Luis Alberto Cordova Jara


Universidad de Chile

Santiago , Chile

Líneas de Investigación

Micro-ambiente óseo y osteolísis: aplicación al aflojamiento aséptico peri-protésico de implantes articulares totales 2010-2014 Immunomodulation of osteogenesis 2014-2016 Wnt signaling pathway in bone grafting 2016-2017


  •  Cirujano Dentista , UNIVERSIDAD DE CHILE. Chile, 1996
  •  Especialista Cirugia y Traumatologia Maxilofacial , UNIVERSIDAD DE CHILE. Chile, 2002
  •  Biomedicina , UNIVERSIDAD DE CHILE. Chile, 2010
  •  Biomedicina Biología ósea , UNIVERSITE DE NANTES. Francia, 2014
  •  Postdoctoral Fellow, STANFORD UNIVERSITY. Estados Unidos, 2017

Experiencia Académica

  •   Profesor Full Time



    Santiago, Chile

    2001 - A la fecha

Experiencia Profesional

  •   Especialista Cirugia Maxilofacial Part Time

    Hospital San Jose


    2004 - A la fecha


Article (20)

Dysregulated healing response participates in the pathophysiology of temporomandibular joint ankylosis
Osteoimmunology drives dental implant osseointegration: A new paradigm for implant dentistry
Histatin-1 counteracts the cytotoxic and antimigratory effects of zoledronic acid in endothelial and osteoblast-like cells
Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery
A WNT protein therapeutic improves the bone-forming capacity of autografts from aged animals
CCL2, CCL5, and IGF-1 participate in the immunomodulation of osteogenesis during M1/M2 transition in vitro
Mutant CCL2 protein coating mitigates wear particle-induced bone loss in a murine continuous polyethylene infusion model
Orthopaedic wear particle-induced bone loss and exogenous macrophage infiltration is mitigated by local infusion of NF-kappa B decoy oligodeoxynucleotide
Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway
Relationships among Bone Quality, Implant Osseointegration, and Wnt Signaling
Aging Affects Bone Marrow Macrophage Polarization: Relevance to Bone Healing
Decreased osteogenesis in mesenchymal stem cells derived from the aged mouse is associated with enhanced NF-B activity
NF-kappa B decoy oligodeoxynucleotide mitigates wear particle-associated bone loss in the murine continuous infusion model
Pro-osteoclastic in vitro effect of Polyethylene-like nanoparticles: Involvement in the pathogenesis of implant aseptic loosening
Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw
The effects of immunomodulation by macrophage subsets on osteogenesis in vitro
Are Fluorescent Organic Nanoparticles Relevant Tools for Tracking Cancer Cells or Macrophages?
Inhibition of osteolysis and increase of bone formation after local administration of siRNA-targeting RANK in a polyethylene particle-induced osteolysis model
Giant canine with dentine anomalies in oculo-facio-cardio-dental syndrome
Medial proximal tibia donor site: Contribution to alveolar cleft repair in children

BookWhole (1)

NF-kappa B as a Therapeutic Target in Inflammatory-Associated Bone Diseases

JournalWhole (1)

Antiangiogenic Effect of Triamcinolone Associated with Lidocaine with Epinephrine for Dental use in Chicken Chorioallantoic Membrane

Proyecto (10)

Habilitación de una Unidad de Microcirugía Experimental en el Bioterio de Facultad de Odontología de la Universidad de Chile.
Immunomodulating bone healing for the aging via macrophages - osteoprogenitor cells interaction
Wnt signaling pathway in bone grafting
Wnt signaling pathway in bone grafting
Immunomodulation of osteogenesis
Immunomodulation of osteogenesis
Caracterización histológica e inmuhistoquímica de muestras humanas de anquilosis temporomandibular
Développement d'un modèle animal murin pour l'étude de la phsyiopathologie de l'ostéonécrose des maxillaires => applications aux bisphosphonates et aux inhibiteurs e RANKL (ONMLBP)
Micro-ambiente óseo y osteolísis=> aplicación al aflojamiento aséptico peri-protésico de implantes articulares totales
Micro-ambiente óseo y osteolísis=> aplicación al aflojamiento aséptico peri-protésico de implantes articulares totales

Review (5)

Osteoimmunology of Oral and Maxillofacial Diseases: Translational Applications Based on Biological Mechanisms
The biological response to orthopedic implants for joint replacement. II: Polyethylene, ceramics, PMMA, and the foreign body reaction
Inflammation, fracture and bone repair
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery
Orthopaedic implant failure: aseptic implant loosening - the contribution and future challenges of mouse models in translational research
Luis Cordova


Universidad de Chile

Santiago , Chile

Julio Villanueva

Profesor Títular

CIrugía y Traumatología Bucal y Maxilofacial

Universidad de Chile. Facultad de Odontología

Santiago, Chile

Rolando Vernal

Profesor Titular

Departamento de Odontología Conservadora


Santiago, Chile

Pedro Torres

Ayudante laboratorio

Universidad de Chile

Santiago, Chile

Vicente Torres

Associate Professor

Institute for Research in Dental Sciences


Santiago, Chile

Luis Solano

Asistente de investigación

Universidad de Chile

Santiago, Chile