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Manuel Humberto Ruz Ortiz

Professor and Chair

DEPARTAMENTO DE NUTRICIÓN, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


Nutritional and toxicological aspects of micronutrients; Zinc and other minerals in chronic non-communicable diseases, obesity, diabetes; Mineral bioavailability; Mineral-mineral interactions

Educación

  •  Applied Human Nutrition, University of Guelph. Canada, 1990
  •  Nutrition and Health, Universidad de San Carlos / INCAP. Guatemala, 1987
  •  Medical Technologist, UNIVERSIDAD DE CHILE. Chile, 1977

Experiencia Académica

  •   Professor Full Time

    UNIVERSIDAD DE CHILE

    Medicine

    Santiago, Chile

    1977 - A la fecha

  •   Associate researcher Part Time

    Center for studies in sensory imparment aging and metabolism CeSSIAM

    Guatemala city, Guatemala

    1987 - 1987

  •   Research assistant Part Time

    University of Guelph

    College of Family and Consumer Studies

    Guelph, Ontario, Canada

    1987 - 1989

  •   Teaching assistant Part Time

    University of Guelph

    College of Family and Consumer Studies

    Guelph, Ontario, Chile

    1987 - 1989

Experiencia Profesional

  •   Consultant Other

    Free lance

    Santiago, Chile

    1990 - 2000

Formación de Capital Humano


Direction of graduate thesis:

Student: Matías Rivera
Thesis: Effect of zinc supplementation and strength exercise on gene and pretein expresion of metallothioneins and zinc transporters, intracellular zinc flux and insulin sensitivityin muscle in a type 2 diabetes murine model. PhD Program on Nutrition and Food, University of Chile. Underway

Student: Ariel Vivero
Thesis: Effects of a zinc fortified diet and resistance exercise on Akt, PTP1B and IRS-1 phosphorylation, and on non alcoholic liver disease in type 2 diabetic rats. Magister in Nutrition program, INTA, University of Chile. Underway.

Student: María Catalina Hernández
Thesis: Effect of zinc supplementation on fatty acids metabolism in patients with type 2 diabetes PhD Program on Nutrition and Food, University of Chile. Underway

Student: Alvaro Pérez
Thesis: Effect of zinc supplementation on glucagon secretion in type 2 diabetes. PhD Program on Nutrition and Food, University of Chile. Underway 2017.

Student: Verónica Sambra
Thesis: Comparative analysis of apetite/satiety, glycemic and incretin response after non nutrititve sweeteners intake in individuals with type 2 diabetes. Magister in Biological Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 2016

Student: Ivonne Palma
Thesis: Vitamin D satsus in patients with diabetes and normal weight and with obesity. Magister in Medical Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 2015

Student: Paulina Tello
Thesis: Effects of Roux-en-Y gastric bypass and sleeve gastrectomy as treatments for severe and morbid obesity on bone mineral density. Magister in Medical Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 2014

Student: Marianne Gosh
Thesis: Effects of additional zinc supplementation in alopecia development in women undergoing bariatric surgery (sleeve gastrectomy). Magister in Medical Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 2013

Student: Marjorie Sandoval
Thesis: Relative contribution of the nutritional status of micronutrients on cummulative anemia incidence after gastric bypass. Magister in Medical Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 2013

Student: Karen Basfi-fer
Thesis: Bone mineral density assessment in women undergoing gastric bypass receiving two different calcium and vitamin D supplement dose. Magister in Nutrition Program, P Catholic University. 2011

Student: Pamela Rojas
Thesis: Effects of gastric bypass inflammatory, metabolic parameters and iron, zinc and copper markers. Magister in Medical Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 2007

Student: María Eugenia Aguirre
Thesis: Medical-dietetic treatment in obese patients: effects on the nutritional staus of minerals. Magister in Medical Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 2006.

Student: Helena Fernández
Thesis: Effects of iron supplementation on zinc homeostasis. Magister in Biological Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 2003.

Student: Ximena Lara
Thesis: Effects of zinc supplementation on morbidity and immune response in Chilean preschool children. Magister in Medical Sciences, Nutrition, Program. Faculty of Medicine, University of Chile, 1996.


Premios y Distinciones

  •   Rainer Gross Prize

    Hildegard Grunow Foundation

    Alemania, 2012

    The Rainer Gross Award: Recent Innovations in Nutrition and Health in Developing Societies was created by the Hildegard Grunow Foundation to honour the memory of the late Dr. Rainer Gross (http://www.unicef.org/people/people_36064.html) and memorialise his unique approach to innovation in concepts and research in critical — but novel — areas of inquiry, with a view to better the nutrition and health of the less fortunate.


 

Article (77)

Nutritional Effects of Zinc on Metabolic Syndrome and Type 2 Diabetes: Mechanisms and Main Findings in Human Studies
Association between zinc nutritional status and glycemic control in individuals with well-controlled type-2 diabetes
Calcium absorption may be affected after either sleeve gastrectomy or Roux-en-Y gastric bypass in premenopausal women: a 2-y prospective study
Zinc Supplementation Does Not Affect Glucagon Response to Intravenous Glucose and Insulin Infusion in Patients with Well-Controlled Type 2 Diabetes
Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet
Does Zinc Really “Metal” with Diabetes? The Epidemiologic Evidence
Efecto del fraccionamiento de la dieta y cantidad de hidratos de carbono en el control metabólico en pacientes con diabetes mellitus tipo 2, sin terapia con insulina
Micronutrient Deficiencies in Morbidly Obese Women Prior to Bariatric Surgery
Impacto de los ácidos grasos de la dieta sobre el perfil lipídico, sensibilidad a la insulina y funcionalidad de las células β pancreáticas en sujetos diabéticos tipo 2
Micronutrient Deficiencies in Morbidly Obese Women Prior to Bariatric Surgery
Changes in Bone Mineral Density After Sleeve Gastrectomy or Gastric Bypass: Relationships with Variations in Vitamin D, Ghrelin, and Adiponectin Levels
Changes in Bone Mineral Density After Sleeve Gastrectomy or Gastric Bypass: Relationships with Variations in Vitamin D, Ghrelin, and Adiponectin Levels
Cadmium and Lead content in Liver and Kidney tissues of Wild Turkey Vulture Cathartes aura (Linneo, 1758) from Chariaral, Atacama desert, Chile
Cadmium and Lead content in Liver and Kidney tissues of Wild Turkey Vulture Cathartes aura (Linneo, 1758) from Chariaral, Atacama desert, Chile
Zinc as a potential coadjuvant in therapy for type 2 diabetes
Zinc as a potential coadjuvant in therapy for type 2 diabetes
Acute inhibition of iron bioavailability by zinc: studies in humans
Acute inhibition of iron bioavailability by zinc: studies in humans
Changes in ghrelin concentrations one year after resective and non-resective gastric bypass: Associations with weight loss and energy and macronutrient intakes
Changes in ghrelin concentrations one year after resective and non-resective gastric bypass: Associations with weight loss and energy and macronutrient intakes
EVOLUTION OF THE INTAKE AND NUTRITIONAL STATUS OF ZINC, IRON AND COPPER IN WOMEN UNDERGOING BARIATRIC SURGERY UNTIL THE SECOND YEAR AFTER SURGERY
EVOLUTION OF THE INTAKE AND NUTRITIONAL STATUS OF ZINC, IRON AND COPPER IN WOMEN UNDERGOING BARIATRIC SURGERY UNTIL THE SECOND YEAR AFTER SURGERY
Heme- and nonheme-iron absorption and iron status 12 mo after sleeve gastrectomy and Roux-en-Y gastric bypass in morbidly obese women
Heme- and nonheme-iron absorption and iron status 12 mo after sleeve gastrectomy and Roux-en-Y gastric bypass in morbidly obese women
Iron, Copper, and Zinc Transport: Inhibition of Divalent Metal Transporter 1 (DMT1) and Human Copper Transporter 1 (hCTR1) by shRNA
Iron, Copper, and Zinc Transport: Inhibition of Divalent Metal Transporter 1 (DMT1) and Human Copper Transporter 1 (hCTR1) by shRNA
The effect of vitamin A supplementation on retinol concentrations of children with anaemia
ALOPECIA IN WOMEN WITH SEVERE AND MORBID OBESITY WHO UNDERGO BARIATRIC SURGERY
ALOPECIA IN WOMEN WITH SEVERE AND MORBID OBESITY WHO UNDERGO BARIATRIC SURGERY
Quality of the diet of women with severe and morbid obesity undergoing gastric bypass and sleeve gastrectomy
Quality of the diet of women with severe and morbid obesity undergoing gastric bypass and sleeve gastrectomy
Trace Element Status and Inflammation Parameters after 6 Months of Roux-en-Y Gastric Bypass
Trace Element Status and Inflammation Parameters after 6 Months of Roux-en-Y Gastric Bypass
Zinc absorption and zinc status are reduced after Roux-en-Y gastric bypass: a randomized study using 2 supplements
Zinc absorption and zinc status are reduced after Roux-en-Y gastric bypass: a randomized study using 2 supplements
Acute Copper Supplementation Does Not Inhibit Non-Heme Iron Bioavailability in Humans
Acute Copper Supplementation Does Not Inhibit Non-Heme Iron Bioavailability in Humans
COPPER SUPPLEMENTATION DOES NOT INHIBIT IRON ABSORPTION
Effect of helicobacter pylori infection on iron absorption in asymptomatic adults consuming iron and zinc fortified wheat
Changes in Bone Mineral Density, Body Composition and Adiponectin Levels in Morbidly Obese Patients after Bariatric Surgery
Changes in Bone Mineral Density, Body Composition and Adiponectin Levels in Morbidly Obese Patients after Bariatric Surgery
Dietary supplementation with selenomethylselenocysteine produces a differential proteomic response
Dietary supplementation with selenomethylselenocysteine produces a differential proteomic response
Evolution and quality of the diet of women with severe and morbid obesity undergoing gastric bypass
Evolution and quality of the diet of women with severe and morbid obesity undergoing gastric bypass
Iron absorption and iron status are reduced after Roux-en-Y gastric bypass
Iron absorption and iron status are reduced after Roux-en-Y gastric bypass
Organic and inorganic selenium compounds produce different protein patterns in the blood plasma of rats
Energy expenditure and body composition in severe and morbid obese women after gastric bypass
Energy expenditure and body composition in severe and morbid obese women after gastric bypass
Gasto energético y composición corporal en mujeres con obesidad severa y mórbida sometidas a bypass gástrico
Supplementation with zinc between meals has no effect on subsequent iron absorption or on iron status of Chilean women
Supplementation with zinc between meals has no effect on subsequent iron absorption or on iron status of Chilean women
Acute inhibition of iron absorption by zinc
Acute inhibition of iron absorption by zinc
Agreement between measured and calculated by predictive formulas resting energy expenditure in severe and morbid obese women
Agreement between measured and calculated by predictive formulas resting energy expenditure in severe and morbid obese women
Effect of moderate energy-restricted diets on the nutritional status of selected minerals in obese women
Effect of moderate energy-restricted diets on the nutritional status of selected minerals in obese women
New insights about iron bioavailability inhibition by zinc
New insights about iron bioavailability inhibition by zinc
Persistent anemia after Roux-en-Y gastric bypass
Persistent anemia after Roux-en-Y gastric bypass
Zinc inhibits nonheme iron bioavailability in humans
Zinc inhibits nonheme iron bioavailability in humans
Inhibition of iron and copper uptake by iron, copper and zinc
Inhibition of iron and copper uptake by iron, copper and zinc
Zinc supplementation and growth
Zinc supplementation and growth
Zinc absorption from a micronutrient-fortified dried cow's milk used in the Chilean National Complementary Food Program
Zinc absorption from a micronutrient-fortified dried cow's milk used in the Chilean National Complementary Food Program
Association between aminolevulinate dehydrase genotypes and blood lead levels in children from a lead-contaminated area in Antofagasta, Chile
Association between aminolevulinate dehydrase genotypes and blood lead levels in children from a lead-contaminated area in Antofagasta, Chile
Zinc and iron nutrition in Chilean children fed fortified milk provided by the complementary national food program
Zinc and iron nutrition in Chilean children fed fortified milk provided by the complementary national food program
Controlled trial of zinc supplementation on growth and body composition in Chilean children from low income groups
Controlled trial of zinc supplementation in Chilean pregnant adolescents

Abstract (8)

GLYCEMIC INDEX DIET AND RELATION WITH WEIGHT LOSS IN WOMEN WITH SEVERE AND MORBID OBESITY UNDERGOING BARIATRIC SURGERY
ZINC AS A COADJUVANT IN TYPE-2 DIABETES TREATMENT
COPPER SUPPLEMENTATION DOES NOT INHIBIT IRON ABSORPTION
Effect of helicobacter pylori infection on iron absorption in asymptomatic adults consuming iron and zinc fortified wheat
FUTURE PROSPECTS FOR NUTRITION, HEALTH AND POLICY RESPONSES FOR THE SOUTHERN CONE REGION
Inhibition of iron absorption by zinc: Effect of physiological and pharmacological doses
Inhibition of iron absorption by zinc
Zinc absorption from micronutrient-fortified dried cow milk

ConferencePaper (1)

Epidemiology of micronutrient deficiencies in developing and developed countries, specifically zinc, copper, selenium and iodine

EditorialMaterial (1)

The effect of vitamin A supplementation on retinol concentrations of children with anaemia
49
Manuel Ruz

Professor and Chair

Nutrition

DEPARTAMENTO DE NUTRICIÓN, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

25
Fernando Carrasco

Médico nutriólogo

Nutrición y Vida Saludable

Clínica Las Condes

Santiago, Chile

23
Pamela Rojas

Profesor asistente

Nutricion

UNIVERSIDAD DE CHILE

Santiago, Chile

15
Karen Basfi-fer

académico

Departamento de Nutrición

UNIVERSIDAD DE CHILE

Santiago, Chile

4
Álvaro Pérez

Associate Professor

Nutrition

Universidad de Chile

Santiago, Chile

3
Daniela Adjemian

Prof Asistente, Nutrióloga Asistencia Nutricional Intensiva

Cirugía

Hospital Clínico Universidad de Chile

Santiago, Chile

2
Maria Hernandez

Académico. Profesor Asistente

Nutrición

Universidad de Chile

Santiago , Chile

2
JOSE GALGANI

ASSOCIATE PROFESSOR

NUTRITION, DIABETES AND METABOLISM; AND UDA-CIENCIAS DE LA SALUD, NUTRICION Y DIETETICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

1
Berta Espinosa

Assistant Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

1
JOSE SANTOS

Full Professor

Department of Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

1
Francisco Pérez

DIRECTOR

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Rodrigo Valenzuela

Profesor Asociado

Nutrición

Universidad de Chile

Santiago, Chile

1
Ronny Martinez

Académico Investigador

UNIVERSIDAD DE LA SERENA

La Serena, Chile

1
Leslie Landaeta

Profesor investigador

Universidad de Las Américas

Santiago, Chile

1
Nalda Romero

Profesora Asociada

Ciencia de los Alimentos

UNIVERSIDAD DE CHILE

Santiago, Chile