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Diego Andrés Rojas Soto

Académico

Universidad Autónoma de Chile

Santiago, Chile

Transcripción en Eucariontes; Complejos transcripciones; infecciones respiratorias por hongos (Pneumocystis); COPD.

Biólogo Molecular, Microbiólogo, UNIVERSIDAD DE CHILE. Chile, 2012
Ingeniero en Biotecnología Molecular, UNIVERSIDAD DE CHILE. Chile, 2009

Profesor Ayudante Other

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2010 - 2019
Académico Full Time

Universidad Autónoma de Chile

Ciencias de la Salud

Santiago, Chile

2020 - A la fecha

Investigador Part Time

Bioingentech

Santiago, Chile

2018 - 2018
Investigador Postdoctoral Full Time

Universidad de Santiago

Santiago, Chile

2019 - 2020
Investigador Postdoctoral Full Time

Universidad de Chile

Chile

2013 - 2018


Increase in secreted airway mucins and partial Muc5b STAT6/FoxA2 regulation during Pneumocystis primary infection. Rojas, Diego A; Iturra, Pablo A; Méndez, Andrea; Ponce, Carolina A; Bustamante, Rebeca; Gallo, Miriam; Bórquez, Pamela; Vargas, Sergio L Article Scientific reports (2019)
Primary infection by Pneumocystis induces Notch-independent Clara cell mucin production in rat distal airways Mendez, Andrea; Rojas, Diego A.; Ponce, Carolina A; Bustamante, Rebeca; Beltran, Carol J.; Toledo, Jorge; Garcia-Angulo, Victor A.; Henriquez, Mauricio; Vargas, Sergio L. Article ISI SCOPUS PLOS ONE (2019)
Endogenous overexpression of an active phosphorylated form of DNA polymerase Î² under oxidative stress in Trypanosoma cruzi. Rojas, Diego A; Urbina, Fabiola; Moreira-Ramos, Sandra; Castillo, Christian; Kemmerling, Ulrike; Lapier, Michel; Maya, Juan Diego; Solari, Aldo; Maldonado, Edio Article PLoS neglected tropical diseases (2018)
Progression of Type 2 Helper T Cell-Type Inflammation and Airway Remodeling in a Rodent Model of Naturally Acquired Subclinical Primary Pneumocystis Infection. Iturra, Pablo A; Rojas, Diego A; Pérez, Francisco J; Méndez, Andrea; Ponce, Carolina A; Bonilla, Paula; Bustamante, Rebeca; Rodríguez, Héctor; Beltrán, Caroll J; Vargas, Sergio L Article The American journal of pathology (2018)
RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe. Montes, Matías; Moreira-Ramos, Sandra; Rojas, Diego A; Urbina, Fabiola; Käufer, Norbert F; Maldonado, Edio Article The FEBS journal (2017)
The Ski Protein is Involved in the Transformation Pathway of Aurora Kinase A Rivas S., Armisen R; Rojas DA, Maldonado E; Huerta H., Tapia JC; Espinoza J, Colombo A.; Michea L, Hayman; MJ, Marcelain K Article Journal of Cellular Biochemistry (2016)
Casein kinase 2 inhibits HomolD-directed transcription by Rrn7 in Schizosaccharomyces pombe. Moreira-Ramos, Sandra; Rojas, Diego A; Montes, Matías; Urbina, Fabiola; Miralles, Vicente J; Maldonado, Edio Article The FEBS journal (2015)
Expression, purification, and biochemical characterization of recombinant DNA polymerase beta of the Trypanosoma cruzi TcI lineage=> requirement of additional factors and detection of phosphorylation of the native form. Maldonado, Edio; Rojas, Diego A; Moreira-Ramos, Sandra; Urbina, Fabiola; Miralles, Vicente J; Solari, Aldo; Venegas, Juan Article Parasitology research (2015)
Fungal colonization with Pneumocystis correlates to increasing chloride channel accessory 1 (hCLCA1) suggesting a pathway for up-regulation of airway mucus responses, in infant lungs. Pérez, Francisco J; Ponce, Carolina A; Rojas, Diego A; Iturra, Pablo A; Bustamante, Rebeca I; Gallo, Myriam; Hananias, Karime; Vargas, Sergio L Article Results in immunology (2014)
Transcription directed by human core promoters with a HomolD box sequence requires DDB1, RECQL and RNA polymerase II machinery. Contreras-Levicoy, Juan; Moreira-Ramos, Sandra; Rojas, Diego A; Urbina, Fabiola; Maldonado, Edio Article Gene (2012)
Identification of Ski as a target for Aurora A kinase Mosquera J, Armisen R; Zhao, HL; Rojas DA, Maldonado E; Tapia JC, Colombo A.; Hayman, MJ Article Biochemical and Biophysical Research Communications (2011)
Rrn7 protein, an RNA polymerase I transcription factor, is required for RNA polymerase II-dependent transcription directed by core promoters with a HomolD box sequence. Rojas, Diego A; Moreira-Ramos, Sandra; Zock-Emmenthal, Susanne; Urbina, Fabiola; Contreras-Levicoy, Juan; Käufer, Norbert F; Maldonado, Edio Article The Journal of biological chemistry (2011)
Cloning of hif-1 alpha and hif-2 alpha and mRNA expression pattern during development in zebrafish Rojas DA, Perez-Munizaga; DA, Centanin; L, Antonelli M; Wappner, P; Allende, ML Article Gene Expression Patterns (2007)


Transcriptional Initiation in Ribosomal Protein Genes in the Fission Yeast Schizosaccharomyces pombe Rojas, DA; Moreira-Ramos, S; Urbina F.; Maldonado E. BookSection (2018)

Diego Rojas

Académico

ICB

Universidad Autónoma de Chile

Santiago, Chile

Caroll Beltrán

Profesor Asistente, Investigador Principal

Medicina

Universidad de Chile, Fac Medicina

SANTIAGO, Chile

Jorge Toledo

Investigador

Departamento de Anatomia y Biologia del Desarrollo

Universidad de Chile; Biomedical Neuroscience Institute (BNI)

Santiago, Chile

Sergio Vargas

Investigador Académico

Universidad de Chile

Santiago, Chile

Andrea Méndez

Académico Disciplinar Investigador

Facultad de Salud y Ciencias Sociales

Universidad de Las Américas

Santiago, Chile

Mauricio Henriquez

Profesor asistente

PROGRAMA DE FISIOLOGÍA Y BIOFíSICA

Universidad de Chile / Facultad de Medicina

Santiago, Chile

Carolina Ponce

Lab Manager Lab Infecciones Rspiratorias

Microbiología Y MIcología

UNIVERSIDAD DE CHILE

Santiago, Chile

Diego Andrés Rojas Soto

Líneas de Investigación

Educación

Biólogo Molecular, Microbiólogo, UNIVERSIDAD DE CHILE. Chile, 2012

Ingeniero en Biotecnología Molecular, UNIVERSIDAD DE CHILE. Chile, 2009

Experiencia Académica

Profesor Ayudante Other

Académico Full Time

Experiencia Profesional

Investigador Part Time

Investigador Postdoctoral Full Time

Investigador Postdoctoral Full Time

Article (13)

Increase in secreted airway mucins and partial Muc5b STAT6/FoxA2 regulation during Pneumocystis primary infection.

Primary infection by Pneumocystis induces Notch-independent Clara cell mucin production in rat distal airways

Endogenous overexpression of an active phosphorylated form of DNA polymerase Î² under oxidative stress in Trypanosoma cruzi.

Progression of Type 2 Helper T Cell-Type Inflammation and Airway Remodeling in a Rodent Model of Naturally Acquired Subclinical Primary Pneumocystis Infection.

RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe.

The Ski Protein is Involved in the Transformation Pathway of Aurora Kinase A

Casein kinase 2 inhibits HomolD-directed transcription by Rrn7 in Schizosaccharomyces pombe.

Expression, purification, and biochemical characterization of recombinant DNA polymerase beta of the Trypanosoma cruzi TcI lineage=> requirement of additional factors and detection of phosphorylation of the native form.

Fungal colonization with Pneumocystis correlates to increasing chloride channel accessory 1 (hCLCA1) suggesting a pathway for up-regulation of airway mucus responses, in infant lungs.

Transcription directed by human core promoters with a HomolD box sequence requires DDB1, RECQL and RNA polymerase II machinery.

Identification of Ski as a target for Aurora A kinase

Rrn7 protein, an RNA polymerase I transcription factor, is required for RNA polymerase II-dependent transcription directed by core promoters with a HomolD box sequence.

Cloning of hif-1 alpha and hif-2 alpha and mRNA expression pattern during development in zebrafish

BookSection (1)

Transcriptional Initiation in Ribosomal Protein Genes in the Fission Yeast Schizosaccharomyces pombe

Diego Rojas

Caroll Beltrán

Jorge Toledo

Sergio Vargas

Andrea Méndez

Mauricio Henriquez

Carolina Ponce