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Jose Tomas Egana Erazo

Profesor asociado

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Tissue Engineering, Regenerative Medicine, Biomaterials, Human Photosynthesis, Translational Medicine.

PhD in Experimental Plastic Surgery, TECHNISCHE UNIVERSITÄT MÜNCHEN. Alemania

Profesor asistente Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

2015 - A la fecha

Founder and VP of Technology

SymbiOx Inc

Estados Unidos

2013 - A la fecha
Investigador Principal

Dept. Cirugía Plástica, Hospital Clínico de la TU München.

Alemania

2010 - 2015
Profesor Asistente Instituto de Ingeniería Biológica y Médica.

Pontificia Universidad Católica de Chile

Chile

2015 - A la fecha


Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin Castillo, Valentina; Diaz-Astudillo, Pamela; San Martin, Sebastian Article ISI SCOPUS Cells (2023)
Development of a photosynthetic hydrogel as potential wound dressing for the local delivery of oxygen and bioactive molecules Carvajal, Felipe; Miranda, Miguel; Vera, Constanza Article ISI SCOPUS Acta Biomaterialia (2023)
Photosynthetic microorganisms for the oxygenation of advanced 3D bioprinted tissues* Ortega, Javiera Sanhueza Article ISI SCOPUS Acta Biomaterialia (2023)
A Modified Burn Comb Model With a New Dorsal Frame That Allows for Local Treatment in Partial-Thickness Burns in Rats Weiss, Fabian; Agua, Kariem; Weinzierl, Andrea; Schuldt, Anna; Schlitter, Anna Melissa; Steiger, Katja; Machens, Hans-Guenther; Harder, Yves; Schmauss, Daniel Article ISI JOURNAL OF BURN CARE RESEARCH (2022)
Case report: Long-term follow-up of a large full-thickness skin defect treated with a photosynthetic scaffold for dermal regeneration Carvajal, Felipe; San Martin, Sebastian Article ISI FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2022)
Development of an implantable three-dimensional model of a functional pathogenic multispecies biofilm to study infected wounds Cardenas-Calderon, Camila; San Martin, Sebastian; Varas, Juan F. Article ISI SCIENTIFIC REPORTS (2022)
In vitro and in vivo detection of microbial gene expression in bioactivated scaffolds seeded with cyanobacteria Leibrock, L. B.; Hofmann, D. M.; Fuchs, B; Birt, A; Reinholz, M.; Guertler, A.; Frank, K.; Giunta, R. E.; Egana, J. T.; Schenck, T. L.; et al. Article ISI LETTERS IN APPLIED MICROBIOLOGY (2022)
Towards an In Vitro 3D Model for Photosynthetic Cancer Treatment: A Study of Microalgae and Tumor Cell Interactions San Martin, Sebastian Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
A First in Human Trial Implanting Microalgae Shows Safety of Photosynthetic Therapy for the Effective Treatment of Full Thickness Skin Wounds Obaid, Miguel Luis; Camacho, Juan Pablo; Brenet, Marianne; Corrales-Orovio, Rocio; Carvajal, Felipe; Martorell, Ximena; Werner, Consuelo; Simon, Valeska; Varas, Juan; Calderon, Wilfredo; et al. Article ISI FRONTIERS IN MEDICINE (2021)
Development of a Novel Perfusable Solution for ex vivo Preservation: Towards Photosynthetic Oxygenation for Organ Transplantation Veloso-Gimenez, Valentina; Necunir, David; Ehrenfeld, Carolina; Guzman, Christian Dani Article ISI FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)
Use of photosynthetic transgenic cyanobacteria to promote lymphangiogenesis in scaffolds for dermal regeneration Fuchs, Benedikt; Moellhoff, Nicholas; Hofmann, Daniel; Zhang, Lifang; Selao, Tiago Toscano; Giunta, Riccardo E.; Nickelsen, Joerg Article ISI Acta Biomaterialia (2021)
Lipoconstruct surface topography grating size influences vascularization onset in the dorsal skinfold chamber model McLuckie M.; Robotti F.; Sanchez-Macedo N.; Enderlin D.; Frese L.; Cheng P.F.; Levesque M.P.; Poulikakos D.; Lindenblatt N. Article ISI SCOPUS Acta Biomaterialia (2020)
Photosymbiosis for Biomedical Applications Article ISI FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)
Towards a biotechnological platform for the production of human pro-angiogenic growth factors in the green alga Chlamydomonas reinhardtii Article ISI SCOPUS APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2020)
A Reliable Preclinical Model to Study the Impact of Cigarette Smoke in Development and Disease Aedo, Geraldine; Miranda, Miguel Article SCOPUS Current Protocols in Toxicology (2019)
Long-term pre- and postconditioning with low doses of erythropoietin protects critically perfused musculocutaneous tissue from necrosis Schnnauss, D; Weinzierl, A; Weiss, F; Egaña, JT; Rezaeian, F; Hopfner, U; Schmauss, V; Machens, HG; Harder, Y Article ISI SCOPUS JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY (2019)
Myocardial Monophasic Action Potential Recorded by Suction Electrode for Ionic Current Studies in Zebrafish Miranda, Miguel Article ISI SCOPUS ZEBRAFISH (2019)
A Novel In Vivo Model to Study Impaired Tissue Regeneration Mediated by Cigarette Smoke Chavez, MN; Egaña, JT Article ISI SCOPUS SCIENTIFIC REPORTS (2018)
Development of photosynthetic sutures for the local delivery of oxygen and recombinant growth factors in wounds JarquÃn-Cordero M.; Hopfner, U; Holmes C.; Schmauss D.; Nickelsen J.; EgaÃ±a J.T. Article ISI SCOPUS Acta Biomaterialia (2018)
Acute stimulation of mesenchymal stem cells with cigarette smoke extract affects their migration, differentiation, and paracrine potential Wahl, Elizabeth A.; Schenck, Thilo L.; Machens, Hans-G?nther; Ega?a, J. Tom?s Article ISI SCOPUS SCIENTIFIC REPORTS (2016)
Towards autotrophic tissue engineering: Photosynthetic gene therapy for regeneration Chavez, MN; Schenck, TL; Hopfner, U; Centeno-Cerdas, C; Somlai-Schweiger, I; Schwarz, C; Machens, HG; Heikenwalder, M; Nickelsen J.; Egaña, JT Article ISI SCOPUS BIOMATERIALS (2016)
Zebrafish as an Emerging Model Organism to Study Angiogenesis in Development and Regeneration Chavez, MN; Aedo, G; Fierro, FA; Egaña, JT Article ISI SCOPUS Frontiers in Physiology (2016)
Generation of Viable Plant-Vertebrate Chimeras Alvarez, M; Reynaert, N; Chavez, MN; Aedo, G; Araya, F; Hopfner, U; Fernández, J; Egaña, JT Article ISI SCOPUS PLOS ONE (2015)
Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells Article SCOPUS Front. Cell Dev. Biol (2015)
In Vitro Evaluation of Scaffolds for the Delivery of Mesenchymal Stem Cells to Wounds Wahl, EA; Fierro, FA; Peavy, TR; Hopfner, U; Dye, JF; Machens, HG; Egaña, JT; Schenck, TL Article ISI SCOPUS BioMed Research International (2015)
Photosynthetic biomaterials: A pathway towards autotrophic tissue engineering Schenck, T. L.; Hopfner, U; Somlai-Schweiger, I; Giunta, R. E.; Nickelsen J.; Allende, ML Article ISI SCOPUS Acta Biomaterialia (2015)
A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo Schenck, T. L.; Hopfner, U; Rezaeian, F Article ISI SCOPUS JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2014)
Development of photosynthetic biomaterials for in vitro tissue engineering Hopfner, U; Schenck, TL; Chavez, MN; Machens, HG; Bohne, AV; Nickelsen J.; Giunta, RE; Egaña, JT Article ISI SCOPUS Acta Biomaterialia (2014)
Functional analysis reveals angiogenic potential of human mesenchymal stem cells from Wharton's jelly in dermal regeneration Edwards, SS; Zavala, G; Prieto, CP; Elliott, M; Martínez, S; Egaña, JT; Palma, V Article ISI SCOPUS ANGIOGENESIS (2014)
Surgical Sutures Filled with Adipose-Derived Stem Cells Promote Wound Healing Reckhenrich, AK; Kirsch, BM; Wahl, EA; Schenck, TL; Rezaeian, F; Harder, Y; Foehr, P; Machens, HG; Egaña, JT Article ISI SCOPUS PLOS ONE (2014)
Diallyl-disulphide is the effective ingredient of garlic oil that protects primary human osteoblasts from damage due to cigarette smoke Ehnert S.; Buchholz, A.; Freude T.; Schenck, T. L.; Schyschka L.; Neumaier M.; Dobele S.; Stockle U. Article ISI SCOPUS FOOD CHEMISTRY (2012)
Green tea protects human osteoblasts from cigarette smoke-induced injury: possible clinical implication Holzer N.; Ehnert S.; Schenck, T. L.; Buchholz, A.; Schyschka L.; Neumaier M.; Benzing S.; Stockle U.; Freude T. Article ISI SCOPUS Langenbeck's Archives of Surgery (2012)
N-acetylcyteine and flavonoid rich diet: The protective effect of 15 different antioxidants on cigarette smoke-damaged primary human osteoblasts Article ISI Advances in Bioscience and Biotechnology (2012)
The Use of Human Sweat Gland-Derived Stem Cells for Enhancing Vascularization during Dermal Regeneration Danner, S; Kremer, M; Nagel, S; Zhang, Z; Hopfner, U; Weber, C; Schenck, T. L.; Becker, T; Kruse, C Article ISI SCOPUS Journal of Investigative Dermatology (2012)
THE USE OF NON-VIRAL GENE VECTORS FOR BIOACTIVE POLY-(D,L-LACTIDE) IMPLANT SURFACES IN BONE TISSUE ENGINEERING Koch, C; Plank, C Article ISI SCOPUS EUROPEAN CELLS AND MATERIALS (2012)
Bioactivation of dermal scaffolds with a non-viral copolymer-protected gene vector Reckhenrich, AK; Hopfner, U; Krotz, F; Zhang, ZY; Koch, C; Kremer, M; Machens, HG; Plank, C; Egaña, JT Article ISI BIOMATERIALS (2011)
Enhanced Collateral Growth by Double Transplantation of Gene-Nucleofected Fibroblasts in Ischemic Hindlimb of Rats Zhang, ZY; Slobodianski A.; Ito, WD; Arnold, A.; Nehlsen J.; Weng, SX; Lund, N; Liu, JH; Egaña, JT; Lohmeyer, JA; et al. Article ISI SCOPUS PLOS ONE (2011)
Quercetin Protects Primary Human Osteoblasts Exposed to Cigarette Smoke through Activation of the Antioxidative Enzymes HO-1 and SOD-1 Braun, KF; Ehnert S.; Freude T.; Egaña, JT; Schenck, TL; Buchholz, A.; Schmitt, A; Siebenlist S.; Schyschka L.; Neumaier M.; et al. Article ISI SCOPUS The Scientific World Journal (2011)
The role of single cell derived vascular resident endothelial progenitor cells in the enhancement of vascularization in scaffold-based skin regeneration Zhang, ZY; Ito, WD; Hopfner, U; Bohmert B.; Kremer, M; Reckhenrich, AK; Harder, Y; Lund, N; Kruse, C; Machens, HG; et al. Article ISI SCOPUS Biomaterials (2011)
Ex vivo method to visualize and quantify vascular networks in native and tissue engineered skin Egaña, JT; Condurache, A; Lohmeyer, J; Kremer, M; Stockelhuber, B; Lavandero, S; Machens, HG Article ISI SCOPUS LANGENBECKS ARCHIVES OF SURGERY (2009)
The use of glandular-derived stem cells to improve vascularization in scaffold-mediated dermal regeneration Egaña, JT; Danner, S; Kremer, M; Rapoport, DH; Lohmeyer, JA; Dye, JF; Hopfner, U; Lavandero, S; Kruse, C; Machens, HG Article ISI SCOPUS BIOMATERIALS (2009)
Use of Human Mesenchymal Cells to Improve Vascularization in a Mouse Model for Scaffold-Based Dermal Regeneration Egaña, JT; Fierro, FA; Kruger, S; Bornhauser, M; Huss, R; Lavandero, S; Machens, HG Article ISI SCOPUS TISSUE ENGINEERING PART A (2009)
Oxidative stress promotes T dephosphorylation in neuronal cells: The roles of cdk5 and pp1 Zambrano, CA; Egaña, JT; Maccioni, RB; González-Billault, C Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2004)
Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures Egaña, JT; Zambrano, C.; González-Billault, C; Maccioni, RB Article ISI BIOMETALS (2003)


Towards Autotrophic Tissue Engineering: Photosynthetic Biomaterials for Tissue Regeneration Rosas, MNC; Schenck, TL; Hopfner, U; Centeno, C; Machens, HG; Somlai-Schweiger, I; Heikenwalder, M; Schwarz, C; Nickelsen J.; Egaña, JT Abstract ISI TISSUE ENGINEERING PART A (2015)
Use of pancreas-derived stem cells to improve vascularization in skin tissue engineering Egaña, JT; Danner, S; Kremer, M; Rapoport, DH; Lavandero, S; Kruse, C; Machens, HG Abstract ISI TISSUE ENGINEERING PART A (2008)