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Rodrigo Hernán Troncoso Cotal

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

1. Energetic Metabolism 2. Glucocorticoid in Fatty Liver Disease 3. Mechanisms of Physical exercise in Health

Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2009
Pharmaceutical Chemist, UNIVERSIDAD DE CHILE. Chile

Assistant professor Full Time

UNIVERSIDAD DE CHILE

Instituto de Nutrición y Tecnología de los Alimentos

Chile

2014 - 2019
Profesor Asociado Full Time

UNIVERSIDAD DE CHILE

Instituto de Nutrición y Tecnología de los Alimentos

Chile

2020 - A la fecha

Docente Part Time

Universidad San Sebastián

Chile

2014 - 2014

- Master Thesis, Felipe Arata. “Effect of sexual dimorphism on the expression of the glucocorticoid receptor and response genes in skeletal muscle of C57BL / 6J mice fed with a high-fat diet”. Master in Nutrition and Foods. INTA, Universidad de Chile. 2020-in development.

- Doctorate Thesis, Camila Donoso. "Role of the stress response protein FKBP51 in mitochondrial fragmentation and function and insulin resistance in liver cells". Co-Director: Dr. Roberto Bravo. Doctorate in Nutrition and Foods, University of Chile. 2020-in development.

- Doctorate Thesis, Juan Carlos Borquez. "Effect of physical exercise on insulin resistance: Role of the interaction between lipid droplets and mitochondria in hepatocytes in an animal model of nonalcoholic fatty liver disease (NAFLD)". Co-Director: Dr. Víctor Cortes. Doctorate in Nutrition and Foods, University of Chile. 2020-in development.

- Master Thesis, Omara Moya. "Sucralose as a disruptor of hepatic insulin sensitivity". Co-Director: Dr. Roberto Bravo. Master in Nutrition and Foods. INTA, University of Chile. 2019-2021.

- Master Thesis, Pamela Pino. "Effect of sucralose intake on mitochondrial function in a model of hepatic steatosis induced by a high-fat diet". Master in Nutrition and Foods. Co-Director: Dr. Roberto Bravo. INTA, University of Chile. 2019-2021.

- Master Thesis, Stacy Bustos. "Induction of the stress response protein FKBP51 produces hepatic insulin resistance." Master in Nutrition and Foods. INTA, University of Chile. 2019-2021.

- Master Thesis, Andrea Eynaudi. Co-Director: Dra. Valentina Parra. Master in Nutrition and Foods. INTA, University of Chile. 2019-2021.

- Master Thesis, Angie Montaña. "Effect of sucralose on the regulation of autophagy in the mouse hepatocyte cell line HepG2". Co-Director: Dr. Alfredo Criollo. Master in Nutrition and Foods. INTA, University of Chile. 2019-2021.

- Master Thesis, Nicole Cancino. "Expression of myokines IL-6 and myostatin in mouse aorta during physical exercise". Co-Director: Dr. Mario Chiong. Master in Biochemistry, Faculty of Chemistry and Pharmacy, University of Chile. 2019-in development.

- Master Thesis, Laura Quezada. "Effect of chronic physical exercise in the modulation of the hepatic endocannabinoid system in a model of hepatic steatosis due to a high fat diet". Co-Director: Dr. Miguel Llanos. Master in Nutrition and Foods. INTA, University of Chile. 2018-2019.

- Master Thesis, Edson Yañez. "Role of FKBP5 in a glucocorticoid-induced insulin desensitization model". Master in Nutrition and Foods. INTA, University of Chile. 2018-in development.

- Master Thesis, Juan Carlos Bórquez. "Effect of sucralose on mitochondrial oxidative function in the human enterocyte cell line Caco-2". Co-Director: Dr. Robero Bravo. Master in Nutrition and Foods. INTA, University of Chile. 2018-2019.

- Master Thesis, Francisco Pino. "Role of chronic physical exercise in the regulation of lipophagia in a model of hepatic steatosis induced by a high-fat diet". Co-Director: Dra. Alejandra Espinosa. Master in Physiology Faculty of Medicine, University of Chile. 2017- 2018.

- Doctorate Thesis, Carlos Sepúlveda. "Role of the endocannabinoid system in the regulation of autophagy in skeletal muscle". Co-Director: Dr. Miguel Llanos. Doctorate in Nutrition and Foods. University of Chile. 2017- in development.

- Doctorate Thesis, Matías Monsalves. "Effect of ?-hydroxybutyrate supplementation on skeletal muscle mitochondrial function". Co-Director: Dr. Sergio Lavandero. Doctorate in Nutrition and Foods, University of Chile. 2017- in development.

- Doctorate Thesis, Juan Rodriguez. "Role of Notch-1 in metabolic plasticity in cancer cells". Co-Director: Dr. Sandra Hirsch. Doctorate in Nutrition and Foods, University of Chile. 2017- in development.

- Ungraduated Thesis, Jonatan Dassonvalle. "Glucocorticoid resistance in obesity: role of exercise in glucocorticoid sensitivity". Biochemist from the Pontificia Universidad Católica de Valparaiso. 2016-2017.

- Mater Thesis, Camila Donoso. "Physiological role of hydrogen sulfide in skeletal muscle and its relationship with insulin signaling". Co-Director: Dr. Omar Porras. Master in Nutrition and Foods. INTA, University of Chile. 2016-2017.

- Master Thesis, Camila Fuentes. "Palmitate induces cancer stem cell characteristics in the HepG2 liver cancer cell line through activation of the Notch1 signaling pathway." Co-Director: Dr. Sandra Hirsch. Master in Nutrition and Foods, INTA, University of Chile. 2016-2017.

- Master Thesis, INTA. Student: Nicole Aguilera. "Autophagy in skeletal muscle tissue in viscerally obese subjects undergoing an acute exercise session". Co-Director: Dra. María Pía de la Maza. Master in Nutrition and Foods. INTA, University of Chile. 2016-2017.

- Master Thesis, Pamela Recabarren. "Regulation of the endocannabinoid system by glucocorticoids produces a differential regulation in the response to glucocorticoids in the skeletal muscle cell line C2C12." Co-Director: Dr. Miguel Llanos. Master in Nutrition and Foods. INTA, University of Chile. 2016-2017.

- Thesis to apply for the degree of Master in Biotechnology, Andrés Bello University
Student: Claudia Sepúlveda. "Role of the Glucocorticoid Beta receptor in the metabolism of the HepG2 cell line" .INTA, Universidad de Chile. 2015-2017.

- Thesis to apply for the professional title of Pharmaceutical Chemist, Pontificia Universidad Católica de Chile. Student: María Belén Farías. "Determine the role of the glucocorticoid receptor? in autophagy. " INTA, University of Chile. 2014-2016

- Thesis to apply for the professional title of Pharmaceutical Chemist, Pontificia Universidad Católica de Chile. Student: Izela Bernal Sore. "The drug RU486 increases insulin sensitivity through the modulation of the beta glucocorticoid receptor." INTA, University of Chile. 2014-2015

- Thesis to apply for the Master's Degree in Biochemistry, University of Chile. Student: Alejandra Oyarzún. "The inhibitor of Nicotinamide Fosforribosiltransferasa, FK866, promotes desensitization to the insulin response in cardiomyocytes." Co-Director: Dr. Sergio Lavandero. Faculty of Chemical and Pharmaceutical Sciences, University of Chile. 2012-2014.

2019

- Column of Opinion "Healthy Eating and Cancer Prevention: Virtuous Alliance with a Long Way to Go, February 4, Digital Magazine Qué Pasa / La Tercera. https://www.latercera.com/canal/que-pasa/

- Column of Opinion "The Risk of Physical Inactivity: National Survey of Habits of Physical Activity and Sports". January 8, www.inta.cl

- Course "Childhood and adolescent obesity: epidemiology, physiopathology, diagnosis and therapeutic confrontation", 7-8 January, INTA.

2018

- Obesity: a permanent challenge. What is the science of our country doing to attack this phenomenon? October 30, MEDS Clinic.

- Obesity, Nutrition and Physical Activity. Conference on Education, Learning and Prevention of Chronic Diseases for Teachers. August 17, Faculty of Chemical and Pharmaceutical Sciences, University of Chile.

- Obesity, Nutrition and Physical Activity. Conference on Education, Learning and Prevention of Chronic Diseases for Students. August 24, Faculty of Chemical and Pharmaceutical Sciences, University of Chile.

- Obesity, Nutrition and Physical Activity. Science Week. August 10, English University College.

- Role of the skeletal muscle in the control of metabolism and insulin sensitivity. 1º Integral Seminar: "Plasticity of the Skeletal Muscle and Exercise". June 22, MEDS Clinic.

- Extension Course: Physical condition in school stage: A pending challenge, April 23, INTA, University of Chile.

2017
- The movement as an educational tool. Conference on Education, Learning and Prevention of Chronic Diseases for Teachers. October 20, Faculty of Chemical and Pharmaceutical Sciences, University of Chile.

- Physical Activity and Teamwork. Conference on Education, Learning and Prevention of Chronic Diseases for Students. October 13, Faculty of Chemical and Pharmaceutical Sciences, University of Chile.

2016
- "NUTRITION AND PHYSICAL ACTIVITY: THE PERFECT PARTNER TO LIVE HEALTHY". Conference for Teachers: Live Healthy: From Nutrition to Learning. December 16, Faculty of Chemical and Pharmaceutical Sciences, University of Chile.

2015
- Interview Radio Cooperativa, Just Measure Program "Stress-Chronic Diseases".


Palmitic acid control of ciliogenesis modulates insulin signaling in hypothalamic neurons through an autophagy-dependent mechanism Pinto-Nunez, Daniela; Lopez-Gallardo, Erik; Cerda, Mauricio; Troncoso, Rodrigo; Criollo, Alfredo Article ISI CELL DEATH & DISEASE (2022)
Anthocyanins from Aristotelia chilensis Prevent Olanzapine-Induced Hepatic-Lipid Accumulation but Not Insulin Resistance in Skeletal Muscle Cells Salamanca, Catalina; Fajardo, Angelo; Bustos, Catalina; Troncoso, Rodrigo; Pastene-Navarrete, Edgar R.; Cubillos, Francisco A.; Rojo, Leonel E. Article ISI MOLECULES (2021)
Differential Effects of Oleic and Palmitic Acids on Lipid Droplet-Mitochondria Interaction in the Hepatic Cell Line HepG2 Eynaudi, Andrea; Troncoso, Rodrigo Article ISI FRONTIERS IN NUTRITION (2021)
Role of Interleukin-6 in Vascular Health and Disease Hernandez-Vargas, Felipe; Troncoso, Rodrigo; Chiong, Mario Article ISI FRONTIERS IN MOLECULAR BIOSCIENCES (2021)
Soluble Interleukin-6 Receptor Regulates Interleukin-6-Dependent Vascular Remodeling in Long-Distance Runners Hernandez-Diaz, Tomas; Mandiola, Jorge; Bruneau, Nicole; Garcia, Lorena; Troncoso, Rodrigo; Chiong, Mario Article ISI Frontiers in Physiology (2021)
Sucralose Stimulates Mitochondrial Bioenergetics in Caco-2 Cells Bórquez, Juan Carlos; Montana, Alejandra; Troncoso, Rodrigo Article ISI FRONTIERS IN NUTRITION (2021)
beta-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle Morales, Pablo Esteban; Sepulveda, Carlos; Chiong, Mario; Eisner, Veronica; Troncoso, Rodrigo Article ISI NUTRIENTS (2020)
Lipid droplets are both highly oxidized and Plin2-covered in hepatocytes of diet-induced obese mice Nocetti Diego.; Ruiz, Paulina; Valenzuela, Rodrigo; Troncoso, Rodrigo Article ISI APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2020)
Mifepristone for Treatment of Metabolic Syndrome: Beyond Cushing's Syndrome Rojo, Leonel E.; Troncoso, Rodrigo Article ISI FRONTIERS IN PHARMACOLOGY (2020)
Moderate Aerobic Exercise Training Prevents the Augmented Hepatic Glucocorticoid Response Induced by High-Fat Diet in Mice Dassonvalle, Jonatan; Sepulveda, Carlos; Pino, Pamela; Chiong, Mario; Llanos, Miguel; Troncoso, Rodrigo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Exercise regulates lipid droplet dynamics in normal and fatty liver Pino-de la Fuente, Francisco; Sepulveda, Carlos; Chiong, Mario; Llanos, Miguel; Troncoso, Rodrigo Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2019)
Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes Paz Hernandez-Caceres, Maria; Troncoso, Rodrigo; Criollo, Alfredo Article ISI SCOPUS FRONTIERS IN ENDOCRINOLOGY (2019)
Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state? Diaz-Vega, Alexis; Chiong, Mario; Garcia, Lorena; Bambs, Claudia; Troncoso, Rodrigo; Cifuentes, Mariana; Ferreccio, Catterina; Quest, Andrew, F. G.; Criollo, Alfredo Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2018)
Autophagy mediates calcium-sensing receptor-induced TNFα production in human preadipocytes Mattar, Pamela; Fuentes, Cecilia; Troncoso, Rodrigo; Breitwieser, Gerda; Cifuentes, Mariana Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2018)
Hyperosmotic stress stimulates autophagy via polycystin-2 Kretschmar, Catalina; Hernando, Cecilia; Budini, Mauricio Article ISI SCOPUS ONCOTARGET (2017)
Irisin is weakly associated with usual physical activity in young overweight women Tenorio, Beatriz; Jiménez, Teresa; Farias, María Belén; Rodriguez, Juan Manuel Article ISI SCOPUS NUTRICION HOSPITALARIA (2017)
Mifepristone enhances insulin-stimulated Akt phosphorylation and glucose uptake in skeletal muscle cells Bernal-Sore, Izela; Navarro-Marquez, Mario; Diaz-Castro, Francisco; Donoso-Barraza, Camila Article SCOPUS Molecular and Cellular Endocrinology (2017)
Atrial Function Assessed by Speckle Tracking Echocardiography Is a Good Predictor of Postoperative Atrial Fibrillation in Elderly Patients Verdejo, HE; Becerra E.; Zalaquet, R; del Campo, A; Garcia, L; Troncoso, R; Chiong, M; Marín, A; Lavandero, S; Gabrielli, L; et al. Article ISI SCOPUS ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES (2016)
Autophagy Networks in Cardiovascular Diseases Garcia, Lorena; Bustamante, Mario; Pizarro, Marcela; Quiroga, Clara; Westermeier, Francisco; Troncoso, Rodrigo; Maiuri, MC; DeStefano, D Article ISI AUTOPHAGY NETWORKS IN INFLAMMATION (2016)
Basal autophagy protects cardiomyocytes from doxorubicin-induced toxicity Article ISI SCOPUS TOXICOLOGY (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Klionsky, Daniel J.; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Abeliovich, Hagai; Acevedo Arozena, Abraham; Adachi, Hiroaki; Adams, Christopher M; Adams, Peter D; Adeli, Khosrow; et al. Article SCOPUS AUTOPHAGY (2016)
HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor Paredes, F; Parra, V; Torrealba, N; Navarro-Marquez, M; Gatica, D; Bravo Sagua R; Troncoso, R; Pennanen C.; Quiroga, C; Chiong, M; et al. Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2016)
Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival Campos, T.; Ziehe J.; Riquelme O.; Peña, D.; Troncoso, R; Lavandero, S; Morin, V; Pincheira, R; Castro A F. Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Regulation of cardiomyocyte autophagy by calcium Shaikh, Soni; Bravo-Sagua, Roberto; Quest, Andrew F.G. Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2016)
FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes Oyarzún, AP; Westermeier, F; Pennanen C.; Lopez-Crisosto, C; Parra, V; Sotomayor-Flores, C; Sanchez, G; Pedrozo, Z; Troncoso, R; Lavandero, S Article ISI SCOPUS Biochemical Pharmacology (2015)
Unsaturated fatty acids induce non-canonical autophagy Niso-Santano, M; Malik, SA; Pietrocola, F; Bravo-San Pedro, JM; Marino, G; Cianfanelli, V; Ben-Younes, A; Troncoso, R; Markaki, M; Sica, V; et al. Article ISI SCOPUS EMBO Journal (2015)
Alteration in mitochondrial Ca2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes Gutiérrez T.; Parra, V; Troncoso, R; Pennanen C.; Contreras-Ferrat, A; Vásquez-Trincado, C; Morales PE; Lopez-Crisosto, C; Sotomayor-Flores, C; Chiong, M; et al. Article ISI SCOPUS CELL COMMUNICATION AND SIGNALING (2014)
Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance Troncoso, R; Paredes, F; Parra, V; Gatica, D; Vásquez-Trincado, C; Quiroga, C; Bravo Sagua R; Lopez-Crisosto, C; Rodríguez, AE; Oyarzún, AP; et al. Article ISI SCOPUS CELL CYCLE (2014)
Drp1 Loss-of-function Reduces Cardiomyocyte Oxygen Dependence Protecting the Heart From Ischemia-reperfusion Injury Zepeda, Ramiro; Kuzmicic, Jovan; Troncoso, Rodrigo; Pennanen, Christian; Riquelme, Jaime A.; Pedrozo, Zully; Chiong, Mario Article ISI JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2014)
Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NF kappa B-Opa-1 Signaling Pathway Parra, V; Verdejo, HE; Iglewski, M; del Campo, A; Troncoso, R; Jones, D; Zhu, Y; Kuzmicic, J; Pennanen C.; Lopez-Crisosto, C; et al. Article ISI SCOPUS DIABETES (2014)
Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake del Campo, A; Parra, V; Vásquez-Trincado, C; Gutiérrez T.; Morales PE; Lopez-Crisosto, C; Bravo Sagua R; Verdejo, HE; Contreras-Ferrat, A; Troncoso, R; et al. Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Organelle communication: Signaling crossroads between homeostasis and disease Bravo-Sagua, R Article ISI SCOPUS INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2014)
Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death Parra, V; Moraga, F; Kuzmicic, J; Lopez-Crisosto, C; Troncoso, R; Torrealba, N; Criollo, A; Diaz-Elizondo, J; Rothermel, BA; Quest, AFG; et al. Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
Herp depletion protects from protein aggregation by up-regulating autophagy Quiroga, C; Gatica, D; Paredes, F; Bravo, R; Troncoso, R; Pedrozo, Z; Rodríguez, AE; Toro, B; Chiong, M; Hetz, C; et al. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Cell Research (2013)
Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol Ayala, P; Montenegro, J; Vivar, R; Letelier, A; Urroz P.A.; Copaja M; Pivet, D; Humeres, C.; Troncoso, R; Vicencio J.M.; et al. Article ISI SCOPUS Experimental and Molecular Pathology (2012)
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy Troncoso, R; Vicencio J.M.; Parra, V; Nemchenko A.; Kawashima, Y; del Campo, A; Toro, B; Aránguiz, P; Chiong, M; Yakar S.; et al. Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2012)
Mitochondria, Myocardial Remodeling, and Cardiovascular Disease Verdejo, HE; del Campo, A; Troncoso, R; Gutiérrez T.; Toro, B; Quiroga, C; Pedrozo, Z; Muñoz, JP; Garcia, L; Lavandero, S Article ISI SCOPUS CURRENT HYPERTENSION REPORTS (2012)
Beta(2)-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation Aránguiz-Urroz, P; Canales, J; Copaja M; Troncoso, R; Carrillo, C; Lara, H; Lavandero, S; Díaz-Araya, G Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2011)
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress Bravo, R; Parra, V; Troncoso, R; Muñoz, JP; Bui, M; Quiroga, C; Rodríguez, AE; Verdejo, HE; Ferreira, J; Iglewski, M; et al. Article ISI SCOPUS Journal of Cell Science (2011)
Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes Marambio P.; Toro, B; Sanhueza, C; Troncoso, R; Parra, V; Verdejo, H; Garcia, L; Quiroga, C; Munafo, D; Diaz-Elizondo, J; et al. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2010)
Heart energy metabolism and its role in the treatment of heart failure Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca Castro, P; Gabrielli, L; Verdejo, H; Greig, D; Llevaneras, S; Hernández, C; Godoy, I; Jalil, JE; Orellana, P; Mellado, R; et al. Article SCOPUS Revista Medica de Chile (2010)
Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide Muñoz, JP; Chiong, M; Garcia, L; Troncoso, R; Toro, B; Pedrozo, Z; Diaz-Elizondo, J; Salas, D; Parra, V; Hidalgo, C; et al. Article ISI SCOPUS Free Radical Biology and Medicine (2010)
Differential Participation of Angiotensin II Type 1 and 2 Receptors in the Regulation of Cardiac Cell Death Triggered by Angiotensin II Aránguiz-Urroz, P; Soto, D; Contreras, A; Troncoso, R; Chiong, M; Montenegro, J; Venegas, D; Smolic, C; Ayala, P; Thomas, WG; et al. Article ISI SCOPUS AMERICAN JOURNAL OF HYPERTENSION (2009)
Gln(27)-> Glu beta(2)-Adrenergic Receptor Polymorphism in Heart Failure Patients: Differential Clinical and Oxidative Response to Carvedilol Troncoso, R; Moraga, F; Chiong, M; Roldan, J; Bravo, R; Valenzuela, R; Díaz-Araya, G; del Campo, A; Sanhueza, C; Rodriguez, A; et al. Article ISI SCOPUS BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2009)
Trypanosoma cruzi calreticulin: A possible role in Chagas' disease autoimmunity Valck, CE; Molina, MC; Aguilar, L; Rodríguez, M; Maldonado, I; Martínez, R; González, C; Troncoso, R; Lavandero, S; Gingras, AR; et al. Article ISI SCOPUS MOLECULAR IMMUNOLOGY (2009)
Interacción entre los polimorfismos del receptor ß1 y ß2 adrenérgico como predictor de riesgo de insuficiencia cardiaca crónica Moraga, Francisco; Troncoso, Rodrigo; Mellado, Rosemarie; Diaz-Araya, Guillermo; Vukasovic, José Luis; Greig, Douglas; Pérez, Osvaldo; Garcia, Lorena; Roldán, Juan; Ocaranza, Maria Paz; et al. Article SCIELO REVISTA MEDICA DE CHILE (2008)
Hyperosmotic stress-dependent NF kappa B activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes Eisner, V; Criollo, A; Quiroga, C; Olea Azar C.; Santibanez, JF; Troncoso, R; Chiong, M; Díaz-Araya, G; Foncea, R; Lavandero, S Article ISI SCOPUS FEBS LETTERS (2006)
Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure Mc-Nab, P; Quintana, JC; Bittner, A; Greig, D; Vergara, I; Corbalan, R; Copaja M; Díaz-Araya, G; Chiong, M; Troncoso, R; et al. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2005)
Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure Castro, P; Pérez, O; Greig, D; Díaz-Araya, G; Moraga, F; Chiong, M; Troncoso, R; Padilla I.; Corbalan, R; Lavandero, S Article ISI REVISTA ESPANOLA DE CARDIOLOGIA (2004)
Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure Efectos del carvedilol en la capacidad funcional, función ventricular izquierda, catecolaminas y estrés oxidativo en pacientes con insuficiencia cardíaca crónica Castro, P; Pérez, O; Greig, D; Padilla I.; Corbalan, R; Díaz-Araya, G; Moraga, F; Chiong, M; Troncoso, R; Lavandero, S; et al. Article SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2004)


Herp protects Hela cells from oxidative stress-induced cell death Diaz, FIP; Gatica, D; Quiroga, C; Parra, V; Bravo, R; Troncoso, R; Torrealba, N; Navarro, M; Jaimovish, E; Lavandero, S Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2013)
Activity of metalloproteinase-9 is related to oxidative stress in the acute coronary syndrome Bittner, A; Castro, P; Pérez, O; Alcaino H; Troncoso, R; Chiong, M; Díaz-Araya, G; Lavandero, S Abstract ISI EUROPEAN HEART JOURNAL (2006)


Autophagy in the Onset of Atrial Fibrillation Troncoso, R; Verdejo, H; Quiroga, C; Pedrozo, Z; Corbalan, R; Garcia, L BookWhole SCOPUS Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging (2014)
Regulation of autophagy by insulin/IGF-1 signaling pathways Troncoso, R; Campo A.D.; Gatica, D; Paredes, F; Torrealba, N; Pedrozo, Z; Garda L.; Nemchenko A.; Ferdous, A; Gillette, T. G.; et al. BookWhole SCOPUS 53rd Annual Transportation Research Forum, TRF 2012 (2012)


Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome Bittner, A; Alcaino H; Pérez, O; Corbalan, R; Troncoso, R; Chiong, M; Mellado, R; Moraga, F; Zanolli D.; Winter, JL; et al. Letter ISI SCOPUS International Journal of Cardiology (2010)


Exploring the role of the stress-responsive protein FKBP51 in Non-Alcoholic Fatty Liver Disease Troncoso, Rodrigo; Espinosa, Alejandra Proyecto (2019)
AUTOCRINE/PARACRINE INTERLEUKIN-6 AND MYOSTATIN CONTROL OF VSMC DIFFERENTIATION UNDER EXERCISE AND RESTING Chiong, Mario; Troncoso, Rodrigo Proyecto (2018)
Mechanisms of Autophagy in Obesity Criollo, Alfredo; Burgos Patricia; Troncoso, Rodrigo Proyecto *Associate research (2018)
The prognostic role of left atrial and ventricular function and its correlation with multiple biomarkers in patients with new atrial fibrillation Proyecto (2014)
Advanced Center for Chronic Diseases (ACCDiS) KOGAN, MARCELO; Castro, Pablo; Quest, andrew; Troncoso, Rodrigo Proyecto (2013)
The Role of Glucocorticoid Receptor beta in autophagic and metabolic regulation Proyecto (2013)
Glucocorticoides en la inducción de autofagia en células musculares: papel de la vía no genómica en la atrofia muscular Proyecto (0)


Glucocorticoid resistance in chronic diseases Review ISI SCOPUS STEROIDS (2016)
New insights into IGF-1 signaling in the heart Troncoso, R; Ibarra, C; Jaimovich, E; Lavandero, S Review ISI TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Cardiovascular autophagy Concepts, controversies, and perspectives Lavandero, S; Troncoso, R; Rothermel, BA; Martinet, W; Sadoshima, J; Hill, JA Review ISI SCOPUS Autophagy (2013)
Regulation of cardiac autophagy by insulin-like growth factor 1 Troncoso, R; Diaz-Elizondo, J; Espinoza, SP; Oyarzún, AP; Riquelme, JA; Garcia-Carvajal, I; Díaz-Araya, G; Garcia, L; Hill, JA; Lavandero, S Review ISI SCOPUS IUBMB Life (2013)
Cardiomyocyte death: mechanisms and translational implications Chiong, M; Wang, ZV; Pedrozo, Z; Cao, DJ; Troncoso, R; Ibacache, M; Criollo, A; Nemchenko A.; Hill, JA; Lavandero, S Review ISI SCOPUS Cell Death and Disease (2011)
Heart energy metabolism and its role in the treatment of heart failure Castro, P; Gabrielli, L; Verdejo, H; Greig, D; Mellado, R; Concepcion, R; Sepúlveda, L; Garcia, L; Pizarro, M; Pivet, D; et al. Review ISI REVISTA MEDICA DE CHILE (2010)
Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca Castro, Pablo; Gabrielli, Luigi; Verdejo, Hugo; Greig, Douglas; Mellado, Rosemarie; Concepción, Roberto; Sepúlveda, Luis; Vukasovic, José Luis; Garcia, Lorena; Pizarro, Marcela; et al. Review SCIELO REVISTA MEDICA DE CHILE (2010)

MARIA MOLINA

Director

Instituto de Ciencias Biomédicas

Universidad de Chile

INDEPENDENCIA, Chile

Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

María González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

Juan Carlos Quintana

Médico nuclear

Radiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

JORGE JALIL

FULL PROFESSOR

ENFS CARDIOVASCULARES

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, ESCUELA DE MEDICINA

Santiago, Chile

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

fresia ferreccio

Full Professor, Director PhD Epidemiolgy Program

Public Health

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE FACULTAD DE MEDICINA, ESCUELA DE MEDICINA, DEPARTAMENTO DE SALUD PÚBLICA.

Santiago, Chile

Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Claudio Hetz

Deputy Director

INSTITUTO DE CIENCIAS BIOMÉDICAS, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Hernan Lara

Profesor Titular

Bioquimica y Biologia Molecular

U DE CHILE, FAC CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

claudio olea

Full Professor

Inorganica y Analitica

UNIVERSIDAD DE CHILE

Santiago, Chile

Mario Aranda

Full Professor

Pharmacy

Pontificia Universidad Católica de Chile

Santiago, Chile

Rosemarie Mellado

Jefe de carrera / Académica

Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Patricia Burgos

Associate Professor Programa de Doctorado en Biología Celular y Biomedicina CEBICEM

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

María Barrera

ACADEMICO

INSTITUTO DE NUTRICIÓN Y TECNOLOGÍA DE LOS ALIMENTOS

INTA. UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

Claudio Acuña

Profesosr Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Ramon Corbalan

Director

Division of Cardiovascular Diseases

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

Luis Milla

Profesor Asistente

Escuela de Medicina

Universidad de Santiago

Santiago, Chile

Rodrigo Troncoso

Assistant professor

Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos

Santiago de Chile, Chile

Carolina Ribeiro

Assistant Professor

Immunology Program

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

Luis Puente

Academico

Ciencias de los Alimentos y Tecnologia Quimica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Roxana Pincheira

Full Professor

Bioquímica y Biología Celular

Universidad de Concepcion

Concepción, Chile

Ariel Castro

Full Professor

Department of Biochemistry and Molecular Biology

UNIVERSIDAD DE CONCEPCION

concepciòn, Chile

Clara Quiroga

Profesor Asistente Adjunto

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Francisco Tapia

Investigador

Intihuasi

INSTITUTO DE INVESTIGACIONES AGROPECUARIAS (INIA)

La Serena, Chile

Eduardo Couve

Fabián Jaña

Profesor Asistente

Departamento de Ciencias de la Salud

Universidad de Aysén

Coyhaique, Chile

Raúl Vivar

Profesor Asistente

Universidad de Chile

Santiago, Chile

Mario Bustamante

Docente

Universidad Mayor de Chile

Santiago, Chile

Omar Porras

Associate professor

Lab. Biología Celular

UNIVERSIDAD DE CHILE

Santiago, Chile

LORENA AGUILAR

Assistant Professor

Animal Pathology

Faculty of Veterinary Medicine and Livestock Sciences, University of Chile

Santiago, Chile

Ariel Contreras

assistance professor

Institute for Research in Dental Science

UNIVERSIDAD DE CHILE

Santiago, Chile

Mariana Cifuentes

Professor

Instituto de Nutricion y Tecnologia de los Alimentos

INTA UNIVERSIDAD DE CHILE

Santiago, Chile

CLAUDIA BAMBS

PROFESORA ASOCIADA

SALUD PÚBLICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Nicolas Tobar

Assistan Professor

Cellular and molecular Biology Laboratory

Institute of nutrition and food technology

Santiago, Chile

Jaime Riquelme

Assistant Professor

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

ARTURO FERREIRA

FULL PROFESSOR, CHAIR IMMUNOLOGY DISCIPLINARY PROGRAM

IMMUNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

M. Cecilia Hidalgo

Professor

ICBM

Universidad de Chile

Santiago, Chile

Alfredo Molina

Profesor Asistente

Instituto de Investigación en Ciencias Odontológicas

Universidad de Chile

santiago, Chile

Berta Espinosa

Full Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

Alfredo Criollo

Associated Professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

Jovan Kuzmicic

Profesor Asistente

Departamento Salud

Universidad de Los Lagos

Osorno, Chile

Andrea del Campo

Profesor Asistente, Investigador Principal

Departamento de Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

Valentina Parra

Profesora Asistente / Assistant Professor

Departamento de Bioquímica y Biología Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

Roberto Bravo

Assistant Professor

Institute of Nutrition and Food Technology (INTA), Universidad de Chile

Santiago, Chile

Pablo Aránguiz

Jefe de Carrera

Escuela de Ciencias de la Salud

Universidad Vina del Mar

Viña del Mar, Chile

Carlos Villarroel

Académico

Ciencias Forestales

Universidad Católica del Maule

Talca, Chile

Mauricio Budini

Assistant Professor

Facultad de Odonotología

UNIVERSIDAD DE CHILE

Santiago, Chile

Eugenia Morselli

Profesor Asociado de Planta Ordinaria

Fisiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago de Chile, Chile

Luigi Gabrielli

Profesor Asistente

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

Rodrigo Valenzuela

Postdoctorado

Oftalmología

Universidad de Chile

Santiago, Chile

Juan Santibáñez

Professor of Research

Molecular Oncology

Institute for Medical Research

Belgrade, Serbia

Dagoberto Soto

Investigador

Universidad Católica de Chile

santiago, Chile

Ismael Maldonado

Asistente de Investigación

ICA3

Universidad de O'Higgins

San Fernando, Chile

Maria Ocaranza

Full Professor

Cardiovascular Diseases Division

Pontificia Universidad Catolica de Chile

Santiago, Chile

Francisco Cubillos

Investigador Asociado

Departamento de Biologia

Universidad de Santiago de Chile

Santiago, Chile

Rodrigo Troncoso

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

Zully Pedrozo

Associated Professor

Physiology and Biophysical

Universidad de Chile

SANTIAGO DE CHILE, Chile

Veronica Eisner

Associate Professor

Cellular and Molecular Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Rodrigo Valenzuela

Profesor Asociado

Nutrición

Universidad de Chile

Santiago, Chile

Daniela Salas

Claudio Perez

Profesor Asociado

Pontificia Universidad Catolica de Chile

Santiago, Chile

Teresa Jimenez

Nutricionista

INTA

Santiago, Chile

Ramiro Zepeda

Academico

Farmacologia y neurociencia

universidad de Chile

santiago, Chile

Camila López

Mauricio Ibacache

Profesor Asociado

Pontificia Universidad Católica de Chile

santiago centro, Chile

Carlos Sepulveda

Profesor Asistente

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

Cristina Bertocchi

Assistant Professor

Department of Physiology

Pontificia Universidad Católica de Chile

Santiago, Chile

Camila Calfío

Investigador PhD/Jefe de Proyectos

Corp. Centro Internacional de Biomedicina ICC

Santiago, Chile

Matias Monsalves

Profesor Asociado

Instituto de Ciencias de la Rehabilitación

Universidad Andrés Bello

Santiago, Chile

FELIPE CONTRERAS

Professor / Director (Head) Laboratorio Fisiología del Ejercicio

Kinesiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Douglas Greig

Médico Jefe

Cardiología

P. Universidad Católica de Chile

Santiago, Chile

Gonzalo Martínez

Director

División de Enfermedades Cardiovasculares

Hospital Clínico Universidad Católica

Santiago, Chile

Daniel Peña

Profesor Asociado

Universidad San Sebastián

Santiago, Chile

Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

Francisco Fuentes

Profesor Asistente

Departamento de Microbiología

Universidad de Concepción

Concepción, Chile

Ignacio Norambuena

Postdoctorado

Universidad de Chile

Santiago, Chile

Maria Hernandez

Investigador Post Doctoral

Universidad de Chile

Santiago, Chile

Arnaldo Marín

Profesor Adjunto

Basico Clinico de Oncologia

Universidad de Chile

Santiago, Chile

Paulina Villar

Tesista doctorado en bioquímica

Bioquímica

Universidad de Chile

Santiago, Chile

Diego Nocetti

Académico

Tecnología Médica

Universidad de Tarapacá

Arica, Chile

Catalina Kretschmar

Research assistant

Universidad de Chile

Santiago, Chile

Sandra Espinoza

Coordinadora de campo clínico

Tecnología y Ciencias Farmacéuticas

Universidad de Chile

Santiago, Chile

ALEJANDRA SAN MARTIN

Professor

Medicine

Universidad Andrés Bello

Santiago, Chile

Juan Bórquez

Docente

Kinesiologia

Universidad de Magallanes

Punta Arenas, Chile

Fernanda Sanhueza

Bioquímica

Hospital Base San José de Osorno

Osorno, Chile

Jessica Díaz

Profesional especialista

Universidad Andrés Bello

Santiago, Chile

Rodrigo Hernán Troncoso Cotal

Líneas de Investigación

Educación

Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2009

Pharmaceutical Chemist, UNIVERSIDAD DE CHILE. Chile

Experiencia Académica

Assistant professor Full Time

Profesor Asociado Full Time

Experiencia Profesional

Docente Part Time

Formación de Capital Humano

Difusión y Transferencia

Article (50)

Abstract (2)

BookWhole (2)

Letter (1)

Proyecto (7)

Review (7)