Microbiology and Immunology - Cellular Biology - Innate Immunity - Host-pathogen interactions

Teaching experience at Pontificia Universidad Católica de Valparaíso:

Undergraduate Courses
BIO 122 Cell Biology for the Biochemical Engineering program
BIO 1224 Research Unit 1 for the Bachelor's degree in Biology program
BIO 208 Immunology for the Biology and Natural Sciences program
BIO 505 Immunology for the Biochemistry program
BIO 1133 Molecular Biology for the Bachelor of Science program
BIO 336 Cellular Physiology for the Biochemistry program
BIO 131 Cell Biology for the Kinesiology program
BIO 328 Cell Biology for the Medical Technology program
BIO 1113 Cellular and Molecular Biology for the Medical Technology program

Graduate Courses
Participation in courses taught at the Master's Program in Microbiological Sciences, Institute of Biology:
BIO 700 Molecular Bases of Immune Response in Marine Invertebrates
BIO 760 Advanced Microbiological Sciences
BIO 761 Methods in Microbiological Sciences
BIO 703 Immunology in Pathogen-Host Interaction
BIO 1005 Antimicrobial Peptides

Participation in courses taught at the Doctorate Program in Aquaculture, cooperative program UCh/UCN/PUCV:
DAC 903 Molecular Biology of Pathogens and Immunity in Aquaculture
DAC 932 Computational Tools for Molecular Biology

Supervision of thesis and seminars:

Graduate:
1. March 2025: Effect of Biofloc Technology Farming on the Intestinal Bacterial Microbiota Composition and Immune Gene Expression in the Freshwater Shrimp Cryphiops caementarius.” Student: Elisa Torres Lagos. Doctorate in Biology and Applied Ecology, UCN (co-supervision).
2. January 2025: "Characterization of the antibacterial and immunomodulatory activity of antimicrobial effectors from the scallop Argopecten purpuratus and the effect of their administration on the survival of larvae exposed to the pathogen Vibrio bivalvicida." Student: Jormil Revilla. Doctorate in Aquaculture, cooperative program UCh/UCN/PUCV (co-supervision).
3. 2024: “Reasignación energética en ostiones juveniles frente a estresores múltiples asociados a surgencia: balance entre crecimiento y respuesta estrés-inmune”. Student: Antonia Jorquera. Master in Microbiological Sciences. Pontifical Catholic University of Valparaíso
4. 2024: “Caracterización de determinantes de virulencia de la bacteria patógena de ostiones Vibrio bivalvicida”. Student: Max Santelices. Master in Microbiological Sciences. Pontifical Catholic University of Valparaíso
5. 2024: "Characterization of probiotic bacterial strains associated with larvae of the scallop Argopecten purpuratus with a phenotype resistant to Vibrio bivalvicida." Student: Katherine Muñoz. Doctorate in Biotechnology, cooperative program PUCV/UTFSM.
6. 2023. “Expresión de genes inmunes en larvas del ostión Argopecten purpuratus como biomarcadores de susceptibilidad al patógeno Vibrio bivalvicida VPAP30”. Student: Eduardo Jeria. Master in Microbiological Sciences. Pontifical Catholic University of Valparaíso
7. 2020-present: "Characterization of bioactive peptides with antimicrobial activity derived from microalgae with potential for aquaculture." Student: Pabla Ugalde. Doctorate in Aquaculture, cooperative program UCh/UCN/PUCV (co-supervision).
8. 2022: "Analysis of the de novo transcriptome of hemocytes from the scallop Argopecten purpuratus and identification of novel antimicrobial peptides." Student: Felipe Stambuk. Master's in Microbiological Sciences. Pontifical Catholic University of Valparaíso.
9. 2022: "Identification of genes associated with the immune response throughout larval and post-larval development of the scallop Argopecten purpuratus and the effect of a diet rich in polyunsaturated fatty acids on their expression in response to the pathogenic bacterium Vibrio splendidus." Student: Isis Rojas. Doctorate in Aquaculture, cooperative program UCh/UCN/PUCV (co-supervision).
10. 2021: "Immune response effectors and their impact on the composition of bacterial microbiota in Argopecten purpuratus." Student: Roxana González. Doctorate in Aquaculture, cooperative program UCh/UCN/PUCV.
11. 2017: "Detection of pathogens responsible for infectious ocular keratitis in humans using multiple qPCR with fluorescent probes." Student: Helen Gutiérrez. Master's in Microbiological Sciences. Pontifical Catholic University of Valparaíso (co-supervision).
12. 2016: "Respiratory burst and its modulatory function on the expression of antimicrobial effectors in hemocytes of Argopecten purpuratus induced by pathogen-associated molecular patterns." Student: Daniel Oyanedel. Master's in Microbiological Sciences. Pontifical Catholic University of Valparaíso.
13. 2016: "Evaluation of the biological activity of synthetic peptides obtained from the microalgae Tetraselmis suecica." Student: Genezareth Wong. Master's in Microbiological Sciences. Pontifical Catholic University of Valparaíso (co-supervision).

Undergraduate:
1. 2022-2023: "Lipopolysaccharide-binding protein (LBP) as a biomarker of resistance to the pathogen Vibrio bivalvicida in larvae of the Pacific scallop Argopecten purpuratus." Student: Camila Montesinos. Biochemistry program. Pontifical Catholic University of Valparaíso.
2. 2022-2023: "Potential genetic manipulation of Vibrio bacteria." Student: Ambar Perez. Biochemistry program. Pontifical Catholic University of Valparaíso.
3. 2021: "Production and purification of the bactericidal protein with increased bacterial permeability ApLBP/BPI1 from the Pacific scallop Argopecten purpuratus in Pichia pastoris." Student: Camila Muñoz. Biochemistry program. Pontifical Catholic University of Valparaíso.
4. 2020: "Functional characterization of the C-type lectin receptor (ApCLR) expressed in hemocytes of the scallop Argopecten purpuratus." Student: Valentina Muñoz. Biochemistry program. Pontifical Catholic University of Valparaíso.
5. 2020: "Cloning and molecular characterization of two isoforms of interleukin-17 from the scallop Argopecten purpuratus." Student: Yurubi Borregales. Biochemistry program. Pontifical Catholic University of Valparaíso.
6. 2018-2019: "Establishment of molecular surface markers on hemocytes of the scallop Argopecten purpuratus: Toll-like receptors and Mannose receptors." Student: Varinia Morales. Marine Biology program. University of Valparaíso.
7. 2016-2017: "Immunity-microbiota interaction in the scallop Argopecten purpuratus: identification of immune response biomarkers." Student: Katherine Muñoz. Biochemistry program. Pontifical Catholic University of Valparaíso.
8. 2016-2017: "Identification and molecular characterization of a lysozyme G in the scallop Argopecten purpuratus (Lamark, 1819) and its potential role as an immune response biomarker." Student: Daniel González. Marine Biology program. University of Valparaíso.
9. 2015: "Standardization of a primary culture method for hemocytes of the Northern scallop Argopecten purpuratus for in vitro immune response evaluation." Student: Bárbara González. Biology Pedagogy program. Pontifical Catholic University of Valparaíso.
10. 2015: "Expression and purification of recombinant Interleukin-1? protein from rainbow trout Oncorhynchus mykiss produced in Escherichia coli." Student: Roberto Cisternas. Biology Pedagogy program. Pontifical Catholic University of Valparaíso.