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Ronny Ernesto Martinez Moya

Profesor Asociado

UNIVERSIDAD DE LA SERENA

La Serena, Chile

Líneas de Investigación


Protein Engineering; Enzyme Technology; High Throughput Screening; Bioprocessing

Educación

  •  Biochemical Engineering, JACOBS UNIVERSITY BREMEN. Alemania, 2010
  •  Ingenieria en Biotecnologia Molecular, UNIVERSIDAD DE CHILE. Chile, 2006
  •  Ingeniero en Biotecnologia Molecular, UNIVERSIDAD DE CHILE. Chile, 2007

Experiencia Académica

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE LA SERENA

    Ingeniería

    La Serena, Chile

    2016 - A la fecha

  •   Head of High Throughput Screening Full Time

    RWTH AACHEN UNIVERSITY

    Biology

    Aachen, Alemania

    2010 - 2014

Experiencia Profesional

  •   Group Leader High Throughput Screening Full Time

    RWTH Aachen University

    Aachen, Alemania

    2010 - 2014

  •   PhD fellow Part Time

    Jacobs University Bremen

    Bremen, Alemania

    2007 - 2010

  •   Principal Scientist Biochemistry Full Time

    EW-Nutrition GmbH

    Cologne, Alemania

    2014 - 2016

  •   Académico Full Time

    Universidad de La Serena

    La Serena, Chile

    2016 - A la fecha


 

Article (50)

Enzymatic detection of histamine: Applications, challenges, and improvement potential through biocatalyst engineering
Immobilized biocatalyst engineering: Biocatalytic tool to obtain attractive enzymes for industry
Modulating Substrate Specificity of Rhizobium sp. Histamine Dehydrogenase through Protein Engineering for Food Quality Applications
Valorization of shrimp (Heterocarpus reedi) processing waste via enzymatic hydrolysis: Protein extractions, hydrolysates and antioxidant peptide fractions
Combinatorial InVitroFlow-assisted mutagenesis (CombIMut) yields a 41-fold improved CelA2 cellulase
Effect of process parameters and surfactant additives on the obtained activity of recombinant tryptophan hydroxylase (TPH1) for enzymatic synthesis of 5-hydroxytryptophan (5-HTP)
Effect of the immobilization of pectinase on the molecular weight distribution of pectin oligosaccharides obtained from citrus pectin
Galactaric acid production by engineering substrate specificity in glucose oxidase from Aspergillus niger
Protease-assisted process for tryptophan release from pumpkin (Cucurbita maxima) seed protein extracts
Immobilized Biocatalyst Engineering: High throughput enzyme immobilization for the integration of biocatalyst improvement strategies
Deletion and Randomization of Structurally Variable Regions in B. subtilis Lipase A (BSLA) Alter Its Stability and Hydrolytic Performance Against Long Chain Fatty Acid Esters
Development of alginate-pectin microcapsules by the extrusion for encapsulation and controlled release of polyphenols from papaya (Carica papayaL.)
Improvement of enzymatic performance of Asclepias curassavica L. proteases by immobilization. Application to the synthesis of an antihypertensive peptide
Insights on intermolecular FMN-heme domain interaction and the role of linker length in cytochrome P450cin fusion proteins
Selective immobilization of Bacillus subtilis lipase A from cell culture supernatant: Improving catalytic performance and thermal resistance
Enzyme-assisted extraction of proteins from the seaweeds Macrocystis pyrifera and Chondracanthus chamissoi: characterization of the extracts and their bioactive potential
Enzyme-assisted extraction of proteins from the seaweeds Macrocystis pyrifera and Chondracanthus chamissoi=> characterization of the extracts and their bioactive potential
KnowVolution of a Fungal Laccase toward Alkaline pH
KnowVolution of a Fungal Laccase toward Alkaline pH
A robust protocol for directed aryl sulfotransferase evolution toward the carbohydrate building block GlcNAc
A robust protocol for directed aryl sulfotransferase evolution toward the carbohydrate building block GlcNAc.
Directed evolution of an acid Yersinia mollaretii phytase for broadened activity at neutral pH
Directed evolution of an acid Yersinia mollaretii phytase for broadened activity at neutral pH
Integrating enzyme immobilization and protein engineering: An alternative path for the development of novel and improved industrial biocatalysts
Integrating enzyme immobilization and protein engineering=> An alternative path for the development of novel and improved industrial biocatalysts
Directed evolution of P450cin for mediated electron transfer.
In vitro flow cytometry-based screening platform for cellulase engineering.
Reporter Immobilization Assay (REIA) for Bioconjugating Reactions.
A first continuous 4-aminoantipyrine (4-AAP)-based screening system for directed esterase evolution.
A flow cytometer-based whole cell screening toolbox for directed hydrolase evolution through fluorescent hydrogels.
Advances in protease engineering for laundry detergents
A fluorescent hydrogel-based flow cytometry high-throughput screening platform for hydrolytic enzymes.
Insights on activity and stability of subtilisin E towards guanidinium chloride and sodium dodecylsulfate.
Ionic liquid and deep eutectic solvent-activated CelA2 variants generated by directed evolution.
P-LinK: A method for generating multicomponent cytochrome P450 fusions with variable linker length.
A roadmap to directed enzyme evolution and screening systems for biotechnological applications.
Increasing activity and thermal resistance of Bacillus gibsonii alkaline protease (BgAP) by directed evolution
Increasing protein production by directed vector backbone evolution.
Redirecting catalysis from proteolysis to perhydrolysis in subtilisin Carlsberg.
Reengineering of subtilisin Carlsberg for oxidative resistance
Surface charge engineering of a Bacillus gibsonii subtilisin protease.
An efficient transformation method for Bacillus subtilis DB104
Fluorescent Assay for Directed Evolution of Perhydrolases
Reengineering CelA2 cellulase for hydrolysis in aqueous solutions of deep eutectic solvents and concentrated seawater
A Flow Cytometry–Based Screening System for Directed Evolution of Proteases
Nuclear localization of the mitochondrial ncRNAs in normal and cancer cells
Temperature effects on structure and dynamics of the psychrophilic protease subtilisin S41 and its thermostable mutants in solution
Expression of a family of noncoding mitochondrial RNAs distinguishes normal from cancer cells
Expression of a novel non-coding mitochondrial RNA in human proliferating cells
Inhibition of iron and copper uptake by iron, copper and zinc

Proyecto (6)

A novel deletion/randomization protein engineering strategy and its validation through improvement of B. subtilis lipase A for applied biocatalysis
“Functionalization of polymers –Project part F”
“In vitro Durchmusterungstechnologie für eine Gelenkte Evolutionsrunde pro Tag”
“BioIndustrie2021=> Biokatalyse2021=> Development of new perhydrolases=> Increasing specific perhydrolytic activity and simultaneously decreasing hydrolytic activity”
"BioEnergy 2021=> Research for Biomass utilization"
“Hydrolases from extremophiles for technical applications”
25
Ronny Martinez

Profesor Asociado

Ingenieria en Alimentos

UNIVERSIDAD DE LA SERENA

La Serena, Chile

14
Claudia Bernal

Academica

Departamento de Química

Universidad de La Serena

La Serena, Chile

4
Claudio Villota

Profesor/investigador Asociado

Facultad de Salud

Universidad Bernardo O'Higgins

Santiago, Chile

3
Eduardo Landerer

ENCARGADO POSTGRADO UROLOGÍA HFB

UROLOGÍA

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

3
jaime villegas

Profesor Asistente

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

3
jaime villegas

Investigador Senior

Andes Biotechnologies

Fundación Ciencia para la Vida

Santiago, Chile

3
Luis Burzio

Scientific Director

Andes Biotechnologies

FUNDACION CIENCIA PARA LA VIDA

Santiago, Chile

1
Diana Leiva

Académica e Investigadora

Departamento de Medicina Veterinaria

Universidad del Alba

La Serena, Chile

1
Franko Restovic

Manager

Bioeconomy

Fundación Fraunhofer Chile Research

Santiago, Chile

1
CHRISTOPHER CONCHA

Investigador

Acuicultura

Universidad Católica del Norte

Coquimbo, Chile

1
Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

1
Verónica Burzio

Investigadora Asociada

Fundacion Ciencia y Vida

Santiago, Chile

1
Ricardo Cabrera

Assitant Pofessor

Biology

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Fanny Guzman

Investigador Senior

Núcleo de Biotecnología Curauma

Pontificia Universidad Católica de Valparaiso

Valparaiso, Chile

1
Andrés Illanes

Profesor Títular

Escuela de Ingeniería Bioquímica

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Manuel Ruz

Professor

Nutrition

DEPARTAMENTO DE NUTRICIÓN, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile