Man

Vicente Spiro Valenzuela Paterakis

Investigador postdoctoral

Instituto de Neurociencia Biomédica

Santiago, Chile

Líneas de Investigación


Neurociencias; Enfermedades Neurodegenerativas; Estrés de retículo endoplasmático; Terapia génica; Esclerosis lateral amiotrófica.

Educación

  •  Programa de Doctorado en Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2016
  •  Biología Celular Molecular y Neurociencias, UNIVERSIDAD DE CHILE. Chile, 2012
  •  Ingeniero en Biotecnología Molecular, UNIVERSIDAD DE CHILE. Chile, 2009

Experiencia Académica

  •   Ayudante TPA Part Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2013 - 2015

  •   Profesor Asistente Part Time

    UNIVERSIDAD PEDRO DE VALDIVIA

    Medicina

    Santiago, Chile

    2013 - A la fecha

Experiencia Profesional

  •   Asistente de Investigación

    Universidad de Chile

    Chile

    2011 - 2012

  •   Monitor de TPA en curso Fisiología para estudiantes de Medicina

    Universidad de Chile

    Chile

    2013 - 2015

  •   Assistant professor

    Universidad Pedro de Valdivia

    Chile

    2013 - 2013


 

Article (12)

ALS-linked protein disulfide isomerase variants cause motor dysfunction.

Woehlbier, Ute; Colombo, Alicia; Saaranen, Mirva J; Pérez, Viviana; Ojeda, Jorge; Bustos, Fernando J; Andreu, Catherine I; Torres, Mauricio; Valenzuela, Vicente; Medinas, Danilo B; Rozas, Pablo; Vidal, Rene L; Lopez-Gonzalez, Rodrigo; Salameh, Johnny; Fernandez-Collemann, Sara; Muñoz, Natalia; Matus, Soledad; Armisen, Ricardo; Sagredo, Alfredo; Palma, Karina; Irrazabal, Thergiory; Almeida, Sandra; Gonzalez-Perez, Paloma; Campero, Mario; Gao, Fen-Biao; Henny, Pablo; van Zundert, Brigitte; Ruddock, Lloyd W; Concha, Miguel L; Henriquez, Juan P; Brown, Robert H; Hetz, Claudio

Article
The EMBO journal  (2016)

Gene therapy to target ER stress in brain diseases

Valenzuela, V; Martinez, G; Duran-Aniotz, C; hetz, C

Article ISI SCOPUS
BRAIN RESEARCH  (2016)

Gene therapy to target ER stress in brain diseases.

Valenzuela, Vicente; Martínez, Gabriela; Duran-Aniotz, Claudia; Hetz, Claudio

Article
Brain research  (2016)

Injury to the nervous system: A look into the ER.

Valenzuela, Vicente; Oñate, Maritza; Hetz, Claudio; Court, Felipe A

Article
Brain research  (2016)

A new method to measure autophagy flux in the nervous system.

Matus, Soledad; Valenzuela, Vicente; Hetz, Claudio

Article
Autophagy  (2014)

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis.

Nassif, Melissa; Valenzuela, Vicente; Rojas-Rivera, Diego; Vidal, René; Matus, Soledad; Castillo, Karen; Fuentealba, Yerko; Kroemer, Guido; Levine, Beth; Hetz, Claudio

Article
Autophagy  (2014)

Sprouting of axonal collaterals after spinal cord injury is prevented by delayed axonal degeneration.

Collyer, E; Catenaccio, A; Lemaitre, D; Diaz, P; Valenzuela, V; Bronfman, F; Court, F A

Article
Experimental neurology  (2014)

ER Dysfunction and Protein Folding Stress in ALS.

Matus, Soledad; Valenzuela, Vicente; Medinas, Danilo B; Hetz, Claudio

Article
International journal of cell biology  (2013)

Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis.

Matus, Soledad; Lopez, Estefanía; Valenzuela, Vicente; Nassif, Melissa; Hetz, Claudio

Article
PloS one  (2013)

Measurement of autophagy flux in the nervous system in vivo.

Castillo, K; Valenzuela, V; Matus, S; Nassif, M; Oñate, M; Fuentealba, Y; Encina, G; Irrazabal, T; Parsons, G; Court, F A; Schneider, B L; Armentano, D; Hetz, C

Article
Cell death & disease  (2013)

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.

Castillo, Karen; Nassif, Melissa; Valenzuela, Vicente; Rojas, Fabiola; Matus, Soledad; Mercado, Gabriela; Court, Felipe A; van Zundert, Brigitte; Hetz, Claudio

Article
Autophagy  (2013)

Activation of the unfolded protein response enhances motor recovery after spinal cord injury.

Valenzuela, V; Collyer, E; Armentano, D; Parsons, G B; Court, F A; Hetz, C

Article
Cell death & disease  (2012)

Review (2)

Proteostasis disturbance in amyotrophic lateral sclerosis

Medinas, DB; Valenzuela, V; hetz, C

Review ISI SCOPUS
Human Molecular Genetics  (2017)

Injury to the nervous system: A look into the ER

Valenzuela, V; Onate, M; hetz, C; Court, FA

Review ISI SCOPUS
BRAIN RESEARCH  (2016)

3
Vicente Valenzuela

Investigador postdoctoral

Instituto de Neurociencia Biomédica

Santiago, Chile

2
Felix Diaz

1
Felipe Court

Full Professor and Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

1
Danilo Bilches

Staff Scientist

Instituto de Neurociencia Biomedica

Santiago, Chile