Man

MARCO ANTONIO RAMIREZ GALLARDO

Associate Professor

Universidad de Antofagasta

Antofagasta, Chile

Líneas de Investigación


1. Transporte en epitelios 2. Regulación de pH intracelular 3. pH intracelular y patologías asociadas

Educación

  •  BIological Sciences, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1987
  •  Phisyology, UNIVERSIDAD DE CONCEPCION. Chile, 1996
  •  Physiology, UNIVERSIDADE DE SAO PAULO. Chile, 2000

Experiencia Académica

  •   Postdoctor Full Time

    UNIVERSIDADE DE SAO PAULO

    Sao Paulo, Brasil

    2001 - 2002

  •   Postdoctor Full Time

    Hospital Bichat

    Paris, Francia

    2002 - 2003

  •   Associate Professor Full Time

    UNIVERSIDAD DE ANTOFAGASTA

    Antofagasta, Chile

    2004 - A la fecha

Experiencia Profesional

  •   Associate Professor Full Time

    Universidad de Antofagasta

    Antofagasta, Chile

    2004 - A la fecha

  •   Director Full Time

    Universidad de Antofagasta, Facultad de Ciencias de la Salud, Departamento Biomédico

    Antofagasta, Chile

    2010 - 2016

Formación de Capital Humano


2012- AT PRESENT Marcelo Cornejo. PhD Thesis in Biologycal Sciences. Universidad de Antofagasta, Chile. Tutor: MA Ramírez.

2007-2011 Carmen Aravena Molló. Efecto de trióxido de arsénico sobre la proliferación celular vía activación de la
isoforma 1 del intercambiador Na+/H+ (NHE1) en células MDCK. PhD Thesis in Biologycal Sciences. Universidad de Antofagasta, Chile. Tutor: MA Ramírez.

2007-2010 Natalia Celis Bastidas . Efecto de la acidificación intracelular en la captación de adenosina mediante los sistemas de transporte equilibrativos para nucleósidos. MSc Thesis in Biologycal Sciences. Universidad de Antofagasta, Chile. Tutor: MA Ramírez.



 

Article (20)

Arsenic trioxide-increased MDCK cells proliferation requires activator protein 1-mediated increase of the sodium/proton exchanger 1 activity

Cornejo, Marcelo; Mieres-Castro, Daniel; Blanco, Elias H.; Beltran, Ana R.; Araya, Jorge E.; Fuentes, Gonzalo; Figueroa, Manuel; Labarca, Cristian; Toledo, Fernando; Ramirez, Marco A.; Sobrevia, Luis

Article ISI
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2021)

Baroreflex Modulation During Acute High-Altitude Exposure in Rats

Beltran, Ana Rosa; Arce-Alvarez, Alexis; Ramirez-Campillo, Rodrigo; Vasquez-Munoz, Manuel; von Igel, Magdalena; Ramirez, Marco A.; del Rio, Rodrigo; Andrade, David C.

Article ISI
FRONTIERS IN PHYSIOLOGY  (2020)

Involvement of Intracellular pH in Vascular Insulin Resistance

Ramírez, Marco A.; Beltrán, Ana R.; Araya, Jorge E.; Cornejo, Marcelo; Toledo, Fernando; Fuentes, Gonzalo; Sobrevia, Luis

Article ISI SCOPUS
CURRENT VASCULAR PHARMACOLOGY  (2019)

Intracellular acidification reduces L-arginine transport via system y(+)L but not via system y(+)/CATs and nitric oxide synthase activity in human umbilical vein endothelial cells

Ramirez, MA; Morales, J; Cornejo, M; Blanco, EH; Mancilla-Sierpe, E; Toledo, F; Beltran, AR; Sobrevia, L

Article ISI SCOPUS
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2018)

Intracellular acidification increases adenosine transport in human umbilical vein endothelial cells

Celis, Natalia; Araos, Joaquín; Sanhueza, Carlos; Toledo, Fernando; Beltrán, Ana R.; Pardo, Fabián; Leiva, Andrea; Ramírez, Marco A.; Sobrevia, Luis

Article ISI SCOPUS
PLACENTA  (2017)

Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer

Sanhueza, C.; Araos, J.; Naranjo, L.; Toledo, F.; Beltran, A. R.; Ramirez, M. A.; Gutierrez, J.; Pardo, F.; Leiva, A.; Sobrevia, L

Article ISI SCOPUS
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2017)

Modulation of intracellular ph in human ovarian cancer

Sanhueza C.; Araos, J; Naranjo, L.; Villalobos, R; Westermeier, F; Salomon, C; Beltrán A.R.; Ramirez, M. A.; Gutierrez J.; Pardo F.; Leiva A.; Sobrevia L.

Article SCOPUS
Current Molecular Medicine  (2016)

Escherichia coli Heat-Stable Enterotoxin Mediates Na+/H+ Exchanger 4 Inhibition Involving cAMP in T-84 Human Intestinal Epithelial Cells

Beltran, AR; Carraro-Lacroix, LR; Bezerra, CNA; Cornejo M.; Norambuena, K; Toledo, F.; Araos, J; Pardo F.; Leiva A.; Sanhueza C.; Malnic, G; Sobrevia L.; Ramirez, MA

Article ISI SCOPUS
PLOS ONE  (2015)

Insulin restores L-arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia

Salsoso, R; Guzman-Gutierrez, E; Sáez T.; Bugueno, K; Ramirez, M. A.; Farias M.; Pardo F.; Leiva A.; Sanhueza C.; Mate, A; Vazquez, C.; Sobrevia L.

Article ISI SCOPUS
PLACENTA  (2015)

Potential Role of Sodium-Proton Exchangers in the Low Concentration Arsenic Trioxide-Increased Intracellular pH and Cell Proliferation

Aravena, C; Beltrán A.R.; Cornejo M.; Torres V.; Diaz E.S.; Guzman-Gutierrez, E; Pardo F.; Leiva A.; Sobrevia L.; Ramirez, M. A.

Article ISI SCOPUS
PLOS ONE  (2012)

Functional Link Between Adenosine and Insulin: A Hypothesis for Fetoplacental Vascular Endothelial Dysfunction in Gestational Diabetes

Guzman-Gutierrez, E; Abarzua, F; Belmar C.; Nien JK; Ramirez, MA; Arroyo, P; Salomon, C; Westermeier, F; Puebla, C; Leiva A.; Casanello, P; Sobrevia L.

Article ISI SCOPUS
CURRENT VASCULAR PHARMACOLOGY  (2011)

The Laminin-Induced Acrosome Reaction in Human Sperm Is Mediated by Src Kinases and the Proteasome

Tapia, S; Rojas M.; Morales P.; Ramirez, MA; Diaz, ES

Article ISI SCOPUS
Biology of Reproduction  (2011)

NHE1, NHE2, and NHE4 contribute to regulation of cell pH in T84 colon cancer cells

Beltran, AR; Ramirez, MA; Carraro-Lacroix, LR; Hiraki, Y; Reboucas, NA; Malnic, G

Article ISI SCOPUS
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY  (2008)

Increased NHE1 expression is associated with serum deprivation-induced differentiation in immortalized rat proximal tubule cells

Carraro-Lacroix, LR; Ramirez, MA; Zorn, TMT; Reboucas, NA; Malnic, G

Article ISI SCOPUS
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY  (2006)

Factors affecting ammonium uptake by C11 clone of MDCK cells

Tararthuch, AL; Fernandez, R; Ramirez, MA; Malnic, G

Article ISI
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY  (2002)

Spontaneous water secretion in T84 cells: effects of STa enterotoxin, bumetanide, VIP, forskolin, and A-23187

Toriano, R; Kierbel, A; Ramirez, MA; Malnic, G; Parisi, M

Article ISI
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY  (2001)

Control of cell pH in the T84 colon cell line

Ramirez, MA; Toriano, R; Parisi, M; Malnic, G

Article ISI
JOURNAL OF MEMBRANE BIOLOGY  (2000)

Permeation of NH3/NH4+ and cell pH in colonic crypts of the rat

M. Ramirez, R.Fernandez, G. Malnic

Article
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY  (1999)

Hypoxanthine uptake at the fetal side of human placenta proceeds through a nucleobase-preferring carrier and a non-saturable process

Ramirez, M; Acevedo, CG; Rojas, S; Bravo, I

Article ISI
PLACENTA  (1997)

TRANSPORT AND METABOLISM OF ADENOSINE IN THE PERFUSED HUMAN PLACENTA

ACEVEDO, CG; ROJAS, S; RAMIREZ, M; BRAVO, I

Article ISI
PLACENTA  (1995)

Abstract (2)

THE INTRACELLULAR PH IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS FROM GESTATIONAL DIABESITY IS UNALTERED BY INSULIN

Fuentes, G; Valero, P; Cornejo, M; Paublo, M; Lopez, MA; Ramirez, MA; Sobrevia, L

Abstract ISI
PLACENTA  (2019)

Stimulation of Na+/H+ exchanger activity ina colon cell line by arsenic trioxide

Ramirez, MA; Beltran, AR; Flores M.; Malnic, G

Abstract ISI
PLACENTA  (2006)

Review (1)

Fetoplacental Vascular Endothelial Dysfunction as an Early Phenomenon in the Programming of Human Adult Diseases in Subjects Born from Gestational Diabetes Mellitus or Obesity in Pregnancy

Leiva A.; Pardo F.; Ramirez, MA; Farias M.; Casanello, P; Sobrevia L.

Review ISI SCOPUS
Experimental Diabetes Research  (2011)

23
MARCO RAMIREZ

Associate Professor

Universidad de Antofagasta

Antofagasta, Chile

10
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

8
Ana Beltrán

Profesor asociado

Educación

Universidad de Antofagasta

Antofagasta, Chile

7
Andrea Leiva

Profesor Asociado

Facultad de Ciencias de la Salud

Universidad San Sebastián

Santiago, Chile

6
Fabian Pardo

Profesor titular

Escuela de Medicina

Universidad de Valparaiso

San Felipe, Chile

5
MARCELO CORNEJO

Académico

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

2
Enrique Guzman

Profesor Asistente

Bioquímica Clínica e Inmunología

Universidad de Concepción

Concepción, Chile

2
Paola Casanello

Profesor Asociado

División de Obstetricia y Ginecología

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Carlos Salomón

Academic

University of Concepcion

Concepcion, Chile

2
Emilce Diaz

Profesor Asociado

Biomédico

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

1
Carmen Aravena

Acádemico

Universidad de Valparaíso

San Felipe, Chile

1
Jorge Araya

Profesor Asociado

Departamento de Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

1
Rodrigo Del Rio

Assistant Professor

Physiology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

1
David Andrade

Associate Professor

Biomedico

Universidad de Antofagasta

Antofagasta, Chile

1
Jaime Gutierrez

Associate Professor and Researcher

Tecnología Médica

Universidad San Sebastián

Santiago, Chile

1
Tamara Sáez

Postdoctoral fellow

Obstetrics and Gynecology

University of Alberta

Edmonton, Canada

1
Francisco Westermeier

Universidad de Chile

Santiago, Chile

1
Manuel Figueroa

Académico

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

1
Daniel Mieres

Postdoctorante

Instituto de Ciencias Biológicas

Universidad de Talca

Talca, Chile

1
Fernando Abarzua

Assitant researcher

Universidad de La Frontera

Temuco, Chile

1
Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

1
Elías Blanco

Profesor Asistente

Biomédico

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

1
Manuel Vásquez

DIRECTOR DE CENTRO - INVESTIGADOR

FACULTAD MEDICINA Y CIENCIAS DE LA SALUD

Universidad Mayor de Chile

Santiago, Chile

1
Carlos Puebla

Assistant Professor

Universidad de O'Higgins

Santiago, Chile