Man

Lorena Paz Carvajal Rios

Líneas de Investigación


Autofagia y ox-LDL en el desarrollo placentario

Educación

  •  Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2023

Experiencia Académica

  •   Profesor instructor Other

    Universidad San Sebastián

    Medicina y Ciencia

    Santiago, Chile

    2021 - A la fecha

Experiencia Profesional

  •   Personal técnico de laboratorio Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2016 - 2017


 

Article (13)

The autophagy process and oxidized LDL independently modulate the invasion and differentiation of extravillous trophoblastic cells to an endothelial-like phenotype in normoxia

Escalona, Rodrigo

Article ISI
PLACENTA  (2024)

Trophoblast Cell Recovery from Angiogenesis-Tube Formation Assay for Differentiation Marker Expression Analysis

Gutierrez, Jalme A.

Article ISI
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS  (2024)

Small extracellular vesicles from pregnant women with maternal supraphysiological hypercholesterolemia impair endothelial cell function in vitro

Valdivia, Pascuala; Zapata, David; Cerda, Alvaro

Article ISI
VASCULAR PHARMACOLOGY  (2023)

Autophagy Process in Trophoblast Cells Invasion and Differentiation: Similitude and Differences With Cancer Cells



Article ISI
FRONTIERS IN ONCOLOGY  (2021)

Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia

Kallol S.; Pastén V.; Albrecht C.

Article ISI SCOPUS
Scientific Reports  (2020)

Gestational Diabetes Mellitus Treatment Schemes Modify Maternal Plasma Cholesterol Levels Dependent to Women's Weight: Possible Impact on Feto-Placental Vascular Function



Article ISI SCOPUS
NUTRIENTS  (2020)

Eleveted maternal lipid level increases cholesterol efflux to hdl in human trophoblast but not in placental microvascular endothelial cells

Fuenzalida B., Cantin C.; Carvajal L., Contreras-Duarte S.; Sobrevia L., Leiva A.

Article
Placenta  (2017)

Increased maternal lipid levels reduce the placental HDL and LDL cholesterol uptake in human trophoblast

Cantin C., Carvajal L.; Fuenzalida B., Contraras-Duarte S.; Sobrevia L., Leiva A.

Article
Placenta  (2017)

Maternal supraphysiological dyslipidemia in pregnancy worse vascular response of umbilical vein rings from gestational diabetes mellitus.

Carvajal L., Cantin C.; Fuenzalida B., Contreras-Duarte S.; Sobrevia L., Leiva L.

Article
Placenta  (2017)

Modulation of the placental HDL and LDL cholesterol uptake by the maternal lipids level in human trophoblast

Cantin C., Carvajal L.; Fuenzalida B., Contreras-Duarte S.; Sobrevia L., Leiva A.

Article
Placenta  (2017)

Neonatal high-density lipoprotein from pregnancies with maternal supraphysiological hypercholesterolemia impairs nitric oxide synthase activity in human umbilical vein endothelial cells

Contreras-Duarte S., Fuenzalida B.; Cantin C., Carvajal L.; Sobrevia L., Leiva A.

Article
Placenta  (2017)

Prevalence of maternal supraphysiological dyslipidemia in a group of Chilean pregnant women with gestational diabetes mellitus

Contreras-Duarte S., Carvajal L.; Cantin C., Fuenzalida B.; Sobrevia L., Leiva A.

Article
Placenta  (2017)

Hypotensive and antihypertensive effects of a hydroalcoholic extract from Senecio nutans Sch. Bip. (Compositae) in mice=> Chronotropic and negative inotropic effect, a nifedipine-like action

Fredi Cifuentes, Adrián Paredes; Javier Palacios, Fernanda Muñoz; Lorena Carvajal, Chukwuemeka R. Nwokocha

Article
Journal of ethnopharmacology  (2016)

Abstract (2)

MATERNAL SUPRAPHYSIOLOGICAL DYSLIPIDEMIA INDUCES ARGINASES-INCREASE IMPAIRING FETO-PLACENTAL ENDOTHELIAL FUNCTION IN PREGNANCIES WITH GESTATIONAL DIABETES MELLITUS



Abstract ISI
PLACENTA  (2019)

PREECLAMPSIA IS ASSOCIATED WITH AN IMBALANCE IN THE PROTEIN EXPRESSION OF LDLR AND SR-BI, TOTAL CHOLESTEROL LEVELS AND AUTOPHAGY MARKERS IN THE HUMAN PLACENTA

Morselli E.

Abstract ISI
PLACENTA  (2018)

Proyecto (1)

Involvement of PCSK9 in "human maternal supraphysiological hypercholesterolemia". Effects on placental cholesterol traffic and function of neonatal lipoproteins

FONDECYT (1150344)

Proyecto
2015-2018
Tesista

Review (1)

Maternal Dyslipidaemia in Pregnancy with Gestational Diabetes Mellitus: Possible Impact on Foetoplacental Vascular Function and Lipoproteins in the Neonatal Circulation



Review ISI
CURRENT VASCULAR PHARMACOLOGY  (2019)

1
Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

1
Jaime Gutierrez

Associate Professor and Researcher

Tecnología Médica

Universidad San Sebastián

Santiago, Chile

5
Andrea Leiva

Profesor Asociado

Facultad de Ciencias de la Salud

Universidad San Sebastián

Santiago, Chile

1
Sebastián Illanes

professor, Director of Reproductive Biology Laboratory

Medicine

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

1
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

3
Susana Contreras

Assistant Professor

Nutrition and Dietetics

Universidad San Sebastián

Santiago, Chile

1
ivo carrasco

Investigador

Universidad San Sebastián

Santiago, Chile

1
Mario Subiabre

4
Claudette Cantin

Profesor Asistente

Universidad San Sebastián

Puerto Montt, Chile

9
Lorena Carvajal