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JAVIER ANDRÉS BRAVO VIVALLO

PROFESOR ADJUNTO

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAISO

VALPARAÍSO, Chile

Líneas de Investigación


BIOCHEMISTRY; NEUROSCIENCE; NEUROGASTROPHARMACOLOGY; Biochemistry and pharmacology of gastrointestinal system; Endocrinology of brain-gut axis

Educación

  •  Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2007
  •  Biochemist, UNIVERSIDAD DE CHILE. Chile, 2002
  •  Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2001

Experiencia Académica

  •   Profesor Adjunto Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Facultad de Ciencias

    VALPARAÍSO, Chile

    2012 - A la fecha

  •   POST-DOCTORAL FELOW Full Time

    UNIVERSITY COLLEGE CORK

    ALIMENTARY PHARMABIOTIC CENTRE (APC)

    CORK, Irlanda

    2007 - 2011

  •   LECTURER Part Time

    UNIVERSIDAD DE CHILE

    FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

    SANTIAGO, Chile

    2006 - 2006

Experiencia Profesional

  •   PROFESOR ADJUNTO Full Time

    PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO

    VALPARAÍSO, Chile

    2012 - A la fecha

  •   POST-DOCTORAL FELLOW Full Time

    UNIVERSITY COLLEGE CORK

    CORK, Irlanda

    2007 - 2011

  •   LECTURER Part Time

    UNIVERSIDAD DE CHILE

    SANTIAGO, Chile

    2006 - 2006


 

Article (31)

Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinction.
Do Obese Bacteria Make us “Want them”? Intestinal Microbiota, Mesocorticolimbic Circuit and Non-Homeostatic Feeding
ANXIOGENIC EFFECTS OF A LACTOBACILLUS, INULIN AND THE SYNBIOTIC ON HEALTHY JUVENILE RATS
Protein Malnutrition During Juvenile Age Increases Ileal and Colonic Permeability in Rats
Intestinal Barrier and Behavior.
What goes around comes around=> novel pharmacological targets in the gut-brain axis.
Association of N-cadherin levels and downstream effectors of Rho GTPases with dendritic spine loss induced by chronic stress in rat hippocampal neurons
Blancos Farmacológicos en el eje intestino-cerebro
Short-term effects of Poly(I:C) on gut permeability
Early-life stress induces persistent alterations in 5-HT1A receptor and serotonin transporter mRNA expression in the adult rat brain
GABAB(1) receptor subunit isoforms differentially regulate stress resilience
Review article: intestinal barrier dysfunction and central nervous system disorders - a controversial association
Differential visceral nociceptive, behavioural and neurochemical responses to an immune challenge in the stress-sensitive Wistar Kyoto rat strain
Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent
Communication between gastrointestinal bacteria and the nervous system
Genetic strain differences in fear inhibition associate with variation in neuroendocrine, autonomic and amygdala dendritic phenotypes
Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action
Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent
MicroRNAs: a novel therapeutic target for schizophrenia.
The Gut-Brain Axis: Ingestion of a Lactobacillus Strain Regulates Emotional Behaviour and Central GABA Receptor Expression in the Mouse via the Vagus Nerve.
A novel role for mGluR7: modulation of faecal water content and colonic electrolyte transport in the Mouse
A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse
Alterations in the Central CRF System of Two Different Rat Models of Comorbid Depression and Functional Gastrointestinal Disorders
Comparison of hippocampal metabotropic glutamate receptor 7 (mGlu7) mRNA levels in two animal models of depression
Comparison of the antidepressant sertraline on differential depression-like behaviors elicited by restraint stress and repeated corticosterone administration
Desipramine prevents stress-induced changes in depressive-like behavior and hippocampal markers of neuroprotection
Adrenalectomy promotes a permanent decrease of plasma corticoid levels and a transient increase of apoptosis and the expression of Transforming Growth Factor β1 (TGF-β1) in hippocampus: Effect of a TGF-β1 oligo-antisense
Effects of long-term adrenalectomy on apoptosis and neuroprotection in the rat hippocampus
Effects of nerve growth factor (NGF) on blood vessels area and expression of the angiogenic factors VEGF and TGFbetaI in the rat ovary
Corticosterone differentially regulates bax, bcl-2 and bcl-x mRNA levels in the rat hippocampus
Adrenalectomy regulates apoptotic-associated genes in rat hippocampus

BookSection (2)

The Future of Prebiotics and Probiotics
What are the possible consequences of chronic stress in central nevous system?

ConferencePaper (5)

Microbiota Intestinal y Estrés
Microbiota intestinal y sistema nervioso
Microbiota y su impacto en la salud mental
Probióticos y Sistema Nervioso Central
The Influence of Intestinal Microbiota on Human Behaviour

ConferencePoster (8)

Anxiogenic effects of probiotics, prebiotics and synbiotic son healthy juvenile rats
Differential effects of SSRIs on rat intestinal permeability and immune response markers
Early-life dysbiosis and its effects on anxiety-like behaviors in the infant rat
Early-life dysbiosis in infant sprague-dawley rats: effect on anxiety-like behaviors and plasma corticosterone levels
Early-life intestinal dysbiosis and its impact on stress-related behaviours in young rats (SIMPOSIO)
Ex-vivo effects of fluoxetine on the rat intestinal barrier: Relevance to disorders of the brain-gut axis
Increased intestinal permeability induced by diet modification: a novel animal model for pharmacological studies of the gut barrier
Rats exposed prenatally to valproate display decreased colonic permeability to macromolecules

Proyecto (16)

Effects of early-life intestinal dysbiosis on the rat’s mesocorticolimbic circuit
OBESITY AND ALTERATIONS OF COLON SUBMUCOSAL NEURONS
THE EFFECT OF ANTIBIOTICS IN EARLY-LIFE ON BRAIN FUNCTION AND BEHAVIOUR
Aumento de la permeabilidad intestinal y activación de neuronas entéricas en ratas con malnutrición
EARLY-LIFE ALTERATIONS OF GUT MICROBIOTA AND ITS IMPACT ON INFANT RAT INTESTINAL BARRIER FUNCTION AND STRESS-RELATED BEHAVIOUR
LA ACTIVACIÓN DEL RECEPTOR TLR-2 MODULA LA PRODUCCIÓN DE UROCORTINA II EN CÉLULAS EPITELIALES HUMANAS DE COLON
ALTERACIONES EN LA FUNCIÓN BARRERA INTESTINAL EN UN MODELO ANIMAL DE AUTISMO
EFECTO DEL ESTRÉS POR SEPARACIÓN MATERNA EN LA EXPRESIÓN DE ARNM DEL RECEPTOR 5-HT1A Y TRANSPORTADOR DE SEROTONINA EN EL CEREBRO DE RATA
USE OF ANTIDEPRESSANTS TO PROTECT INTESTINAL BARRIER FUNCTION
ALTERACIONES EN LA FUNCIÓN BARRERA INTESTINAL EN UN MODELO ANIMAL DE AUTISMO
Aumento de la permeabilidad intestinal y activación de neuronas entéricas en ratas con malnutrición
EARLY-LIFE ALTERATIONS OF GUT MICROBIOTA AND ITS IMPACT ON INFANT RAT INTESTINAL BARRIER FUNCTION AND STRESS-RELATED BEHAVIOUR
EFECTO DE LA MODULACIÓN COLINÉRGICA SOBRE MARCADORES DE INFLAMACIÓN: RELEVANCIA PARA EL SÍNDROME DE INTESTINO IRRITABLE
EFECTO DEL ESTRÉS POR SEPARACIÓN MATERNA EN LA EXPRESIÓN DE ARNM DEL RECEPTOR 5-HT1A Y TRANSPORTADOR DE SEROTONINA EN EL CEREBRO DE RATA
Efectos de prebióticos y probióticos en el sistema nervioso central de la rata juvenil
USE OF ANTIDEPRESSANTS TO PROTECT INTESTINAL BARRIER FUNCTION

Review (4)

Do your gut microbes affect your brain dopamine?
Investigating Gut Permeability in Animal Models of Disease
What goes around comes around: Novel pharmacological targets in the gut-brain axis
Review article: intestinal barrier dysfunction and central nervous system disorders - a controversial association
44
JAVIER BRAVO

PROFESOR ADJUNTO

INSTITUTO DE QUÍMICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAISO

VALPARAÍSO, Chile

10
Marcela Julio

Profesor Adjunto

Instituto de Química

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAISO

Valparaiso, Chile

5
Paola Morales

Profesor Asociado

Programa Farmacología Molecular & Clínica, ICBM,

Universidad de Chile

Santiago, Chile

3
Sergio Cárdenas

Coordinador de Investigación e investigador

Centro de Ingeniería y desarrollo sostenible

Universidad Central de Chile

Santiago, Chile

3
José Ulloa

Profesor asistente

Psicología

Universidad de Talca

Talca, Chile

2
Esteban Aliaga

Profesor

Kinesiología

Universidad Católica el Maule

Talca, Chile

2
Ramón Sotomayor

Full Professor

Institute of Physiology

UNIVERSIDAD DE VALPARAÍSO, FACULTAD DE CIENCIAS, DEPARTAMENTO DE FISIOLOGÍA

Valparaíso, Chile

1
Hernan Lara

Profesor Titular

Bioquimica y Biologia Molecular

U DE CHILE, FAC CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Alfonso Paredes

Investigador principal

Bioquímica y Biología Molecular

University of Chile / Faculty of Chemical Sciences and Pharmacy

Santiago, Chile

1
JENNY FIEDLER

LAB. NEUROPLASTICIDAD Y NEUROGENETICA. DEPTO BIOQUIMICA Y BIOLOGÍA MOLECULAR. FAC. CIENCIAS QUÍMICAS Y FARMACÉUTICAS. UNIVERSIDAD DE CHILE

Santiago, Chile

1
Caroll Beltrán

Profesor Asistente, Investigador Principal

Medicina

Universidad de Chile, Fac Medicina

SANTIAGO, Chile

1
Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

1
Mario Herrera-Marschitz

Profesor titular

Mol. & Clin. Pharmacology

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, PROGRAMA FARMACOLOGIA MOLECULAR & CLINICA, ICBM

Santiago, Chile

1
Waldo Quiroz

Profesor Adjunto

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Alfonso Paredes

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Jonathan Martínez

Profesor ayudante

UNIVERSIDAD DE VALPARAISO

Valparasiso, Chile