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MIGUEL ARMANDO ARREDONDO OLGUIN

Académico, Profesor Titular

Universidad de Chile, INTA

Santiago, Chile

Micronutrientes Enfermedades Cardiovasculares Metabolismo intracelular de metales trazas

Biología Celular y Molecular, UNIVERSIDAD DE CHILE. Chile, 2002
Ciencias Biológicas, UNIVERSIDAD DE CHILE. Chile, 1996
Tecnólogo Médico, UNIVERSIDAD DE CHILE. Chile, 1983

Académico, Profesor Titular Full Time

INTA

Santiago, Chile

1990 - A la fecha
Académico, Instructor Full Time

UNIVERSIDAD DE ANTOFAGASTA

Facultad de Ciencias de la Salud

Antofagasta, Chile

1983 - 1987

Académico, Profesor Titular Full Time

Universidad de Chile, INTA

Santiago, Chile

1990 - A la fecha


Childhood Obesity and Plasma Micronutrient Deficit of Chilean Children between 4 and 14 Years Old. Castillo Valenzuela, Oscar; Duarte, Lissette; Arredondo-Olguin, Miguel; Iniguez, German; Perez-Bravo, Francisco Article NUTRIENTS (2023)
Modulation of zinc transporter expressions by additional zinc in C2C12 cells cultured in a high glucose environment and in the presence of insulin or interleukin-6. Ruz, Manuel; Andrews-Guzman, Monica; Arredondo-Olguin, Miguel Article BIOLOGICAL TRACE ELEMENT RESEARCH (2022)
Response to Analysis of serum 25-hydroxyvitamin D levels involves taking into account several confounding factors Perez-Bravo, Francisco; Arredondo, Miguel; Castillo, Oscar. Article EUROPEAN JOURNAL OF CLINICAL NUTRITION (2022)
Effect of dietary supplementation with oat beta-glucan for 3 months in subjects with type 2 diabetes: A randomized, double-blind, controlled clinical trial Pino, Jose Luis; Mujica, Veronica; Arredondo, Miguel Article ISI JOURNAL OF FUNCTIONAL FOODS (2021)
Exploratory Study: Excessive Iron Supplementation Reduces Zinc Content in Pork without Affecting Iron and Copper Middleton, Maureen; Olivares, Manuel; Espinoza, Alejandra; Arredondo, Miguel; Pizarro Fernando; Valenzuela, Carolina Article ISI Animals (2021)
Vitamin D status and obesity in children from Chile Perez-Bravo, Francisco; Duarte, Lissette; Arredondo-Olguin, Miguel; Iniguez, German; Castillo-Valenzuela, Oscar Article ISI EUROPEAN JOURNAL OF CLINICAL NUTRITION (2021)
In vitro study of the protective effect of manganese against vanadium-mediated nuclear and mitochondrial DNA damage Rivas-GarcÃa L.; Quiles J.L.; Varela-LÃ³pez A.; Arredondo M.; Lopez P.; DiÃ©guez A.R.; Montes-Bayon M.; Aranda P.; Llopis J.; SÃ¡nchez-GonzÃ¡lez C. Article ISI SCOPUS (2020)
Zinc Modulates the Response to Apoptosis in an In Vitro Model with High Glucose and Inflammatory Stimuli in C2C12 Cells Andrews-Guzman, Monica; Ruz, Manuel.; Arredondo-Olguin, Miguel Article ISI BIOLOGICAL TRACE ELEMENT RESEARCH (2020)
Zinc Supplementation and Strength Exercise in Rats with Type 2 Diabetes: Akt and PTP1B Phosphorylation in Nonalcoholic Fatty Liver Vivero, Ariel; Ruz, Manuel.; Rivera, Matías; Miranda, Karen; Sacristán, Camila; Espinosa, Alejandra; Codoceo,Juana; Inostroza, Jorge; Vásquez, Karla; Pérez, Álvaro; García-Díaz, Diego; Arredondo, Miguel. Article BIOLOGICAL TRACE ELEMENT RESEARCH (2020)
Chronic copper treatment prevents the liver critical balance transcription response induced by acetaminophen Latorre M.; Burkhead J.L.; Hodar C.; Arredondo M.; GonzÃ¡lez M.; Araya M. Article ISI SCOPUS JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2019)
Calcium and zinc decrease intracellular iron by decreasing transport during iron repletion in an in vitro model Monica, A; Lautaro, B; Fernando, P; Miguel, A Article ISI EUROPEAN JOURNAL OF NUTRITION (2018)
Expression of genes associated with inflammation and iron metabolism in 3T3-L1 cells induced with macrophages-conditioned medium, glucose and iron Briones, L; Andrews, M; Pizarro, F; Arredondo-Olguin, M Article ISI SCOPUS BIOMETALS (2018)
miR-155 and miR-122 expression of spermatozoa in obese subjects López, López; Castro, Andrea; Flórez, Martha; Miranda, Karen; Aranda, Pilar; Sánchez-González, Cristina; Llopis, Llopis; Arredondo, Miguel. Article FRONTIERS IN GENETICS (2018)
Calcium and zinc decrease intracellular iron by decreasing transport during iron repletion in an in vitro model Andrews, Mónica; Briones, Lautaro; Pizarro, Fernando Article EUROPEAN JOURNAL OF NUTRITION (2017)
Long-term cognitive functioning in individuals with tyrosinemia type 1 treated with nitisinone and protein-restricted diet García M.I.; de la Parra A.; Arias C.; Arredondo M.; Cabello J.F. Article ISI SCOPUS MOLECULAR GENETICS AND METABOLISM REPORTS (2017)
Prebiotics increase heme iron bioavailability and do not affect non-heme iron bioavailability in humans Weinborn V.; Valenzuela C.; Olivares M.; Arredondo M.; Weill R.; Pizarro F. Article ISI SCOPUS FOOD & FUNCTION (2017)
The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial Mujica V.; Orrego R.; Pérez J.; Romero P.; Ovalle P.; Zúñiga-Hernández J.; Arredondo M.; Leiva E. Article ISI SCOPUS EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2017)
Short repeats in the Heme Oxygenase 1 gene promoter is associated with increased levels of inflammation, ferritin and higher risk of type-2 diabetes mellitus Andrews, Mónica; Leiva, Elba; Arredondo, Miguel Article JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2016)
Short repeats in the Heme Oxygenase 1 gene promoter is associated with increased levels of inflammation, ferritin and higher risk of type-2 diabetes mellitus. Andrews, Mónica; Arredondo, Miguel Article JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2016)
The effect of proteins from animal source foods on heme iron bioavailability in human Pizarro, Fernando; Olivares, Olivares; Valenzuela, Carolina; Brito, Alex; Weinborn, Flores; Sebastián, Arredondo Article FOOD CHEMISTRY (2016)
The effect of proteins from animal source foods on heme iron bioavailability in humans Pizarro F., Olivares M; Valenzuela C, Brito A.; Weinborn, V; Flores S., Arredondo M Article Food Chemistry (2016)
Association between ferritin and hepcidin levels over inflammatory status in patients with type-2 diabetes mellitus and obesity Andrews, Mónica; Soto, Néstor; Arredondo, Miguel. Article NUTRITION (2015)
Association between ferritin and hepcidin levels over inflammatory status in patients with type-2 diabetes mellitus and obesity Andrews, Mónica; Soto, Néstor; Arredondo, Miguel Article NUTRITION (2015)
Effect of phytic acid, tannic acid and pectin on fasting iron bioavailability both in the presence and absence of calcium Jaramillo, A; Briones, L; Andrews M., Arredondo M; Olivares M, Brito A. Article JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2015)
The Effect of Plant Proteins Derived from Cereals and Legumes on Heme Iron Absorption Weinborn, V; Pizarro F., Olivares M; Brito A., Arredondo M; Flores S., Valenzuela C Article Nutrients (2015)
Assessing chaperone for Zn, Cu-superoxide dismutase as an indicator of copper deficiency in malnourished children Arredondo, Miguel; Weisstaub, Gerardo; Medina, Marco; Suazo, Miriam; Guzmán, Marcelo; Araya, Magdalena Article JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2014)
Assessing chaperone for Zn, Cu-superoxide dismutase as an indicator of copper deficiency in malnourished children Arredondo, Miguel; Weisstaub, Gerardo; Medina, Marco; Suazo, Miriam; Araya, Magdalena. Article JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2014)
Effect of Calcium, Tannic Acid, Phytic Acid and Pectin over Iron Uptake in an In Vitro Caco-2 Cell Model Andrews, Mónica; Briones, Lautaro; Jaramillo, Angela; Pizarro, Fernando; Arredondo, Miguel Article BIOLOGICAL TRACE ELEMENT RESEARCH (2014)
Effect of Calcium, Tannic Acid, Phytic Acid and Pectin over Iron Uptake in an In Vitro Caco-2 Cell Model Andrews, Mónica; Briones Lautaro; Jaramillo, Angela; Pizarro, Fernando; Arredondo, Miguel Article BIOLOGICAL TRACE ELEMENT RESEARCH (2014)
Effects of Acute Dietary Iron Overload in Pigs (Sus scrofa) with Induced Type 2 Diabetes Mellitus Espinoza, Alejandra; Morales, Sol; Arredondo, Miguel. Article BIOLOGICAL TRACE ELEMENT RESEARCH (2014)
Mouse divalent metal transporter 1 is a copper transporter in HEK293 cells Arredondo M, Mendiburo; MJ, Flores S.; Singleton, ST; Garrick, MD Article Biometals (2014)
Effects of high iron and glucose concentrations over the relative expression of Bcl2, Bax, and Mfn2 in MIN6 cells Fuentes, Marcela; Andrews, Mónica; Arredondo, Miguel Article BIOLOGICAL TRACE ELEMENT RESEARCH (2013)
High Levels of Iron Status and Oxidative Stress in Patients with Metabolic Syndrome Leiva, Elba; Mujica Verónica, Sepúlveda; Pablo, Guzmán; Luis, Núñez; Sergio, Orrego Roxana; Palomo, Iván; Andrews, Mónica Article BIOLOGICAL TRACE ELEMENT RESEARCH (2013)
Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells Urrutia, Pamela; Aguirre, Pabla; Esparza, Andrés; Tapia, Victoria; Mena, Natalia; Arredondo, Miguel; González-Billaut, Christian; Núñez, Marco T. Article JOURNAL OF NEUROCHEMISTRY (2013)
Administration of high doses of copper to capuchin monkeys does not cause liver damage but induces transcriptional activation of hepatic proliferative responses Araya, Magdalena, Núñez, Héctor; Arredondo, Miguel; Méndez, Marco; Pizarro, Fernando; Uauy, Ricardo; González, Mauricio. Article JOURNAL OF NUTRITION (2012)
Efecto de metformina sobre la expresión del factor de necrosis tumoral-α, los receptores Toll-like 2/4 y la PCR ultra sensible en sujetos obesos con diabetes tipo 2 M Andrews; N Soto; Miguel Arredondo Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2012)
Calcium does not inhibit the absorption of 5 milligrams of nonheme or heme iron at doses less than 800 milligrams in nonpregnant women Gaitán, Diego; Flores, Sebastián; Saavedra, Pía; Miranda, Constanza; Olivares, Manuel; Arredondo, Miguel; López de Romaña, Daniel; Lönnerdal, Bö, Pizarro, Fernando. Article JOURNAL OF NUTRITION (2011)
Effect of dietary protein on heme iron uptake by Caco-2 cells Villarroel, Pía; Flores, Sebastián; Pizarro, Fernando; López de Romaña, Daniel; Arredondo, Miguel. Article EUROPEAN JOURNAL OF NUTRITION (2011)
Transepithelial heme-iron transport: effect of heme oxygenase overexpression Mendiburo, María José; Le Blanc, Solange; Espinoza, Alejandra; Pizarro, Fernando; Arredondo, Miguel. Article EUROPEAN JOURNAL OF NUTRITION (2011)


MICROELEMENTS IN LIFE EXPECTANCY AND AGEING HORIZON 2020, The EU Framework Programme for Research and Innovation (734931) Proyecto 2017-2021 Investigador(a)
INTERACTION BETWEEN SUPPLEMENTAL ZINC AND MUSCLE-STRENGTH TRAINING AS A KEY ELEMENT TO IMPROVE TYPE-2 DIABETES THERAPY FONDECYT (1160792) Proyecto 2016-2019 Coinvestigador(a)
TYING UP LOSSES ENDS ON THE EFFECTS OF IRON AND COPPER ON IRON ABSORPTION FONDECYT (11300075) Proyecto 2013-2015 Coinvestigador(a)
ZINC SUPPLEMENTATION IN TYPE-2 DIABETES=> A RANDOMIZED CLINICAL TRIAL AND MOLECULAR STUDIES OF THE MECHANISMS INVOLVED FONDECYT (1120323) Proyecto 2012-2015 Coinvestigador(a)
ASSOCIATION BETWEEN MICRONUTRIENTS, GROWTH, OBESITY AND OBESITY RELATED DISORDERS IN CHILEAN CHILDREN FONDECYT (1110085) Proyecto 2011-2013 Coinvestigador(a)
INFLAMMATION ASSOCIATED TO THE INCREASE OF ADIPOSE TISSUE MODIFIED HEPCIDIN EXPRESSION, A REGULATORY PROTEIN OF IRON NUTRITION FONDECYT (1110080) Proyecto 2011-2013 Inv. Principal
DESARROLLO DE UN PROVEEDOR DE INGREDIENTES FUNCIONALES POR MEDIO DE LA VALORACIÓN DE RESIDUOS AGROINDUSTRIALES PARA OBTENER ALIMENTOS FUNCIONALES CORFO-INNOVA (2009-7004 / 09CAVC-7004) Proyecto 2010-2012 Coinvestigador(a)
INTERACCIÓN DE LOS GENES DE REGULACIÓN NEGATIVA DEL LINFOCITO T=> CTLA-4 Y PD-1 EN LOS EVENTOS APOPTÓTICOS ASOCIADOS A LA PREDISPOSICIÓN A LA DIABETES TIPO 1 FONDECYT (1100075) Proyecto 2010-2012 Coinvestigador(a)
INTERACCIÓN DE LOS GENES DE REGULACIÓN NEGATIVA DEL LINFOCITO T=> CTLA-4 Y PD-1 EN LOS EVENTOS APOPTÓTICOS ASOCIADOS A LA PREDISPOSICIÓN A LA DIABETES TIPO 1 FONDECYT (1100075) Proyecto 2010-2012 Coinvestigador(a)
INGREDIENTES PATENTABLES PARA LA INDUSTRIA ALIMENTARIA CON POTENCIAL FUNCIONAL EN LA PREVENCIÓN Y CONTROL DE LA OBESIDAD Y DIABETES CORFO-INNOVA (07CT9Z-04) Proyecto 2008-2010 Coinvestigador(a)
POLIMORFISMO EN EL PROMOTOR DEL GEN DE LA HEM OXIGENASA COMO DETERMINANTE DE DEPÓSITOS AUMENTADOS DE HIERRO EN HIJOS DE PACIENTES CON DIABETES MELLITUS TIPO 2 FONDECYT (1085173) Proyecto 2008-2010 Inv. Principal
EXPOSICIÓN A COBRE EN EL SER HUMANO=> POTENCIALES INDICADORES DE EFECTOS TEMPRANOS. FONDECYT (1070595) Proyecto 2007-2010 Coinvestigador(a)
EFECTO DE LAS PROTEINAS DE LA DIETA SOBRE EL MECANISMO DE ABSORCIÓN INTESTINAL DE HIERRO HEMÍNICO. FONDECYT (1061060) Proyecto 2006-2008 Coinvestigador(a)
CERULOPLASMIN AS A POTENTIAL MARKER OF DIFFERENTIAL RESPONSE TO COPPER EXPOSURE IN APPARENTLY International Copper Association (NA) Proyecto 2005-2006 Coinvestigador(a)
EFECTOS DE LA EXPOSICIÓN AGUDA Y CRÓNICA A COBRE EN EL SER HUMANO. FONDECYT (1040979) Proyecto 2004-2006 Coinvestigador(a)
EFFECTS OF ACUTE AND CHRONIC COPPER SUPPLEMENTATION IN HUMANS International Copper Association (NA) Proyecto 2003-2005 Coinvestigador(a)
FACTORES QUE MODULAN LA ABSORCIÓN DE HIERRO HEMÍNICO. FONDECYT (1030633) Proyecto 2003-2005 Coinvestigador(a)