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Verónica Alejandra Palma Alvarado

Associate Professor

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Sonic Hedgehog (SHH) regulation of the NETRIN/NEOGENIN1 axis in cancer. Mesenchymal stem cells (MSCs) as therapeutic agents for both tissue engineering and cancer therapy applications.

Educación

  •  Biomedical Sciences, UNIVERSIDAD DE CHILE. Chile, 2000
  •  Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1989
  •  postdoctoral training in biomolecular medicine, Skirball Institute of Biomolecular Medicine. Estados Unidos, 2003

Experiencia Académica

  •   undergraduate Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Biology

    Santiago, Chile

    1989 - 1995

  •   PhD in Biomedical Sciences Other

    UNIVERSIDAD DE CHILE

    Medicine

    Santiago, Chile

    1995 - 2000

  •   Postdoc Other

    Skirball Institute for Biomedical Sciences

    New York, Estados Unidos

    2000 - 2003

  •   Assistant Professor Full Time

    UNIVERSIDAD DE CHILE

    Sciences

    Santiago, Chile

    2003 - 2011

  •   Associate Professor Full Time

    UNIVERSIDAD DE CHILE

    Sciences

    Santiago, Chile

    2011 - A la fecha

Experiencia Profesional

  •   Associate Professor Full Time

    University of Chile

    Santiago, Chile

    2011 - A la fecha

  •   Assistant Professor Full Time

    University of Chile

    Santiago, Chile

    2003 - 2011

Formación de Capital Humano


Post doc Mentorship:
-Dr. Carmen Gloria Feijóo, (2005-2007). Post-Doctoral Research Fellow. Presently Assistant Professor at the Universidad Andres Bello (UNAB), Facultad de Ciencias Biologicas, Departamento de ciencias biologicas

-Dr. Luis Milla, (2010- 2011). Former postdoctoral training with Fondecyt grant #3100045. Presently Postdoctoral Researcher in the Laboratory of Matthew Scott, Departments of Developmental Biology, Genetics, and Bioengineering, Stanford University School of Medicine

-Dr. Catalina Prieto (2011- present). Fondef grant # D09I104. Presently postdoctoral researcher with Fondecyt grant #3140368.

Graduate student Mentorship:
-Gisela Reinchisi (2004-2008) Ph.D. current position: Postdoctoral fellow at University of Connecticut Health Center (Dr. N. Zecevic)
-Luis Milla (2005-2009) Ph.D. current position: Postdoctoral fellow Dr. Matthew Scott (Stanford University School of Medicine)
-Constanza Martinez (2007-2011) Ph.D. current position: Assistant Professor at the Pontificia Universidad Católica.
-Joao Botelho (2008-2014): Ph.D.
-Gabriela Zavala (2009-2014): Ph.D.
-Luis Solano (2011-): Ph.D.
-Paulina Falcón (2012-): Ph.D.
-Andrea Arros (2013-): Ph.D
-Daniel Meza (2014-): Ph.D.

-Pablo Lois (2008-2012): Master student.
-Claudio Cortés (2009-2011): Master student.
-Carolina Ortiz (2011-2013): Master student.
-Matías Elliot (2012-): Master student.
-Bárbara Casas (2013-): Master student.

Undergraduate student Mentorship:
Gustavo Cerda (2003-2006). Thesis project. Current position: Postdoc at Cambridge University, Great Britain.
Francisco Araya (2004-2007) Thesis project. Engineer in Molecular Biotechnology. Current position: PhD studies at the Faculty of Science, U. of Chile.
Maritza Oñate (2009- 2010) Thesis project. Engineer in Molecular Biotechnology. Current position: PhD studies at the Faculty of Biology, Catholic U. of Chile.
Victor Hugo Cornejo (2008-2010). Thesis project. Current position: PhD studies at the Faculty of Medicine, U. of Chile.
Natalie Espinoza Giacomozzi (20111-2012). Thesis project. Biochemist. Current position: Master student VP lab.
Samuel Martínez (2011-2012). Thesis project. Engineer in Molecular Biotechnology. Current position PhD studies at the Faculty of Science, U. of Chile.
Gabriela Zavala (2008-2013). Thesis project. Engineer in Molecular Biotechnology. Current position PhD studies at the Faculty of Science, U. of Chile.
Natalia Solis (2012-2013). Thesis project. Engineer in Molecular Biotechnology.
Andrea Arros (2012-2013). Thesis project. Engineer in Molecular Biotechnology. Current position PhD studies at the Faculty of Science, U. of Chile.
Sandra Edwards. (2012-2013). Thesis project. Engineer in Molecular Biotechnology. Current position PhD studies at the Faculty of Science, U. of Chile.
Sergio González (2013-)Thesis project. Engineer in Molecular Biotechnology.
Diego Sandoval (2014-) Thesis project. Engineer in Molecular Biotechnology.


Premios y Distinciones

  •   Member of the II Generation of young scientists, Chilean Academy of Science

    Chilean Academy of Science

    Chile, 2007

    Nominated by the Chilean Academy of Science with the Young Investigator Award and honor.

  •   Best student award for undergraduate studies

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 1993

    Best Student Award (honor for academic excellence) both 1992 and 1993

  •   Fellowship for graduate studies

    UNIVERSIDAD DE CHILE

    Chile, 1995

    1995-2000 CONICYT (Chilean National Council for Science and Technology) Fellowship for graduate studies

  •   Guillermo Puelma Foundation Fellowship for graduate studies

    Fundacion Guillermo Puelma

    Chile, 1999

    Guillermo Puelma Foundation Fellowship for graduate studies

  •   Supportive Program for Young Scientists Starting Research

    Andes Fundation, Chile

    Chile, 2003

    C-13860. Molecular characterization and rol of the SHH pathway during the development of the Central Nervous System (CNS) in vertebrates. Supportive Program for Young Scientists Starting Research Funding Organism: Andes Fundation, Chile 2003-2005


 

Article (22)

Functional Analysis Reveals Angiogenic Potential of Human Mesenchymal Stem Cells from Wharton's Jelly in Dermal Regeneration
Independent Anti-Angiogenic Capacities of Coagulation Factors X and Xa
Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression
Sonic hedgehog controls stem cell behaviour in the postnatal and adult brain.
The emergent design of the neural tube: prepattern, SHH morphogen and GLI code.
Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source
Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation
Sonic hedgehog (Shh)/Gli modulates the spatial organization of neuroepithelial cell proliferation in the developing chick optic tectum
Sonic Hedgehog in cancer stem cells: a novel link with autophagy
Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development
SHh activity and localization is regulated by perlecan
Sonic hedgehog (Shh)-Gli signaling controls neural progenitor cell division in the developing tectum in zebrafish
Sonic Hedgehog Stimulates Proliferation of Human Periodontal Ligament Stem Cells
Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos
Electroporation of DNA, RNA, and morpholinos into zebrafish embryos
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex
Calcium mediates dorsoventral patterning of mesoderm in Xenopus
Hyperkalemic periodic paralysis M 1592V mutation modifies activation in human skeletal muscle Na + channel
Sperm interaction with human oviductal cells in vitro
Hedgehog-Gli signaling and the growth of the brain
Independent anti-angiogenic capacities of coagulation factors X and Xa.
The Shh-Gli pathway modulates the normal and abnormal growth of the dorsal brain.

Abstract (2)

Sonic hedgehog (SHH) regulates c-myc expression in the developing brain: Direct or indirect link?
Sonic Hedgehog (SHH) role in dorsal midbrain proliferation in vertebrates
24
Verónica Palma

Associate Professor

Biology

Universidad de Chile

Santiago, Chile

15
Verónica Palma

Profesor Titular

Biología

UNIVERSIDAD DE CHILE

Santiago, Chile

3
Pablo Lois

Asistente de Investigación

Biología

Universidad de Chile

Santiago, Chile

3
Luis Milla

Profesor Asistente

Escuela de Medicina

Universidad de Santiago

Santiago, Chile

2
Constanza Martinez

Profesor asociado

Carrera de Odontología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - FACULTAD DE MEDICINA CARRERA DE ODONTOLOGÍA

Santiago de Chile, Chile

2
Carmen Feijóo

Profesor asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
Miguel Allende

Director

Biología

FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

1
Veronica Cambiazo

Associate Professor

Unidad de Nutrición Básica

UNIVERSIDAD DE CHILE - INTA

Santiago, Chile

1
Fernando Faunes

Profesor Asistente

Universidad Andrés Bello

Viña del Mar, Chile

1
Christian Hodar

ASSISTANT PROFESSOR

BIOINFORMATICS & GENEXPRESSION LAB - INTA

UNIVERSIDAD DE CHILE

Santiago, Chile

1
JOAO FRANCISCO

Profesor Asistente

Departamento de Biología Celular y Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Juan Agustín Larraín

Profesor Titular

Biologia Celular y Molecular

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Gonzalo Olivares

ASSISTANT PROFESSOR

NEUROCIENCIA

Universidad de Chile

SANTIAGO, Chile

1
Mauricio Pinto

Investigador

STORM SPA

Santiago, Chile

1
Víctor Cornejo

Associate Research Scientist

Biological Sciences

Columbia University

New York, Estados Unidos