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Paula Ivonne Rodas Garrido

Microbiology Consultant

Pan American Health Organization (PAHO - OPS/OMS Chile)

Vitacura, Chile

Pathogenesis of Neisseria gonorrhoeae in the female genital tract. Genital microbiota and its influence in sexually-transmitted infections (STIs) Antimicrobial resistance and virulence/pathogenesis in Healthcare associated infections (HAIs)

Bachelor, Universidad de Chile. Chile, 2003
Biochemist, Universidad de Chile. Chile, 2005
Ph.D, Universidad de Chile. Chile, 2012

Instructor Part Time

Universidad de Santiago de Chile

Chemistry and Biology

Santiago, Chile

2011 - 2012
Assistant Professor Full Time

Universidad Andrés Bello

Medicine

Santiago, Chile

2012 - 2017
Postdoctoral Fellow Part Time

University of Southampton

Medicine

Southampton, Reino Unido

2012 - 2013
Principal Investigator /Assistant Professor Full Time

UNIVERSIDAD ANDRES BELLO

Medicine

Concepción, Chile

2018 - 2019
Research Associate Full Time

UNIVERSIDAD MAYOR

CIENCIAS

Santiago, Chile

2019 - 2021

Research Assistant Full Time

FONDAP-Centro de Estudios Moleculares de la Célula- Facultad de Medicina, Universidad de Chile

Santiago, Chile

2005 - 2006
Principal investigator REDI170370 grant Other

PCI-CONICYT

Chile

2018 - 2019
Principal Investigator FONDECYT 11121262 Other

FONDECYT

Chile

2013 - 2016
Postdoctoral Fellow WT090301 Full Time

Wellcome Trust

Southampton, Reino Unido

2012 - 2013
Visiting Professor Other

Julius-Maximilians-Universität Würzburg

Alemania

2014 - 2014
Microbiology consultant Full Time

Pan American Health Organization (PAHO-Chile)

Santiago, Chile

2021 - A la fecha

Thesis supervision:

- Master in Biochemistry: 1
- Master in Biotechnology: 2
- Internships: 20

National Doctorate Fellowship

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2006

Fellowship to obtain a Ph.D degree in the University of Chile
Travel Grant GDEST

Ministerio da Ciencia e Tecnologia do Brasil

Brasil, 2006

Travel grant to attend the Global Dialogues on Emerging Science An Technology (GDEST) - Conference on Bioinformatics Funded by Ministerio da Ciencia e Tecnologia do Brasil and The Office of the Science and Technology Adviser to the Secretary of States - USA
Grant for development of Doctoral Thesis

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2008

Grant for funding consumables and reagents in doctoral thesis
Global Health Travel Award

BILL AND MELINDA GATES FOUNDATION

Estados Unidos, 2008

Travel grant to fund attendance to the conference D4: Molecular Evolution as a Driving Force in Infectious Diseases Meeting (Keystone Symposia Global Health Series). 08-13 April 2008, Breckenridge (CO), USA.
Youth Travel Fellowship

Federation of European Biochemical Societies (FEBS)

Reino Unido, 2010

Travel grant to fund the attendance to the EMBO/FEBS Lecture Course 2010 ‘Host-Microbes Interactions’. 01-09 September 2010, Island of Spetses, Greece.
Oriana Josseau Award

Oriana Josseau Foundation

Chile, 2010

Award to the 2010 best female student of the Ph.D of Biochemistry Program, Faculty of Chemical Sciences, University of Chile


Macrophage-Neisseria gonorrhoeae Interactions: A Better Understanding of Pathogen Mechanisms of Immunomodulation Escobar, Alejandro; Rodas, Paula I; Acuna-Castillo, Claudio Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2018)
Microbiological characterisation of the colonisation by Candida sp in patients with orthodontic fixed appliances and evaluation of host responses in saliva Tapia, Cecilia V.; Batarce, Christian; Amaro, José; Hermosilla, Germán; Rodas, Paula I; Magne, Fabien Article WOS Scopus (2018)
Protective effect of inactivated blastoconidia in keratinocytes and human reconstituted epithelium against C. albicans infection Alburquenque, Claudio; Amaro, José; Fuentes, Marisol; Falconer, Mary A.; Moreno, Claudia; Covarrubias, Cristián; Pinto, Cristián; Rodas, Paula I; Bucarey, Sergio A.; Hermosilla, Germán; Magne, Fabien; Tapia, Cecilia V. Article Scopus, WOS Medical Mycology (2018)
Differential Antifungal Activity of Human and Cryptococcal Melanins with Structural Discrepancies Correa, Néstor; Covarrubias, Cristián; Rodas, Paula I; Hermosilla, Germán; Olate, Verónica R; Valdés, Cristián; Meyer, Wieland; Magne, Fabien; Tapia, Cecilia V Article Frontiers in Microbiology (2017)
Genotyping and Persistence of Candida albicans from Pregnant Women with Vulvovaginal Candidiasis Tapia, Cecilia V; Hermosilla, Germán; Fortes, Paula; Alburquenque, Claudio; Bucarey, Sergio; Salinas, Horacio; Rodas, Paula I; Díaz, Maria C; Magne, Fabien Article MYCOPATHOLOGIA (2017)
Modified profile of matrix metalloproteinase-2 and -9 production by human Fallopian tube epithelial cells following infection in vitro with Neisseria gonorrhoeae Rodas, Paula I; Pérez, Doris; Jafrett, Claudia; González, Yaquelin; Carreño, Carolina; Tapia, Cecilia V; Osorio, Eduardo; Velásquez, Luis A; Christodoulides, Myron Article JOURNAL OF INFECTIOUS DISEASES (2017)
Neisseria gonorrhoeae Challenge Increases Matrix Metalloproteinase-8 Expression in Fallopian Tube Explants Juica, Natalia E.; Rodas, Paula I.; Solar, Paula; Borda, Paula; Vargas, Renato; Muñoz, Cristobal; Paredes, Rodolfo; Christodoulides, Myron; Velasquez, Luis A. Article ISI SCOPUS Frontiers in Cellular and Infection Microbiology (2017)
A feed-forward loop between SroC and MgrR small RNAs modulates the expression of eptB and the susceptibility to polymyxin B in Salmonella Typhimurium Lillian G. Acuña; M. José Barrios; Diego Peñaloza; Paula I. Rodas; Daniel Paredes-Sabja; Juan A. Fuentes; Fernando Gil; Iván L. Calderón Article Microbiology (2016)
A feed-forward loop between SroC and MgrR small RNAs modulates the expression of eptB and the susceptibility to polymyxin B in Salmonella Typhimurium Acuña, Lilian G; Barros, M José; Peñaloza, Diego; Rodas, Paula I; Paredes-Sabja, Daniel; Fuentes, Juan A; Gil, Fernando; Calderón, Iván L Article MICROBIOLOGY-SGM (2016)
ATP Induces IL-1b Secretion in Neisseria gonorrhoeae-Infected Human Macrophages by a Mechanism Not Related to the NLRP3/ASC/Caspase-1 Axis García, Killen; Escobar, Giselle; Mendoza, Pablo; Beltrán, Caroll; Pérez, Claudio; Arancibia, Sergio; Vernal, Rolando; Rodas, Paula I; Acuña-Castillo, Claudio; Escobar, Alejandro Article MEDIATORS OF INFLAMMATION (2016)
Characterization of the adherence of Clostridium difficile spores: The integrity of the outermost layer affects adherence properties of spores of the epidemic strain R20291 to components of the intestinal mucosa Mora-Uribe, Paola; Miranda-Cárdenas, Camila; Castro-Córdova, Pablo; Gil, Fernando; Calderón, Iván L.; Fuentes, Juan A.; Rodas, Paula I.; Banawas, Saeed; Sarker, Mahfuzur R.; Paredes-Sabja, Daniel Article Frontiers in Cellular and Infection Microbiology (2016)
Increased PD-L1 expression and PD-L1/CD86 ratio on macrophages infected with Neisseria gonorrhoeae contributes to the functional suppression of T-cell responses M. Carolina Ortiz; Claudio Acuña-Castillo; Rodolfo Vernal; Mónica Imarai; Paula I. Rodas; Alejandro Escobar Article Frontiers in Immunology (2016)
Influence of the carbon sources mannose and galactose in the physicochemical and biological properties of silver nanoparticles produced by Aspergillus niger Pablo I. González; Cristián Vilos; Cecilia V. Tapia; Juan A. Fuentes; Fernando Gil; Iván L. Calderón; Daniel Paredes-Sabja; Paula I. Rodas Article Applied Microbiology and Biotechnology (2016)
Lose to win=> marT pseudogenization in Salmonella enterica serovar Typhi contributed to the surV-dependent survival to H2O2, and inside human macrophage-like cells Ortega, Alison P; Villagra, Nicolás V; Urrutia, Italo M; Valenzuela, Luis M; Talamilla-Espinoza, Andrea; Hidalgo, Alejandro A; Rodas, Paula I; Gil, Fernando; Calderón Iván L, Paredes-Sabja; Daniel, Mora; Guido C, Fuentes Article INFECTION GENETICS AND EVOLUTION (2016)
Salmonella Typhimurium exhibits fluoroquinolone resistance mediated by the accumulation of the antioxidant molecule H2S in a CysK-dependent manner Frávega, Jorge; Álvarez, Ricardo; Díaz, Fernando; Inostroza, Osvaldo; Tejías, Cristóbal; Rodas, Paula I; Paredes-Sabja, Daniel; Fuentes, Juan A; Gil, Fernando Article JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2016)
The NarE protein of Neisseria gonorrhoeae catalyzes the ADP-ribosylation of several ADP-ribose acceptors despite a N-terminus deletion Paula I. Rodas; A. Said Álamos-Musre; Francisca P. Alvarez; Alejandro Escobar; Cecilia V. Tapia; Carolina Otero; Iván L. Calderón; Juan A. Fuentes; Daniel Paredes-Sabja; Myron Christodoulides Article FEMS MICROBIOLOGY LETTERS (2016)
Motility modulation by the small non-coding RNA SroC in Salmonella Typhimurium Fuentes, Daniela N; Calderón, Paulina F; Acuña, Lilian G; Rodas, Paula I; Paredes-Sabja, Daniel; Fuentes, Juan A; Gil, Fernando; Calderón, Iván L Article FEMS MICROBIOLOGY LETTERS (2015)
Neisseria gonorrhoeae Modulates Immunity by Polarizing Human Macrophages to a M2 Profile Ortiz, M Carolina; Lefimil, Claudia; Rodas, Paula I; Vernal, Rodolfo; López, Mercedes; Acuña-Castillo, Claudio; Imarai, Mónica; Escobar, Alejandro Article PLoS One (2015)
Participation of S. Typhimurium cysJIH operon in the H2S-mediated ciprofloxacin resistance in presence of sulfate as sulfur source Ricardo Álvarez; José Frávega; Paula I. Rodas; Juan A. Fuentes; Daniel Paredes-Sabja; Iván L. Calderón; Fernando Gil Article Antibiotics (2015)
Preclinical Development and In Vivo Efficacy of Ceftiofur-PLGA Microparticles Vilos, Cristián; Velásquez, Luis A; Rodas, Paula I; Zepeda, Katherine; Bong, Song-J; Herrera, Natalia; Cantín, Mario; Simón, Felipe; Constandil, Luis Article PLoS One (2015)
Evaluation of ceftiofur–PHBV microparticles in rats Cristian Vilos; Luis Constandil; Paula I. Rodas; Mario Cantin; Katherine Zepeda; Natalia Herrera; Luis A. Velasquez Article Drug Design, Development and Therapy (2014)
Temporal and spatial regulation of cAMP signaling in disease=> role of cyclic nucleotide phosphodiesterases Otero, Carolina; Peñaloza, Juan P; Rodas, Paula I; Fernández-Ramires, Ricardo; Velásquez, Luis; Jung, Juan E Article FUNDAMENTAL & CLINICAL PHARMACOLOGY (2014)
Neisseria gonorrhoeae pilus attenuates cytokine response of human Fallopian tube explants Velásquez,Luis A; García,Katherine; Morales,Francisco; Heckels,John E. ; Rodas,Paula I.; Christodoulides, Myron; Hugo Cárdenas Article Journal of Biomedicine and Biotechnology (2012)
A holin remnant protein encoded by STY1365 is involved in envelope stability of Salmonella enterica serovar Typhi Rodas, Paula I.; Trombert, A. Nicole; Guido C. Mora Article FEMS Microbiological Letters (2011)
Reduced invasion to human epithelial cell lines of Salmonella enterica serovar Typhi carrying S. Typhimurium sopD2 Trombert, A Nicole; Rodas, Paula I; Mora, Guido C Article FEMS MICROBIOLOGY LETTERS (2011)
Salmonella enterica serovar Typhi has a 4.1 kb genetic island inserted within the sapABCDF operon that causes loss of resistance to the antimicrobial peptide protamine Paula I. Rodas; Ines Contreras; Inés Contreras; Guido C. Mora Article Journal of Antimicrobial Chemotherapy (2010)
Precise excision of the large pathogenicity island, SP17, in Salmonella enterica serovar Typhi Bueno, SM; Santiviago, CA; Murillo, AA; Fuentes, JA; Trombert, AN; Rodas, PI; Youderian, P; Mora, GC Article JOURNAL OF BACTERIOLOGY (2004)


Use of Human Fallopian Tube Organ in Culture (FTOC) and Primary Fallopian Tube Epithelial Cells (FTEC) to Study the Biology of Neisseria gonorrhoeae Infection. Alamos-Musre, A. Said; Escobar, Alejandro F.; Tapia, Cecilia V.; Christodoulides, Myron; Rodas, Paula I BookSection (2019)
Use of Human Monocyte-Derived Macrophages to Study Neisseria Gonorrhoeae Infection Gatica J.; Rodas, Paula I; Escobar, Alejandro F. BookSection (2019)


Use of Human Fallopian Tube Organ in Culture (FTOC) and Primary Fallopian Tube Epithelial Cells (FTEC) to Study the Biology of Neisseria gonorrhoeae Infection Álamos-Musre A.S.; Escobar A.; Tapia C.V.; Christodoulides M.; Rodas P.I. BookWhole ISI SCOPUS NEISSERIA MENINGITIDIS (2019)