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Pablo Andrés Sepúlveda Varela

Cardiólogo Intervencionista

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Interventional cardiology; Clinical cardiology; Clinical trials; Acute coronary syndromes; Pulmonary hypertension; Pulmonary embolism; Heart failure; Cardiovascular molecular biology; Genetic Polymorphism.

Educación

  •  MEDICO CIRUJANO, UNIVERSIDAD DE CHILE. Chile, 1996
  •  MEDICINA INTERNA, UNIVERSIDAD DE CHILE. Chile, 1999
  •  CARDIOLOGIA, Hospital San Juan de Dios. Chile, 2000
  •  CARDIOLOGIA INTERVENCIONAL, Clinique Saint Jean. Bélgica, 2001

Experiencia Académica

  •   PROFESOR AUXILIAR Part Time

    UNIVERSIDAD DE LOS ANDES

    MEDICINA

    Santiago, Chile

    2006 - 2008

  •   PROFESOR ASISTENTE Part Time

    UNIVERSIDAD DE CHILE

    MEDICINA

    Santiago, Chile

    2015 - 2018

  •   PROFESOR ASISTENTE Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    MEDICINA

    Santiago, Chile

    2018 - A la fecha

Experiencia Profesional

  •   Interventional Cardiologist / Head PAH Clinic Part Time

    Hospital San Juan de Dios

    Santiago, Chile

    2001 - 2018

  •   CCU Resident / Interventional Cardiologist Part Time

    Clínica Dávila

    Santiago, Chile

    2001 - 2007

  •   Chief CCU / Interventional Cardiologist Part Time

    Clínica Tabancura

    Santiago, Chile

    2007 - 2016

  •   Interventional Cardiologist Other

    Clínica Las Condes

    Santiago, Chile

    2016 - 2018


 

Article (27)

Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension A Double-Blind Placebo-controlled Clinical Trial

Wang K.Y.; Grünig E.; Hiremath S.; Yip W.L.J.; Svetliza G.N.; Lescano A.J.; Bortman G.R.; Diez F.A.; Botta C.E.; Feenstra E.; et al.

Article ISI SCOPUS
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE  (2020)

Combination therapy with oral treprostinil for pulmonary arterial hypertension. A double-blind placebo-controlled clinical trial.

White, R James; Bohns Meyer, Gisela Martina

Article
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE  (2020)

Balloon pulmonary angioplasty for the treatment of chronic thromboembolic pulmonary hypertension

Juan Ortega; Christian Backhouse; Augusto Bellet; Diego Godoy; Mario Araya; Carmen Luz Andrade; Juan Pablo Molina; Carolina Nazzal

Article ISI SCIELO SCOPUS
REVISTA MEDICA DE CHILE  (2019)

Reperfusión fármaco-invasiva en el manejo del infarto agudo del miocardio en Chile: Un llamado a la acción.



Article
REVISTA CHILENA DE CARDIOLOGIA  (2019)

TREATMENT BENEFITS ASSOCIATED WITH OPEN LABEL ORAL TREPROSTINIL AFTER CLINICAL WORSENING IN THE PHASE 3 FREEDOM-EV STUDY FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION

Grünig, Ekkehard; Jerjes-Sanchez, Carlos; Meyer, Gisela; Pulido, Tomás; SEPULVEDA, PABO; Wang, Kuo; Deng, Chunqin; Grover, Rob; Ousmanou, Aliou; Solum, Derek; et al.

Article
Chest  (2019)

Exceso de mortalidad no cardíaca en pacientes sometidos a angioplastía de puentes coronarios

Hameau, René

Article
REVISTA CHILENA DE CARDIOLOGIA  (2018)

Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial

Lanas, Fernando; Metsarinne, Kaj; Dans, Anthony L.; Parkhomenko, Alexandr N.; Liu Lisheng; Torp-Pedersen, Christian; Widimsky, Petr; Felix, Camilo; Hori, Masatsugu; Guzik, Tomasz J.; et al.

Article ISI
LANCET  (2018)

Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial

Aboyans, Victor; COMPASS Investigators

Article ISI
LANCET  (2018)

Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension

Sitges, Marta; Kanacri, Andrés

Article ISI SCOPUS
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES  (2017)

Characteristics, management, and outcomes of illicit drug consumers with acute myocardial infarction

Bartolucci J.; Nazzal C.; Verdugo, FJ; Prieto, JC; Sepulveda P.; Corbalan, R

Article ISI
REVISTA MEDICA DE CHILE  (2016)

Effect of educational level on the prognosis of acute myocardial infarction

Nazzal C.; Corbalan, R; Diaz, C.; Sepulveda P.; Schacht, E.

Article ISI
REVISTA MEDICA DE CHILE  (2015)

Effect of educational level on the prognosis of acute myocardial infarction [Efecto del nivel educacional en la sobrevida posterior a un infarto agudo de miocardio: Registro Chileno de Infarto de Miocardio, GEMI 2009-2012]

Nazzal C.; Corbalan, R; Diaz, C.; Sepulveda P.; Schacht, E.

Article SCOPUS
Revista Medica de Chile  (2015)

Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome

Pfeffer, Marc A.; Claggett, Brian; Dickstein, Kenneth; Kober, Lars V.; Lawson, Francesca C.; Ping, Lin; Wei, Xiaodan; Lewis, Eldrin F.; McMurray, John J. V.; Probstfield, Jeffrey L.; et al.

Article ISI
NEW ENGLAND JOURNAL OF MEDICINE  (2015)

Prevalence of seven cardiovascular-related genetic polymorphisms in a Chilean mestizo healthy population

Roco, A; Quinones, LA; Sepulveda P.; Donoso, H; Lapostol, C; Alarcon, R; Torres, ME; Veliz, PC; Acuna, G.; Wilke, O; et al.

Article ISI SCOPUS
Acta Cardiologica  (2015)

Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo

Bentley-Lewis R.; Aguilar D; Riddle M.C.; Claggett B.; Diaz R.; Dickstein K.; Johnston P.; Køber L.V.; Lawson F.; Lewis E.F.; et al.

Article ISI SCOPUS
American Heart Journal  (2015)

Effects of Trimetazidine in Nonischemic Heart Failure: A Randomized Study

Winter, José Luis; Castro Pablo F.,; Quintana, Juan Carlos; Altamirano, Rodrigo; Enriquez, Andres; Verdejo Hugo E.; Jalil, Jorge E.; Mellado, Rosemarie; Concepción, Roberto; Sepulveda, Pablo; et al.

Article ISI
JOURNAL OF CARDIAC FAILURE  (2014)

Alogliptin after Acute Coronary Syndrome in Patients with Type 2 Diabetes

White, William B.; Cannon, Christopher P.; Heller, Simon R.; Nissen, Steven E.; Bergenstal, Richard M.; Bakris, George L.; Perez, Alfonso T.; Fleck, Penny R.; Mehta, Cyrus R.; Kupfer, Stuart; et al.

Article ISI
NEW ENGLAND JOURNAL OF MEDICINE  (2013)

Prasugrel versus Clopidogrel for Acute Coronary Syndromes without Revascularization

Roe, M. T.; Fox K.A.A.; White, H. D.; Prabhakaran D.; Goodman, S. G.; Bhatt, D. L.; Clemmensen P.; Martinez F.; Ardissino, D; Boden W.E.; et al.

Article ISI SCOPUS
New England Journal of Medicine  (2012)

Relationship between mechanical and metabolic dyssynchrony with left bundle branch block: Evaluation by 18-fluorodeoxyglucose positron emission tomography in patients with non-ischemic heart failure

Castro P. ; Verdejo H.; Orellana, P; greig d.; Enriquez A.; Sepulveda, L; Concepcion, R; Sepulveda P.; Rossel V.; Chiong M.; et al.

Article ISI SCOPUS
Journal of Heart and Lung Transplantation  (2012)

Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes

Tricoci, P.; Huang Z.; Held, C; Van de Werf, F; White, H. D.; Wallentin L.; Chen E.; Lokhnygina, Y; Pei, J; Leonardi S.; et al.

Article ISI SCOPUS
New England Journal of Medicine  (2012)

Cambios en el pronóstico a largo plazo de la hipertensión arterial pulmonar

Enriquez, Andres; Castro, Pablo; Sepulveda, Pablo; Verdejo, Hugo; Greig, Douglas; Gabrielli, Luigi; Ferrada, Marcela; Lapostol, Carolina

Article SCIELO SCOPUS
REVISTA MEDICA DE CHILE  (2011)

Changes long term prognosis of 17 patients with pulmonary artery hypertension

Enriquez A.; Castro P. ; Sepulveda P.; Verdejo H.; greig d.; Gabrielli, L; Ferrada M.; Lapostol, C

Article ISI
REVISTA MEDICA DE CHILE  (2011)

Chilean results of the international registry of risk factors and treatment of unstable angina and non ST elevation myocardial infarction: ACCORD (ACute CORonary syndrome Descriptive study)

STOCKINS B.; Albornoz F; Martínez, D.; Campos P.; Gajardo, J; Lamich R.; Manriquez, L; Perez, V.; Rojo, P; Sepulveda P.; et al.

Article ISI
REVISTA MEDICA DE CHILE  (2011)

Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)

Stockins, Benjamín; Albornoz, Francisco; MARTÍNEZ, DARÍO; CAMPOS, PABLA; Gajardo, Jorge; Lamich, Rubén; Manríquez, Leopoldo; Pérez, Víctor; Rojo, Pamela; Sepulveda, Pablo; et al.

Article SCIELO SCOPUS
REVISTA MEDICA DE CHILE  (2011)

Valvuloplastía mitral percutánea: experiencia del Hospital San Juan de Dios

Dighero, Humberto; Zepeda, Flavio; Soto, Marcelo; Godoy, Diego; Puentes, Ángel; Aranda Waldo; Mori, Gorky; Sepulveda, Pablo; Dighero, Bruno

Article SCIELO
REVISTA CHILENA DE CARDIOLOGIA  (2010)

Percutaneous mitral balloon valvotomy: Six-year follow-up

Dighero, H; Zepeda, F; Sepulveda P.; Aranda W.

Article SCOPUS
JOURNAL OF INVASIVE CARDIOLOGY  (2001)

Características clínicas y tratamiento de pacientes con infarto agudodel miocardio con supradesnivel st y shock cardiogénico: 9 años del Registro GEMI

Prieto, JC; Schacht, ME.; Bartolucci J.

Article
REVISTA CHILENA DE CARDIOLOGIA  

Abstract (8)

Dose-response relationship of oral treprostinil for secondary endpoints in the FREEDOM-EV study

White, RJ

Abstract ISI
EUROPEAN RESPIRATORY JOURNAL  (2019)

Treatment with Oral Treprostinil Delays Time to Clinical Worsening in Patients with Pulmonary Arterial Hypertension - Results from FREEDOM-EV

Tapson, VF; Diaz, CJS; Meyer, GMB; Pulido, T; Deng, CQ; Grover, R; Solum, D; Ousmanou, A; White, RJ

Abstract ISI
JOURNAL OF HEART AND LUNG TRANSPLANTATION  (2019)

Acute changes in right atrial function after iloprost inhalation in patients with pulmonary arterial hypertension: an echocardiographic deformation imaging study

Gabrielli, L; Kanacri, A; Vega, J; Saavedra, R; Cordova, S; Sepulveda P.; Castro P.

Abstract ISI
EUROPEAN HEART JOURNAL  (2015)

Acute changes in right ventricular synchrony and function post inhaled iloprost in pulmonary artery hypertension patients: a myocardial deformation imaging study

Gabrielli, L; Saavedra, R; Cordova, S; Llevaneras, S; Sepulveda P.; Castro P.

Abstract ISI
EUROPEAN HEART JOURNAL  (2014)

Long term survival after acute myocardial infarction according to attained education level in the Chilean AMI Register, GEMI 2009-2012

Nazzal C.; Corbalan, R; Sepulveda P.; Diaz, C.; Schacht, E.

Abstract ISI
EUROPEAN HEART JOURNAL  (2014)

Differences in treatment and in-hospital mortality of acute myocardial infarction patients in public and private hospitals in Chile before and after healthcare guarantees

Nazzal C.; Corbalan, R; Frenz, P; Sepulveda P.; Prieto, J.

Abstract ISI
EUROPEAN HEART JOURNAL  (2013)

Increased Oxidative Stress Correlates With Pulmonary Vascular Response to Vasodilators in Pulmonary Artery Hypertension Patients

Castro P. ; Gabrielli, L; Fasce, F; Verdejo H.; greig d.; Llevaneras, S; Ferrada M.; Hernandez, C; Godoy, I; García, L.; et al.

Abstract ISI
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY  (2009)

Ambulatory radial coronary angioplasty: Is it a feasible approach?

Dighero, H; Fuentes A.; Zepeda, F; Donoso, H; Belief, A; Sepulveda P.; Dighero, B; Wolff, C

Abstract ISI
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY  (2008)

BookSection (2)

Tromboembolismo Pulmonar



BookSection
 (2019)

Paro Cardiorespiratorio



BookSection
 

1
Juan Carlos Quintana

Médico nuclear

Radiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Fernando Lanas

Profesor titular

Medicina Interna

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

1
JORGE JALIL

FULL PROFESSOR

ENFS CARDIOVASCULARES

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, ESCUELA DE MEDICINA

Santiago, Chile

3
SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

3
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

1
Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Luis Quinones

PROFESOR TITULAR

ONCOLOGIA BASICO-CLINICA

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Rosemarie Mellado

Jefe de carrera / Académica

Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Juan Prieto

Profesor Titular

Programa de Farmacología Molecular y Clínica

Universidad de Chile

Santiago, Chile

4
Ramon Corbalan

Director

Division of Cardiovascular Diseases

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

37
Pablo Sepúlveda

Cardiólogo Intervencionista

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Luigi Gabrielli

Profesor Asistente

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

1
Laura Huidobro

Académico

Ciencias Preclínicas

Universidad Católica del Maule

Talca, Chile

5
Carolina Nazzal

Profesor Asociado

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

1
Maria Ocaranza

Full Professor

Cardiovascular Diseases Division

Pontificia Universidad Catolica de Chile

Santiago, Chile

4
Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

4
Douglas Greig

Médico Jefe

Cardiología

P. Universidad Católica de Chile

Santiago, Chile

1
Angel Puentes

Jefe

Servicio de Cardiología

Hospital San Juan de Dios

Santiago, Chile

1
Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

1
Fernando Verdugo

Cardiologo

Cardiologia

Hospital del Salvador

Santiago, Chile

1
MONICA ZAGOLIN

COORDINADOR PROGRAMA

DOCENCIA Y MEDICINA

INSTITUTO DEL TORAX

santiago, Chile

3
Victor Rossel

Profesor Asociado (D)

Medicina Interna Oriente

Universidad de Chile

SANTIAGO, Chile