Man

Ricardo Mauricio Cabrera Paucar

Assitant Pofessor

UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


Structural Enzymology; bioenergetics of growth in bacteria

Educación

  •  Structural Biology, Metabolism, UNIVERSIDAD DE CHILE. Chile, 2004

Experiencia Académica

  •   Assitant Professor Full Time

    UNIVERSIDAD DE CHILE

    of Sciences

    Santiago, Chile

    2010 - A la fecha

Experiencia Profesional

  •   Assitant Professor Full Time

    Universidad de Chile

    Santiago, Chile

    2010 - A la fecha


 

Article (32)

An NADH preferring acetoacetyl-CoA reductase is engaged in poly-3-hydroxybutyrate accumulation in Escherichia coli
Comparative characterization of the hemocyanin-derived phenol oxidase activity from spiders inhabiting different thermal habitats
Deletion and Randomization of Structurally Variable Regions in B. subtilis Lipase A (BSLA) Alter Its Stability and Hydrolytic Performance Against Long Chain Fatty Acid Esters
Functional characterisation and in silico modelling of MdPSY2 variants and MdPSY5 phytoene synthases from Malus domestica
Fluorescence enzymatic assay for bacterial polyphosphate kinase 1 (PPK1) as a platform for screening antivirulence molecules
Studying the phosphoryl transfer mechanism of the E. coli phosphofructokinase-2=> from X-ray structure to Quantum Mechanics/Molecular Mechanics simulations
Surfaces based on amino acid functionalized polyelectrolyte films towards active surfaces for enzyme immobilization
Cold tolerance mechanisms of two arthropods from the Andean Range of Central Chile=> Agathemera crassa (Insecta=> Agathemeridae) and Euathlus condorito (Arachnida=> Theraphosidae)
Inorganic Polyphosphate, Exopolyphosphatase, and Pho84-Like transporters may be Involved in copper resistance in Metallosphaera sedula DSM 5348T
Understanding the impact of the cofactor swapping of isocitrate dehydrogenase over the growth phenotype of Escherichia coli on acetate by using constraint-based modeling
Datasets for transcriptomics, q-proteomics and phenotype microarrays of polyphosphate metabolism mutants from Escherichia coli.
Multi-level evaluation of Escherichia coli polyphosphate related mutants using global transcriptomic, proteomic and phenomic analyses
Multi-level evaluation of Escherichia coli polyphosphate related mutants using global transcriptomic, proteomic and phenomic analyses.
Determinants of Cofactor Specificity for the Glucose-6-Phosphate Dehydrogenase from Escherichia coli: Simulation, Kinetics and Evolutionary Studies
Determinants of cofactor specificity for the glucose-6-phosphate dehydrogenase from Escherichia coli: Simulation, kinetics and evolutionary studies
Dictyostelium discoideum as a surrogate host-microbe model for antivirulence screening in Pseudomonas aeruginosa PAO1
Polyol specificity of recombinant Arabidopsis thaliana sorbitol dehydrogenase studied by enzyme kinetics and in silico modeling
Metabolic impact of an NADH-producing glucose-6-phosphate dehydrogenase in Escherichia coli
A Ribokinase Family Conserved Monovalent Cation Binding Site Enhances the MgATP-induced Inhibition in E. coli Phosphofructokinase-2
Sorbitol dehydrogenase is a cytosolic protein required for sorbitol metabolism in Arabidopsis thaliana
Modeling the Interfacial Interactions between CrtS and CrtR from Xanthophyllomyces dendrorhous, a P450 System Involved in Astaxanthin Production
The cofactor preference of glucose-6-phosphate dehydrogenase from Escherichia coli- modeling the physiological production of reduced cofactors
The Crystal Complex of Phosphofructokinase-2 of Escherichia coli with Fructose-6-phosphate KINETIC AND STRUCTURAL ANALYSIS OF THE ALLOSTERIC ATP INHIBITION
Ribokinase family evolution and the role of conserved residues at the active site of the PfkB subfamily representative, Pfk-2 from Escherichia coli
Crystallographic Structure of Phosphofructokinase-2 from Escherichia coli in Complex with Two ATP Molecules. Implications for Substrate Inhibition
Unfolding pathway of the dimeric and tetrameric forms of phosphofructokinase-2 from Escherichia coli
Crystallization and preliminary crystallographic analysis of the tetrameric form of phosphofructokinase-2 from Escherichia coli, a member of the ribokinase family
Evidence for a catalytic Mg2+ ion and effect of phosphate on the activity of Escherichia coli phosphofructokinase-2: Regulatory properties of a ribokinase family member
Role of Cys-295 on subunit interactions and allosteric regulation of phosphofructokinase-2 from Escherichia coli
Undergraduate teaching of evolution in chile: more than natural selection
Domain motions and quaternary packing of phosphofructokinase-2 from Escherichia coli studied by small angle X-ray scattering and homology modeling
Ligand-dependent structural changes and limited proteolysis of Escherichia coli phosphofructokinase-2

Abstract (6)

Atomic Force Microscopy Imaging Reveals Structural and Mechanical Properties of Dissociated Hemocyanins by Temperature
Role of the conserved N187 residue of E-coli Pfk-2 in catalysis and allosteric regulation
Thermal unfolding of the dimeric wild-type and a monomeric mutant phosphofructokinase-2 from E-coli
Dimer-tetramer transition and the allosteric regulation of phosphofructokinase-2 from E-coli
On the catalytic role of conserved active site residues D256 and E190 of Escherichia coli Phosphofructokinase-2, a member of the ribokinase family
Allosteric control of the oligomerization of phosphofructokinase-2 from E-coli.

Proyecto (11)

A novel deletion/randomization protein engineering strategy and its validation through improvement of B. subtilis lipase A for applied biocatalysis
Desarrollo, producción y caracterización de anticuerpo recombinante humano contra MIC-A con potencial terapéutico para el tratamiento de cáncer gástrico
Growth bioenergetics and electricity generation at high reducing power in Escherichia coli=> Testing the NADH-NADPH dichotomy
Rewiring supply-demand of reduced power in E. coli=> consequences in growth and bioelectricity
Ingeniería metabólica en plantas, levaduras y bacterias
EQUIPO DE CRISTALIZACION HIGH-TROUGHPUT DE PROTEINAS
REDUCING POWER PRODUCTION IN E. COLI=> A ROLE FOR SPECIFICITY TO NICOTINAMIDE DINUCLEOTIDES OF CENTRAL DEHYDROGENASES
INTEGRACION DE LA BIOLOGIA ESTRUCTURAL AL DESARROLLO DE LA BIONANOTECNOLOGIA
A COMPREHENSIVE MODEL FOR THE MECHANISM OF ALLOSTERIC REGULATION OF E. COLI PHOSPHOFRUCTOKINASE-2. INTEGRATION OF KINETIC, STRUCTURAL, DYNAMIC AND MECHANIC ASPECTS.
METABOLIC EFFECTS OF AN ENGINEERED GLUCOSE-6-P DEHYDROGENASE WITH REVERSED NADP-NAD COFACTOR SPECIFICITY
Distribución de flujos y balance de cofactores en el metabolismo del acetato de E. coli
30
Ricardo Cabrera

Assitant Pofessor

Biology

UNIVERSIDAD DE CHILE

Santiago, Chile

12
Jorge Babul

UNIVERSIDAD DE CHILE

Santiago, Chile

10
Victoria Guixé

Titular Profesor

Biology

UNIVERSIDAD DE CHILE

Santiago, Chile

8
Mauricio Baez

Assistant Professor

Bioquímica y Biología Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Claudia Stange

Titular Professor

Department of Biology

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Michael Handford

Associate Professor

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE BIOLOGÍA

Santiago, Chile

2
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

2
Francisco Chávez

Profesor Asistente

Departamento de Biología

Universidad de Chile

Santiago, Chile

1
Tomás Ossandón

Associate Professor

Medical School, Department of Psychiatry

Pontificia Universidad Católica de Chile

Santiago, Chile

1
CESAR RAMIREZ

Assistant Professor

Institute for Biological and Medical Engineering

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Nelson Barrera

Associate Professor

Physiology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Pablo Maturana

Estudiante de Doctorado

Departamento de Biología

Universidad de Chile

Santiago, Chile

1
JORGE PAVEZ

Professor

Materials Chemistry

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Marcela Urzúa

Associate Professor

Chemistry

UNIVERSIDAD DE CHILE

Santiago, Chile

1
David Rubilar

Curator

Museo Nacional de Historia Natural

Santiago, Chile

1
Jaime Martinez

Investigador

Instituto de Investigaciones Agropecuarias, INIA - La Cruz

La Cruz, Chile

1
Alexander Vargas

Profesor Asociado

Biología

Universidad de Chile

Santiago, Chile

1
Ronny Martinez

Académico Investigador

UNIVERSIDAD DE LA SERENA

La Serena, Chile

1
CHRISTOPHER CONCHA

Investigador

Acuicultura

Universidad Católica del Norte

Coquimbo, Chile

1
Cristina Dorador

PROFESSOR

Biotechnology

UNIVERSIDAD DE ANTOFAGASTA

ANTOFAGASTA, Chile

1
Víctor Cifuentes

Prof. Titular

Departamento de Ciencias Ecológicas

FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE.

Santiago, Chile

1
Marcelo Baeza

Profesor Titular

Ciencias Ecologicas

Universidad de Chile

Santiago, Chile

1
Mauricio Fuentealba

Profesor Adjunto

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Jennifer Alcaíno

Profesor Asociado

Ciencias Ecológicas

UNIVERSIDAD DE CHILE - FACULTAD DE CIENCIAS

Santiago, Chile

1
Nelson Velásquez

Auxiliary Professor

Biology and Chemistry

Catholic University of the Maule

Talca, Chile

1
Pablo Razeto

Researcher

CENTRO NACIONAL DEL MEDIO AMBIENTE

Santiago, Chile

1
Pablo Henny

Profesor Asociado

Anatomía Normal

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Luciano Caputo

Assistant professor

Institute of Marine and Limnology Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Valeria Villalobos

Profesor asistente

Universidad Autónoma de Chile

Santiago, Chile

1
Sergio Álvarez

Profesor Asistente

Bioquímica y Biología Molecular

UNIVERSIDAD DE CHILE. FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Claudia Bernal

Academico Investigador

Ingeniería en Alimentos

Universidad de La Serena

La Serena, Chile

1
Maria Godoy

Coordinadora Científica

ANID

Santiago, Chile