Man

Mauricio Arturo Pinto Paganini

Investigador

STORM SPA

Santiago, Chile

Líneas de Investigación


Gastric cancer, ovarian cancer, breast cancer; targeted therapies in cancer, 3D models; epithelial-stroma interactions

Educación

  •  Ciclo basico en ciencias biologicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1997
  •  Doctorado en Ciencias Biologicas Mencion Ciencias Fisiologicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2005
  •  Biologo especializacion bioprocesos, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1998

Experiencia Académica

  •   Profesor asistente Full Time

    UNIVERSIDAD ANDRES BELLO

    2014 - 2016

Experiencia Profesional

  •   Investigador postdoctoral/ postdoctoral fellow

    Universidad de Colorado

    Estados Unidos

    2005 - 2010

  •   Instructor of Medicine (faculty)

    Universidad de Colorado

    Estados Unidos

    2010 - 2013

  •   Investigador Full Time

    STORM SPA

    Santiago, Chile

    2017 - A la fecha


 

Article (30)

Complete Response to Immunotherapy Plus Chemotherapy After an Unusual Clinical Response to Afatinib and Stereotactic Radiosurgery in a Patient With Metastatic EGFR-Mutant Non–Small-Cell Lung Cancer
Cost-minimization analysis of subcutaneous versus intravenous trastuzumab administration in Chilean patients with HER2-positive early breast cancer
Eribulin-induced radiation recall dermatitis: a case report and brief review of the literature
First-line endocrine therapy for advanced breast cancer. A real-world study at a Latin American university health institution
Mammography correlates to better survival rates in breast cancer patients: a 20-year experience in a University health institution
Biliary tract cancer prognostic and predictive genomics
Chilean Registry for Neuroendocrine Tumors: A Latin American Perspective
Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation
Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry?
High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study
Patient inflammatory status and CD4+/CD8+ intraepithelial tumor lymphocyte infiltration are predictors of outcomes in high-grade serous ovarian cancer
The antinociceptive effect of resveratrol in bone cancer pain is inhibited by the Silent Information Regulator 1 inhibitor selisistat
Structural and functional identification of vasculogenic mimicry in vitro
Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells
Behavioral characterization of a model of differential susceptibility to obesity induced by standard and personalized cafeteria diet feeding
Independent Anti-Angiogenic Capacities of Coagulation Factors X and Xa
Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells
Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling
Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease
Progesterone regulation of tissue factor depends on MEK1/2 activation and requires the proline-rich site on progesterone receptor
Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch
Vascular Endothelial Growth Factor Secreted by Activated Stroma Enhances Angiogenesis and Hormone-Independent Growth of Estrogen Receptor-Positive Breast Cancer
Regulation of GLUT3 and glucose uptake by the cAMP signalling pathway in the breast cancer cell line ZR-75
Estrogen insensitivity in a model of estrogen receptor-positive breast cancer lymph node metastasis
In vivo and in vitro estrogenic and progestagenic actions of Tibolone
Progesterone increases tissue factor gene expression, procoagulant activity, and invasion in the breast cancer cell line ZR-75-1
Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75
Tissue factor is regulated by epidermal growth factor in normal and malignant human endometrial epithelial cells
Differential regulation of glucose transporter expression by estrogen and progesterone in Ishikawa endometrial cancer cells
Estrogen and progesterone up-regulate glucose transporter expression in ZR-75-1 human breast cancer cells

Proyecto (5)

Systematically evaluation of the mechanistic synergism between MAPK kinase inhibitor with clinically approved cytotoxic agents
Modulation of the process of angiogenesis by Factor X
Desarrollo de in kit diagnostico, o servicio, para predecir la respuesta y toxicidad de los tratamientos de quimioterapia en cada paciente
Effect of statins in the maintenance, differentiation and drug sensitivity of cancer-initiating cells in ovarian cancer
DEVELOPMENT OF AN ER-POSITIVE BREAST CANCER METASTASIS MODEL THROUGH STROMAL-EPITHELIAL INTERACTIONS

Review (3)

Angiogenesis inhibitors in early development for gastric cancer
Targeted brain delivery nanoparticles for malignant gliomas
2-Methoxyestradiol and Disorders of Female Reproductive Tissues
33
Mauricio Pinto

Investigador

STORM SPA

Santiago, Chile

16
Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

9
Andres Carvajal

Investigador

INIA

Osorno, Chile

6
Cesar Sanchez

Profesor asistente

Hematologia-oncologia

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

santiago, Chile

6
Francisco Acevedo

Medico Oncologo

Hemato Oncologia

Pontificia Universidad Católica de Chile

Santiago, Chile

4
Bruno Nervi

Associated Professor

Hematology - Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

4
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

3
María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

3
Miguel Cordova

Estudiando de Doctorado

Departamento de Posgrado

Universidad de Chile

Santiago, Chile

3
Ignacio Retamal

Docente

Universidad de Los Andes

Santiago, Chile

3
Ana Meneses

Académico

Universidad Diego Portales

Santiago, Chile

2
ALEJANDRO CORVALAN

Associate Professor

Hematology and Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Marcelo Kogan

Academico

Quimica Farmacologica y Toxicologica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

2
Erica Koch

Oncólogo Médico

Red de Salud UC Christus

Santiago, Chile

2
María Villarroel

Médico Anátomo-Patólogo

Anatomía Patológica

Red de Salud UC Christus / Pontificia Universidad Católica de Chile

Santiago, Chile

2
Allisson Astuya

profesor asociado

Departamento de Oceanografia de la Universidad de Concepción

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

2
Juan Vera

Full professor

Pathophysiology

University of Concepcion

Concepción, Chile

1
Claudia Saez

Associate Professor

Hematology-Oncology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Ethel Velásquez

investigador

Departamento de Tecnologías Nucleares

Comisión Chilena de Energía Nuclear

Santiago, Chile

1
Edison Salas

Director de laboratorio de nanotecnología

Aintech

Santiago, Chile

1
Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

1
Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

1
María Maturana

Bioquimico

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Alvaro Lladser

Professor, Principal Investigator

FUNDACIÓN CIENCIA PARA LA VIDA

Santiago, Chile

1
Alexis Kalergis

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

1
Ignacio Espinoza

Profesor Asistente

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Fabian Tempio

Asistente de Investigación

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

1
Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

1
Marcelo Garrido

Director

CENTRO DEL CÁNCER, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Flavio Salazar

Profesor titular

Instituto de ciencias biomédicas

Universidad de Chile

SANTIAGO, Chile

1
Fabiola Sánchez

Associate Profesor

Immunology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Claudio Perez

Profesor Asistente

Departamento de Ciencias Fisiológicas

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Cristian Vilos

Profesor Jornada Completa

Medicina

Universidad de Talca

Talca, Chile

1
Luis Constandil

Profesor Titular

Biología

Universidad de Santiago de Chile

Santiago, Chile

1
Maria Gago

Profesor Asistente

Facultad de Física

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

1
Rafaela Erices

Postdoctorante

Ginecología y Obstetricia

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Paula Sotomayor

Investigador

Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Verónica Palma

Associate Professor

Biology

Universidad de Chile

Santiago, Chile

1
FERNANDO CROVARI

Jefe Departamento

Cirugía Digestiva

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Lorena Lobos

Principal Investigator-Associate Proffesor

Facultad of Medicine - Clinic Alemana

Universidad Del Desarrollo

santiago, Chile

1
jose valbuena

Associate Professor

Anatomic Pathology

PONTIFICIA UNIVERSIDAD CATOLICA. FACULTAD DE MEDICINA/ESCUELA DE MEDICINA/ DEPARTAMENTO DE ANATOMÍA PATOLÓGICA

santiago, Chile

1
German Osorio

Especialista en Microscopia

Biologia Celular

Universidad de Concepción

Concepción, Chile