Man

ULISES URZUA TOBAR

Assistant Professor

UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


Bases moleculares de la iniciacion y progresion del cancer ovarico. Genomica funcional del cancer Genomica aplicada y Bioinformatica

Educación

  •  Cell & Molecular Biology, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 1999
  •  Biochemist, UNIVERSIDAD DE CHILE. Chile, 1990

Experiencia Profesional

  •   Exchange Scientist Full Time

    SAIC-NCI Frederick

    Frederick MD, Chile

    2001 - 2004


 

Article (37)

Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis
The ovarian transcriptome of reproductively aged multiparous mice: Candidate genes for ovarian cancer protection
Synaptotagmin-1 overexpression under inflammatory conditions affects secretion in salivary glands from Sjogren's syndrome patients
Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjögren's syndrome patients.
Impaired IRE1α/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjögren's syndrome patients.
Oxidative stress in female cancers.
Parity-Dependent Hemosiderin and Lipofuscin Accumulation in the Reproductively Aged Mouse Ovary
Dysregulation of mitotic machinery genes precedes genome instability during spontaneous pre-malignant transformation of mouse ovarian surface epithelial cells
Pro-inflammatory cytokines enhance ERAD and ATF6? pathway activity in salivary glands of Sjögren's syndrome patients
MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome
Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjogren's syndrome?
Tobacco Smoke Activates Human Papillomavirus 16 p97 Promoter and Cooperates with High-Risk E6/E7 for Oxidative DNA Damage in Lung Cells
Biomarkers for screening of lung cancer and pre-neoplastic lesions in a high risk Chilean population
Global transcriptomic analysis uncovers a switch to anaerobic metabolism in tellurite-exposed Escherichia coli
Increased Expression of P2RY2, CD248 and EphB1 in Gastric Cancers from Chilean Patients
Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced beta-catenin/Tcf-Lef dependent transcription
Aberrant localization of fusion receptors involved in regulated exocytosis in salivary glands of Sjogren's syndrome patients is linked to ectopic mucin secretion
Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients
Identification of genes related to nitrogen uptake in wine strains of Saccharomyces cerevisiae
Mechanotransduction and epigenetic control in autoimmune diseases (vol 10, pg 175, 2011)
Nerve Growth Factor Stimulates Cellular Proliferation of Human Epithelial Ovarian Cancer
Alterations in Type I Hemidesmosome Components Suggestive of Epigenetic Control in the Salivary Glands of Patients With Sjogren's Syndrome
Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated With Loss of Cell Polarity and Secretory Dysfunction
Development and validation of a microarray for the confirmation and typing of norovirus RT-PCR products
Disruption of Tight Junction Structure in Salivary Glands From Sjogren's Syndrome Patients Is Linked to Proinflammatory Cytokine Exposure
Gene Regulation by BCL3 in a Cervical Cancer Cell Line
Genomic and phenotypic comparison between similar wine yeast strains of Saccharomyces cerevisiae from different geographic origins
Microarray proteomic analysis discriminates tumorigenic mouse ovarian surface epithelial cells of divergent aggressive potential
Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis
Gene expression and chromosomal location for susceptibility to Sjogren's syndrome
GENE EXPRESSION AND CHROMOSOMAL LOCATION FOR SUSCEPTIBILITY TO SJOGRENS SYNDROME
Differential gene expression in skeletal muscle cells after membrane depolarization
Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: Functional similarity to the human disease and identification of prospective tumoral markers and targets
WebaCGH: An interactive online tool for the analysis and display of array comparative genomic hybridisation data
Microarray comparative genomic hybridization profile of a murine model for epithelial ovarian cancer reveals genomic imbalances resembling human ovarian carcinomas
Oxidation of kojic acid catalyzed by manganese peroxidase from Ceriporiopsis subvermispora in the absence of hydrogen peroxide
Oxalate oxidase from Ceriporiopsis subvermispora: Biochemical and cytochemical studies

Abstract (6)

FREE CIRCULATING DNA LEVELS IN INDIVIDUALS WITH LUNG CANCER RISK AND CHARACTERIZATION OF COPY NUMBER ALTERATIONS.
The transcriptional co-repressor Ski localizes in the pericentromeric region of mitotic chromosomes, regulating the expression of targeted genes at the early G1 phase of the cell cycle
GENOMIC ALTERATION IN SPUTUM SAMPLES AND DNAFC OF LUNG CANCER HIGH RISK CHILEAN POPULATION
ALTERATIONS OF VAMP2 AND SINTAXIN-2 IN SALIVARY ACINAR CELLS MODIFY THE SECRETION PROCESS IN SJOGREN'S SYNDROME PATIENTS
BIOLOGICAL BIOMARKERS FOR SCREENING OF PRE NEOPLASTIC LESIONS ASSOCIATED TO LUNG CANCER IN A RISK CHILEAN POPULATION
Transcriptional profile of the salivary gland epithelium in Sjogren's syndrome patients

ConferencePaper (2)

Plasma polyphenols and antioxidants, oxidative DNA damage and endothelial function in a diet and wine intervention study in humans
Oxalate metabolism in liquid cultures of Ceriporiopsis subvermispora: A possible pathway for extracellular H 2O 2 production

Proyecto (6)

OVARIAN CANCER INITIATION AND SPREAD IN A SYNGENEIC MOUSE MODEL AT ESTROPAUSAL STATE
"SKI-CONTAINING TRANSCRIPTIONAL CO-REPRESSOR COMPLEXES ON MITOTIC CHROMOSOMES REPRESS THE EXPRESSION OF SELECTED TARGET GENES AT EARLY G1."
Desarrollo de biomarcadores genómicos como herramientas en la detección temprana y prevención del cáncer pulmonar
BIOMARKERS FOR IDENTIFICATION CHILEAN INFANTS AT RISK FOR RESPIRATORY SUNCYTIAL VIRUS (RSV) AND RHINOVIRUS (RV)- INDUCED SEVERE ACUTE LOWER RESPIRATORY INFECTION
Prevención y detección temprana de cáncer pulmonar basada en genómica e imagenología de punta
Detección de alteraciones transcripcionales y genómicas en cáncer ovárico epitelial

Review (3)

Oral dryness in Sjogren's syndrome patients. Not just a question of water
Sjogren's syndrome and the epithelial target: A comprehensive review
Mechanotransduction and epigenetic control in autoimmune diseases
43
ULISES URZUA

Assistant Professor

ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

19
Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

11
Claudio Molina

Director Investigación

Investigación

Universidad San Sebastián

Santiago, Chile

9
Sergio González

Profesor titular

Patología General y Oral

Universidad Mayor

Santiago, Chile

8
Isabel Castro

Profesor Asistente

Tecnología Médica

Universidad de Chile

Santiago, Chile

6
Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

3
Amelina Albornoz

Post doctorado

Virología Molecular

Fundación Ciencia & Vida

Santiago, Chile

3
Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

2
Diego Carrillo

Asistente de investigación

Virologia

Universidad de Chile

Santiago, Chile

2
MARIA GANGA

academico jornada completa

Departamento en Ciencia y Tecnologia de los Alimentos

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2
Francisco Salinas

Profesor Auxiliar

Instituto de Bioquímica y Microbiolgía

Universidad Austral de Chile

Valdivia, Chile

2
Claudio Martinez

Profesor Titular

Departamento de Ciencia y Tecnología de Alimentos

Universidad de Santiago de Chile

Santiago, Chile

2
Sergio Aguilera

Reumatólogo

CLÍNICA INDISA

Santiago, Chile

1
Katherine Marcelain

Profesora Asociada

Oncología Básico Clínica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

1
Dinka Mandakovic

Profesora Asistente

Centro GEMA

Universidad Mayor de Chile

Santiago, Chile

1
Roberto Molina

Investigador Científico

Biología

Centro de Estudios Científicos

Valdivia, Chile

1
Gisela Aquea

INVESTIGADORA

MEDICINA

UNIVERSIDAD CATOLICA DEL NORTE

COQUIMBO, Chile

1
Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

1
David Diaz

Asistente de Investigación

Instituto de Ciencias Biomédicas, Facultad de Medicina

Universidad de Chile

Santiago, Chile

1
Manuel Espinoza

Profesor Asociado

Salud Pública

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Angela Contreras

Investigador

Pontificia Universidad Católica de Chile

santiago, Chile

1
Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

1
Ricardo Verdugo

Asistant Professor

Facultad de Medicina

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Juan Madariaga

Jefe Unidad

Hospital Coquimbo

Coquimbo, Chile

1
ALEJANDRO CORVALAN

Associate Professor

Hematology and Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Jonas Chnaiderman

Profesor Asociado

Instituto de Ciencias Biomédicas

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Felipe Arenas

Profesor Asociado

Biología

UNIVERSIDAD SANTIAGO DE CHILE

Santiago, Chile

1
Francisco Aguayo

Profesor Asociado

Departamento de Oncología Básico Clínica

Universidad de Chile

Santiago, Chile

1
José Pérez

Associate Professor

Biologia

Universidad Andres Bello

Santiago, Chile

1
Giuliano Bernal

Profesor Titular

Ciencias Biomédicas

UNIVERSIDAD CATÓLICA DEL NORTE

Coquimbo, Chile

1
Julio Tapia

Associate Professor

Program of Cellular and Molecular Biology

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

1
Maria Vega

Academico Profesora Titular

Obstetricia y Ginecologia Campus Norte

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

1
CARLOS ROSAS

Profesor Asistente

Ciencias Morfológicas

Universidad San Sebastián

Santiago, Chile

1
DENISSE SEPULVEDA

Postdoc

Universidad Mayor de Chile

Santiago, Chile

1
veronica garcia

academico

DECYTAL

Universidad de Santaigo

Estación central, Chile

1
Luisa Herrera

Profesor Asociado

Incstituto de Ciencias Biomédicas, Programa de Genética Humana

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA-ICBM

Santiago, Chile

1
Miguel O'Ryan

Profesor Titular

Programa de Microbiologia y Micologia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Yalda Lucero

Profesor Asistente

Programa de Microbiología y Micología; Departamento de Pediatría y Cirugía infantil;

DIVISIÓN NORTE, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE, DEPARTAMENTO DE PEDIATRÍA Y CIRUGÍA INFANTIL-HOSPITAL LUIS CALVO MACKENNA

Santiago, Chile

1
Domingo Lancellotti

Académico

Departamento de Salud Pública

Universidad Católica del Norte

Coquimbo, Chile

1
Rancés Blanco

Investigador Postdoctoral

Virología

Universidad de Chile

Santiago de Chile, Chile