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Assaf Katz Zondek

Profesor Asistente

Universidad de Chile

Santiago, Chile

Nuestro grupo está interesado en la biología de RNA en bacterias, con énfasis en la regulación de la traducción y la evolución del uso de codones. En este contexto hemos estudiado el papel de la maquinaria traduccional en la adaptación al estrés.

Doctor en Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2010
Bioquímico, UNIVERSIDAD DE CHILE. Chile, 2005

Profesor Asistente Full Time

UNIVERSIDAD DE CHILE

Facultad de Medicina

Santiago, Chile

2017 - A la fecha
Profesor Asistente (Mediante proyecto Inserción a la Academia) Full Time

UNIVERSIDAD DE CHILE

Facultad de Medicina

Santiago, Chile

2014 - 2017
Investigador postdoctoral Full Time

OHIO STATE UNIVERSITY

Columbus. OH, Estados Unidos

2011 - 2013

Investigador postdoctoral Full Time

Ohio State University

Columbus, OH, Estados Unidos

2011 - 2013
Profesor asistente Full Time

Universidad de Chile

Santiago, Chile

2014 - A la fecha


Synonymous mutations in the phosphoglycerate kinase 1 gene induce an altered response to protein misfolding in <i>Schizosaccharomyces pombe</i> Moreira-Ramos, Sandra; Arias, Loreto; Flores, Rodrigo; Katz, Assaf; Levican, Gloria; Orellana, Omar Article ISI FRONTIERS IN MICROBIOLOGY (2023)
Whole-genome sequencing reveals changes in genomic diversity and distinctive repertoires of T3SS and T6SS effector candidates in Chilean clinical <i>Campylobacter</i> strains Katz, Assaf; Porte, Lorena; Weitzel, Thomas; Varela, Carmen; Munoz-Rehbein, Cristina; Ugalde, Juan A.; Grim, Christopher; Gonzalez-Escalona, Narjol; Blondel, Carlos J.; Bravo, Veronica Article ISI FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2023)
Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical Campylobacter jejuni and Campylobacter coli strains from Chile Bravo, Veronica; Katz, Assaf; Porte, Lorena; Weitzel, Thomas; Varela, Carmen; Gonzalez-Escalona, Narjol; Blondel, Carlos J. Article ISI PLOS NEGLECTED TROPICAL DISEASES (2021)
Modification of Transfer RNA Levels Affects Cyclin Aggregation and the Correct Duplication of Yeast Cells Arias, Loreto; Martinez, Fabian; Gonzalez, Daniela; Flores-Rios, Rodrigo; Katz, Assaf; Tello, Mario; Moreira, Sandra; Orellana, Omar Article ISI FRONTIERS IN MICROBIOLOGY (2021)
Modulation of Escherichia coli Translation by the Specific Inactivation of tRNAGly Under Oxidative Stress Leiva, Lorenzo Eugenio; Pincheira, Andrea; Elgamal, Sara; Kienast, Sandra D.; Bravo, Verónica; Leufken, Johannes; Gutiérrez, Daniela; Leidel, Sebastian A.; Ibba, Michael; Katz, Assaf Article FRONTIERS IN GENETICS (2020)
Modulation ofEscherichia coliTranslation by the Specific Inactivation of tRNA(Gly)Under Oxidative Stress Leiva, Lorenzo Eugenio; Pincheira, Andrea; Elgamal, Sara; Kienast, Sandra D.; Bravo, Veronica; Leufken, Johannes; Gutierrez, Daniela; Leidel, Sebastian A.; Ibba, Michael; Katz, Assaf Article ISI FRONTIERS IN GENETICS (2020)
Codon usage revisited: Lack of correlation between codon usage and the number of tRNA genes in enterobacteria Rojas, J; Castillo, G; Leiva, LE; Elgamal, S; Orellana, O; Ibba, M; Katz, A Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center Willi, Jessica; Küpfer, Pascal; Evéquoz, Damien; Fernandez, Guillermo; Katz, Assaf; Leumann, Christian; Polacek, Norbert Article ISI SCOPUS NUCLEIC ACIDS RESEARCH (2018)
Non-canonical roles of tRNAs and tRNA mimics in bacterial cell biology. Katz, Assaf; Elgamal, Sara; Rajkovic, Andrei; Ibba, Michael Article MOLECULAR MICROBIOLOGY (2016)
EF-P Dependent Pauses Integrate Proximal and Distal Signals during Translation Elgamal, Sara; Katz Assaf, Hersch; Steven J, Newsom; David, White; Peter, Navarre; William Wiley, Ibba Michael Article PLoS Genetics (2014)
Molecular evolution of protein-RNA mimicry as a mechanism for translational control. Katz, Assaf; Solden, Lindsey; Zou, S Betty; Wiley Navarre, William; Ibba, Michael Article Nucleic acids research (2014)
The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation. Kobayashi, Kan; Katz, Assaf; Rajkovic, Andrei; Ishii, Ryohei; Branson, Owen E; Freitas, Michael A; Ishitani, Ryuichiro; Ibba, Michael; Nureki, Osamu Article Nucleic acids research (2014)
Translation initiation rate determines the impact of ribosome stalling on bacterial protein synthesis Hersch, Steven J.; Elgamal, Sara; Katz, Assaf; Ibba, Michael; Navarre, William Wiley Article The Journal of biological chemistry (2014)
A pseudo-tRNA modulates antibiotic resistance in Bacillus cereus. Rogers, Theresa E; Ataide, Sandro F; Dare, Kiley; Katz, Assaf; Seveau, Stephanie; Roy, Hervé; Ibba, Michael Article PloS one (2012)
Glutamyl-tRNA in Bacteria. Multiple Identities for Multiple Functions Katz A., Orellana o. Article Croatica Chemica Acta (2012)
ICE Afe 1, an actively excising genetic element from the biomining bacterium Acidithiobacillus ferrooxidans. Bustamante, Paula; Covarrubias, Paulo C; Levicán, Gloria; Katz, Assaf; Tapia, Pablo; Holmes, David; Quatrini, Raquel; Orellana, Omar Article Journal of molecular microbiology and biotechnology (2012)
Cellular levels of heme affect the activity of dimeric glutamyl-tRNA reductase de Armas-Ricard M., Katz A; Orellana O., Levicán G.; Moser, J Article Biochemical and Biophysical Research Communications (2011)
Î²-Lysine discrimination by lysyl-tRNA synthetase. Gilreath, Marla S; Roy, Hervé; Bullwinkle, Tammy J; Katz, Assaf; Navarre, William W; Ibba, Michael Article FEBS letters (2011)
Redox status affects the catalytic activity of glutamyl-tRNA synthetase Katz A, Banerjee R.; de Armas, M; Ibba M., Orellana O. Article Biochemical and Biophysical Research Communications (2010)
A 300 kpb genome segment, including a complete set of tRNA genes, is dispensable for Acidithiobacillus ferrooxidans Levicán, Gloria; Katz, Assaf; Valdés, Jorge; Quatrini, Raquel; Holmes David S., Orellana Article Advanced Materials Research (2009)
Regulation of a glutamyl-tRNA synthetase by the heme status Levican, G; Katz A., de Armas M.; Nunez, H Article PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A tRNA(Glu) that uncouples protein and tetrapyrrole biosynthesis Levican, G; Katz A., Valenzuela; P, Soll D. Article FEBS LETTERS (2005)


Protein Synthesis and the Stress Response Katz, Assaf; Orellana, Omar; Biyani, Manish BookSection (2012)


Concurso de proyectos de enlace con concurso Fondecyt regular, VID 2018 "Role of translation regulation in the pathogenesis and environmental adaptation of enterobacteria". Universidad de Chile (ENL05/18) Proyecto 2018-2019 Inv. Principal
RNA salon Universidad de Chile RNA Society (sin folio) Proyecto 2016-2017 Director(a)
NON-CODING RNAS AND TRANSLATION EFFICIENCY COORDINATELY CONTRIBUTE TO THE REGULATORY NETWORKS THAT CONTROL GLOBAL GENE EXPRESSION IN BACTERIA. FONDECYT (1150834) Proyecto 2015-2019 Coinvestigador(a)
EFFECTS OF OXIDATIVE STRESS ON BACTERIAL TRANSLATION FONDECYT (11140222) Proyecto 2014-2017 Inv. Responsable
Proyecto CONICYT de inserción a la academia "Fortalecimiento de líneas de investigación en Genómica, Bioquímica y Biología Molecular de Microorganismos" PAI (79130044) Proyecto 2014-2016 Investigador(a)
Biochemistry of Lysyl-tRNA synthetase National Institutes of Health (NIH) (2R01 GM065183) Proyecto 2011-2013 Postdoctorado
PROGRAMA DE PASANTÍAS EN EL EXTRANJERO PARA BECARIOS DE DOCTORADO (2DO SEMESTRE) - 2007 PFCHA (28070050) Proyecto 2008-2008 Inv. Responsable
PARTICIPACION DE LAS GLUTAMIL-tRNA SINTETASAS EN FUNCIONES ALTERNATIVAS A LA BIOSINTESIS DE PROTEINAS=> BIOSINTESIS DE TETRAPIRROLES Y/O GLUTAMINA. FONDECYT (1070437) Proyecto 2007-2010 Tesista
Doctorado en Ciencias Biomédicas PFCHA (21050408) Proyecto 2005-2009 Inv. Responsable
POSIBLE PARTICIPACION DE COMPLEJOS RIBONUCLEOPROTEICOS EN LA CANALIZACION (DESTINACION) DEL tRNA HACIA LA SINTESIS DE ACIDO d-AMINO LEVULINICO Y DE AMINOACIL-tRNA EN ACIDITHIOBACILLUS FERROOXIDANS. FONDECYT (1020087) Proyecto 2002-2005 Tesista