PDI - Resultado de Búsqueda

Jimena Alejandra Sierralta Jara

Full Professor

Faculty of Medicine, Universidad de Chile

Santiago, Chile

Research lines, A Scaffold proteins in synaptic function and plasticity. B Genes involved in neuronal morphogenesis C Neuronal-Glia energetic relationship D Blood-Brain barrier. Collaborations LF Barros; Maldonado PE; Olguín P; Oliva C,

biochemistry, Pontificia Universidad Católica de Chile. Chile, 1988
Sciences, BIology, UNIVERSIDAD DE CHILE. Chile, 1996
Biochemist, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1988

Associate Professor Full Time

UNIVERSIDAD DE CHILE

Faculty of Medicine

Santiago, Chile

2004 - A la fecha
Assistant Professor Full Time

UNIVERSIDAD DE CHILE

Faculty of Medicine

Santiago, Chile

1998 - 2004
Full Professor Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2017 - A la fecha

Full Professor Full Time

Universidad de Chile

Santiago, Chile

1998 - A la fecha

Undergraduate thesis
Mrs Gabriela Lafferte (2001), Biochemistry thesis, Universidad de Chile; Mrs. Ximena Martínez, Veterinary thesis (2001), Universidad de Chile; Mrs. Mirna Cruz Engineer in Biotechnology thesis (2003), Universidad de Chile; Mrs. Romina Barría, Biochemistry thesis(2004), Mrs Valeria Albornoz (2004), Biochemistry thesis, Mr. Francisco Urra, Biochemistry thesis, (2005) Mr. Pablo Majóo, Biochemistry thesis (2006), Mr. Gabriel Pavez Biochemistry thesis (2014), Mrs Gabriela Insunza Veterinary thesis (2008), Hector Pacheco, Veterinary thesis (2009). Mr Orlando Chávez (2009) Informatic Engineer, Universidad de Talca, Mrs Pía Escobedo (2010), Biochemistry thesis Faculty of Sciences, Pontificia Universidad Católica de Valparaíso, Mauricio Ramírez (2011) Biology, Pontificia Universidad Católica de Valparaíso, Guillermo Moya (2012), Biochemistry thesis Universidad de Santiago, Diego Villegas, P.Universidad Católica de Chile, (2019) Biochemistry thesis

Graduate thesis
Carolina Mendoza PhD (2003-2006), Carlos Oliva PhD thesis (2007-2010), César Astorga Ph.D. thesis (2010-2014), José Cánovas, Co-advisor Ph.D. thesis (2009-2014), MGraciela Delgado Ph.D. thesis (2012-1015), Cristian de Gregorio, Co-advisor PhD Thesis (2012-2015) Francisca Bertín PhD Thesis (2017-2020), Javiera Gallardo (2018-2020) co-advisor, Andrés Kohler (2018-2021). Ximena Martínez Ms Thesis (2007-2008), Claudia Molina Ms Thesis (2009-2010), Giovanna Otarola Ms Thesis (2009-2010), Ignacio Herrera co-advisor MsThesis in Neuroscience (2014-2015), Francisca Bertín (2014-2015) MsThesis in Neuroscience.Andrés Ibacahe (2017-2018) Ms thesis in genetics.

Current PhD students: Aline Ovalle, co advisor; Andrés Ibacache, co-advisor.
Current Ms students: Liliana Spindola Ms in Neuroscience
Current Undergraduate: Rocío Verdugo , Diego Manque

Postdocs
Dr. Alvaro Glavic (2005-2006)
Dr. Diego Rojas (2013-2015)
Dr. Carlos Oliva (2014-2016)
Dr. Esteban Contreras (2015-2019)
Dr. Andrés González (2016-2020)

Teaching Graduate: Lectures in the following courses for PhD students, Cellular Biology (2000-2004), Molecular Endocrinology (2000-2003), Cellular Physiology (2000-2007), Advance Molecular Biology (2004-to-now), Introduction to Neuroscience (2004-to now), Advance Neuroscience (2001-to now) all of the Biomedical Science Program of the Faculty of Medicine. Organizer and teacher at the course Invertebrate Neurobiology (2006-)

International Workshops / Courses
Lectures in IBRO International School of Neuroscience, 2004 and 2006; Neurobiology of Drosophila (Organizer), 2003. Invited to the International Practical Course Neural Development, Montevideo, Uruguay
International Course Small Brains Big Ideas: Biomedical Insight from Invertebrate Research (Co-Organizer); www.smallbrains.org, 2010, 2012, 2014, 2016, 2019, 2022, 2024.

2023 Vice-president of the Biomedical Neuroscience (BNI) Institute Corporation
2021-2023 President Chilean Society of Biology
2022 President of the Biomedical Neuroscience Institute Corporation
2018-2021Deputy director of the Biomedical Neuroscience Institute
2018 to date Director of the Education (www.mentestranformadoras.cl) and dissemination (www.loligo.cl) Program at BNI
2017 Invited reviewer for the Canadian Grant competition
2015 Invited Member in the adjudication panel Canadian-Israel Program Grants
2009-2013 Member of the national committee for the selection of candidates to the Pew Latin American Fellowship. 2012-2013, President of the national committee.
2009-2021 President of the committee of the Master in Neuroscience Program, Faculty of Medicine, U. de Chile

Pew Latinamerican Fellowship

PEW LATIN AMERICAN FELLOWS PROGRAM IN BIOMEDICAL SCIENCES

Estados Unidos, 1996

Fellowship to do a postdoctoral training. I did 2 years at the laboratory of Dr. Charles ZUker at UCSD, La Jolla
Conicyt Fellowship

CONSEJO NACIONAL PARA INVESTIGACIONES CIENTIFICAS Y TECNOLOGICAS

Chile, 1989

Fellowship to carry out a PhD Program, at the Universidad de Chile


1. González-Gutiérrez A#, Gaete J, Esparza A, Toledo J, Köhler-Solis A, Sierralta J#. Visualizing Monocarboxylates and Other Relevant Metabolites in the Ex Vivo Drosophila Larval Brain Using Genetically Encoded Sensors Goinzález-Gutiérrez, A.; Gaete, Jorge; ESPARZA, ANDRÉS L; Toledo, Jorge; Kohler-Solis, Andres Article WOS JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2023)
A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer's disease models Xu, Dongwei; Vincent, Alec; Gonzalez-Gutierrez, Andres; Aleyakpo, Benjamin; Anoar, Sharifah; Giblin, A.; Atilano, Magda L.; Adams, Mirjam; Shen, Dunxin; Thoeng, Annora; Tsintzas, Elli; Maeland, Marie; Isaacs, Adrian M.; SIERRALTA-JARA, JIMENA ALEJANDRA; Niccoli, Teresa Article ISI SCOPUS PLOS GENETICS (2023)
Drosophila Atlastin regulates synaptic vesicle mobilization independent of bone morphogenetic protein signaling Bertin, Francisca; Jara-Wilde, Jorge; Auer, Benedikt; Koehler-Solis, Andres; Gonzalez-Silva, Carolina; Thomas, Ulrich; Sierralta, Jimena Article ISI BIOLOGICAL RESEARCH (2023)
Identification of <i>atlastin</i> genetic modifiers in a model of hereditary spastic paraplegia in <i>Drosophila</i> Candia, Noemi; Ibacache, Andres; Medina-Yanez, Ignacio; Olivares, Gonzalo H.; Ramirez, Mauricio; Vega-Macaya, Franco; Couve, Andres; Sierralta, Jimena; Olguin, Patricio Article ISI HUMAN GENETICS (2023)
Dlg Is Required for Short-Term Memory and Interacts with NMDAR in the Drosophila Brain Bertin, Francisca; Moya-Alvarado, Guillermo; Quiroz-Manriquez, Eduardo; Ibacache, Andres; Kohler-Solis, Andres; Oliva, Carlos; Sierralta, Jimena Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
The Fly Blood-Brain Barrier Fights Against Nutritional Stress Contreras, Esteban G.; Sierralta, Jimena Article ISI NEUROSCIENCE INSIGHTS (2022)
Whole-brain neuronal MCT2 lactate transporter expression links metabolism to human brain structure and function Medel, Vicente; Crossley, Nicolas; Gajardo, Ivana; Muller, Eli; Barros, L. Felipe; Shine, James M.; Sierralta, Jimena Article ISI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
Invertebrate Neuroscience: Contributions From Model and Non-model Species Fernandez, M. P.; Rittschof, C.C.; Sierralta, J Article wos FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2021)
Slit/Robo Signaling Regulates Multiple Stages of the Development of the Drosophila Motion Detection System Guzman-Palma, Pablo; Contreras, Esteban G.; Mora, Natalia; Smith, Macarena; Constanza Gonzalez-Ramirez, M.; Campusano, Jorge M.; Sierralta, Jimena; Hassan, Bassem A.; Oliva, Carlos Article ISI FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
The Serine Protease Homolog, Scarface, Is Sensitive to Nutrient Availability and Modulates the Development of the Drosophila Blood Brain Barrier Contreras, Esteban G.; Glavic, Alvaro; Brand, Andrea H.; Sierralta, Jimena A. Article ISI JOURNAL OF NEUROSCIENCE (2021)
Neuronal lactate levels depend on glia-derived lactate during high brain activity in Drosophila Gonzalez-Gutierrez, A; Ibacache, A; Esparza, A; Barros, LF; Sierralta, J Article ISI GLIA (2020)
Slit neuronal secretion coordinates optic lobe morphogenesis in Drosophila Caipo, Lorena; Gonzalez-Ramirez, M. Constanza; Guzman-Palma, Pablo; Contreras, Esteban G.; Palominos, Tomas; Fuenzalida-Uribe, Nicolas; Hassan, Bassem A.; Campusano, Jorge M.; Sierralta, Jimena; Oliva, Carlos Article ISI SCOPUS DEVELOPMENTAL BIOLOGY (2020)
Novel Strategies for the Generation of Neuronal Diversity: Lessons From the Fly Visual System Contreras, Esteban G.; Sierralta, Jimena; Oliva, Carlos Article ISI SCOPUS FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Chaski, a novel Drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional stress Delgado, MG; Oliva, C; Lopez, E; Ibacache, A; GALAZ, A; Delgado, R; Barros, LF; Sierralta, J Article ISI SCOPUS SCIENTIFIC REPORTS (2018)
Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1 alpha Sepulveda, D; Rojas-Rivera, D; Rodriguez, DA; Groenendyk, J; Kohler, A; Lebeaupin, C; Ito, S; Urra, H; Carreras-Sureda, A; Hazari, Y; Vasseur-Cognet, M; Ali, MMU; Chevet, E; Campos, G; Godoy, P; Vaisar, T; Bailly-Maitre, B; Nagata, K; Michalak, M; Sierralta, J; Hetz, C Article MOLECULAR CELL (2018)
p53 is required for brain growth but is dispensable for resistance to nutrient restriction during Drosophila larval development Glavic, Alvaro.; Sierralta, Jimena.; Contreras, Esteban G. Article ISI SCOPUS PLOS ONE (2018)
The transcription factor SoxD controls neuronal guidance in the Drosophila visual system Contreras, EG; Palominos, T; Glavic, A; Brand, AH; Sierralta, J; Oliva, C Article ISI SCOPUS SCIENTIFIC REPORTS (2018)
BAX inhibitor-1 regulates autophagy by controlling the IRE1 alpha branch of the unfolded protein response (vol 30, pg 4465, 2011) Castillo,Karen; Rojas-Rivera, Diego; Lisbona, Fernanda; Caballero, Benjamin; Nassif, Melissa;; Court, Felipe A.; Schuck, Sebastian; Ibar, Consuelo; Walter, Peter; Sierralta, Jimena.; Glavic, Alvaro.; Hetz, Claudio Article ISI EMBO JOURNAL (2017)
Drosophila Atlastin in motor neurons is required for locomotion and presynaptic function De Gregorio, C; Delgado, R; Ibacache, A; Sierralta, J; Couve, A Article JOURNAL OF CELL SCIENCE (2017)
Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca2+ Channels Astorga, César; Jorquera, Ramón A.; Ramírez, Mauricio; Kohler, Andrés; López, Estefanía; Delgado, Ricardo; Córdova, Alex; Olguín, Patricio; Sierralta, Jimena. Article ISI SCOPUS SCIENTIFIC REPORTS (2016)
Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex Oliva, Carlos; Soldano, Alessia; Mora, Natalia; DeGeest, Natalie; Claeys, Annelies; Erfurth, Maria-Luise; Sierralta, Jimena.; Ramaekers, Ariane; Dascenco, Dan; Ejsmont, RadoslawK.; Schmucker, Dietmar; Sanchez-Soriano, Natalia; Hassan, BassemA. Article ISI SCOPUS DEVELOPMENTAL CELL (2016)
Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and multiple genes involved in axon guidance in Drosophila Oliva, C; Molina-Fernandez, C; Maureira, M; Candia N; López E.; Hassan, B; Aerts, S; Canovas, J.; Olguin, P.; Sierralta, J Article ISI SCOPUS Developmental Neurobiology (2015)
The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a Canovas, J.; Berndt, FA; Sepulveda, H; Aguilar R.; Veloso FA; Montecino, M.; Oliva, C; Maass JC; Sierralta, J; Kukuljan M. Article ISI SCOPUS Journal of Neuroscience (2015)
Role of the maguk protein family in synapse formation and function Oliva, C; Escobedo, P.; Astorga, C.; Molina C.; Sierralta, J Article ISI SCOPUS Developmental Neurobiology (2012)
TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis Rojas-Rivera, D; Armisen, R; Colombo, A; Martinez, G; Eguiguren, A. L.; Diaz A.; Kiviluoto S; Rodriguez D.; Patron, M; Rizzuto, R; Bultynck G.; Concha, M. L.; Sierralta, J; Stutzin A.; hetz C. Article ISI SCOPUS CELL DEATH AND DIFFERENTIATION (2012)
BAX inhibitor-1 regulates autophagy by controlling the IRE1 alpha branch of the unfolded protein response Castillo, K; Rojas-Rivera, D; Lisbona, F; Caballero, B; Nassif, M; Court, FA; Schuck, S; Ibar C.; Walter P.; Sierralta, J; Glavic A.; hetz C. Article ISI SCOPUS EMBO JOURNAL (2011)
A Perisynaptic Menage a Trois between Dlg, DLin-7, and Metro Controls Proper Organization of Drosophila Synaptic Junctions Bachmann, A; Kobler, O.; Kittel, RJ; Wichmann C.; Sierralta, J; Sigrist, SJ; Gundelfinger ED; Knust, E; Thomas, U Article ISI SCOPUS Journal of Neuroscience (2010)
Regulation of axonal development by the nuclear protein hindsight (pebbled) in the Drosophila visual system Oliva, C; Sierralta, J Article ISI SCOPUS Developmental Biology (2010)
Endothelial Epithelial Sodium Channel Inhibition Activates Endothelial Nitric Oxide Synthase via Phosphoinositide 3-Kinase/Akt in Small-Diameter Mesenteric Arteries Perez, FR; Venegas, F; Gonzalez, M.; Andres S; Vallejos C.; RIQUELME, G; Sierralta, J; Michea, L. Article ISI SCOPUS HYPERTENSION (2009)
Expression of voltage-activated calcium channels in the early zebrafish embryo Sanhueza, D; Montoya A.; Sierralta, J; Kukuljan M. Article ISI SCOPUS ZYGOTE (2009)
DLGS97/SAP97 is developmentally upregulated and is required for complex adult behaviors and synapse morphology and function Mendoza-Topaz, C; Urra, F.; Barria, R; Albornoz, V; Ugalde, D; Thomas, U; Gundelfinger ED; Delgado, R; Kukuljan M.; Sanxaridis, PD; Tsunoda, S; Ceriani, MF; Budnik, V; Sierralta, J Article ISI SCOPUS JOURNAL OF NEUROSCIENCE (2008)
Temporal and spatial expression of Drosophila DLGS97 during neural development Albornoz, V; Mendoza-Topaz, C; Oliva, C; Tello, J; Olguin, P.; Sierralta, J Article ISI SCOPUS GENE EXPRESSION PATTERNS (2008)
Cell type-specific recruitment of Drosophila Lin-7 to distinct MAGUK-based protein complexes defines novel roles for Sdt and Dlg-S97 Bachmann, A; Timmer, M; Sierralta, J; Pietrini, G; Gundelfinger ED; Knust, E; Thomas, U Article ISI SCOPUS JOURNAL OF CELL SCIENCE (2004)
PDZ-containing proteins: alternative splicing as a source of functional diversity Sierralta, J; Mendoza C. Article ISI BRAIN RESEARCH REVIEWS (2004)
Novel isoforms of Dlg are fundamental for neuronal development in Drosophila Mendoza C.; Olguin, P.; Lafferte, G; Thomas, U; Ebitsch, S; Gundelfinger ED; Kukuljan M.; Sierralta, J Article ISI SCOPUS JOURNAL OF NEUROSCIENCE (2003)
Presence of Ca(2+)-dependent K(+) channels in chemosensory cilia support a role in odor transduction Delgado, R; Saavedra, MV; Schmachtenberg, O.; Sierralta, J; Bacigalupo, J Article ISI SCOPUS JOURNAL OF NEUROPHYSIOLOGY (2003)
PRESENCE OF CA2+-DEPENDENT K+ CHANNELS IN CHEMOSENSORY CILIA SUPPORT A ROLE IN ODOR TRANSDUCTION Delgado, Ricardo; Saavedra M.; Schmachtenberg, Oliver; Sierralta, Jimena.; Bacigalupo, Juan Article JOURNAL OF NEUROPHYSIOLOGY (2003)
A functional assay for paralytic shellfish toxins that uses recombinant sodium channels Velez, P.; Sierralta, J; Alcayaga, C; fonseca, M; Loyola, H; Johns, DC; Tomaselli, GF; Marban, E; Suarez-Isla, BA Article ISI SCOPUS TOXICON (2001)
Functionally heterogenous ryanodine receptors in avian cerebellum Sierralta, J; Suarez-Isla B.A.; Fill, M Article JOURNAL OF BIOLOGICAL CHEMISTRY (1996)
Modal gating in neuronal and skeletal muscle ryanodine-sensitive Ca2+ release channels Suarez-Isla B.A.; Armisen, R; Sierralta, J; Velez, P.; Naranjo, D Article AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (1996)


Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and multiple genes involved in actin regulation and axon targeting in Drosophila Olguin, P.; Oliva, C; Maureira, M; Canovas, J.; Molina-Fernandez, C; López E.; Sierralta, J Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2014)
Jitterbug(jbug)/Filamin and Protein Tyrosine Phosphatase 69D (PTP69D) are required for tendon cell orientation and axon targeting in Drosophila. Olguin, P.; Molina C.; Sierralta, J; López E.; Oliva, C Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2012)


How doth the little busy bee: unexpected metabolism Barros, LF; Sierralta, J; Weber, B. EditorialMaterial ISI SCOPUS Trends in Neurosciences (2015)


Presynaptic calcium signal in glutamatergic synapses=> role of scaffold proteins in its modulation. FONDECYT (1171800) Proyecto 2017-2019 Inv. Responsable
Role of the putative monocarboxylate transporter CG3409 (chaski) on the adaptive response of Drosophila melanogaster to nutritional restriction during development FONDECYT (3170905) Proyecto 2017-2019 Inv. Patrocinante
Biomedical Neuroscience Institute (BNI) ICM-Ministerios de Economía (P09015F) Proyecto 2016-2021 Inv. Principal
Drosophila Ring in Developmental Adaptations to Nutritional Stress (DRiDANS) Conicyt-DRI (1401) Proyecto 2016-2018 Inv. Principal
Drosophila Ring in developmental adaptations to nutritional stress PIA (1401) Proyecto 2015-2018 Coinvestigador(a)
The cell biology of hereditary spastic paraplegias using Drosophila as a model organism CONICYT-DRI (CONICYT-USA 201300020) Proyecto 2014-2017 Coinvestigador(a)
FINE TUNNING OF THE UPR=> FUNCTIONAL ANALYSIS OF THE IRE1ALPHA INTERACTOME FONDECYT (3130365) Proyecto 2012-2015 Inv. Patrocinante
Instituto de Neurociencia Biomédica ICM-Ministerio de Economía (ICM P09-015-F) Proyecto 2012-2016 Inv. Principal
MECHANISMS OF CELL ADAPTATION TO INTER-TISSUE MECHANICAL STRESS DURING MORPHOGENESIS, THE ROLE OF DROSOPHILA FILAMIN(JITTERBUG) AND CHASCON. FONDECYT (1120253) Proyecto 2012-2016 Coinvestigador(a)
ROLE OF THE DROSOPHILA MAGUK PROTEIN DLGS97 IN LEARNING AND MEMORY FONDECYT (1120684) Proyecto 2012-2016 Inv. Responsable
Núcleo de Morfogénesis Neuronal. ICM-Ministerio de Economía (ICM P07-048-F) Proyecto 2009-2011 Inv. Principal
ROLE OF DROSOPHILA DLG IN SYNAPTIC PLASTICITY FONDECYT (1090272) Proyecto 2009-2012 Inv. Responsable
ROLE OF REST/NRSF, COREST AND MIR124A DURING NEUROGENESIS AND NEURONAL DIFFERENTIATION IN VIVO FONDECYT (1090281) Proyecto 2009-2012 Coinvestigador(a)
Centro para el análisis de la función génica en el desarrollo neural. CONICYT (ACT-47) Proyecto 2006-2008 Inv. Principal
ESTUDIO DE LA FUNCION DEL GEN DE DROSOPHILA D-AXUD1 COMO SUPRESOR TUMORAL Y EN EL MANTENIMIENTO DE LA INTEGRIDAD EPITELIAL, Y DE SUS INTERACCIONES CON LA RUTAS DE SENALIZACION TGF-BETA Y WNT. FONDECYT (3050042) Proyecto 2004-2006 Inv. Patrocinante
PAPEL DE CANALES DE CALCIO EN EL ESTABLECIMIENTO DEL PATRON DORSOVENTRAL EN EL EMBRION DE XENOPUS LAEVIS. FONDECYT (1040829) Proyecto 2004-2007 Coinvestigador(a)
PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA FONDECYT (7040129) Proyecto 2004-2005 Inv. Responsable
PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA FONDECYT (7030079) Proyecto 2003-2004 Inv. Responsable
PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA FONDECYT (1030795) Proyecto 2003-2006 Inv. Responsable
PAPEL DE DlgB EN LA LOCALIZACION DE INAD Y EL COMPLEJO DE FOTOTRANSDUCCION DE DROSOPHILA MELANOGASTER FONDECYT (1000824) Proyecto 2000-2002 Inv. Responsable
ACTIVACION DE CANALES DE LIBERACION DE CA2+ SENSIBLES A RYANODINA FOTOLISIS DE COMPUESTOS ENJAULADOS. ACOPLAMIENTO CITOSOL-LUMEN Y MODOS DE ACTIVACION DE CONDICIONES DE ALTA RESOLUCION TEMPORAL FONDECYT (1950632) Proyecto 1995-1998 Coinvestigador(a)
CARACTERIZACION BIOQUIMICA Y ELECTROFISIOLOGICA DE LOS CANALES DE LIBERACION DE CALCIO PRESENTES EN EL RETICULO ENDOPLASMICO DE LAS NEURONAS DE HIPOCAMPO. FONDECYT (2930003) Proyecto 1993-1996 Inv. Responsable
SINTESIS Y DEGRADACION DE INOSITOL TRISFOSFATO EN MUSCULO ESQUELITICO FONDECYT (1911116) Proyecto 1991-1993 Coinvestigador(a)

Jimena Sierralta

Full Professor

Neuroscience

Faculty of Medicine, Universidad de Chile

Santiago, Chile

Carlos Oliva

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

Patricio Olguín

Assistant Professor

Facultad de Medicina, ICBM, Departamento de Neurociencia

Universidad de Chile

Santiago, Chile

Ricardo Delgado

Profesor Adjunto

Biología

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE BIOLOGIA

Santiago, Chile

Esteban Contreras

Postdoc

Institut für Neuro- und Verhaltensbiologie

Westfälische Wilhelms-Universität Münster

Münster, Alemania

Alvaro Glavic

Associate Professor

Departamento de Biología

Universidad de Chile

Santiago, Chile

Miguel Maureira

Estudiante de Doctorado

Facultad de Odontología

Universidad de Chile

Santiago, Chile

Karen Castillo

Académica Investigadora

,Centro de Investigación de Estudios Avanzados del Maule (CIEAM)

Universidad Catolica del Maule

Talca, Chile

Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

Cesar Astorga

Postdoctorado

Cs Biomedicas

Universidad Andrés Bello

Santiago, Chile

Felipe Court

Full Professor and Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

maria gonzalez

candidata a Phd

Ciencias Biológicas

Pontificia Universidad Católica de Chile

santiago, Chile

Juan Maass

Asistan Professor

universidad de chile

Santiago, Chile

ALEX GALAZ

COFOUNDER (Co-CEO)

INFOOD PROTEIN AND BIOTECHNOLOGY

VALDIVIA, Chile

Andro Montoya

Docente de Laboratorio de Biología Celular

Instituto de Ciencias Naturales

Universidad de Las Américas

Santiago, Chile

Diego Rojas

Assistant Professor

Center for Integrative Biology

Universidad Mayor

Santiago, Chile

Maria Lisbona

Postdoctorado

Biología

Universidad de Chile

Santiago, Chile

Rodrigo Aguilar

Assistant Professor

Institute for Biomedical Sciences

Universidad Andrés Bello

Santiago, Chile

Melissa Calegaro

Principal Investigator, head lab

Research Vice Presidency

Universidad Mayor

Santiago, Chile

Ramon Jorquera

Assistant Professor

Facultad de Medicina

Universidad Andrés Bello

Santiago, Chile

Martín Montecino

Director

Institute of Biomedical Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Dayan Sanhueza

Postdoctorado

Universidad Andrés Bello

Santiago, Chile

Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

Francisca Bertin

Investigador Postdoctoral

Psicología

Universidad de Chile

Santiago, Chile

Andrés González

Staff Scientist

Neurociencias

Instituto de Neurociencia Biomédica

Santiago, Chile

Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

Alicia Colombo

Profesora Asociada/Director Científico Biobanco de Tejidos y Fluidos de la Universidad de Chile

Departamento de Anatomía Patológica

Universidad de Chile

Santiago, Chile

Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

Oliver Schmachtenberg

Investigador titular

Instituto de Biología

Universidad de Valparaíso, CINV

Valparaíso, Chile

Vicente Medel

Lead Investigator

Latin American Brain Health Institute (BrainLat)

Universidad Adolfo Ibánez

Santiago, Chile

Jorge Campusano

Associate Professor

Cell & Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Gonzalo Olivares

ASSISTANT PROFESSOR

NEUROCIENCIA

Universidad de Chile

SANTIAGO, Chile

Jimena Alejandra Sierralta Jara

Líneas de Investigación

Educación

biochemistry, Pontificia Universidad Católica de Chile. Chile, 1988

Sciences, BIology, UNIVERSIDAD DE CHILE. Chile, 1996

Biochemist, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1988

Experiencia Académica

Associate Professor Full Time

Assistant Professor Full Time

Full Professor Full Time

Experiencia Profesional

Full Professor Full Time

Formación de Capital Humano

Premios y Distinciones

Pew Latinamerican Fellowship

Conicyt Fellowship

Article (40)

Abstract (2)

EditorialMaterial (1)

Proyecto (23)

Presynaptic calcium signal in glutamatergic synapses=> role of scaffold proteins in its modulation.

Role of the putative monocarboxylate transporter CG3409 (chaski) on the adaptive response of Drosophila melanogaster to nutritional restriction during development

Biomedical Neuroscience Institute (BNI)

Drosophila Ring in Developmental Adaptations to Nutritional Stress (DRiDANS)

Drosophila Ring in developmental adaptations to nutritional stress

The cell biology of hereditary spastic paraplegias using Drosophila as a model organism

FINE TUNNING OF THE UPR=> FUNCTIONAL ANALYSIS OF THE IRE1ALPHA INTERACTOME

Instituto de Neurociencia Biomédica

MECHANISMS OF CELL ADAPTATION TO INTER-TISSUE MECHANICAL STRESS DURING MORPHOGENESIS, THE ROLE OF DROSOPHILA FILAMIN(JITTERBUG) AND CHASCON.

ROLE OF THE DROSOPHILA MAGUK PROTEIN DLGS97 IN LEARNING AND MEMORY

Núcleo de Morfogénesis Neuronal.

ROLE OF DROSOPHILA DLG IN SYNAPTIC PLASTICITY

ROLE OF REST/NRSF, COREST AND MIR124A DURING NEUROGENESIS AND NEURONAL DIFFERENTIATION IN VIVO

Centro para el análisis de la función génica en el desarrollo neural.

ESTUDIO DE LA FUNCION DEL GEN DE DROSOPHILA D-AXUD1 COMO SUPRESOR TUMORAL Y EN EL MANTENIMIENTO DE LA INTEGRIDAD EPITELIAL, Y DE SUS INTERACCIONES CON LA RUTAS DE SENALIZACION TGF-BETA Y WNT.

PAPEL DE CANALES DE CALCIO EN EL ESTABLECIMIENTO DEL PATRON DORSOVENTRAL EN EL EMBRION DE XENOPUS LAEVIS.

PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA

PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA

PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA

PAPEL DE DlgB EN LA LOCALIZACION DE INAD Y EL COMPLEJO DE FOTOTRANSDUCCION DE DROSOPHILA MELANOGASTER

ACTIVACION DE CANALES DE LIBERACION DE CA2+ SENSIBLES A RYANODINA FOTOLISIS DE COMPUESTOS ENJAULADOS. ACOPLAMIENTO CITOSOL-LUMEN Y MODOS DE ACTIVACION DE CONDICIONES DE ALTA RESOLUCION TEMPORAL

CARACTERIZACION BIOQUIMICA Y ELECTROFISIOLOGICA DE LOS CANALES DE LIBERACION DE CALCIO PRESENTES EN EL RETICULO ENDOPLASMICO DE LAS NEURONAS DE HIPOCAMPO.

SINTESIS Y DEGRADACION DE INOSITOL TRISFOSFATO EN MUSCULO ESQUELITICO