enhances Ca2+ activation of RyR1 channels
Annexin VI is attached to transverse-tubule membranes in isolated skeletal muscle triads
Redox regulation of calcium release in skeletal and cardiac muscle
Sodium transport in triads isolated from rabbit skeletal muscle
SH Oxidation Stimulates Calcium Release Channels (Ryanodine Receptors) From Excitable Cells
Sodium/calcium exchange in amphibian skeletal muscle fibers and isolated transverse tubules
Sulfhydryl oxidation overrides Mg2+ inhibition of calcium-induced calcium release in skeletal muscle triads
ATP stimulation of Na +/Ca 2+ exchange in cardiac sarcolemmal vesicles
Cyclic ADP-ribose activates caffeine-sensitive calcium channels from sea urchin egg microsomes
Ca2+- and pH-dependent Halothane Stimulation of Calcium Release in Sarcoplasmic Reticulum from Frog Muscle.
Calcium dependence of ryanodine-sensitive calcium channels from brain cortex endoplasmic reticulum
Luminal pH regulates calcium release kinetics in sarcoplasmic reticulum vesicles
Protons induce calsequestrin conformational changes
Protons Induce Calsequestrin Conformational Changes. : 2130-2137
Luminal Calcium Regulates Calcium Release in Triads Isolated from Frog and Rabbit Skeletal Muscle.
Luminal Calcium Regulation of Calcium Release from Sarcoplasmic Reticulum.
pH Sensitive Calcium Release in Triads from Frog Skeletal Muscle. Rapid Filtration Studies.
Phospholipase C Activity in Membranes and a Soluble Fraction Isolated from Frog Skeletal Muscle.
Triads and Transverse Tubules Isolated from Skeletal Muscle Contain High Levels of Inositol 1,4,5-Trisphosphate. 268, 1511-1517
Inositol 1, 4, 5-Trisphosphatase Activity in Membranes Isolated from Amphibian Skeletal Muscle.
Sodium/Calcium Exchange in Transverse Tubule Vesicles Isolated from Amphibian Skeletal Muscle.
Sodium-Calcium Exchange in Transverse Tubule Vesicles Isolated from Frog Skeletal Muscle.
Activation of Calcium Channels in Sarcoplasmic Reticulum from Frog Muscle by Nanomolar Concentrations of Ryanodine.
Inositol Trisphosphate and Excitation-Contraction Coupling in Skeletal Muscle.
Calcium Modulation of Phosphoinositide Kinases in Transverse Tubule Vesicles from Frog Skeletal Muscle.
Inositol (1,4,5)-Trisphosphate Activates a Calcium Channel in Isolated Sarcoplasmic Reticulum Membranes.
Lipid-protein Interactions and the Function of the Ca2+-ATPase of Sarcoplasmic Reticulum.
Lipid Composition of Purified Transverse Tubule Membranes Isolated from Amphibian Skeletal Muscle.
Phosphorylation of Phosphatidylinositol by Transverse Tubule Vesicles and its Possible Role in Excitation-Contraction Coupling.
Transverse Tubules from Frog Skeletal Muscle. Purification and Properties of Vesicles Sealed with the Inside-Out Orientation.
Calcium Transport in Transverse Tubules Isolated from Rabbit Skeletal Muscle. Biochem
Ion Pathways in Transverse Tubules. Quantification of Receptors in Membranes Isolated from Frog and Rabbit Skeletal Muscle.
Role of Lipids in Sarcoplasmic Reticulum: A Higher Lipid Content is Required to Sustain Phosphoenzyme Decomposition than Phosphoenzyme Formation.
Lipid Phase of Transverse Tubule Membranes from Skeletal Muscle. An Electron Paramagnetic Resonance Study.
Characterization of the Ca2+-or Mg2+-ATPase of Transverse Tubule Membranes Isolated from Rabbit Skeletal Muscle.
Lipid-Protein Interactions and Calcium Transport in Sarcoplasmic Reticulum.
Lipid-Protein Interactions in Sarcoplasmic Reticulum are not Perturbed by Ionophore A23187.
Reconstitution in Planar Lipid Bilayers of a Ca2+-dependent K+ Channel from Transverse Tubule Membranes Isolated from Rabbit Skeletal Muscle.
Rotational Dynamics of Protein and Boundary Lipid in Sarcoplasmic Reticulum Membranes.
Uncoupling of Ca2+ Transport in Sarcoplasmic Reticulum as a Result of Labeling Lipid Amino Groups and Inhibition of Ca2+-ATPase Activity by Modification of Lysine Residues of the Ca2+-ATPase Polypeptide.
Immunological and Biochemical Properties of Transverse Tubule Membranes Isolated from Rabbit Skeletal Muscle.
Highly Purified Sarcoplasmic Reticulum Vesicles are Devoid of a Ca2+-independent (‘Basal’) ATPase Activity.
Inhibition of Calcium Transport in Sarcoplasmic Reticulum after Modification of Highly Reactive Amino Groups.
Effect of the Lipid Environment on Protein Motion and Enzymatic Activity of the Sarcoplasmic Reticulum Calcium ATPase.
Heterogeneity of SH Groups in Sarcoplasmic Reticulum.
Disposition of Proteins and Aminophospholipids in the Sarcoplasmic Reticulum Membrane.
Induction and General Properties of ß-Galactosidase and ß-Galactoside Permease in Pseudomonas BAL-31.
Stimulation of ß-Galactoside Transport in Pseudomonas BAL-31 by Infection with Bacteriophage PM2.
Role of Phospholipids in the Calcium-dependent ATPase of the Sarcoplasmic Reticulum: Enzymatic and ESR Studies with Phospholipid-Replaced Membranes.
Sarcoplasmic Reticulum from Barnacle Muscle: Composition and Calcium Uptake Properties.
Methylation Pattern of Lambda Deoxyribonucleic Acid.
Methylation of Bacteriophage P1 DNA.
Effect of Stimulation and Hyperpolarization on Non-Electrolyte and Sodium Permeability in Perfused Axons of Squid.
Temperature Dependence of Non-Electrolyte and Sodium Permeability in Giant Axon of Squid.
Effect of Temperature on Resting Potential in Giant Axons of Squid.
Effect of Temperature and Metabolic Inhibitors on Calcium-45 Outflow from Squid Giant Axons.
Sodium Transport Inhibition by Selective Mitochondrial Inhibitors in the Urinary Bladder of the Toad.

Abstract (23)

Role of RyR2-mediated calcium release in synaptic plasticity, learning and memory in control and AD-model rats
Cholesterol accumulation in skeletal muscle: a potential novel targetable pathway in insulin resistance
Abeta oligomers and iron stimulate calcium and ROS-dependent mitochondrial fragmentation in primary hippocampal neurons
Methyl-beta-cyclodextrin increases GLUT4-mediated glucose transport in skeletal muscle fibers from insulin resistant mice
Cell cholesterol levels determine glucose uptake and insulin resistance in skeletal muscle
MITOCHONDRIA MODULATE INTRACELLULAR CALCIUM SIGNALS THAT CONTROL ATP TRANSIENTS INDUCED BY ELECTRICAL STIMULATION OF SKELETAL MYOTUBES
Insulin Induces Intracellular Calcium Transients through Activation of NADPH Oxidase in Myotubes
Ryanodine receptor-mediated calcium release stimulates gene expression in neurons
A role for iron, calcium and reactive oxygen species on hippocampal synaptic plasticity
Depolarization of C2C12 myotubes leads to RyR1 S-glutatbionylation
Mitochondrial Ca2+ transients upon electrical stimulation of skeletal myotubes
TNP-8N(3)-ADP photoinactivation and labelling of sarcoplasmic reticulum of skeletal muscle
Hypoxia induces calcium-dependent ERKs activation in skeletal muscle cells
Physiology and pathology of iron in neuronal function
Regulation of single RyR channels from brain by endogenous modulators
Calcium release mediated by redox activation of ryanodine receptors induces CREB and ERK phosphorylation in N2a cells and hippocampal neurons
Increased cardiac activity enhances RyR2 S-glutathionylation
The Education Committee of the International Union of Biochemistry and Molecular Biology
Redox modification of ryanodine receptor/calcium release channels enhances calcium release in vesicles and stimulates ERK and CREB phosphorylation in neuronal cells in culture
CREB phosphorylation induced by hydrogen peroxide in N2A neurons
Activation and s-glutathiolation of ryanodine receptor/calcium release channels from mammalian skeletal muscle by s-nitrosoglutathione
Cytoplasmic regulation by Ca2+ and Mg2+ of ryanodine receptors/calcium release channels from muscle and brain and its modification by channel oxidation
Oxidation of SH groups attenuates Mg2+ inhibition of calcium release in sarcoplasmic reticulum vesicles from skeletal muscle

Proyecto (22)

Unveiling how neuronal calcium signals reach the nucleus following synapse activation
HIPPOCAMPAL RYANODINE RECEPTORS-CALCIUM RELEASE CHANNELS MEDIATE ACTIVITY-GENERATED POSTSYNAPTIC CALCIUM SIGNALS AND THEIR PROPAGATION TO THE NUCLEUS
Instituto de Ciencias Biomédicas (BNI)
DEFECTIVE CALCIUM/REDOX SIGNALING AND ANOMALOUS ELECTRICAL BRAIN ACTIVITY IN RATS INJECTED WITH AMYLOID BETA OLIGOMERS=> FUNCTIONAL AND BEHAVIORAL CORRELATES WITH ALZHEIMER´S PATIENTS.
Adquisicion de una Ultracentrífuga con 4 rotores
The high ROS content of aged rats alters RyR-mediated calcium-signaling, impairing hipocampal synaptic plasticity and spatial memory
SINTESIS DE COMPUESTOS BIFUNCIONALES COMO POSIBLES AGENTES NEUROPROTECTORES
Instituto de Ciencias Biomédicas (BNI)
Participación de la liberación de calcio mediada por RyR en respuesta a BDNF en la activación de cascadas de señales que inducen la expresión de proteínas esenciales para la plasticidad sináptica y memoria espacial
Participation of Calcium- and Redox-induced Ryanodine Receptor-mediated Calcium Release in Sustained Hippocampal LTP
LA LIBERACION DE CALCIO MEDIADA POR RECEPTORES DE RYANODINA PROMUEVE LA MEMORIA ESPACIAL AL ACTIVAR LA TRANSCRIPCION DE LA PROTEINA QUINASA PKMC Y EL TRANSPORTADOR DE HIERRO DMT1.
ROLE OF RYANODINE RECEPTORS ON NEURONAL CALCIUM SIGNALS AND SYNAPTIC PLASTICITY ALTERATIONS INDUCED BY THE BETA-AMYLOID PEPTIDE.
ACTIVACION Y REGULACION DE LOS CANALES DE LIBERACION DE CALCIO-RECEPTORES DE RYANODINA DE MUSCULO Y NEURONAS
EFECTO DE LA OXIDACION DE GRUPOS SH SOBRE LA ACTIVIDAD DE LOS CANALES DE CALCIO SENSIBLES RYANODINA. MODIFICACION DE LA SENSIBILIDAD A AGONISTAS FISIOLOGICOS.
LIBERACION DE CALCIO INDUCIDA POR DESPOLARIZACION Y AGONISTAS EN TRIADAS AISLADAS DE MUSCULO ESQUELETICO
REGULACION LUMINAL DE LA LIBERACION DE CALCIO EN TRIADAS AISLADAS DE MUSCULO ESQUELETICO
CARACTERIZACION FISIOLOGICA DE LA LIBERACION DE CALCIO EN MUSCULO ESQUELETICO. ESTUDIOS EN VESICULAS AISLADAS
MECANISMOS MOLECULARES DEL ACOPLAMIENTO EXCITACION CONTRACCION EN MUSCULO ESQUELETICO
SINTESIS Y DEGRADACION DE INOSITOL TRISFOSFATO EN MUSCULO ESQUELITICO
EFECTO DE ANESTESICOS GENERALES Y LOCALES SOBRE LA ACTIVIDAD DE CANALES DE CALCIO DE RETICULO SARCOPLASMATICO. MECANISMOS MOLECULARES DE ACTIVACION Y BLOQUEO.
CANALES IONICOS EN MUSCULO ESQUELETICO NORMAL Y DISTROFICO.
ACOPLAMIENTO ENTRE EXCITACION Y CONTRACCION EN MUSCULO ESQUELETICO. ESTUDIOS FISICOS Y BIOQUIMICOS EN MEMBRANAS AISLADAS.

Article (13)

Noxious Iron-Calcium Connections in Neurodegeneration.
Calcium Release Mediated by Redox-Sensitive RyR2 Channels Has a Central Role in Hippocampal Structural Plasticity and Spatial Memory.
Contextual Fear Memory Formation and Destabilization Induce Hippocampal RyR2 Calcium Channel Upregulation
Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism. Front Physiol. 2018 Jun 25;9=>791. doi=> 10.3389/fphys.2018.00791. eCollection 2018
Ryanodine receptor-mediated calcium release has a key role in hippocampal LTD induction
Aging Impairs Hippocampal- Dependent Recognition Memory and LTP and Prevents the Associated RyR Up-regulation.
Calcium Rules.
Development of an iron-selective antioxidant probe with protective effects on neuronal function
Mecp2 Mediates Experience-Dependent Transcriptional Upregulation of Ryanodine Receptor Type-3.
Membrane Cholesterol in Skeletal Muscle=> A Novel Player in Excitation-Contraction Coupling and Insulin Resistance.
RyR2-Mediated Ca(2+) Release and Mitochondrial ROS Generation Partake in the Synaptic Dysfunction Caused by Amyloid β Peptide Oligomers.
Calcium, Reactive Oxygen Species, and Synaptic Plasticity
Calcium, Reactive Oxygen Species, and Synaptic Plasticity.

Review (5)

Crosstalk between calcium and redox signaling: From molecular mechanisms to health implications
A role for reactive oxygen/nitrogen species and iron on neuronal synaptic plasticity
Calcium microdomains and gene expression in neurons and skeletal muscle cells
The ryanodine receptors Ca2+ release channels: Cellular redox sensors?
Redox regulation of RyR-mediated Ca2+ release in muscle neurons

ConferencePaper (3)

Calcium dependence of calcium release channels (ryanodine receptors) from skeletal and cardiac muscle
TNP-8N 3-ADP photoinactivation of the phosphatase activity of FITC-modified SERCA
Activation of Ca2+-induced Ca2+ release through S-glutathionylation of release channels

EditorialMaterial (3)

Amyloid beta-peptide oligomers, ryanodine receptor-mediated Ca2+ release, and Wnt-5a/Ca2+ signaling: opposing roles in neuronal mitochondrial dynamics?
Getting to the Heart of Mechanotransduction
Redox Control of Brain Calcium in Health and Disease

BookWhole (1)

Posttranslational modifications of cardiac ryanodine receptors/calcium release channels by reactive oxygen species and reactive nitrogen species
139
M. Cecilia Hidalgo

Professor

ICBM

Universidad de Chile

Santiago, Chile

30
Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

16
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

12
Andrea Paula

Assistant Professor

Institute for research in Dental Sciences

Universidad de Chile

Santiago, Chile

11
Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

10
Tatiana Adasme

Associate Professor, CIBQA Researcher

Centro Integrativo de Biología y Química Aplicada (CIBQA)

Universidad Bernardo OHiggins

Santiago, Chile

9
Sergio Lavandero

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

8
Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

8
Genaro Barrientos

Profesor Asistente

Fisiologia y Biofisica, ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

6
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

5
Ulrike Kemmerling

Full Professor

ICBM

Facultad de Medicina, Universidad de Chile

Santiago, Chile

4
Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

4
PAOLA HAEGER

Associated professor

Ciencias Biomedicas

Universidad Catolica del Norte

COQUIMBO, Chile

3
Carol San Martín

Profesora Asistente

Universidad Mayor de Chile

Santiago, Chile

3
JAMILETH MORE

Investigador Posdoctoral

Neurologia

Hospital Clinico Universidad de Chile

Santiago, Chile

3
ALEXIS HUMERES

DIRECTOR

MORFOFUNCIÓN

Universidad Diego Portales

SANTIAGO, Chile

3
Maria Behrens

Profesor Titular

Neurología y Neurocirugía, y de Neurociencia

Hospital Clínico Universidad de Chile

Santiago, Chile

2
Andrea Paula-Lima

Profesora Asociada

Instituto de Investigación en Ciencias Odontológicas

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Pabla Aguirre

Asistente de investigación

Biología

Universidad de Chile

Santiago, Chile

2
Denise Riquelme

Adjunct Professor

Biology

Universidad de Santiago

Santiago, Chile

2
Barbara Bruna

Asistente de Investigación Proyecto Fondecyt 1190958

Hospital Clinico universidad de Chile-Universidad de Chile

Santiago, Chile

2
jose valdes

Profesor Asociado

Neurociencia

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Berta Espinosa

Assistant Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

2
Alfredo Criollo

Assistant professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

2
Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Roberto Bravo

Assistant Professor

Institute of Nutrition and Food Technology (INTA), Universidad de Chile

Santiago, Chile

2
Juan Valdés

Head lab

Ciencias Biologicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

1
Rodrigo Herrera Molina

Group Leader (staff member)

Neurochemistry and Molecular Biology

Leibniz Institute for Neurobiology

Magdeburg, Alemania

1
Rodrigo Valenzuela

Postdoctorado

Oftalmología

Universidad de Chile

Santiago, Chile

1
Cesar Osorio

Associate Professor

Kinesiología

Universidad Metropolitana de Ciencias de la Educación

Santiago, Chile

1
Paulina Donoso

Full Professor

Physiology and Biophysics

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Maria Aylwin

Associate Professor

Universidad de Talca

Talca, Chile

1
Rodrigo Troncoso

Assistant professor

Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos

Santiago de Chile, Chile

1
Rodrigo Troncoso

Assistant professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

1
Ariel Contreras

assistance professor

Institute for Research in Dental Science

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Clara Quiroga

Profesor Asistente Adjunto

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

1
José Galaz

Estudiante de Posgrado

Instituto de Investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

1
Matias Escobar

Postdoctoral Researcher

Cancer Biology

University of Pennsylvania

Philadelphia, Chile

1
Karen Castillo

Investigadora Joven

Laboratorio de Sensores Moleculares, Centro Interdisciplinario de Neurociencia de Valparaíso (CINV), Facultad de Ciencias, Universidad de Valparaíso

Valparaiso, Chile

1
Valentina Parra

Profesora Asistente / Assistant Professor

Departamento de Bioquímica y Biología Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Andres Chavez

Full Professor

Neuroscience

Universidad de Valparaiso

Valparaiso, Chile

1
gabriela zavala

Investigador post-doctoral

Cells for Cells

Universidad de los Andes

Santiago, Chile