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Rodrigo Alonso Morales Castro

Postdoctoral researcher

Karolinska Institutet

Stockholm, Suecia

I currently work with zebrafish and 3D culture systems to address the role of genetic and environmental factors in the pathogenesis of Inflammatory bowel disease (IBD)

Molecular, Cell Biology and Neuroscience, UNIVERSIDAD DE CHILE. Chile, 2018
Engineer in Molecular Biotechnology, UNIVERSIDAD DE CHILE. Chile, 2013

Postdoctoral researcher Full Time

Karolinska Institutet

Dept. of Medicine Solna (MedS)

Stockholm, Suecia

2018 - A la fecha


Blue-shift photoconversion of near-infrared fluorescent proteins for labeling and tracking in living cells and organisms Pennacchietti, Francesca; Alvelid, Jonatan; Morales, Rodrigo A.; Damenti, Martina; Ollech, Dirk; Oliinyk, Olena S.; Shcherbakova, Daria M.; Villablanca, Eduardo J.; Verkhusha, Vladislav V.; Testa, Ilaria Article ISI NATURE COMMUNICATIONS (2023)
Low-grade intestinal inflammation two decades after pelvic radiotherapy Devarakonda, Sravani; Thorsell, Annika; Hedenstrom, Per; Rezapour, Azar; Heden, Lisen; Banerjee, Sanghita; Johansson, Malin E. V.; Birchenough, George; Moren, Amelie Toft; Gustavsson, Karin; Skokic, Viktor; Pettersson, Victor L.; Sjoberg, Fei; Kalm, Marie; Al Masri, Mohammad; Ekh, Michaela; Fagman, Henrik; Wolving, Mats; Perkins, Rosie; Morales, Rodrigo A.; Castillo, Francisca; Villablanca, EduardoJ.; Yrlid, Ulf; Bergmark, Karin; Steineck, Gunnar; Bull, Cecilia Article ISI EBIOMEDICINE (2023)
B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healing Frede, Annika; Czarnewski, Paulo; Monasterio, Gustavo; Tripathi, Kumar P.; Bejarano, David A.; Flores, Ricardo O. Ramirez; Sorini, Chiara; Larsson, Ludvig; Luo, Xinxin; Geerlings, Laura; Novella-Rausell, Claudio; Zagami, Chiara; Kuiper, Raoul; Morales, Rodrigo A.; Castillo, Francisca; Hunt, Matthew; Mariano, Livia Lacerda; Hu, Yue O. O.; Engblom, Camilla; Lennon-Dumenil, Ana-Maria; Mittenzwei, Romy; Westendorf, Astrid M.; Hoevelmeyer, Nadine; Lundeberg, Joakim; Saez-Rodriguez, Julio; Schlitzer, Andreas; Das, Srustidhar; Villablanca, Eduardo J. Article ISI IMMUNITY (2022)
Epithelial GPR35 protects from <i>Citrobacter rodentium</i> infection by preserving goblet cells and mucosal barrier integrity Melhem, Hassan; Kaya, Berna; Kaymak, Tanay; Wuggenig, Philipp; Flint, Emilio; Roux, Julien; Oost, Koen C.; Cavelti-Weder, Claudia; Balmer, Maria L.; Walser, Jean-Claude; Morales, Rodrigo A.; Riedel, Christian U.; Liberali, Prisca; Villablanca, Eduardo J.; Niess, Jan Hendrik Article ISI MUCOSAL IMMUNOLOGY (2022)
Interleukin-10 regulates goblet cell numbers through Notch signaling in the developing zebrafish intestine Morales, Rodrigo A.; Rabahi, Soraya; Diaz, Oscar E.; Salloum, Yazan; Kern, Bianca C.; Westling, Mikaela; Luo, Xinxin; Parigi, Sara M.; Monasterio, Gustavo; Das, Srustidhar; Hernandez, Pedro P.; Villablanca, Eduardo J. Article ISI MUCOSAL IMMUNOLOGY (2022)
The spatial transcriptomic landscape of the healing mouse intestine following damage Parigi, Sara M.; Larsson, Ludvig; Das, Srustidhar; Flores, Ricardo O. Ramirez; Frede, Annika; Tripathi, Kumar P.; Diaz, Oscar E.; Selin, Katja; Morales, Rodrigo A.; Luo, Xinxin; Monasterio, Gustavo; Engblom, Camilla; Gagliani, Nicola; Saez-Rodriguez, Julio; Lundeberg, Joakim; Villablanca, Eduardo J. Article ISI NATURE COMMUNICATIONS (2022)
Perfluorooctanesulfonic acid modulates barrier function and systemic T-cell homeostasis during intestinal inflammation Diaz, Oscar E.; Sorini, Chiara; Morales, Rodrigo A.; Luo, Xinxin; Frede, Annika; Krais, Annette M.; Chavez, Myra N.; Wincent, Emma; Das, Srustidhar; Villablanca, Eduardo J. Article ISI DISEASE MODELS & MECHANISMS (2021)
Autophagy Activation in Zebrafish Heart Regeneration Chávez, Myra N.; Morales, Rodrigo A.; López-Crisosto, Camila; Roa, Juan Carlos; Allende, Miguel L.; Lavandero, Sergio Article SCOPUS SCIENTIFIC REPORTS (2020)
Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1<SUP>+</SUP> Macrophages Regulates Intestinal Homeostasis Kaya, Berna; Donas, Cristian; Wuggenig, Philipp; Diaz, Oscar E.; Morales, Rodrigo A.; Melhem, Hassan; Hernandez, Pedro P.; Kaymak, Tanay; Das, Srustidhar; Hruz, Petr; Franc, Yannick; Geier, Florian; Ayata, C. Korcan; Villablanca, Eduardo J.; Niess, Jan Hendrik; Swiss IBD Cohort Investigators Article ISI Cell Reports (2020)
Retinoic acid induced cytokines are selectively modulated by liver X receptor activation in zebrafish Diaz, Oscar E.; Xue, Shuangjia; Luo, Xinxin; Nava, Joel; Appelblom, Anders; Morales, Rodrigo A.; Das, Srustidhar; Villablanca, Eduardo J. Article ISI REPRODUCTIVE TOXICOLOGY (2020)
Cellular Dynamics during Spinal Cord Regeneration in Larval Zebrafish Anguita-Salinas, Consuelo; Sánchez, Mario; Morales, Rodrigo A.; Ceci, María Laura; Rojas-Benítez, Diego; Allende, Miguel L. Article ISI SCOPUS DEVELOPMENTAL NEUROSCIENCE (2019)
Experimental Models of Intestinal Inflammation: Lessons from Mouse and Zebrafish Diaz, Oscar E.; Morales, Rodrigo A.; Das, Srustidhar; Villablanca, Eduardo J.; Hedin, C; Rioux, JD; DAmato, M Article ISI MOLECULAR GENETICS OF INFLAMMATORY BOWEL DISEASE, 2ND EDITION (2019)
Peripheral Macrophages Promote Tissue Regeneration in Zebrafish by Fine-tuning the Inflammatory Response Rodrigo A. Morales, Miguel L. Allende Article Frontiers in Immunology (2019)
CXCL12a/CXCR4b act to retain neutrophils in caudal hematopoietic tissue and to antagonize recruitment to an injury site in zebrafish larva Susana Paredes-Zúñiga, Rodrigo A. Morales; Salomé Muñoz-Sáchez, Carlos Muñoz-Montecinos; Margarita Parada, Karina Tapia; Carlos Rubilar, Miguel L. Allende Article Immunogenetics (2017)
Macrophage Recruitment Contributes to Regeneration of Mechanosensory Hair Cells in the Zebrafish Lateral Line Simón A. Carrillo, Consuelo Anguita-Salinas; Oscar A. Peña, Rodrigo A. Morales; Salomé Muñoz-Sánchez, Carlos Muñoz-Montecinos; Susana Paredes-Zúñiga, Karina Tapia Article Journal of Cellular Biochemistry (2016)
Treatment with Dexamethasone and Monophosphoryl Lipid A removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features Paulina A. García-González, Bárbara Pesce; María Carmen Molina, Miguel Cuchacovic; Milton L. Larrondo, Óscar Neira; Diego F. Catalán, Catharien M. Hilkens; Ranjeny Thomas, Ricardo A. Verdugo Article Frontiers in Immunology (2016)
Alarmin' Immunologists=> IL-33 as a Putative Target for Modulating T Cell-Dependent Responses Tania Gajardo, Rodrigo A. Morales; Francisco Pérez, Claudia Terraza; Luz Yáñez, Karina Pino-Lagos Article Frontiers in Immunology (2015)
Exogenous interleukin-33 targets myeloid-derived suppressor cells and generates periphery-induced Foxp3+ regulatory T cells in skin-transplanted mice Tania Gajardo, Rodrigo A. Morales; Mauricio Campos-Mora, Javier Campos-Acuña Article Immunology (2015)
Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/ MPTP-Lesioned Dopaminergic Neurons Pabla Aguirre, Natalia P. Mena; Carlos M. Carrasco, Yorka Muñoz; Patricio Pérez-Henríquez, Rodrigo A. Morales; Bruce K. Cassels, Carolina Méndez-Gálvez; Olimpo García-Beltrán, Christian González-Billault Article PLoS One (2015)
Neuropilin-1(+) regulatory T cells promote skin allograft survival and modulate effector CD4(+) T cells phenotypic signature Campos-Mora, M; Morales, R. A.; Pérez F.; Gajardo, T; Campos J.; Catalan, D; Aguillon, J.C.; Pino-Lagos, K Article ISI SCOPUS IMMUNOLOGY AND CELL BIOLOGY (2015)
Retinaldehyde dehydrogenase activity is triggered during allograftrejection and it drives Th1/Th17 cytokine production Rodrigo A. Morales, Mauricio Campos-Mora; Tania Gajardo, Francisco Pérez; Javier Campos, Juan C. Aguillón Article Immunobiology (2015)
A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines Garcia-Gonzalez, P; Morales R.; Hoyos L; Maggi, J; Campos J.; Pesce B,; Garate, D; Larrondo M.; González R.; Soto L.; Ramos, V; Tobar, P.; Molina, MC; Pino-Lagos, K; Catalan, D; Aguillón JC Article ISI SCOPUS Journal of Translational Medicine (2013)


Gene networks in vertebrate immune cells PCI (150094) Proyecto 2015-2017 Investigador(a)
Molecular characterization of neutrophils during inflammation and resolution in vivo FONDECYT (1140702) Proyecto 2014-2017 Tesista
Caracterización de los macrófagos del pez cebra en eventos de inflamación por daño tisular PFCHA (21130458) Proyecto 2013-2017 Tesista
Retinoic acid and IL-33=> the dynamic duo controlling the polarization of T cell-mediated immunity FONDECYT (11121309) Proyecto 2012-2015 Personal técnico y/o de apoyo
APPLYING THE KNOWLEDGE ON MURINE TOLEROGENIC DENDRITIC CELLS TO THE DEVELOPMENT OF TOLEROGENIC MONOCYTE-DERIVED DENDRITIC CELLS FROM RHEUMATOID ARTHRITIS (RA) PATIENTS AIMED AT PROVIDING A THERAPEUTIC STRATEGY FOR RA TREATMENT FONDECYT (1100102) Proyecto 2010-2013 Tesista


Neuropilin-1 in transplantation tolerance Campos-Mora, M; Morales, RA; Gajardo, T; Catalan, D; Pino-Lagos, K Review ISI SCOPUS Frontiers in immunology (2013)