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Rodrigo Wladimir Valenzuela Baez

Profesor Asociado

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Ácidos grasos poliinsaturados de cadena larga n-3, aspectos nutricionales, moleculares y efectos cito-protectores.

Educación

  •  Nutrición y Alimentos, UNIVERSIDAD DE CHILE. Chile, 2013
  •  Nutrición y Alimentos, UNIVERSIDAD DE CHILE. Chile, 2007
  •  Nutricionista, UNIVERSIDAD DE CHILE. Chile, 2003
  •  Nutrición y Dietética, UNIVERSIDAD DE CHILE. Chile, 2002

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2007 - A la fecha

Experiencia Profesional

  •   Profesor Asistente Full Time

    Universidad de Chile

    Independencia, Santiago de Chile, Chile

    2007 - A la fecha

  •   Nutricionista Atención Primaria Full Time

    Municipalidad de Paine

    Paine, Chile

    2003 - 2005

  •   Docente Part Time

    Universidad Tecnológica de Chile INACAP

    Santiago, Chile

    2006 - 2007

Formación de Capital Humano


Durante mi labor académica he formado a 6 estudiantes de magíster en Nutrición y Alimentos, y Calidad e Inocuidad alimentaria. Todos han finalizado su formación. Dos de ellos continuaron con estudios de Doctorado en Nutrición y alimentos y dos actualmente son docentes universitarios (Universidad de Chile y Universidad Católica del Maule).


Difusión y Transferencia


Presentaciones (conferencias) en diferentes congresos relacionados con medicina, nutrición, alimentos y salud en general. Respecto al rol de los lipidos y la nutrición para asegurar el adecuado crecimiento y desarrollo de un individuo, así como en la prevención y/o tratamiento de enfermedades.


Premios y Distinciones

  •   Novel Investigator

    International Society for the Study of Fatty Acids and Lipids

    Suecia, 2014

    Premio que reconoce a jóvenes investigadores en lipidos, premio que me permitió asistir al congreso de ISSFAL en Suecia - 2014.

  •   Mejor Docente

    UNIVERSIDAD DE CHILE

    Chile, 2014

    Premio al mejor docente de la carrera de Nutrición y Dietética. Premio entregado por la Universidad, pero que en la elección solamente participan estudiantes de la carrera.


 

Article (46)

Fatty acid and lipid metabolism in liver of pregnant mice and their offspring is influenced by unbalanced folates/vitamin B12 diets
Fatty Acid Profile and Bioactive Compound Extraction in Purple Viper’s Bugloss Seed Oil Extracted with Green Solvents
Combined administration of docosahexaenoic acid and thyroid hormone synergistically enhances rat liver levels of resolvins RvD1 and RvD2
Docosahexaenoic acid and hydroxytyrosol co-administration fully prevents liver steatosis and related parameters in mice subjected to high-fat diet: A molecular approach
Effect of a proanthocyanidin-rich polyphenol extract from avocado on the production of amino acid-derived bacterial metabolites and the microbiota composition in rats fed a high-protein diet
Effects of probe and bath ultrasonic treatments on graphene oxide structure
High-fat diet induces mouse liver steatosis with a concomitant decline in energy metabolism: attenuation by eicosapentaenoic acid (EPA) or hydroxytyrosol (HT) supplementation and the additive effects upon EPA and HT co-administration
Hydroxytyrosol supplementation ameliorates the metabolic disturbances in white adipose tissue from mice fed a high-fat diet through recovery of transcription factors Nrf2, SREBP-1c, PPAR-gamma and NF-kappa B
Impact of anthropometric nutritional parameters on the University Selection Test in Chile=> A multifactorial approach
Profile and distribution of fatty acids in edible parts of commonly consumed marine fishes in Chile
Protective Effect of an Avocado Peel Polyphenolic Extract Rich in Proanthocyanidins on the Alterations of Colonic Homeostasis Induced by a High-Protein Diet
Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1/2 and RvD1/2
Attenuation of High-Fat Diet-Induced Rat Liver Oxidative Stress and Steatosis by Combined Hydroxytyrosol- (HT-) Eicosapentaenoic Acid Supplementation Mainly Relies on HT
Molecular mechanisms related to the hepatoprotective effects of antioxidant-rich extra virgin olive oil supplementation in rats subjected to short-term iron administration
The impact of maternal diet during pregnancy and lactation on the fatty acid composition of erythrocytes and breast milk of chilean women
Comparison of fatty acid profiles of dried and raw by-products from cultured and wild fishes
Hydroxytyrosol and Cytoprotection: A Projection for Clinical Interventions
Hydroxytyrosol prevents reduction in liver activity of Delta-5 and Delta-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice
Molecular adaptations underlying the beneficial effects of hydroxytyrosol in the pathogenic alterations induced by a high-fat diet in mouse liver: PPAR-alpha and Nrf2 activation, and NF-kappa B down-regulation
Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-alpha and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation
Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet
Extra virgin olive oil reduces liver oxidative stress and tissue depletion of long-chain polyunsaturated fatty acids produced by a high saturated fat diet in mice
Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging
Supplementation with antioxidant-rich extra virgin olive oil prevents hepatic oxidative stress and reduction of desaturation capacity in mice fed a high-fat diet: Effects on fatty acid composition in liver and extrahepatic tissues
Upregulation of rat liver PPARα-FGF21 signaling by a docosahexaenoic acid and thyroid hormone combined protocol
Vegetable oils rich in alpha linolenic acid increment hepatic n-3 LCPUFA, modulating the fatty acid metabolism and antioxidant response in rats
Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing
Reduction in the desaturation capacity of the liver in mice subjected to high fat diet: Relation to LCPUFA depletion in liver and extrahepatic tissues
Alpha linolenic acid (ALA) from Rosa canina, sacha inchi and chia oils may increase ALA accretion and its conversion into n-3 LCPUFA in diverse tissues of the rat
N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-alpha upregulation and NF-kappa B DNA binding abrogation
Polyunsaturated Fatty Acid Composition of Maternal Diet and Erythrocyte Phospholipid Status in Chilean Pregnant Women
Vegetable oils rich in alpha linolenic acid allow a higher accretion of n-3 LCPUFA in the plasma, liver and adipose tissue of the rat
Insulin-Dependent H2O2 Production Is Higher in Muscle Fibers of Mice Fed with a High-Fat Diet
Prevention of liver steatosis through fish oil supplementation: correlation of oxidative stress with insulin resistance and liver fatty acid content
Ácido docosahexaenoico (DHA), un ácido graso esencial a nivel cerebral
Bioconversion of alpha-linolenic acid to n-3 LCPUFA and expression of PPAR-alpha, acyl coenzyme A oxidase 1 and carnitine acyl transferase I are incremented after feeding rats with alpha-linolenic acid-rich oils
Cholesterol metabolism: increasingly complex
Evaluation of hepatic bioconversion of alpha- linolenic acid (ALA) to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in rats fed oils from chia (Salvia hispánica) or rosa mosqueta (Rosa rubiginosa)
N-3 Long-Chain Polyunsaturated Fatty Acid Supplementation Significantly Reduces Liver Oxidative Stress in High Fat Induced Steatosis
New dietary sources of alpha-linolenic acid: a critical view
Prevention of liver ischemia reperfusion injury by a combined thyroid hormone and fish oil protocol
OMEGA-3 FATTY ACIDS (EPA AND DHA) AND ITS APPLICATION IN DIVERSE CLINICAL SITUATIONS
Omega-3 fatty acids and cancer, a nutritional alternative for its prevention and treatment
Protection against in vivo liver ischemia-reperfusion injury by n-3 long-chain polyunsaturated fatty acids in the rat
Omega-3 fatty acids, neurodegenerative and psychiatric diseases: A new preventive and therapeutic approach
Docosahexaenoic acid (DHA): A nutritional view for the prevention of Alzheimer's disease

Abstract (1)

Changes in hepatic levels of PPAR-alpha, ACOX and CAT-1 in the prevention of hight fat diet iinduced steatosis

Proyecto (9)

Enzymatic reactions models in supercritical media for obtaining novel structured antioxidant triacylglycerides rich in EPA-DHA as bioactive lipids. Effects on the improvement of biochemical markers associated with obesity
Novel oils for a new nutrition. Towards an improved nutritional quality of edible oils=> innovation and challenges
Educational, socio-economic, neurological, psychological, nutritional, and family variables affecting the University Selection Test (PSU) achievement and later job status=> A ninth-year follow-up study in a multicausal approach
Molecular mechanisms of the protection by oral administration of n-3 long chain polyunsaturated fatty acids and hydroxytyrosol against liver steatosis, oxidative stress, inflammation and insulin resistance induced by high fat diet in mice
Recovery of marine phospholipids rich in n-3 (EPA + DHA) fatty acids and high nutritional value from the residual fat fishmeal
Molecular mechanisms associated with the protection afforded by oral administration of docosahexaenoic acid mixed with extra virgin olive oil against liver steatosis, oxidative stress, inflammation and insulin resistance induced by high fat diet in mice
Prevention of liver steatosis, insulin resistance, oxidative stress and inflammation induced by high fat diet in mice through protocol or combination of polyunsaturated fatty acids long chain ω-3 (EPA + DHA) and extra virgin olive oil.
Evaluación del aceite de Palta como un alimento funcional en la prevención del síndrome metabólico o el control de sus condiciones patológicas asociadas obesidad y resistencia a insulina=> estudios en modelos animales.
Efecto del zinc y adiponectina sobre el transportador de zinc ZNT8=> impacto en la regulación de insulina.

Review (3)

Crosstalk mechanisms in hepatoprotection: Thyroid hormone-docosahexaenoic acid (DHA) and DHA-extra virgin olive oil combined protocols
Relevant Aspects of Nutritional and Dietary Interventions in Non-Alcoholic Fatty Liver Disease
The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity
39
Rodrigo Valenzuela

Profesor Asociado

Nutrición

Universidad de Chile

Santiago, Chile

11
Carlos Valenzuela

INTA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

11
Berta Espinosa

Assistant Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

9
Maria Hernandez

Académico. Profesor Asistente

Nutrición

Universidad de Chile

Santiago , Chile

9
Gladys Tapia

Academica

Farmacología Molecular y Clínica

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

9
Francisca Echeverría

Profesora Asistente

Nutrición

Universidad de Chile

Santiago, Chile

7
Miguel Ángel Rincón

Académico profesor asociado

INSTITUTO DE NUTRICION Y TECNOLOGIA DE LOS ALIMENTOS

Santiago, Chile

4
Amanda D'Espessailles

Investigadora Postdoctoral

Instituto de Ciencias de a Salud

Universidad de O'Higgins

Rancagua, Chile

3
Andres Bustamante

Académico

Nutrición

Universidad de Chile, Facultad de Medicina

Santiago, Chile

3
Nalda Romero

Profesora Asociada

Ciencia de los Alimentos

UNIVERSIDAD DE CHILE

Santiago, Chile

3
Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

2
MARTIN GOTTELAND

Profesor Titular

Facultad de Medicina

Universidad de Chile

Santiago, Chile

2
Daniel Medina

Investigador

Medicina Veterinaria

Universidad San Sebastián

Puerto Montt, Chile

2
Virginia Fernández

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, ICBM, PROGRAMA DE FARMACOLOGÌA

Santiago, Chile

2
Pamela Romanque

Residente

Imagenología

Hospital Clínico Universidad de Chile

Santiago, Chile

2
Paola Navarrete

Associate Professor

INTA

Universidad de Chile

Santiago, Chile

2
paula orellana

nutricionista

APS

CESFAM El Roble

santiago, Chile

2
Reyna Peñailillo

Postdoctorado

Centro de Investigación Biomédica

Universidad de Los Andes

Santiago, Chile

2
Edgar Pastene

Profesor

Ciencias Básias

Universidad del Bío-Bío

Chillán, Chile

2
Alexis Diaz

PhD stundent

Fisiología

universidad de Chile

Santiago, Chile

1
Cristian Campos

Entrenamiento Post Doctorado

Fisiología

Universidad de Chile

Santiago, Chile

1
Nelson Varela

Académico

Oncología Básico-Clínico

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Manuel Ruz

Professor and Chair

Nutrition

DEPARTAMENTO DE NUTRICIÓN, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Francisco Pérez

DIRECTOR

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Jocelyn Fuentes

JEFA DEL LABORATORIO DE ANTIOXIDANTES

INSTITUTO DE NUTRICION Y TECNOLOGIA DE LOS ALIMENTOS

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
JOSE GALGANI

ASSOCIATE PROFESSOR

NUTRITION, DIABETES AND METABOLISM; AND UDA-CIENCIAS DE LA SALUD, NUTRICION Y DIETETICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Ariel Contreras

assistance professor

Institute for Research in Dental Science

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Jessica Zuñiga

Profesor Conferenciante

UNIVERSIDAD DE TALCA

Talca, Chile

1
César Osorio

Associate Professor

Kinesiología

Universidad Metropolitana de Ciencias de la Educación

Santiago, Chile

1
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
manuel melendrez

research Professor

Department of Materials Engineering

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
Katherina Fernandez

Profesor Asociado

Ingeniería Química

UNIVERSIDAD DE CONCEPCIÓN, FAC. INGENIERÍA, DEPTO. INGENIERÍA QUÍMICA

Concepción, Chile

1
Lilia Masson

Presidenta

UNIVERSIDAD DE CHILE

santiago, Chile

1
Hernan Speisky

PROFESOR TITULAR

UNIVERSITY OF CHILE

SANTIAGO, Chile

1
Javier Fernández

Investigador Técnico

Avances Tecnológicos Vertebral

Santiago, Chile