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RENAN FELIPE ORELLANA WALDEN

Investigador

Universidad Bernardo O'Higgins

Santiago, Chile

Efecto de las plaquetas en cáncer de Ovario. Endometriosis y procesos invasivos en modelos animales. Disrruptores endocrinos y reproducción humana

Fisiologia, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2014
Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2012
Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2010

Profesor Asociado Other

Universidad Bernardo Ohiggins

Ciencias de la Salud

Santiago, Chile

2020 - A la fecha
Profesor Asistente Other

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

Santiago, Chile

2015 - 2019
Director Programa de Magíster en Ciencias Químico Biológicas Full Time

UNIVERSIDAD BERNARDO O'HIGGINS

Facultad de Ciencias de la Salud

Chile

2019 - A la fecha

Coordinador Académico Other

Universidad Bernardo OHiggins

Santiago, Chile

2016 - A la fecha
Profesor Asociado Full Time

Universidad Bernardo OHiggins

Santiago, Chile

2020 - A la fecha
Post Doctor Full Time

Universite Catholique de Louvain

Bruselas, Bélgica

2014 - 2016

Director de Tesis de Pregrado para optar al Título de Obtetricia y Puericultura UBO “CUANTIFICACIÓN DE LOS RECEPTORES DE PROGESTERONA EN BIOPSIAS DE TEJIDO ENDOMETRIÓTICO DE PACIENTES DEL HOSPITAL CLÍNICO DE LA RED DE SALUD UC CHRISTUS”.

Investigador Patrocinante FONDECYT POSTDOCTORADO NACIONAL 3200591

CEO ZKELETLAB compañía dedicada a la creación de Software de manejo de investarios de laboratorios


Students in biomedical careers can learn about Organic Chemistry and Botany by studying medicinal plants El estudiantado de carreras biomédicas puede aprender Química Orgánica y Botánica investigando sobre plantas medicinales Cortés Cortés, Manuel Enrique; Becerra, Álvaro; Martinez, Ivan; Orellana, Renan Article SCOPUS (2024)
Estetrol Increases Progesterone Genetic Response without Triggering Common Estrogenic Effects in Endometriotic Cell Lines and Primary Cultures Patino-Garcia, Daniel; Palomino, Jaime; Pomes, Cristian; Celle, Claudia; Torres-Estay, Veronica; Orellana, Renan Article ISI BIOMEDICINES (2023)
Molecular Characterization of Embryos with Different Buoyancy Levels in the Yellowtail Kingfish (Seriola lalandi) Dettleff, Phillip; Rodriguez, Javiera; Patino-Garcia, Daniel; Orellana, Renan; Castro, Rodrigo; Escobar-Aguirre, Sebastian; Daniel Moreno, Ricardo; Palomino, Jaime Article ISI Animals (2022)
A decrease of docosahexaenoic acid in testes of mice fed a high-fat diet is associated with impaired sperm acrosome reaction and fertility Bunay, Julio; Gallardo, Luz-Maria; Luis Torres-Fuentes, Jorge; Veronica Aguirre-Arias, M.; Orellana, Renan; Sepulveda, Nestor; Moreno, Ricardo D. Article ISI ASIAN JOURNAL OF ANDROLOGY (2021)
Embryo Buoyancy and Cell Death Gene Expression During Embryogenesis of Yellow-Tail Kingfish Seriola lalandi Palomino, Jaime; Gomez, Camila; Otarola, Maria Teresa; Dettleff, Phillip; Patino-Garcia, Daniel; Orellana, Renan; Moreno, Ricardo D. Article ISI FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Daily exposure to phthalates and alkylphenols alters miR biogenesis and expression in mice ovaries Patino-Garcia, Daniel; Cruz-Fernandes, Leonor; Bunay, Julio; Orellana, Renan; Moreno, Ricardo D. Article ISI JOURNAL OF MOLECULAR ENDOCRINOLOGY (2020)
Antigen retrieval by citrate solution improves western blot signal PatiÃ±o-GarcÃa D.; Rocha-PÃ©rez N.; Moreno, R.D.; Orellana R. Article ISI SCOPUS MethodsX (2019)
Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression Erices, Rafaela; Cubillos, Sofía; Aravena, Raúl; Santoro, Felice; Marquez, Monica; Orellana, Renan; Ramírez, Carolina; González, Pamela; Fuenzalida, Patricia; Loreto Bravo, María; Oliva, Bárbara; Kato, Sumie; Ibañez, Carolina; Brañes, Jorge; Bravo, Erasmo; Alonso, Catalina; García, Karen; Arab, Clemente; Torres, Vicente A.; Godoy, Alejandro S.; Pereira, Jaime; Bustos, Galdo; Cesar Cardenas, Julio; Cuello, Mauricio A.; Owen, Gareth I. Article ISI SCOPUS ONCOTARGET (2017)
Gynecological and obstetrical outcomes after laparoscopic repair of a cesarean scar defect in a series of 38 women Donnez, Olivier; Donnez, Jacques; Orellana, Renan; Dolmans, Marie-Madeleine Article ISI FERTILITY AND STERILITY (2017)
Important role of collective cell migration and nerve fiber density in the development of deep nodular endometriosis Orellana, Renan; Garcia-Solares, Javier; Donnez, Jacques; van Kerk, Olivier; Dolmans, Marie-Madeleine; Donnez, Olivier Article ISI FERTILITY AND STERILITY (2017)
Development of a transplantable artificial ovary: influence of follicle stage on transplantation outcome Maria Costanza, Chiti; Marie Madeleine, Dolmans; Renan, Orellana; Michelle, Soares; Fernanda, Paulini; Carolina Madeira, Lucci; Jacques, Donnez; Christiani Andreade, Amorim Article FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2016)
Endometriosis and Infertility Donnez J, Donnez O, Orellana R, Binda MM, Dolmans MM. Article PANMINERVA MEDICA (2016)
Influence of follicle stage on artificial ovary outcome using fibrin as a matrix Chiti, M. C.; Dolmans, M. M.; Orellana, R.; Soares, M.; Paulini, F.; Donnez, J.; Amorim, C. A. Article ISI HUMAN REPRODUCTION (2016)
Invasion process of induced deep nodular endometriosis in an experimental baboon model: similarities with collective cell migration? Donnez, Olivier; Orellana, Renan; Van Kerk, Olivier; Dehoux, Jean-Paul; Donnez, Jacques; Dolmans, Marie-Madeleine Article Fertility and Sterility (2015)
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells Orellana, R; Kato, S; Erices, R.; Bravo, ML; Gonzalez P.; Oliva, B.; Cubillos S; Valdivia, A; Ibáñez C; Brañes J.; Barriga MI.; Bravo, E.; Alonso,C.; Bustamente, E; Castellón E.; Hidalgo, P.; Trigo, C; Panes O.; Pereira J.; Mezzano D.; Cuello, MA; Owen, GI Article ISI SCOPUS BMC Cancer (2015)
Simvastatin modifies the expression of stemness and epithelial-mesenchymal transition (EMT) markers in ovarian cancer-initiating cells resulting in decreased cell migration Kato, S.; Abarzua, L.; Hormazabal, K.; Delpiano, A.; Bravo, M. L.; Orellana, R.; Branes, J.; Castellon, E.; Cuello-Fredes, M.; Owen, G. I. Article ISI EUROPEAN JOURNAL OF CANCER (2014)
Concanavalin-A Induces Granulosa Cell Death and Inhibits FSH-Mediated Follicular Growth and Ovarian Maturation in Female Rats Velasquez EV; Rios M.; Ortiz ME; Lizama C.; Núñez E.; Abramovich, D; Orge, F; Oliva, B.; Orellana, R; Villalón M.; Moreno, RD; Tesone, M; Rokka, A; Corthals, G; Croxatto HB; Parborell, F; Owen, GI Article ISI SCOPUS ENDOCRINOLOGY (2013)
Modulation of spermatozoon acrosome reaction Vigil P, Orellana RF, Cortés ME Article BIOLOGICAL RESEARCH (2011)


Platelet interaction induces Tissue Factor and a pro-metastatic phenotype in ovarian cancer cells Orellana, RF; Oliva, B.; Kato, S; Bravo, L; Gonzalez P.; Panes O.; Mezzano D.; Cuello, M.; Owen, G Abstract ISI CANCER RESEARCH (2014)


An essential reference to be incorporated in the article: Inhibitory effects of estetrol on the invasion and migration of immortalized human endometrial stromal cells Orellana-Walden, Renan; Patino-Garcia, Daniel Letter ISI ENDOCRINE JOURNAL (2024)
Plantas medicinales chilenas: desde el saber ancestral a la comercialización poco regulada Valentina B. González-Garrido; Diego A. Jiménez-Baltierra; Renán Orellana; Manuel E. Cortés Letter ISI SCIELO REVISTA MEDICA DE CHILE (2022)
Cannabis and the teenager's brain Cortés, Manuel E.; Bernal, Yanara; Orellana, Renán Letter ISI SCIELO SCOPUS REVISTA MEDICA DE CHILE (2019)


Effects of a defined mixture of phthalates on ovarian Endometriosis progression Patiño-Garcia, Daniel; INVESTIGADOR PATROCINANTE Proyecto (2020)
Determination of estetrol effects in proliferation and progesterone resistance in endometriosis FONDECYT (11170603) Proyecto 2017-2020 Inv. Principal
MODULATION OF THE PROCESS OF ANGIOGENESIS BY COAGULATION FACTOR X FONDECYT (1140970) Proyecto 2014-2018 Tesista
Contribución de las plaquetas en la diseminación del cáncer de ovario PFCHA (21100817) Proyecto 2010-2014 Tesista
STUDY OF A NOVEL HUMAN FOLLICLE STIMULATING HORMONE (FSH) VARIANT=> ELUCIDATION OF THE PHYSIOLOGICAL ROLE AND PATHOLOGICAL IMPLICATIONS FONDECYT (1100870) Proyecto 2010-2014 Tesista


New Solutions for Old Problems: How Reproductive Tissue Engineering Has Been Revolutionizing Reproductive Medicine Leonel, Ellen C. R.; Dadashzadeh, Arezoo; Moghassemi, Saeid; Vlieghe, Hanne; Wyns, Christine; Orellana, Renan; Amorim, Christiani A. Review ISI ANNALS OF BIOMEDICAL ENGINEERING (2023)
Endocrine Modulation of the Adolescent Brain: A Review Vigil, P; Orellana, RR; Cortes ME; Molina, CT; Switzer, BE; Klaus H. Review ISI SCOPUS Journal of Pediatric and Adolescent Gynecology (2011)