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Felipe Ignacio Scott Contador

Associate Professor

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

Experimental, modeling, simulation and optimization of biochemical systems and biorefineries Methods development and applications in System Biology. Gas biofiltration of VOCs and PAHs Polyhydroxyalkanoates and hydroxy acids production.

Biochemical Engineering, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2015
Ingeniería Civil Bioquímica, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2009
Biochemical Engineer, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2010

Assistant Professor Full Time

Universidad de los Andes

Faculty of Engineering and Applied Sciences

Santiago, Chile

2015 - 2021

Assistant professor Full Time

Universidad de los Andes

Chile

2015 - 2021
R&D Engineer Part Time

Consorcio Tecnológico Bioenercel S.A

Chile

2010 - 2014
Doctoral researcher Full Time

Pontificia Universidad Católica de Valparaíso

Chile

2010 - 2015
Associate Professor Full Time

Universidad de los Andes

Santiago, Chile

2021 - A la fecha

The following undergraduate and graduate works have been guided or are under development.

Thesis
1. Francisco España. 2022-2025. A framework for the design of eco-industrial parks for carbon capture and utilization. Universidad de los Andes (Ph.D.)
2. Luz Yañez. 2018-2022. Study of alternative metabolic pathways for the production of (R)-3-hydroxybutyric acid in polyhydroxybutyrate producing bacteria. Universidad de los Andes (Ph.D.)
3. Paz Torres. 2022-2024. Genome scale metabolic model of the knallgas bacterium Rhodococcus opacus DSM 43205. Master in Engineering sciences thesis.
4. Ignacia Molina. 2022-2024. Isopropanol production in Ralstonia eutropha and Azohydromonas lata. Master in Engineering sciences thesis.
5. Pablo Rolle. 2021-2023. Deleción de los genes de acumulación de PHB y reducción de 3-hidroxibutirato en Ralstonia eutropha y Azohydromonas lata y modelación de los efectos sobre el metabolismo. Tesis de Magister, Universidad de los Andes.
6. Javier Saavedra. 2021-2023. Modificación genética del ciclo de PHB en Ralstonia eutropha h16 para el aumento en la producción de (R)-3-hidroxybutirato. Tesis de Magister, Universidad de los Andes.

Final engineering works
1. Juan Iturralde 2022-2023. Desarrollo de un turbidostato controlado por un sensor de densidad optica de bajo costo, para el crecimiento y evolucion de metilótrofos. Memoria de pregrado. Universidad de los Andes.
2. Natalia Fernández 2022-2023. Desarrollo y demostración del uso de un ?sistema de control de alimentación de metanol para cultivos metilotroficos en biorreactor. Memoria de pregrado. Universidad de los Andes.
3. Bruno Trujillo. 2021-2022. Evaluación de sustratos diferentes a la glucosa o sacarosa en la producción de coenzima Q10 en Rhodobacter sphaeroides. Memoria de pregrado. Universidad de los Andes.
4. Paz Torres. 2021-2022. Construcción de un modelo a escala reducido del metabolismo central del carbono en Rhodococcus opacus DSM 43205. Memoria de pregrado,
5. Belen Espinoza. 2020. Development of a metabolic model calibration method using an interior point relaxation. Universidad de los Andes (undergraduate level).
6. Benjamín Robert. 2020. A repeated fed-batch strategy for the production of R-3-hydroxybutyrate using Azohydromonas lata. Universidad de los Andes (undergraduate level).
7. Francisca Pérez. 2020. Techno-economic evaluation of short-chain esters production in Ralstonia eutropha using autotrophic and heterotrophic cultures. Universidad de los Andes (undergraduate level).
8. Sofia Iglesias. 2020.Techno-economic evaluation of a repeated fed-batch strategy for the production of R-3-hydroxybutyrate and its comparison with a fed-batch process. Universidad de los Andes (undergraduate level).
9. Angela Fernández. 2018. Assessment of the PHB depolymerization capabilities of Azohydromonas lata. Universidad San Sebastian (undergraduate level).
10. Camilo Diaz. 2018. Degradation of odorous compounds from a rendering plant by Fusarium solani and Rhodococcus erythropolis. Universidad de Chile (undergraduate level).
11. Gianfranco Di Carlo. 2017. Techno-economic analysis of purification scale-up of modified salmon proteins. Universidad de los Andes (undergraduate level).
12. Vicente Soto Armijo. 2017. Numerical implementation and benchmarking of a new, gradient-flow based, non-linear optimization method. Universidad de los Andes (undergraduate level).
13. Lucas David. 2017. Techno-economic analysis and Life Cycle Assessment of 3-hydroxy-butyric acid from biomass. Universidad de los Andes (undergraduate level).
14. Felipe Moreira. 2017. Formic acid from captured CO2 and solar energy: a techno-economic and risk assessment. Universidad de los Andes (undergraduate level).
15. Diego Labbé Alessandrini. 2017. Product diversification for increasing profitability of biomass power plants. Universidad de los Andes (undergraduate level).
16. Juan Valín Acuña. 2016. Techno-economic analysis of liquid fuel production from renewable solar hydrogen. Universidad de los Andes (undergraduate level).
17. Martín Arrivillaga Guzmán. 2016. An economic comparison of alternative industrial uses of wood in Chile. Universidad de los Andes (undergraduate level).

Capacitación en Transferencia Tecnológica

CORPORACION DE FOMENTO DE LA PRODUCCION

Chile, 2014

Financiamiento a través del programa CORFO de Capacitación en Transferencia Tecnológica para participar en el curso Technology Transfer Training Program 2015 at IC2 Institute en Austin, Texas.
Beca de pasantía doctoral en el extranjero

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2012

2012 Beca de pasantía doctoral en el extranjero (Instituto de Ingeniería Química, Universidad de Alicante. España). Otorgada por el programa Becas Chile.
Apoyo tesis doctoral en Chile

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2011

Beca de apoyo al desarrollo de tesis doctorales en Chile. Otorgada por la Comisión Nacional de Ciencia y Tecnología (CONICYT).
Beca Estudios Doctorales

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2010

2010 Beca para estudios de doctorado en Chile. Otorgada por la Comisión Nacional de Ciencia y Tecnología (CONICYT).
Premio Roberto Ovalle Aguirre

INSTITUTO DE INGENIEROS DE CHILE

Chile, 2011

2010 Premio Roberto Ovalle Aguirre, concedido por el Instituto de Ingenieros de Chile en reconocimiento al mejor proyecto de titulación relacionado con la instalación o explotación de una industria relevante para el fomento de la economía nacional.


A radial-flow device for the biopurification of a model VOC- and wood-smoke- contaminated confined space San Martin-Davison, Jessica; Scott, Felipe; Vergara-Ojeda, Christian; Moreno-Casas, Patricio; Hort, Cecile; Vergara-Fernandez, Alberto Article ISI JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY (2024)
A convenient method to validate the gas flow of a CFD-CT simulation applied on a packed bed used in gas biofiltration through residence time distributions Carreno-Lopez, Felipe; Moreno-Casas, Patricio A.; Scott, Felipe; Iza, Jon; Sierra-Pallares, Jose; Munoz, Raul; Vergara-Fernandez, Alberto Article ISI CHEMICAL ENGINEERING JOURNAL (2023)
Production of poly (3-hydroxybutyrate) and extracellular polymeric substances from glycerol by the acidophile Acidiphilium cryptum Gonzalez, Ernesto; Zuleta, Camila; Zamora, Guiselle; Maturana, Nataly; Ponce, Belen; Rivero, Maria Virginia; Rodriguez, Alberto; Soto, Juan Pablo; Scott, Felipe; Diaz-Barrera, Alvaro Article ISI EXTREMOPHILES (2023)
Life Cycle Assessment of Bioethanol Production: A Case Study from Poplar Biomass Growth in the US Pacific Northwest Morales-Vera, Rodrigo; Vasquez-Ibarra, Leonardo; Scott, Felipe; Puettmann, Maureen; Gustafson, Richard Article ISI FERMENTATION-BASEL (2022)
Production of (R)-3-hydroxybutyric acid from methane by in vivo depolymerization of polyhydroxybutyrate in Methylocystis parvus OBBP Yanez, Luz; Rodriguez, Yadira; Scott, Felipe; Vergara-Fernandez, Alberto; Munoz, Raul Article ISI BIORESOURCE TECHNOLOGY (2022)
Antarctic Rahnella inusitata: A Producer of Cold-Stable beta-Galactosidase Enzymes Nunez-Montero, Kattia; Salazar, Rodrigo; Santos, Andres; Gomez-Espinoza, Olman; Farah, Scandar; Troncoso, Claudia; Hoffmann, Catalina; Melivilu, Damaris; Scott, Felipe; Barrientos Diaz, Leticia Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Antarctic Rahnella inusitata: A Producer of Cold-Stable β-Galactosidase Enzymes Nunez-Montero, Kattia; Salazar, Rodrigo; Santos, Andres; Gómez-Espinoza, Olmán; Farah, Scandar; Troncoso, Gabriela; Hoffman, Catalina; Melivilu, Damaris; Scott, Felipe; Barrientos Díaz, Leticia Article INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Biodegradation of 2,5-dimethylpyrazine in gas and liquid phase by the fungus Fusarium solani Araya, Blanca; Diaz, Camilo; San Martin, Jessica; Vergara-Fernandez, Alberto; Aroca, German; Scott, Felipe Article ISI JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY (2021)
Characterization of the microbial community in a biotrickling filter treating a complex mixture of gaseous compounds causing odor nuisance Aguirre, Alberto; Gentina, Juan C.; Malhautier, Luc; Fanlo, Jean-Louis; Vergara-Fernandez, Alberto; Scott, Felipe; Aroca, German Article ISI JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY (2021)
Two internal bottlenecks cause the overflow metabolism leading to poly (3-hydroxybutyrate) production in Azohydromonas lata DSM1123 Scott, Felipe; Yanez, Luz; Conejeros, Raul; Araya, Blanca; Vergara-Fernandez, Alberto Article ISI JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2021)
A comparative assessment of the performance of fungal-bacterial and fungal biofilters for methane abatement Vergara-Fernandez, Alberto; Scott, Felipe; Carreno-Lopez, Felipe; Aroca, German; Moreno-Casas, Patricio; Gonzalez-Sanchez, Armando; Munoz, Raul Article ISI JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2020)
Beyond Intracellular Accumulation of Polyhydroxyalkanoates: Chiral Hydroxyalkanoic Acids and Polymer Secretion Yanez, Luz; Conejeros, Raul; Vergara-Fernandez, Alberto; Scott, Felipe Article ISI FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)
Computational tomography and CFD simulation of a biofilter treating a toluene, formaldehyde and benzo[α]pyrene vapor mixture Moreno-Casas, Patricio A.; Scott, Felipe; Delpiano, José; Vergara-Fernández, Alberto Article ISI SCOPUS CHEMOSPHERE (2020)
Mechanistic Description of Convective Gas–Liquid Mass Transfer in Biotrickling Filters Using CFD Modeling Moreno-Casas, Patricio A.; Scott, Felipe; Delpiano, José; Abell, José A.; Caicedo, Francisco; Muñoz, Raúl; Vergara-Fernández, Alberto Article SCOPUS ENVIRONMENTAL SCIENCE AND TECHNOLOGY (2019)
Methane biodegradation and enhanced methane solubilization by the filamentous fungi Fusarium solani. Vergara-FernÃ¡ndez A.; Morales P.; Scott F.; Guerrero S.; YaÃ±ez L.; Mau S.; Aroca G. Article ISI SCOPUS CHEMOSPHERE (2019)
Simultaneous use of CO and naphthalene for the reduction of NO on potassium promoted copper catalyst supported on Ce/TiO2-SiO2 and in the presence of oxygen Morales, C; Lopez, N; Aguila, G; Araya, P; Scott, F; Vergara-Fernandez, A; Guerrero, S Article ISI SCOPUS MATERIALS CHEMISTRY AND PHYSICS (2019)
Biofiltration of benzo[alpha] pyrene, toluene and formaldehyde in air by a consortium of Rhodococcus erythropolis and Fusarium solani: Effect of inlet loads, gas flow and temperature Vergara-Fernández, Alberto; Yánez, Diana; Morales, Paulina; Scott, Felipe; Aroca, Germán; Diaz-Robles, Luis; Moreno-Casas, Patricio Article ISI SCOPUS CHEMICAL ENGINEERING JOURNAL (2018)
Biofiltration of volatile organic compounds using fungi and its conceptual and mathematical modeling Vergara-Fernandez, Alberto; Revah, Sergio; Moreno-Casas, Patricio; Scott, Felipe Article ISI SCOPUS BIOTECHNOLOGY ADVANCES (2018)
Simulation and optimization of dynamic flux balance analysis models using an interior point method reformulation Scott F.; Wilson P.; Conejeros R.; Vassiliadis V.S. Article ISI SCOPUS Computers and Chemical Engineering (2018)
A generalized disjunctive programming framework for the optimal synthesis and analysis of processes for ethanol production from corn stover Scott, Felipe; Aroca, Germán; Caballero, José Antonio; Conejeros, Raúl Article ISI SCOPUS BIORESOURCE TECHNOLOGY (2017)
Biodegradation of benzo[alpha]pyrene, toluene, and formaldehyde from the gas phase by a consortium of Rhodococcus erythropolis and Fusarium solani Morales, Paulina; Cáceres, Manuel; Scott, Felipe; Diaz-Robles, Luis; Aroca, Germán; Vergara-Fernández, Alberto Article ISI SCOPUS APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)
Constrained NLP via gradient flow penalty continuation: Towards self-tuning robust penalty schemes Scott, Felipe; Conejeros, Raúl; Vassiliadis, Vassilios Article ISI SCOPUS COMPUTERS & CHEMICAL ENGINEERING (2017)
On the solution of differential-algebraic equations through gradient flow embedding del Rio-Chanona, Antonio; Bakker, Craig; Fiorelli, Fabio; Paraskevopoulos, Michail; Scott, Felipe; Conejeros, Raúl; Vassiliadis, Vassilios Article ISI SCOPUS COMPUTERS & CHEMICAL ENGINEERING (2017)
Elucidating the key role of the fungal mycelium on the biodegradation of n-pentane as a model hydrophobic VOC Vergara-Fernández A.; Scott, F.; Moreno-Casas, P.; Díaz-Robles L.; Munoz, R. Article ISI SCOPUS CHEMOSPHERE (2016)
Corn stover semi-mechanistic enzymatic hydrolysis model with tight parameter confidence intervals for model-based process design and optimization Scott, F.; Li, M; Williams D.L.; Conejeros R.; Hodge D.B.; Aroca G. Article ISI SCOPUS BIORESOURCE TECHNOLOGY (2015)
Attainable region analysis for continuous production of second generation bioethanol Scott, F.; Conejeros R.; Aroca G. Article ISI SCOPUS Biotechnology for Biofuels (2013)
Selection of process alternatives for lignocellulosic bioethanol production using a MILP approach Scott, F.; Venturini, F; Aroca G.; Conejeros R. Article ISI SCOPUS BIORESOURCE TECHNOLOGY (2013)


Removal of Gaseous Pollutants from Air by Fungi Moreno-Casas, Patricio; Revah, Sergio; Vergara-Fernández, Alberto; Scott, Felipe BookSection (2019)
Technical and economic analysis of industrial production of lactose-derived prebiotics Scott, Felipe; Vera, Carlos; Conejeros, Raúl BookSection (2016)


Decreasing specific volumetric energy consumption for gas mass transfer through different bioreactor configurations: a study of CO2 conversion to value-added products at high gas conversion Alberto Vergara-Fernández Proyecto (2024)
Fueling a new sustainable industry in Chile via integrated and intensified bio-electro-chemical processes for CO2 upcycling using green hydrogen and renewable energy for alleviating climate change Alberto Vergara-Fernández; Scott, Felipe; GUERRERO, SICHEM; Aroca, German; Conejeros, Raul Jorge; Gonzalez, Ernesto; Ottone, Carminna Proyecto (2022)
Sistema Integrado de Alta Eficiencia para la captura y destrucción de contaminantes de aire de interior (UnitAir). Felipe Scott; Alberto Vergara-Fernández; GUERRERO, SICHEM Proyecto (2022)
ENGINEERING AZOHYDROMONAS LATA AND RALSTONIA EUTROPHA FOR THE PRODUCTION OF HYDROXY ACIDS. Felipe Scott; Aroca, German; Conejeros, Raul; Vergara-Fernandez, Alberto; Felipe Arenas Proyecto (2021)
Engineering a microbial community for the biofiltration of phenanthrene vapor biodegradation Alberto Vergara-Fernández; Felipe Scott Proyecto (2019)
Biopurificación de Aire de Interiores: mejora de la salud, bienestar y productividad. Escala Piloto. ETAPA 2 Alberto Vergara-Fernández; Felipe Scott; Germán Aroca; Patricio Moreno-Casas; Sichem Guerrero Proyecto (2018)
INCREASING (R)-3-HYDROXYBUTYRIC ACID YIELD AND PRODUCTIVITY USING A REPEATED FED-BATCH STRATEGY WITH CELL RECYCLE Felipe Scott Proyecto (2018)
Treatment of industrial gaseous emissions causing odor nuisance using a series of biotrickling filters German Aroca; Felipe Scott Proyecto (2018)
Dispositivo catalítico autónomo y de bajo costo basado en cobre para la eliminación de contaminantes en calefactores a leña FONDEF (FONDEF-IDe) Proyecto 2017-2019 Investigador(a)
Escalamiento de la purificación de proteínas funcionalizadas de gelatina Universidad de los Andes (PMI UAN 1301 – 403) Proyecto 2017-2018 Director(a)
Caracterización de la actividad de enzimas activas en frío=> desde la Antártica a la industria láctea, industria de biocombustibles, alimentos y detergentes. Universidad de los Andes-Universidad de la Frontera (UAN1301-403) Proyecto 2016-2017 Subdirector(a)
Fortalecimiento de las capacidades de transferencia tecnológica y comercialización de innovaciones tecnológicas asociadas al sector de la bioenergía y los bioproductos mediante la capacitación en el centro IC2 de la University of Texas at Austin CORFO (14CHTT-33973) Proyecto 2015-2015 Director(a)
Desarrollo de una estrategia de producción de alcoholes de cadena media para la fabricación de combustible de aviación INNOVA CORFO (12IDL1-16033.) Proyecto 2013-2013 Investigador(a)
Biochemical reaction pathway analysis subject to system trajectory validation under box parametric uncertainty FONDECYT (1080118) Proyecto 2009-2011 Tesista
Consorcio Tecnológico Bioenercel S.A. CORFO, CMPC, Arauco, MASISA, Fundación Chile, Universidad de Concepción, Pontificia Universidad Católica de Valparaíso (INNOVA CORFO, 208-7320) Proyecto 2009-2014 Investigador(a)


Process design and sustainability in the production of bioethanol from lignocellulosic materials Scott, Felipe; Quintero, Julián; Morales, Marjorie; Conejeros, Raúl; Cardona, Carlos; Aroca, German Review ISI SCOPUS ELECTRONIC JOURNAL OF BIOTECHNOLOGY (2013)