Man

Mauricio Gabriel Henriquez Luna

Profesor asistente

Universidad de Chile / Facultad de Medicina

Santiago, Chile

Líneas de Investigación


Rol de los Receptores Purinérgicos en el control de tono de vasos pulmonares y bronquiolos, particularmente su participación en Hipertensión Arterial pulmonar, Síndrome de Distrés Respiratorio y últimamente en Enfermedad Pulmonar Obstructiva Crónica.

Educación

  •  TECNOLOGO MEDICO, UNIVERSIDAD DE CHILE. Chile, 1995
  •  BIOLOGÍA DE LA REPRODUCCIÓN, UNIVERSIDAD DE CHILE. Chile, 2001
  •  CIENCIAS BIOMÉDICAS, UNIVERSIDAD DE CHILE. Chile, 2005

Experiencia Académica

  •   PROFESOR ASISTENTE Full Time

    UNIVERSIDAD DE CHILE

    MEDICINA

    SANTIAGO, Chile

    2009 - A la fecha

  •   Research Associate Full Time

    TEXAS TECH UNIVERSITY

    HEALTH SCIENCES CENTER

    Lubbock, Tx, Estados Unidos

    2010 - 2011

  •   Postdoctoral Fellow Full Time

    UNIVERSIDAD DE CHILE

    MEDICINA

    SANTIAGO, Chile

    2006 - 2008

  •   Research Assistant Part Time

    UNIVERSIDAD DE CHILE

    MEDICINA

    SANTIAGO, Chile

    1997 - 2005

Experiencia Profesional

  •   Profesor asistente Full Time

    Universidad de Chile / Facultad de Medicina

    Santiago, Chile

    2009 - A la fecha

  •   Tecnólogo Médico Full Time

    Universidad de Chile / Hospital José Joaquín Aguirre

    Santiago, Chile

    1994 - 1997

  •   Asistente de Investigación Part Time

    Universidad de Chile / Instituto de Ciencias Biomédicas / Programa de Fisiología y Biofísica

    Santiago, Chile

    1997 - 2005


 

Article (19)

Primary infection by Pneumocystis induces Notch-independent Clara cell mucin production in rat distal airways
Cancer Imprints an Increased PARP-1 and p53-Dependent Resistance to Oxidative Stress on Lymphocytes of Patients That Later Develop Alzheimer's Disease.
Purinergic receptor stimulation induces calcium oscillations and smooth muscle contraction in small pulmonary veins.
Vitamin D Increases A beta 140 Plasma Levels and Protects Lymphocytes from Oxidative Death in Mild Cognitive Impairment Patients
PARP-1 and p53 Regulate the Increased Susceptibility to Oxidative Death of Lymphocytes from MCI and AD Patients
Increased Susceptibility to Oxidative Death of Lymphocytes from Alzheimer Patients Correlates with Dementia Severity
FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X(7)
Age-Dependent Increases in Apoptosis/Necrosis Ratios in Human Lymphocytes Exposed to Oxidative Stress
ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation
Electrophysiological Characterization of Potassium Conductive Pathways in Trypanosoma cruzi
Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells
Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane
Puroindoline-a and alpha 1-purothionin form ion channels in giant liposomes but exert different toxic actions on murine cells
Proteomic analysis of apical microvillous membranes of syncytiotrophoblast cells reveals a high degree of similarity with lipid rafts.
Isolation and purification of human placental plasma membranes from normal and pre-eclamptic pregnancies. A comparative study
Neuronal and muscular alterations caused by two wheat endosperm proteins, puroindoline-a and alpha1-purothionin, are due to ion pore formation
17 beta-estradiol and tamoxifen regulate a maxi-chloride channel from human placenta
A low conductance, non-selective cation channel from human placenta
Functional transplantation of chloride channels from the human syncytiotrophoblast microvillous membrane to Xenopus oocytes

Abstract (10)

Purinergic receptor stimulation induces Ca2+ oscillations and smooth muscle contraction in small pulmonary veins
Comparative total currents between apical syncytiotrophoblast membrane in normal and pre-eclamptic human placenta transplanted to Xenopus laevis oocytes.
Detergent-resistant membrane microdomains in apical membranes from human syncytiotrophoblast
Maxi Chloride Channel is a candidate for apical ATP release in human placental syncytiotrophoblast
VDAC-1 as the molecular correlate of the maxi chloride channel from human placental syncytiotrophoblast
Proteomic analysis of apical microvillous membranes of syncitiothrophoblast cells reveals a high degree of similarity with lipid rafts
Regulation of human placental chloride channel by steroids hormones
Non selective cation channels from human placenta.
Non-selective cation channel in placental membranes
Transplantation of chloride channels from human placenta to the membrane of Xenopus oocytes

BookSection (1)

La puroindoline-a et l'alfa-1-purothionine: deux protéines de l’albumen de blé formatrices de pores ioniques

Proyecto (7)

Red para el Estudio de Enfermedades Cardiopulmonares de Alta Letalidad (REECPAL)
"Nueva terapia farmacológica para el tratamiento de sarcopenia y distrofias musculares. Prueba de concepto"
Determinants of lung injury induced by spontaneous breathing efforts during the transition from controlled ventilation to partial ventilatory support in ARDS patients
CELLULAR SENESCENCE AND SENESCENCE-ASSOCIATED SECRETION PHENOTYPE (SASP) INVOLVEMENT IN THE INVERSE ASSOCIATION BETWEEN ALZHEIMER DISEASE AND CANCER
SMALL INTRAPULMONARY VESSELS IN PULMONARY HYPERTENSION=> PURINERGIC CONTROL OF PULMONARY VASCULAR TONE
Nuevas alternativas en el efecto de TRH en la maduración pulmonar fetal
Automatización de una técnica de TSH neonatal para el diagnóstico precoz de hipotiroidismo congénitol

Review (1)

Cell death by necrosis, a regulated way to go
28
Mauricio Henriquez

Profesor asistente

PROGRAMA DE FISIOLOGÍA Y BIOFíSICA

Universidad de Chile / Facultad de Medicina

Santiago, Chile

6
Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

4
Felipe Salech

Academic

Medicine

Universidad de Chile / Facultad de Medicina

Santiago, Chile

4
Maria Behrens

Profesor Titular

Neurología y Neurocirugía, y de Neurociencia

Hospital Clínico Universidad de Chile

Santiago, Chile

4
Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

2
Mónica Silva

Lab Manager

Fisiología y Biofísica

Universidad de Chile

Santiago, Chile

2
JUAN VILLENA

ASSOCIATE PROFESSOR

BIOMEDICAL SICIENCES

FACULTA DE MEDICINA. UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

2
Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

2
Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

2
Nicole Rogers

Instructora

Universidad de Chile

Santiago, Chile

2
Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

1
Patricia Diaz

Academic

University of Connecticut Health Center

Farmington, CT, Estados Unidos

1
Rodrigo Herrera

Group Leader (staff member)

Combinatorial NeuroImaging Core Facility

Leibniz Institute for Neurobiology

Magdeburg, Alemania

1
Veronica Eisner

Associate Professor

Cellular and Molecular Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Jorge Toledo

Investigador

Departamento de Anatomia y Biologia del Desarrollo

Universidad de Chile; Biomedical Neuroscience Institute (BNI)

Santiago, Chile

1
Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Paula Díaz

-

-

-, Chile

1
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

1
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

1
Daniela Ponce

Coordinadora de investigación

Universidad de Chile

Santiago, Chile

1
claudio olea

Full Professor

Inorganica y Analitica

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Carolina Ponce

Lab Manager Lab Infecciones Rspiratorias

Microbiología Y MIcología

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Sergio Lavandero

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Andrea Méndez

Académico Disciplinar Investigador

Facultad de Ciencias de la Salud

Universidad de Las Américas

Santiago, Chile

1
Caroll Beltrán

Profesor Asistente, Investigador Principal

Medicina

Universidad de Chile, Fac Medicina

SANTIAGO, Chile

1
Diego Rojas

Académico

ICB

Universidad Autónoma de Chile

Santiago, Chile

1
Sergio Vargas

Investigador Académico

Universidad de Chile

Santiago, Chile

1
Hachi Manzur

Neurólogo de Adultos

Red de Salud UC Christus

Santiago, Chile

1
Valeria Godoy

Jefa subrogante

Centro Nacional de Conservación y Restauración

Santiago, Chile