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Ian Burbulis

Academic Professor Regular

Universidad San Sebastian

Puerto Montt, Chile

Estoy investigando cómo el mosaicismo somático afecta la vida humana saludable. Desarrollo herramientas multiómicas para medir eventos moleculares en células individuales. Usamos este conocimiento para comprender y tratar enfermedades de la vejez.

Biologia y Química, VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY. Estados Unidos, 1995
Biología molecular y genética, VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY. Estados Unidos, 1998

Assistant Professor: Department of Biochemistry and Molecular Genetics Part Time

UNIVERSITY OF VIRGINIA

Medicine

Charlottesville, VA, Estados Unidos

2013 - A la fecha
Profesor y Investigador: Departamento de medicina Full Time

UNIVERSIDAD SAN SEBASTIAN

Puerto Montt, Chile

2016 - A la fecha

Becaria de investigación

Molecular Sciences Institute: NHGRI centro de excelencia en Ciencias Genómicas

Estados Unidos

2002 - 2004
Instructor de programa: Programa de pasantías de minorías insuficientemente representadas

Molecular Sciences Institute: NHGRI centro de excelencia en Ciencias Genómicas

Estados Unidos

2003 - 2004
Investigador Senior

Molecular Sciences Institute

Estados Unidos

2004 - 2009
Radiación y oficial de seguridad de producto químico

Molecular Sciences Institute

Estados Unidos

2004 - 2012
Instructor de programa: Programa de pasantías de minorías insuficientemente representadas

Molecular Sciences Institute: NHGRI centro de excelencia en Ciencias Genómicas

Estados Unidos

2006 - 2007
Asesor científico

Amino Arrays, Inc.

Estados Unidos

2006 - 2010
Miembro fundador: Miembro del Comité Ejecutivo

Green Pacific Biologicals, Inc.

Estados Unidos

2007 - 2016
Investigador completo

Molecular Sciences Institute

Estados Unidos

2009 - 2011
Miembro fundador: Investigador completo

VTT/MSI Molecular Sciences Institute

Estados Unidos

2011 - 2012
Referee

Journal of Molecular Biology

Estados Unidos

2003 - A la fecha
Referee

Journal of Clinical Chemistry

Estados Unidos

2004 - A la fecha
Review Panelist: SBIR/STTR Bioprocessing Enhancement

National Science Foundation

Estados Unidos

2007 - 2007
Review Panelist: Innovative Molecular Analysis Technologies

National Cancer Institute

Estados Unidos

2009 - 2010
Editorial Board Member: Organic Chemistry

Biological and Chemical Publishing

China

2014 - A la fecha
Co-Instructor: Single-Cell Analysis Course

Cold Spring Harbor Labs

Estados Unidos

2015 - 2016

McDonnell Fellowship

Salk Institute

Estados Unidos, 2015

Fellowship to sequence the genome and transcriptome of single neurons.
McDonnell Fellowship

Salk Institute

Estados Unidos, 2016

Develop method to sequence the genome and transcriptome of single neurons.
Gordon Conference travel award

VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY BLACKSBURG

Estados Unidos, 1999

Funding to support travel and participation in the Gordon Conference Series
Best Student Paper / Presentation

VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY BLACKSBURG

Estados Unidos, 1997

75th Annual Meeting of the Virginia Academy of Sciences.
Sigma Xi Grants-in-Aid-of-Research Funding

VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY BLACKSBURG

Estados Unidos, 1997

Thermodynamic analysis of the flavonoid enzyme complex.
Graduate Research Development Program Funding

VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY BLACKSBURG

Estados Unidos, 1996

Thermodynamic analysis of flavonoid enzyme complex assembly.
Graduate Travel Award to host Paul Srere, Ph.D.

VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY BLACKSBURG

Estados Unidos, 1995

Administration of Graduate seminar series.
Phi Beta Kappa

VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY BLACKSBURG

Estados Unidos, 1993

Mu Chapter. Virginia Tech. Blacksburg, VA.
Sigma Xi Grants in Aid of Research Funding

VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY BLACKSBURG

Estados Unidos, 1994

Analysis of multi-enzyme catalytic domains involved with substrate product channeling.
Fairfax County Medical Society Scholarship

FairFax County Medical Society

Estados Unidos, 1993

Competitive Scholarship funding to attend university.
Distinguished University Academic Honors

VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY BLACKSBURG

Estados Unidos, 1993

Highest Academic Honors available to undergraduates.


Isolation of a New Infectious Pancreatic Necrosis Virus (IPNV) Variant from Genetically Resistant Farmed Atlantic Salmon (Salmo salar) during 2021-2022 Godoy, Marcos; Kibenge, Molly J. T.; de Oca, Marco Montes; Pontigo, Juan Pablo; Coca, Yoandy; Caro, Diego; Kusch, Karina; Suarez, Rudy; Burbulis, Ian; Kibenge, Frederick S. B. Article ISI PATHOGENS (2022)
Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis Michel, Nadine; Young, Heather M. Raimer; Atkin, Naomi D.; Arshad, Umar; Al-Humadi, Reem; Singh, Sandeep; Manukyan, Arkadi; Gore, Lana; Burbulis, Ian E.; Wang, Yuh-Hwa; McConnell, Michael J. Article ISI SCIENTIFIC REPORTS (2022)
New Quinone Antibiotics against Methicillin-Resistant S. aureus Campanini-Salinas, Javier; Andrades-Lagos, Juan; Hinojosa, Nicolas; Moreno, Fabian; Alarcon, Pedro; Gonzalez-Rocha, Gerardo; Burbulis, Ian E.; Vasquez-Velasquez, David Article ISI ANTIBIOTICS-BASEL (2021)
Single-cell sequencing of the small and AT-skewed genome of malaria parasites Liu, Shiwei; Huckaby, Adam C.; Brown, Audrey C.; Moore, Christopher C.; Burbulis, Ian; McConnell, Michael J.; Guler, Jennifer L. Article ISI GENOME MEDICINE (2021)
Nanobody LAMPoles: Novel tools for dengue virus and Zika virus diagnosis Grab, D.J.; Sharma, A.; Burbulis, I.E.; Lehrer, A.T.; Nerurkar, V.; Magez, S. Article JOURNAL OF IMMUNOLOGY (2020)
Cytosolic phosphoenolpyruvate carboxykinase is expressed in α‐cells from human and murine pancreas Westermeier, Francisco; Holyoak, Todd; Gatica, Rodrigo; Martínez, Fernando; Negrón, Marianne; Yáñez, Alejandro J.; Nahmias, Daniel; Nualart, Francisco; Burbulis, Ian; Bertinat, Romina Article JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Gluconeogenic Enzymes in beta-Cells: Pharmacological Targets for Improving Insulin Secretion Westermeier F., Holyoak T., Asenjo J., Gatica R., Nualart F., Burbulis I., Bertinat R. Article ISI SCOPUS TRENDS IN ENDOCRINOLOGY AND METABOLISM (2019)
Neurons with Complex Karyotypes Are Rare in Aged Human Neocortex Chronister, WD; Burbulis, IE; Wierman, MB; Wolpert, MJ; Haakenson, MF; Smith, ACB; Kleinman, JE; Hyde, TM; Weinberger, DR; Bekiranov, S; McConnell, MJ Article ISI SCOPUS CELL REPORTS (2019)
Improved molecular karyotyping in glioblastoma Burbulis, Ian E.; Wierman, Margaret B.; Wolpert, Matt; Haakenson, Mark; Lopes, Maria-Beatriz; Schiff, David; Hicks, James; Loe, Justin; Ratan, Aakrosh; McConnell, Michael J. Article ISI SCOPUS MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2018)
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network Brain Somatic Mosaicism Network; Sherman, Maxwell A.; McConnell, Michael J.; Shin, Joo Heon; Abyzov, Alexej; Song, Saera; Bae, Taejeong; Straub, Richard E.; Erwin, Jennifer A.; Thorpe, Jeremy; Flasch, Diane A.; Weinberger, Daniel R.; Ganz, Javier; Urban, Alexander E.; Kwan, Kenneth Y.; Zhou, Bo; Lodato, Michael A.; Gage, Fred H.; Paquola, Apua C. M.; Lehner, Thomas; Rosenbluh, Chaggai; Senthil, Geetha; Moran, John V.; Walsh, Christopher A.; Cortes-Ciriano, Isidro; Chess, Andrew; Freed, Donald; Courchesne, Eric; Kwon, Minseok; Gleeson, Joseph G.; Rodin, Rachel E.; Kidd, Jeffrey M.; Akbarian, Schahram; Park, Peter J.; Jaffe, Andrew E.; Pevsner, Jonathan; Sestan, Nenad; Vaccarino, Flora M.; Mills, Ryan E.; Fasching, Liana Article ISI SCIENCE (2017)
Single Cell CNV Detection in Human Neuronal Nuclei Wierman, M.B.; Burbulis, I.E.; Chronister, W.D.; Bekiranov, S.; McConnell, M.J. Article Methods in Neurosciences (2017)
Detection of pathogen-specific antibodies by loop-mediated isothermal amplification Burbulis, I.E.; Yamaguchi, K.; Nikolskaia, O.V.; Prigge, S.T.; Magez, S.; Bisser, S.; Reller, M.E.; Grab, D.J. Article Clinical and Vaccine Immunology (2015)
Detection of Pathogen-Specific Antibodies by Loop-Mediated Isothermal Amplification Burbulis, Ian E.; Yamaguchi, Kumiko; Nikolskaia, Olga V.; Prigge, Sean T.; Magez, Stefan; Bisser, Sylvie; Reller, Megan E.; Grab, Dennis J.; Wilkins, P. P. Article Clinical and Vaccine Immunology (2015)
Multiplex protein detection with DNA readout via mass spectrometry Flanigon, James; Kamali-Moghaddam, Masood; Burbulis, Ian; Annink, Carla; Steffen, Martin; Oeth, Paul; Brent, Roger; van den Boom, Dirk; Landegren, Ulf; Cantor, Charles Article New Biotechnology (2013)
Multiplex protein detection with DNA readout via mass spectrometry 10. Flanigon, J.; Kamali-Moghaddam, M.; Burbulis I.E.; Annink, C.; Steffen, M.; Oeth, P.; Brent, R.; van den Boom, D.; Landegren, U.; Cantor, C. Article NATURE BIOTECHNOLOGY (2013)
Reagents for investigating MAPK signalling in model yeast species Pincus, D.; Benjamin, K.; Burbulis, I.E.; Tsong, A.E.; Resnekov, O. Article YEAST (2010)
Reagents for investigating MAPK signalling in model yeast species Pincus, David; Benjamin, Kirsten; Burbulis, Ian; Tsong, Annie E.; Resnekov, Orna Article Yeast (2010)
The Alpha Project: a model system for systems biology research Colman-Lerner, A.; Lok, L.; Holl, M.; Endy, D.; Tsong, A.E.; Andrews, S.S.; Brent, R.; Benjamin, K.R.; Pesce, C.G.; Serra, E.; Yu, R.C.; Bruck, J.; Burbulis, I.E.; Resnekov, O.; Abola, A.P.; Gordon, A.; Smith, R.D.; Thomson, T.M. Article IET Systems Biology (2008)
The Alpha Project: a model system for systems biology research Yu, R.C.; Resnekov, O.; Abola, A.P.; Andrews, S.S.; Benjamin, K.R.; Bruck, J.; Burbulis, I.E.; Colman-Lerner, A.; Endy, D.; Gordon, A.; Holl, M.; Lok, L.; Pesce, C.G.; Serra, E.; Smith, R.D.; Thomson, T.M.; Tsong, A.E.; Brent, R. Article IET Systems Biology (2008)
Quantifying small numbers of antibodies with a 'near-universal' protein-DNA chimera Burbulis. I.E.; Yamaguchi, K.; Yu, R.; Resnekov, O.; Brent, R. Article NATURE METHODS (2007)
Quantifying small numbers of antibodies with a 'near-universal' protein-DNA chimera Burbulis, Ian; Yamaguchi, Kumiko; Yu, Richard; Resnekov, Orna; Brent, Roger Article NATURE METHODS (2007)
LAMP for Tadpoles Burbulis, I.E.; and Brent, R. Article NATURE METHODS (2005)
Reply to "Lamp for tadpoles" Brent, Roger; Burbulis, Ian Article NATURE METHODS (2005)
Using protein-DNA chimeras to detect and count small numbers of molecules Burbulis, I.E.; Yamaguchi, K.; Carlson, R.; and Brent, R. Article NATURE METHODS (2005)
Using protein-DNA chimeras to detect and count small numbers of molecules Burbulis, Ian; Yamaguchi, Kumiko; Gordon, Andrew; Carlson, Robert; Brent, Roger Article NATURE METHODS (2005)
Disruption of specific flavonoid genes enhances the accumulation of flavonoid enzymes and end-products in Arabidopsis seedlings Pelletier, M.K.; Burbulis, I.E.; Shirley, B.W. Article PLANT MOLECULAR BIOLOGY (1999)
Disruption of specific flavonoid genes enhances the accumulation of flavonoid enzymes and end-products in Arabidopsis seedlings Pelletier, M.K.; Burbulis, I.E.; Winkel-Shirley, B. Article PLANT MOLECULAR BIOLOGY (1999)
Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway Burbulis, I.E.; Winkel-Shirley, B. Article PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1999)
Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway Burbulis, I. E.; Winkel-Shirley, B. Article Proceedings of the National Academy of Sciences (1999)
A Null Mutation in the First Enzyme of Flavonoid Biosynthesis Does Not Affect Male Fertility in Arabidopsis Burbulis, I. E. Article Plant Cell (1996)
A null mutation in the first enzyme of flavonoid biosynthesis does not affect male fertility in Arabidopsis Burbulis, I.E.; Iacobucci, M.; Shirley, B.W. Article PLANT CELL (1996)
Are flavonoids synthesized by a multi-enzyme complex? Burbulis I.E.; Pelletier M.K.; Cain C.C.; Shirley B.W. Article Southern Association of Agricultural Scientists Bullitin of Biochemical Biotechnology (1996)
Are flavonoids synthesized by a multi-enzyme complex? Burbulis, I.E.; Pelletier, M.K.; Cain, C.C.; Shirley, B.W. Article SAAS Bull Biochem Biotechnol. (1996)


Single Cell CNV Detection in Human Neuronal Nuclei Wierman, M.B.; Burbulis, I.E.; Chronister, W.D.; Bekiranov, B.; McConnell, M.J. BookSection (2017)


Development of camelid nanobody based-LAMPole diagnostic tests for dengue and Zika viruses Magez, Stefan; Grab, Dennis J. ConferencePoster (2018)


Chimeric fusion molecule for analyte detection and quantitation Burbulis, I.E.; Carlson, R.H. Patent (2006)
Protein finger print system and related methods Carlson, R.H.; Burbulis, I.E.; Brent, R. Patent (2003)


LAMPoles for Dengue Diagnosis NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (7R21AI111072-02) Proyecto 2015-2019 Coinvestigador(a)
Genome and Transcriptome measurement in Single Cells McDonnell Foundation (007) Proyecto 2014-2016 Inv. Principal
Ultra-sensitive quantitative measurements of transcripts and antigens associated with prostate cancer VTT Research fund (001) Proyecto 2010-2011 Investigador(a)
PCR for carbohydrate cancer biomarkers National Cancer Institute (R21 CA140143) Proyecto 2009-2012 Inv. Principal
The tadpole assay multiplex platform for biodefense agent diagnostics National Institute of Allergy and Infectious Diseases (U54 AI057156) Proyecto 2009-2012 Investigador(a)
Development of diagnostic reagents for the detection of Francisella and Francisella infection National Institute of Allergy and Infectious Diseases (U54 AI057156) Proyecto 2007-2009 Investigador(a)
Tadpole assays for proteomic detection of early cancer Canary Foundation (001) Proyecto 2007-2008 Investigador(a)
Tadpole Assays for the Molecular Assessment of Cancer National Cancer Institute (R33 CA114306) Proyecto 2006-2009 Inv. Principal

Ian Burbulis

Academic Professor Regular

Medicina

Universidad San Sebastian

Puerto Montt, Chile

FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Romina Bertinat

Technician

Farmacología

Universidad de Concepcion

Concepción, Chile

Gerardo Gonzalez

Full Professor

Microbiology

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Ian Burbulis

Líneas de Investigación

Educación

Biologia y Química, VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY. Estados Unidos, 1995

Biología molecular y genética, VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY. Estados Unidos, 1998

Experiencia Académica

Assistant Professor: Department of Biochemistry and Molecular Genetics Part Time

Profesor y Investigador: Departamento de medicina Full Time

Experiencia Profesional

Becaria de investigación

Instructor de programa: Programa de pasantías de minorías insuficientemente representadas

Investigador Senior

Radiación y oficial de seguridad de producto químico

Instructor de programa: Programa de pasantías de minorías insuficientemente representadas

Asesor científico

Miembro fundador: Miembro del Comité Ejecutivo

Investigador completo

Miembro fundador: Investigador completo

Referee

Referee

Review Panelist: SBIR/STTR Bioprocessing Enhancement

Review Panelist: Innovative Molecular Analysis Technologies

Editorial Board Member: Organic Chemistry

Co-Instructor: Single-Cell Analysis Course

Premios y Distinciones

McDonnell Fellowship

McDonnell Fellowship

Gordon Conference travel award

Best Student Paper / Presentation

Sigma Xi Grants-in-Aid-of-Research Funding

Graduate Research Development Program Funding

Graduate Travel Award to host Paul Srere, Ph.D.

Phi Beta Kappa

Sigma Xi Grants in Aid of Research Funding

Fairfax County Medical Society Scholarship

Distinguished University Academic Honors

Article (33)

BookSection (1)

ConferencePoster (1)

Patent (2)

Proyecto (8)

LAMPoles for Dengue Diagnosis

Genome and Transcriptome measurement in Single Cells

Ultra-sensitive quantitative measurements of transcripts and antigens associated with prostate cancer

PCR for carbohydrate cancer biomarkers

The tadpole assay multiplex platform for biodefense agent diagnostics

Development of diagnostic reagents for the detection of Francisella and Francisella infection

Tadpole assays for proteomic detection of early cancer

Tadpole Assays for the Molecular Assessment of Cancer