Ana-pereira-investigadora_foto.jpg_thumb90

Ana Inés Pereira Scalabrino

Assistant Professor

Institute of Nutrition and Food Technology (INTA)

Santiago, Chile

Líneas de Investigación


Early determinants of Breast Cancer; Risk factors of greater Breast Density; Prevention and evaluation of the Cervical Cancer Program; Child Growth; Obesity; Public health

Educación

  •  Epidemiology and Population Health, London School of Hygiene and Tropical Medicine. Reino Unido, 2011
  •  Public Health, UNIVERSIDAD DE CHILE. Chile, 2005
  •  Medical Doctor, UNIVERSIDAD DE CHILE. Chile, 2002

Experiencia Académica

  •   Assistant Professor Full Time

    UNIVERSIDAD DE CHILE

    Institute of Nutrition and Food Technology (INTA)

    Santiago, Chile

    2011 - A la fecha

  •   Research assistant Part Time

    UNIVERSIDAD DE CHILE

    Medicine

    Santiago, Chile

    2004 - 2010

Experiencia Profesional

  •   Assistant Professor Full Time

    Institute of Nutrition and Food Technology (INTA)

    Santiago, Chile

    2011 - 2022

  •   Associate professor Full Time

    Institute of Nutrition and Food Technology (INTA)

    Santiago, Chile

    2022 - A la fecha

Formación de Capital Humano


ADVISOR PROFESSOR

DOCTORAL STUDENTS

2015 Angela Marcela Jaramillo. “Chronobiological pattern of food consumption and its association with obesity and metabolic risk in Chilean pubescents of the ECO cohort”.
Research Unit Advisor, Doctorate in Nutrition and Food, University of Chile

MASTER STUDENTS

2022 Viviana Vera. "Pandemic effect on the physical activity of adolescents of the echo cohort" [In progress]. Master in Nutrition, INTA, University of Chile.
2022 Joyce Singer Fichman. "Association of Ultraprocessed Foods in the development of chronic inflammation during adolescence". [In progress]. Master in Nutrition,
INTA, University of Chile.
2021 Tamara Bustamante. "Is alcohol consumption at an early age a risk factor that affects the breast density of adolescents?". [In progress]. Master in Public Health.
Medicine, University of Chile.
2019-2021 Claudia Carrasco. "A high energy density of the diet is associated with the breast density of girls during puberty". [Finished]. Master in Nutrition, INTA, University of
Chile.
2019-2020 María Eliana Pérez. "Role of folic acid in the composition of the breast". [Finished]. Master in Nutrition, INTA, University of Chile, Chile.
2017-2018 Joanna Paola Rojas Calisto. "Association between indicators of total and central body adiposity during childhood and age of menarche in Chilean adolescents".
[Finished]. Master in Nutrition, INTA, University of Chile.
2017-2019 Constanza Lesser. “Phytoestrogen intake is associated with breast composition in girls during puberty.” [Finished]. Master in Nutrition, INTA, University of Chile.
2017-2018 María Fernanda Solares Gutierrez. "Association between obesity and the time of onset of puberty in Chilean boys".[Finished]. Master in Nutrition, INTA, University
of Chile.
2015-2017 Ana López. “Effect of weight gain during pregnancy on the mammary density of daughters at puberty”. [Finished]. Master in Nutrition, INTA, University of Chile.
2013-2013 Diana Carolina Mesa. “Relationship between childhood adiposity and higher pre-pubertal estrogen levels in Chilean girls participating in the Chilean growth and
obesity study.” [Finished]. Master in Nutrition, INTA, University of Chile.

ADVISOR FOR FELLOWSHIP STUDENTS

2018 Julio Soto. “Clinical and hormonal characteristics of puberty in girls with transient thelarche”. [finished]. Specialization Scholarship in Endocrinology. Faculty of Medicine,
University of Chile.
2016 Mónica Fernández. "Onset of pubertal development and its progression in Chilean girls: Is there an association with ethnic origin?" [finished]. Specialization Scholarship
in Endocrinology. Faculty of Medicine, University of Chile.

CO-ADVISOR PROFESSOR

2021 Juan Pablo Espejo. “Adiposity trajectories and metabolic markers in metabolically ill obese and metabolically healthy obese”. [In progress]. Master in Nutrition, INTA,
University of Chile.
2021 Kelda Yeung. “Association between insulinemic diets and breast density in adolescent girls: a secondary data analysis of the Chilean Growth and Obesity Cohort Study”.
[In progress]. Master in Nutrition for Global Health. London School of Hygiene and Tropical Medicine, England.
2020 Ingrid Baier. “Relationship between estrogen and its metabolites and insulin sensitivity during pubertal development in Chilean girls”. [Finished]. Specialization
Scholarship in Endocrinology. Faculty of Medicine, University of Chile.


Difusión y Transferencia


WRITTEN AND DIGITAL PRESS

- Social Media: LinkedIn, Twitter. Since 2021, CIAPEC - INTA is actively making publications on social media in relation to: nutrition, food, cancer, chronic diseases, among others.
- Web Page INTA: "Breast cancer in Chile: A look from prevention". October 29th, 2021. Santiago, Chile
- Report for JUNAEB, Growth and Obesity Chilean Cohort Study (ECO) 2020 "Mental Health and Expectations about the future of adolescents in the context of the COVID-19 Pandemic". Published in official webpage and presented to research group. May 26th, 2021. Santiago, Chile
- Report for JUNAEB, Growth and Obesity Chilean Cohort Study (ECO) 2019 "Habits (cigarette consumption, use of screens, eating behavior, and hours of sleep) and their
association with nutritional status between the years 2016 to 2018" Published in official webpage and presented to research group. May 26th, 2021. January 2020. Chile.
- Nutrition and Life. "Endocrine disruptors and their effects on health". October 9th, 2019. Santiago, Chile
- Report for JUNAEB, Growth and Obesity Chilean Cohort Study (ECO) 2018 "Consumption of psychoactive substances and depression in adolescents". Published in official webpage and presented to research group. May 2019. Santiago, Chile.
- Report for JUNAEB, Growth and Obesity Chilean Cohort Study (ECO) 2017 "Physical Activity and Nutritional Status". Dissemination on the institutional page and presentation to the team. Wednesday, August 1st, 2018. Santiago, Chile.
- Instagram: Development of informative content aimed at young people about cancer risk factors, for publication on Growth and Obesity Chilean Cohort Study’s social media pages, from 2017 to present. Available at [Instagram.com/eco.inta](http://instagram.com/eco.inta)
- Organization of the 10-year anniversary of the Growth and Obesity Chilean Cohort Study(ECO) and communication of its results to participating families. June 2017. Records available at https://inta.cl/eco-celebro-su-decimo-aniversario-JUNTO-a-sus-participantes-y-profesionales-involucrados/
- Cooperativa Radio channel - “Justa Medida”. “Nutrition and Cancer”, Dra. Ana Pereira interviewed by Verónica Franco and Sylvia Cruchet. April 16th, 2014.

MEMBER OF EXPERTS' COMMITTEE

- Participant as expert in the development and review of the GES Breast Cancer Clinical Guide, Ministry of Health, 2014. The objective of this activity was to review the literature in relation to promotion, prevention, diagnosis, treatment and rehabilitation of breast cancer. This information was essential to the development and review of the clinical guideline for Chile.
- Participant as expert in the development and revision of the GES Clinical Guide for Cervical Cancer, Ministry of Health, 2009. The objective of this activity was to review the literature in relation to promotion, prevention, diagnosis, treatment and rehabilitation of cervical-uterine cancer. The evidence collected was essential to the development and review of the clinical guideline for Chile.
- Reviewer of the CONICYT-ANID Advanced Human Capital Training Program. From 2018 to date
- Member of the Fondecyt Program Expert Panel- ANID group G2- G3 for project evaluation, from May 2021- to date
- Member of the FONIS study group for projects evaluation in 2011


Premios y Distinciones

  •   Benjamin Viel

    UNIVERSIDAD DE CHILE

    Chile, 2003

    Award to the best student in Epidemiology

  •   Best Contribution

    SOCIEDAD CHILENA DE OBSTETRICIA Y GINECOLOGIA

    Chile, 2007

    1st Chilean Gyneco-Oncology Conference 11-14 November 2007. Title “Methodological issues to study incidence and mortality of Cervical Cancer determinants in the North Area of Santiago”.

  •   II Santander Award for University Scientific Research. Senior Category.

    Santander Bank. Santander Universities Global Division.

    Chile, 2013

    Award to recognize and support scientific research, an initiative that seeks to promote science development for the benefit of health.

  •   Award for the Best Endocrinology Work

    CHILEAN SOCIETY OF ENDOCRINOLOGY AND DIABETES

    Chile, 2021

    “Differential Methylation of Genes of the Biosynthetic Pathway of 11-oxyandrogens in girls with high levels of DHEAS”, Rodriguez F, Ponce D, Santos JL, Pereira A, Lardone C, Mirana J, Iñiguez G, Mericq V. XXXII SOCHED Congress. November 9-14, 2021.


 

Article (66)

Association between plasma leptin/adiponectin ratio and insulin resistance indexes in prepubertal children
Breast composition during and after puberty: the Chilean Growth and Obesity Cohort Study
Post menarcheal growth patterns in a contemporary cohort of Latino girls
Time-specific impact of trace metals on breast density of adolescent girls in Santiago, Chile
Association Between Markers of Adiposity During Childhood and Puberty Onset in Latino Girls
Dietary Iron Intake in Relation to Age at Menarche: A Prospective Cohort Study in Chilean Girls
Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche
New insights from GWAS on BMI-related growth traits in a longitudinal cohort of admixed children with Native American and European ancestry
Time-specific impact of mono-benzyl phthalate (MBzP) and perfluorooctanoic acid (PFOA) on breast density of a Chilean adolescent Cohort
A comparison of various methods for measuring breast density and breast tissue composition in adolescent girls and women
Assessment of a consensus definition of obesity and metabolic health phenotypes in children at different pubertal stages
Genome-Wide Association Study and Polygenic Risk Scores of Serum DHEAS Levels in a Chilean Children Cohort
Habitual Phytoestrogen Intake is Associated with Breast Composition in Girls at 2 Years after Menarche Onset
Higher prepubertal IGF-1 concentrations associate to earlier pubertal tempo in both sexes
Sugar-sweetened beverage consumption and breast composition in a longitudinal study of Chilean girls
The association of age at menarche and adult height with mammographic density in the International Consortium of Mammographic Density
Variability in urinary phthalates, phenols, and parabens across childhood and relation to adolescent breast composition in Chilean girls
Association between obesity with pattern and length of menstrual cycle: The role of metabolic and hormonal markers.
Exposure to obesogenic endocrine disrupting chemicals and obesity among youth of Latino or Hispanic origin in the United States and Latin America: A lifecourse perspective
High DHEAS in girls and metabolic features throughout pubertal maturation
Novel loci and mapuche genetic ancestry are associated with pubertal growth traits in Chilean boys
The Association Between Breast Density and Gut Microbiota Composition at 2 Years Post-Menarche: A Cross-Sectional Study of Adolescents in Santiago, Chile
Total and central adiposity are associated with age at gonadarche and incidence of precocious gonadarche in boys.
A Polygenic Risk Score Suggests Shared Genetic Architecture of Voice Break With Early Markers of Pubertal Onset in Boys
Association between indicators of systemic inflammation biomarkers during puberty with breast density and onset of menarche
Childhood Obesity: A Risk Factor for Non-alcoholic Fatty Liver Disease in Adolescence
Early Obesity: Risk Factor for Fatty Liver Disease
Effect of excessive gestational weight on daughters' breast density at the end of puberty onset
High DHEAS Level in Girls Is Associated with Earlier Pubertal Maturation and Mild Increase in Androgens throughout Puberty without Affecting Postmenarche Ovarian Morphology
Reproductive hormones during pubertal transition in girls with transient Thelarche
Age at Pubertal Development in a Hispanic-Latina Female Population: Should the Definitions Be Revisited?
Identification and functional analysis of missense mutations in the lecithin cholesterol acyltransferase gene in a Chilean patient with hypoalphalipoproteinemia
Obesity and Related Metabolic Biomarkers and Its Association with Serum Levels of Estrogen in Pre-pubertal Chilean Girls
Role of the Androgen Receptor Gene CAG Repeat Polymorphism on the Sequence of Pubertal Events and Adiposity in Girls with High Dehydroepiandrosterone Sulfate Level
Childhood and adolescent phenol and phthalate exposure and the age of menarche in Latina girls
Effectiveness of breast cancer screening policies in countries with medium-low incidence rates
Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls
Female offspring birth weight is associated with Body Mass Index, waist circumference and metabolic syndrome in Latin American women at 10-years postpartum
Inverse association between estrogen receptor-alpha DNA methylation and breast composition in adolescent Chilean girls
Precocious pubertal events in Chilean children: ethnic disparities
Prepubertal and Pubertal Endocrine-Disrupting Chemical Exposure and Breast Density among Chilean Adolescents
Dairy intake in relation to breast and pubertal development in Chilean girls.
Determinants of volumetric breast density in Chilean premenopausal women.
Early BMI Gain and Later Height Growth Predicts Higher DHEAS Concentrations in 7-Year-Old Chilean Children
Early BMI Gain and Later Height Growth Predicts Higher DHEAS Concentrations in 7-Year-Old Chilean Children.
Genetic Variation of Follicle-Stimulating Hormone Action Is Associated With Age at Testicular Growth in Boys.
High DHEAS Is Associated With Earlier Pubertal Events in Girls But Not in Boys
Mammographic Density and Ageing: A Collaborative Pooled Analysis of Cross-Sectional Data From 22 Countries Worldwide
Mammographic density and ageing=> A collaborative pooled analysis of cross-sectional data from 22 countries worldwide.
Metabolic Syndrome and Mammographic Density in Premenopausal Chilean Women.
International Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries
Mammographic density assessed on paired raw and processed digital images and on paired screen-film and digital images across three mammography systems.
Ultrasensitive estrogen levels at 7 years of age predict earlier thelarche: evidence from girls of the growth and obesity Chilean cohort
Breast bud detection: a validation study in the Chilean Growth Obesity Cohort Study
Early adiposity rebound is associated with metabolic risk in 7-year-old children
Country-level correlates of cervical cancer mortality in Latin America and the Caribbean.
Hypertension and the Risk of Breast Cancer in Chilean Women: a Case-control Study
Cervical Cancer Screening Programs in Latin America and the Caribbean
Present situation of hepatitis B in Chile
Situación actual de la hepatitis B en Chile
Relation between insulin resistance and breast cancer among Chilean women
Percepción de conductas abisivas en estudiantes de medicina
Perception of abuse among medical students of the University of Chile
Early detection of diabetic nephropathy in children and adolescents with type 1 diabetes mellitus
Pesquiza precoz de nefropatía diabética en niños y adolescentes portadores de diabetes mellitus tipo 1
A report on student abuse during medical training

Abstract (5)

High DHEAS (HD) in Girls Determines Earlier Pubertal Maturation and Mild Hyperandrogenism Throughout Pubertal Development
OBESITY AND ESTROGEN LEVELS IN PRE-PUBERTAL GIRLS PARTICIPANTS IN THE GROWTH AND OBESITY CHILEAN STUDY
ASSOCIATION BETWEEN METABOLIC SYNDROME AND BREAST DENSITY IN PREMENOPAUSAL CHILEAN WOMEN
EXCESS WEIGHT AND BREAST DENSITY AT PUBERTY, AN UNKNOWN ASSOCIATION: EVIDENCE FROM THE GROWTH AND OBESITY CHILEAN COHORT
EVALUATION OF THE NATIONAL CERVICAL SCREENING PROGRAMME IN CHILE

ConferencePaper (30)

Association between obesity and precocious puberty in Chilean boys
Elevated concentrations of DHEAS at 7 years are associated with increased glycemia during puberty but not with metabolic syndrome
Are Ultrasensitive Estrogens Levels in Pre-pubertal Girls Associated with Breast Composition at the End of Puberty?
Critical windows for prevention of obesity and associated conditions: the GOCS and CHIMINO chilean cohorts.
Early determinants of breast cancer. Breast density: a predictor of risk.
Effect of excessive gestational weight gain during pregnancy on daughter’s breast density at the end of puberty onset
High DHEAS at age 7 are associated to higher glycemia during puberty but not metabolic syndrome
Lower AMH Concentrations and High Androgens in Girls with Premature Adrenarche at Pubertal Onset
Onset of pubertal development in Chilean children: ethnic differences
Premature adrenarche and low AMH levels at the onset of puberty
Premature adrenarche and metabolic risk: differences by gender
Pubertal Onset in Boys is Influenced by BMI and Genetic Variation of Fshb and Fshr: A Study in Two Population-Based Cohorts of Different Genetic Ancestry
Pubertal Onset in Chilean Children: Ethnic Disparities
Repetitions of the Androgen receptor CAG in girls with early adrenarche: correlation with X-chromosome inactivation and pubertal events
Diet Assessment in Low-to-middle income adolescents from a developing country: lessons from the Chilean Growth and Obesity Cohort Study (GOCS).
Early growth and breast-tissue composition at the end of breast development: exploring the pathways to breast cancer risk in prepubertal girls
Is childhood adiposity related to early pubertal onset in Chilean girls from low-middle socioeconomic level?
Adiposity and pre-pubertal levels in girls participating in the Chilean study of growth and obesity
Adiposity and mammographic breast density in premenopausal Chilean women.
Advanced thelarche in Chilean girls of medium-low socioeconomic status
Are mothers able to detect their daughter’s breast bud? Validation Study in the GOCS cohort
Breast Development at different breast tanner stages: evidence from the growth obesity Chilean cohort study.
Dual X-Ray Absorptiometry an alternative method to measure volumetric breast density
Rapid BMI Growth Followed by Height Increase Predicts High DHEAS in 7y old Chilean Children
Obesity and premenopausal breast cancer risk: role of the oligo-ovulation and endogenous hormones
Life course obesity and premature thelarche in Chilean girls
Validity of Tanner 2 assessment in low-income Chilean mothers
Insulin resistance is associated with breast cancer in chilean women only after menopause
Is recommendable the consumption of fruits and vegetables for preventing breast cancer in Chilean women?
Metabolic syndrome increases the risk of breast cancer in postmenopausal women

ConferencePoster (5)

Association between indicators of adiposity during childhood and age of menarche in Chilean adolescents
Androgen receptor gene cag repeat polymorphism in girls with high dheas: association with pubertal events and body composition
Development of a new tool for dietary data collection: SER-24h, software for 24 hours recall
Previous step to analyze 24-h dietary recalls: standardization of the food composition database for the “growth and obesity cohort study”
Premature adrenarche in girls at pubertal onset is associated with high androgens, but lower AMH concentrations

Proyecto (19)

Consumption of Ultra-Processed foods and breast density: differences during the life-course.
Cross-Border Approaches to Applying Novel Methods for Child Obesity Research
Effects of the COVID-19 pandemic on diet and mental health in critical stages of life
NOVEL BIOMARKERS, LIPIDOMICS, GENETICS AND INTESTINAL MICROBIOTA IN OBESE ADOLESCENTS WITH FATTY LIVER DISEASE IN NORTH, CENTER AND SOUTH OF CHILE
Association between maternal metabolic disturbances during the first pregnancy and breast density
Premature adrenarche , unanswered questions
Dietary Patterns Associated with Changes in Adiposity and Metabolic Condition at 3 Key Sensitive Periods of Early Life: Infancy, Adiposity Rebound, and Late Puberty
Collaboration network INTA, U of Chile- University California San Francisco for the strengthening of research in the area of ​​early determinants of breast composition in adolescence
Estrogens exposures at the end of puberty influences female breast composition 4 years after menarche. Evidence from the growth and obesity chilean cohort study
Fatty liver disease and its relationship with metabolic syndrome, genetics and intestinal microbiota in school age Chilean children
Multivariate models for genome-wide association studies in admixed populations
Environmental chemicals and postpubertal breast composition in a Latino cohort
PREMATURE ANDRENARCHE AND EFFECTS ON OVARIAN FUNCTION, PUBERTAL TEMPO AND METABOLIC RISK
ARE ULTRASENSITIVE ESTROGEN LEVELS ASSOCIATED WITH PUTATIVE EARLY MARKERS OF BREAST CANCER RISK? EVIDENCE FROM PRE- PUBERTAL CHILEAN GIRLS
EARLY GROWTH AND BREAST-TISSUE COMPOSITION AT THE END OF BREAST DEVELOPMENT=> DISENTANGLING THE PATHWAYS TO BREAST CANCER RISK IN CHILEAN GIRLS
Early Determinants of Breast Cancer Risk
Determinants of breast cancer risk in premenopausal Chilean women
An Evaluation of the National Cervical Cancer Screening Programme in Chile
Association between obesity and insulin resistance with breast cancer in Chilean women

Review (1)

Environmental exposures during windows of susceptibility for breast cancer: a framework for prevention research
109
Ana Pereira

Assistant Professor

Institute of Nutrition and Food Technology (INTA)

Santiago, Chile

27
Camila Corvalan

Assistant Professor

UNIVERSIDAD DE CHILE, INTA

SANTIAGO, Chile

13
Maria Mericq

Profesor Titular

IDIMI

Universidad de Chile

Santiago, Chile

10
Maria Garmendia

Academic

Institute of Nutrition and Food Technology (INTA)

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

5
JOSE SANTOS

Full Professor

Department of Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

4
JOSE MIRANDA

Estudiante de Doctorado

Nutrición, Diabetes y Metabolismo

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Marcela Reyes

Profesor Asistente

INSTITUTO DE NUTRICIÓN Y TECNOLOGÍA DE LOS ALIMENTOS (INTA)

Santiago, Chile

2
Juliana Kain

Profesor Asociado

INTA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

2
Susana Eyheramendy

Full Professor

Universidad Adolfo Ibánez

Santiago, Chile

1
Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - ESCUELA DE MEDICINA - DEPTO DE GASTROENTEROLOGÍA

Santiago, Chile

1
Alvaro Martínez

Director Asociado de Propiedad Intelectual y Transferencia Tecnológica

FUNDACIÓN CIENCIA PARA LA VIDA (FCV)

Santiago, Chile

1
Juan Gana

Gastroenterólogo Pediatra

Departamento de Gastroenterología y Nutrición Pediátrica.

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

1
Maria Alvarado

Académico

Escuela Salud Pública

Universidad de Chile

Santiago, Chile

1
Gigliola Alberti

profesora asistente

gastroenterologia y nutricion pediatrica

pontificia universidad católica de chile

santiago, Chile

1
Tomás Norambuena

Group Lead del equipo de Data Science y Bioinformática

Data Science y Bioinformática

Meristem SpA

Santiago, Chile

1
valentina serrano

PROFESOR ASISTENTE

NUTRICION, DIABETES Y METABOLISMO

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Mariana Cifuentes

Professor

Instituto de Nutricion y Tecnologia de los Alimentos

INTA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Joanna Rojas

Académica

Nutrición y Dietética

Universidad de Atacama

Copiapó, Chile