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Antonio Alejandro Eblen Zajjur

Académico Investigador Senior

Universidad Autónoma de Chile

Santiago, Chile

Human spinal cord fNIRS Neuronal networks: spinal cord and sensory ganglia Pain endogenous modulation systems Spinal dorsal horn Neurochemistry Nociceptive sensory coding Brain edema Functional Cortical Connectivity Medical devices

Médico Cirujano, Universidad de Carabobo. Venezuela, 1986
Neurofisiología, Universidad de Heidelberg. Alemania, 1993

Investigador Postdoctoral Full Time

Instituto Venezolano de Investigaciones Científicas

Centro de Biofísica y Bioquímica

Caracas, Venezuela

1993 - 1995
Profesor Titular Full Time

Universidad de Carabobo

Ciencias de la Salud

Valencia, Venezuela

1995 - 2016
Profesor Adjunto Part Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ingeniería, Ciencias Biologícas, Medicina

Santiago, Chile

2017 - A la fecha
Director Postgraduate School Full Time

Universidad Diego Portales

Facultad de Medicina

Santiago, Chile

2020 - 2024
Senior Researcher Full Time

Universidad Autonoma de Chile

Ciencias de la Salud

Santiago, Chile

2024 - A la fecha

Investigador Postdoctoral Full Time

Instituto Venezolano de Investigaciones Científicas, IVIC.

Caracas, Venezuela

1993 - 1995
Profesor Titular Full Time

Universidad de Carabobo

Valencia, Venezuela

1995 - 2016
Director de Investigación Facultad de Ciencias de la Salud Full Time

Universidad de Carabobo

Valencia, Chile

2004 - 2006
Decano Facultad de Ciencias de la Salud Full Time

Universidad de Carabobo

Valencia, Chile

2006 - 2009
Director de Postgrado Full Time

Universidad Diego Portales, facultad de Medicina

Santiago, Chile

2020 - 2024
Académico Investigador Senior Full Time

Universidad Autonoma de Chile

Santiago, Chile

2024 - A la fecha

Thesis in the last 3 years (& level):

Undergraduate:
Medicine: 1
Biology: 1

Postgraduate:
Medical Specialties: 5
Magister: 1
PhD: 6
Postdocs: 2

Padrino de la LXII Promoción de Médicos Cirujanos 2016, Ciudad Hospitalaria Dr. Enrique Tejera.

Universidad de Carabobo

Venezuela, 2016

Reconocimiento al Profesor mas destacado durante la Generación.
Padrino de la LXI Promoción de Médicos Cirujanos 2015, Hospital Universitario Dr. Ángel Larralde

Universidad de Carabobo.

Venezuela, 2015

Profesor mas destacado de la generación
Premio al mejor Trabajo Especial de Grado TSU Cardiopulmonar 2012, por el Trabajo (Tutor

Universidad de Carabobo

Venezuela, 2012

Tutor del mejor Trabajo especial de grado
Padrino de la V Promoción de Técnicos Superiorres Universitarios Cardiopulmonares, 2014, Escuela de Ciencias Biomédicas y Tecnológicas

Universidad de Carabobo

Venezuela, 2014

Profesor mas destacado de la Generación.
Padrino de la LVII Promoción de Médicos Cirujanos 2012, Ciudad Hospitalaria Dr. Enrique Tejera

Universidad de Carabobo

Venezuela, 2012

Profesor mas destacado de la generación
Premio "Miguel Pérez Carreño, 2.011", Colegio de Médicos del Edo. Carabobo por el Trabajo (Tutor)

Colegio de Médicos del Estado Carabobo

Venezuela, 2011

Premio anual al mejor trabajo científico.
Premio “Dr. Francisco Javier Triana Alonso” en su segunda Clase

Universidad de Carabobo

Venezuela, 2010

Premio a la investigación científica universitaria
Honor al Mérito Académico, Colegio de Médicos del Edo. Carabobo

Colegio de Médicos del Estado Carabobo

Venezuela, 1999

Honor al Mérito científico anual
Medalla Centenaria, Academia Nacional de Medicina, Venezuela, 2.008

Academia Nacional de Medicina, Venezuela

Venezuela, 2008

Mérito científico nacional.
Medalla Cincuentenaria, Universidad de Carabobo, 2.008

Universidad de Carabobo

Venezuela, 2008

Mérito científico
Orden Ciudad de Valencia, Edo. Carabobo, Primera Clase, 2008

Municipalidad de Valencia

Venezuela, 2008

Méritos científicos y ciudadanos
Premio Nacional EUREKA a la innovación (Tutor)

Ministerio de Ciencia, Tecnología e Innovación.

Venezuela, 2008

Premio a la innovación tecnológica, diseño de equipo para potenciales evocados medulares.


Comparison of LED- and LASER-based fNIRS technologies to record the human peri-spinal cord neurovascular response Caulier-Cisterna, Raill; Appelgren-Gonzales, Juan -Pablo; Oyarzun, Juan -Esteban; Valenzuela, Felipe; Sitaram, Ranganatha; Eblen-Zajjur, Antonio; Uribe, Sergio Article ISI MEDICAL ENGINEERING & PHYSICS (2024)
Peri-spinal Neurovascular Response Triggered by a Painless Electrical Nerve Stimulation in Patients with Chronic Arterial Hypertension Appelgren, Juan Pablo Gonzalez; Uribe, Sergio Article ISI JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING (2023)
Peri-spinal Neurovascular Response Triggered by a Painless Electrical Nerve Stimulation in Patients with Chronic Arterial Hypertension. Raul Caulier-Cisterna; Juan Oyarzun; Sergio Uribe; Antonio Eblen Zajjur Article WOS JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING (2023)
Case report: Long-term follow-up of a large full-thickness skin defect treated with a photosynthetic scaffold for dermal regeneration Carvajal, Felipe; San Martin, Sebastian Article ISI FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2022)
Case report: Long-term follow-up of a large full-thickness skin defect treated with a photosynthetic scaffold for dermal regeneration. Obai Article WOS FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2022)
Detection of autism spectrum disorders using the questionnaire M-CHAT R / F: The importance of considering socio-cultural and language aspects Detección de trastornos del espectro autista mediante el cuestionario M-CHAT R/F: necesidad de considerar aspectos socio-culturales y de lenguaje Dominique, Martí C.; Waldo, Aranda; Eblen-Zajjur, Antonio Article SCOPUS Archivos de Neurociencias (2022)
Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report Pablo Gonzalez-Appelgren, Juan; Gonzalez, Leticia; Trujillo, Oscar; Uribe, Sergio Article ISI BMC NEUROLOGY (2022)
Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report. Oyarzun, JE; Trujillo, Oscar; Antonio Eblen-Zajjur; Sergio Uribe A. Article WOS, Scopus BMC NEUROLOGY (2022)
Recording of the spinal neurovascular response triggered by a non-noxious peripheral nerve stimulation in patients with diabetes mellitus Oyarzun, Juan E.; Caulier Cisterna, Raul; Appelgren, Juan Pablo Gonzalez; Eblen-Zajjur, Antonio; URIBE-ARANCIBIA, SERGIO ANDRES Article ISI METABOLISM-CLINICAL AND EXPERIMENTAL (2022)
Recording of the spinal neurovascular response triggered by a non-noxious peripheral nerve stimulation in patients with diabetes mellitus. Juan E Oyarzun; Raul Caulier-Cisterna; Antonio Eblen-Zajjur; Sergio Uribe A. Article WOS, Scopus METABOLISM-CLINICAL AND EXPERIMENTAL (2022)
A First in Human Trial Implanting Microalgae Shows Safety of Photosynthetic Therapy for the Effective Treatment of Full Thickness Skin Wounds Obaid, Miguel Luis; Camacho, Juan Pablo; Brenet, Marianne; Corrales-Orovio, Rocio; Carvajal, Felipe; Martorell, Ximena; Werner, Consuelo; Simon, Valeska; Varas, Juan; Calderon, Wilfredo; et al. Article ISI FRONTIERS IN MEDICINE (2021)
Detección de trastornos del espectro autista mediante el cuestionario M-CHAT R/F: Necesidad de considerar la socio-cultura y el lenguaje Martí-Courvis D; Aranda Waldo Article Scopus ARCHIVOS DE NEUROCIENCIAS (2021)
Epileptic Signal Detection Using Quilted Synchrosqueezing Transform Based Convolutional Neural Networks Villazana, Sergio; Montilla, Guillermo; Maldonado, Carlos Article ISI Computación y Sistemas (2021)
Non-invasive functional evaluation of the human spinal cord by assessing the Peri-spinal neurovascular network with near infrared spectroscopy Mohit Rana; Ranganatha Sitaram; Sergio Uribe A.; Antonio Eblen Article WOS, Scopus. IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING (2021)
Coronary blood flow measurement in conventional coronary angiograms by a new method based on contrast density detection. A physiologic Insight Miguel Lopez-Hidalgo; Antonio Eblen-Zajjur Article WOS ARQUIVOS BRASILEIROS DE CARDIOLOGIA (2020)
Coronary Blood Flow Measurement in Conventional Coronary Angiograms by a New Method Based on Contrast Density Detection. A Physiological Insight Lopez-Hidalgo, Miguel Article ISI ARQUIVOS BRASILEIROS DE CARDIOLOGIA (2020)
Isquemia miocárdica con coronarias de aspecto angiográfico normal. Enfoque diagnóstico Miguel Lopez-Hidalgo; Antonio Eblen-Zajjur Article SCOPUS INVESTIGACION CLINICA (2020)
Myocardial ischemia and coronary arteries with normal angiographic appearance. Diagnostic approach. Lopez-Hidalgo, Miguel; Eblen-Zajjur, Antonio Article ISI SCOPUS INVESTIGACION CLINICA (2020)
Spikes and Nets (S&N): A New Fast, Parallel Computing, Point Process Software for Multineuronal Discharge and Connectivity Analysis Valle, Carlos Article ISI NEURAL PROCESSING LETTERS (2020)
Acute Cardiovascular Responses to a Session of Bikram Yoga: A Pilot Uncontrolled Trial Miranda Hurtado, Martin; Meza Valladares, Cristian; Eblen-Zajjur, Antonio Article ISI SCOPUS JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2019)
Administration of memantine reverses behavioral, histological, and electrophysiological abnormalities in rats subjected to early maternal deprivation Nayadoleni N. Article ISI SCOPUS JOURNAL OF NEURAL TRANSMISSION (2019)
Age related T2-FSE-MRI basal ganglia and inter-nuclei changes in normal aging Article SCOPUS Neurology Psychiatry and Brain Research (2019)
Enfoque terapéutico del paciente con isquemia miocárdica y arterias coronarias de aspecto normal. Miguel Lopez-Hidalgo; Antonio Eblen-Zajjur Article SCOPUS AVANCES EN CARDIOLOGIA (2019)
Enoxaparin pretreatment effect on local and systemic inflammation biomarkers in the animal burn model Crespo, G Article ISI INFLAMMOPHARMACOLOGY (2019)
Genotypic expression of CYP3A4 in workers exposed to inhibitor pesticides of the colinesterase, Venezuela Antonio Eblen-Zajjur Article Scopus Revista Mexicana Patologia Clinica Medica Laboratorial (2019)
Myocardial Monophasic Action Potential Recorded by Suction Electrode for Ionic Current Studies in Zebrafish Miranda, Miguel Article ISI SCOPUS ZEBRAFISH (2019)
Salud y Enfermedad Mental: Del Corpus Hippocraticum a una aproximación termodinámica Article Scopus Revista de Neuro-Psiquiatría (2019)
Tuberculosis enfermedad reemergente. multirresistente. Reporte de un caso Antonio Eblen-Zajjur Article Scopus Comunidad y Salud (2019)
Acute coronary syndrome with coronary arteries without obstructive lesions. Diagnostic therapeutic controversy? Cornejo-Rivas C Article Scielo, Scopus Revista de la Federación Argentina de Cardiología (2018)
Age Related FLAIR-MRI Brain Cortical Changes in Normal Aging: Central Tendency versus Dispersion Values Article Scielo, Scopus Archivos de Neurociencias (2018)
Bioethics in the evaluation of the fetal central nervous system in third world countries: applying Rotary International’s four way test Hernández-Rojas P; García de Yégüez M; Ramos-Piñero M Article Scielo, Scopus Journal of negative and no positive results (2018)
Effects of estradiol or progesterone on principal cells from amygdala complex evaluated in silico Article Scielo, Scopus Archivos Mexicanos de Neurociencias (2018)
Enoxaparin pretreatment effect on local and systemic inflammation biomarkers in the animal burn model Vicci H, Eblen-Zajjur A; López M, Crespo G Article INFLAMMOPHARMACOLOGY (2018)
Evaluación de la actividad de la colinesteras, medio ambiente y geolocalización de trabajadores expuestos en una comunidad agraria de la Colonia Tovar, Venezuela Marrero S; Guevara H; Sequera M Article Scielo, Scopus Revista Latinoamericana de Patología clínica y laboratorio (2018)
In silico evaluation of benzodiacepine, ketamine and temperature effect on pre-Bötzinger neuronal discharge patterns of respiratory control Article Scielo, Scopus Archivos de Neurociencias (2018)
Thermo-dependence of noxious mechanical heterotopic stimulation-dependent modulation of the spinal dorsal horn response to somatosensory stimulation Article ISI, WOS JOURNAL OF INTEGRATIVE NEUROSCIENCE (2018)
Detección de Cambios Abruptos en Señales Epilépticas del EEG usando la Descripción de Datos basados en Vectores de Soporte Article Scielo Archivos de Neurociencias (2017)
Evaluación de la exposición a organo-fosforados y carbamatos en trabajadores de la comunidad agraria Marrero S; Guevara H Article Scielo Comunidad y Salud (2017)
Honor a quien honor merece: Guillermo Wittembury Montoriano R; Soria, A; Parisi, M; Fischbarg G Article Scielo SALUS (2017)
[In silico evaluation of an aviar influenza AH5N1 virus outbreak with human to human transmission=> effects of sanitary measures in Valencia, Venezuela, 2012]. Reggeti, Mariana; Romero, Emilse; Eblen-Zajjur, Antonio Article Revista chilena de infectologiÌ�a => oÌ�rgano oficial de la Sociedad Chilena de InfectologiÌ�a (2016)
Evaluación de parámetros inflamatorios locales y sistémicos de quemadura periférica en un modelo animal Vicci, H. Article Rev Peru Med Exp Salud Publica (2016)
Evaluación in silico de una epidemia de influenza aviar AH5N1 con transmisión humano-humano: efecto de las medidas sanitarias en Valencia, Venezuela Reggeti, M. Article Rev Chil Inf (2016)
Noxious mechanical heterotopic stimulation induces inhibition of the spinal dorsal horn neuronal network: analysis of spinal somatosensory evoked potentials. Meléndez-Gallardo, J. Article Neurological Sciences (2016)
Transference and Counter Transference between Students and Professors: The Role of Gender or Motherhood in this Psychodynamic Phenomenon Wix-Ramos, RJ.; Santaella-Palma, LE.; Deibis, F. Article Ann Psychiatry Ment Health (2016)
Clasificación de señales electroencefalográficas utilizando entrenamiento cruzado de máquinas de vectores de soporte Villazana, S.; Montilla, G.; Seijas, C.; Caralli, A. Article Revista de Ingeniería UC (2015)
Diurnal changes in ouabain-sensitive Na+,K+- atpase activity in the rat spinal dorsal horn Vanegas, H. Article Neurochem J. (2015)
Efecto de la estimulación eléctrica nociva trigeminal bucal de alta frecuencia sobre la médula espinal lumbar evaluado mediante los potenciales evocados en la rata Article ISI, Scopus Arch. Neurocien. (Mex.) (2015)
Trombina mas allá de la coagulación Vicci, H. Article VITAE (2015)
Aging related changes in mixed basal saliva concentration of sodium, potassium and chloride in healthy non medicated humans Navas, H. Article Curr Aging Science (2014)
Drug Treated Schizophrenia, Schizoaffective and Bipolar Disorder Patients Evaluated by qEEG Absolute Spectral Power and Mean Frequency Analysis. Wix-Ramos, Richard; Moreno, Xiomara; Capote, Eduardo; González, Gilbert; Uribe, Ezequiel; Eblen-Zajjur, Antonio Article Clinical psychopharmacology and neuroscience => the official scientific journal of the Korean College of Neuropsychopharmacology (2014)
Nongenomic effect of levothyroxine on the synchronous electrical activity of the spinal dorsal horn in the rat. Storaci, Verónika; Eblen-Zajjur, Antonio Article Somatosensory & motor research (2014)
Mapping of the fluoride resistant acid phosphatase (frap) activity in cervico-thoracic-lumbar spinal dorsal horn in rats Velasco, D. Article Neurochemistry Journal (2013)
Memantine reverses social isolation induced by ketamine in rats Wix-Ramos, J.; Landaeta, J. Article Exp. Neurobiol- (2013)
Salivary [Na+], [K+] and [Cl-] changes induced by combined treatment with Na/K-ATPase (digoxine) and Na/K/2Cl (furosemide) inhibitors in heart congestive failure patients. Navas, H. Article Curr Topics Pharmacol (2013)
Time course of acute neuroprotective effects of lidocaine evaluated by brain impedanciometry in the global ischemia model. Wix-Ramos, R; Eblen-Zajjur, A Article Pharmacology (2011)
Time course of acute neuroprotective effects of lithium carbonate evaluated by brain impedanciometry in the global ischemia model Article ISI, Scopus Can J. Physiol. Pharmacol (2011)
Cardiovascular drugs in human mechanical nociception=> digoxin, amlodipine, propranolol, pindolol and atenolol. Del Giaccio, Alfredo; Eblen-Zajjur, Antonio Article InvestigacioÌ�n cliÌ�nica (2010)
Ouabain-insensitive, Na(+)-stimulated ATPase of several rat tissues=> activity during a 24 h period. Reyes, A; Galindo, M M; García, L; Segura-Pena, D; Caruso-Neves, C; Eblen-Zajjur, A; Proverbio, T; Marín, R; Proverbio, F Article Physiological research / Academia Scientiarum Bohemoslovaca (2009)
Design and implementation of an acquisition system for the photo-motor response of the iris. Lopez, C; Chumbimuni, R; Bosnjak, A; Villanueva, C; Eblen-Zajjur, A Article Conference proceedings => ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference (2007)
Influence of acute hyperglycaemia on the amplitude of nociceptive spinal evoked potentials in healthy rats. Gómez, Manuel; Bosco, Rossana; Eblen-Zajjur, Antonio Article The International journal of neuroscience (2007)
Magnesium sulphate reduces cell volume in physiological conditions but not in the cytotoxic oedema during global brain ischemia. Chacón, Andrea; Lisott, Elena; Eblen-Zajjur, Antonio Article Brain injury (2006)
Normal expression and inflammation-induced changes of Na and Na/K ATPase activity in spinal dorsal horn of the rat. Czaplinski, Mariana; Abad, Cilia; Eblen-Zajjur, Antonio Article Neuroscience letters (2005)
A blood plasma inhibitor is responsible for circadian changes in rat renal Na,K-ATPase activity. Segura, Darío; Eblen-Zajjur, Antonio; Proverbio, Fulgencio; Proverbio, Teresa; Carrera, Francisco; Caruso-Neves, Celso; Marín, Reinaldo Article The international journal of biochemistry & cell biology (2004)
Tridimensional animated brain mapping from conventional paper-ink EEG recordings. González, I; Eblen-Zajjur, A Article Computers in biology and medicine (2004)
A simple ballistocardiographic system for a medical cardiovascular physiology course. Eblen-Zajjur, Antonio Article Advances in physiology education (2003)
Inflammation induced increase of fluoride resistant acid phosphatase (FRAP) activity in the spinal dorsal horn in rats. Glykys, J; Guadama, M; Marcano, L; Ochoa, E; Eblen-Zajjur, A Article Neuroscience letters (2003)
[Radioactivity for 137Cs, 125I, 131I, 59Fe, y 57Co windows from foods included in the basic alimentary basket and in the water, consumed in the state of Carabobo, Venezuela]. Torres, Annabell; Tovar, María; Malpica, Oscar; Eblen-Zajjur, Antonio Article Acta cientiÌ�fica venezolana (2002)
[Estimation of low density lipoprotein cholesterol concentration=> regression analysis versus Friedewald's formula]. Eblen-Zajjur, A; Eblen-Zajjur, M Article Revista meÌ�dica de Chile (2001)
Cálculo de la concentración de colesterol de la lipoproteína de baja densidad: análisis de regresión versus fórmula de Friedewald Antonio Eblen Zajjur; Marta Eblen-Zajjur Article SCIELO REVISTA MEDICA DE CHILE (2001)
[Reaction time to dichotic visual stimulation and its relationship to cerebral hemispheric specialization]. Coronel, M; De Abreu, D; Eblen-Zajjur, A Article Acta cientiÌ�fica venezolana (1999)
A laboratory demonstration for learning about mast cell degranulation. Corado, J; Eblen-Zajjur, A Article The American journal of physiology (1999)
A simple analog of visual field retinal projection. Eblen-Zajjur, A Article The American journal of physiology (1997)
PAG-microinjected dipyrone (metamizol) inhibits responses of spinal dorsal horn neurons to natural noxious stimulation in rats. Vanegas, H; Tortorici, V; Eblen-Zajjur, A; Vásquez, E Article Brain research (1997)
Fractal analysis of spinal dorsal horn neuron discharges by means of sequential fractal dimension D. Eblen-Zajjur, A; Salas, R; Vanegas, H Article Computers in biology and medicine (1996)
Analysis of single and multiple neuronal discharges as point processes=> a computer program set. Eblen-Zajjur, A Article Acta cientiÌ�fica venezolana (1995)
Differential effects of spinalization on discharge patterns and discharge rates of simultaneously recorded nociceptive and non-nociceptive spinal dorsal horn neurons. Sandkühler, J; Eblen-Zajjur, A; Fu, Q G; Forster, C Article Pain (1995)
[Autoradiography of experimental blood brain barrier breakdown areas in the rat using pertechnetate as radiotracer]. Malpica, O; Eblen-Zajjur, A Article Revista de neurologia (0)
[Extrarenal effects of furosemide on normal and ischemic cerebral tissue in the rat]. Oria De Suárez, C; Eblen Zajjur, A Article Revista de neurologia (0)
Tuberculosis enfermedad reemergente: tuberculosis vulvar. Reporte de un caso Darío Saturno; Antonio Eblen-Zajjur Article InvestiGACION CLINICA


Código Neural. BookSection (2007)


Predicción de convulsiones epilépticas con modelos matemáticos BookWhole (2018)


Device for recording the vascular response of the human spinal cord triggered by a suprasensible stimulus through the use of functional near-infrared spectroscopy Sergio Uribe A.; Antonio Eblen-Zajjur; Mohit Rana; Ranganatha Sitaram Patent (2023)
Digital binocular campimetry and pupilometry for encephalic functional evaluation and neuropharmacology Guzman, Christian Dani; Antonio Eblen Zajjur Patent (2018)


Dispositivo de registro de la respuesta vascular de la médula espinal humana gatillado por un estímulo supra¬sensitivo mediante el uso de espectroscopia funcional del infrarrojo cercano. Pontificia Universidad Católica de Chile (Global-UC-2018) Proyecto 2018-2018 Coinvestigador(a)
Dispositivo de registro de la respuesta vascular de la médula espinal humana gatillado por un estímulo supra-sensitivo mediante el uso de espectroscopia funcional del infrarrojo cercano. Pontificia Universidad Católica de Chile (273132-UC) Proyecto 2017-2017 Coinvestigador(a)