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Octavio Andrés Orellana Serradell

Investigador

CCHEN

Santiago, Chile

Cáncer Progresión y desarrollo tumoral Migración celular Inflamación Dinámicas inter-organelares Calcio Interacciones proteína-proteína Respuesta celular al daño

Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2018
Bioquímico, UNIVERSIDAD DE CHILE. Chile, 2010

Profesor Asistente cursos de Inglés para Posgrado Part Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2019 - A la fecha
Profesor Asistente Part Time

UNIVERSIDAD SANTO TOMAS

Medicina

Chile

2025 - A la fecha

Investigador Postdoctoral Full Time

Laboratorio Oncología Celular y Molecular

Santiago, Chile

2017 - 2018
Investigador Postdoctoral Full Time

Laboratorio Inmunidad Innata

Chile

2018 - 2020
Investigador Postdoctoral Full Time

MINICAD

Chile

2020 - 2024
Investigador Full Time

CCHEN

Chile

2025 - A la fecha


Rhotekin-1 is a novel interacting protein and regulator of TRPC6 activity Lavanderos, Boris; Orellana-Serradell, Octavio; Maureira, Diego; Cruz, Pablo; Silva, Ian; Toledo, Jorge; Gonzalez-Avendano, Mariela; Lopez, Joaquin; Santos, Rodrigo; Arancibia, Felipe; et al. Article ISI FEBS JOURNAL (2025)
Overexpression of REST Represses the Epithelial-Mesenchymal Transition Process and Decreases the Aggressiveness of Prostate Cancer Cells Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2024)
The Cytoplasmic Region of SARAF Reduces Triple-Negative Breast Cancer Metastasis through the Regulation of Store-Operated Calcium Entry Cruz, Pablo; Pinto, Raquel; Cerda Oscar Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Regulation of the Intestinal Extra-Adrenal Steroidogenic Pathway Component LRH-1 by Glucocorticoids in Ulcerative Colitis Molina, Hector; Lubascher, Jaime; MONTECINO-LEONARD, MARTIN ALEJANDRO; QUERA-PINO, RODRIGO ENRIQUE Article ISI SCOPUS Cells (2022)
TRP Channels Interactome as a Novel Therapeutic Target in Breast Cancer Cruz, Pablo; Torres, Camila; Cerda Oscar Article ISI FRONTIERS IN ONCOLOGY (2021)
Does Peer Reviewing for COVID-19-Related Papers Still Work? Orellana-Serradell, Octavio; Díaz, Magda C.; Gonzalez, Maria Fernanda; Gutiérrez, Myriam; Herrera, Daniela; Jara, Daniela; Maureira, Diego; Ruiz-Fuentes, J. L.; Sanhueza, Sofia; LEYTON-CAMPOS, LISETTE Article SCOPUS Frontiers in Research Metrics and Analytics (2020)
SNAIL expression correlates with the translocation of syndecan-1 intracellular domain into the nucleus in prostate cancer cell lines Cubillos P.; GarcÃa De Herreros A. Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
TRP Channels Regulation of Rho GTPases in Brain Context and Diseases CRUZ-JOHNSON, PABLO CHRISTIAN; CERDA-ARANCIBIA, OSCAR ALEJANDRO Article ISI SCOPUS Frontiers in Cell and Developmental Biology (2020)
Interleukin 33/ST2 Axis Components Are Associated to Desmoplasia, a Metastasis-Related Factor in Colorectal Cancer de la Fuente Lopez, Marjorie; Orellana-Serradell, Octavio; Sepulveda, Santiago A.; Salazar, Christian; Parada-Venegas, Daniela; Simian, Daniela; Kronberg, Udo; Abedrapo, Mario; Pena, Cristina Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2019)
Silencing of the transcriptional factor ZEB1 alters the steroidogenic pathway, and increases the concentration of testosterone and DHT in DU145 cells Villar, P.; Paciucci, R.; Castellon, E. A.; Contreras, H. R. Article ISI SCOPUS ONCOLOGY REPORTS (2019)
The transcription factor ZEB1 promotes chemoresistance in prostate cancer cell lines Octavio Orellana-Serradell, Daniela Herrera, Enrique A Castellón, Héctor R Contreras Article ISI ASIAN JOURNAL OF ANDROLOGY (2019)
The transcription factor ZEB1 promotes an aggressive phenotype in prostate cancer cell lines Contreras, HR Article ISI SCOPUS ASIAN JOURNAL OF ANDROLOGY (2018)
Proapoptotic effect of endocannabinoids in prostate cancer cells Orellana Serradell O; Poblete, CE; Sánchez, C; Gallegos, I.; Huidobro C.; Contreras, HR Article ISI SCOPUS ONCOLOGY REPORTS (2015)


ZEBI as a key promoter of tumoral progress in advanced stages of prostate cancer Orellana-Serradell, O Abstract ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Suppression of SDC-1 expression by overexpression of ZEB1/ZEB2 in prostate cancer cells Contreras H.; Farfan, N; Orellana Serradell O; Chrzanowsky D.; Castellón E. Abstract ISI EUROPEAN JOURNAL OF CANCER (2015)


Regulation of the activity and localization of TRPC6 channels by VAPA and its role in cancer progression Orellana Octavio; Cerda Oscar Proyecto (2021)
Role of Cortisol Signaling on intestinal steroidogenesis in ulcerative colitis FONDECYT (1170648) Proyecto 2018-2021 Postdoctorado
The transcription factors ZEB1/SNAIL induce in vitro cell malignancy and cancer stem cell phenotype through epithelial-mesenchymal transition in prostate cells, increasing androgen synthesis capacity and resistance FONDECYT (1151214) Proyecto 2015-2019 Tesista
EXPRESSION OF SYNDECANS IS DOWN REGULATED BY TRANSCRIPTION FACTOR SNAIL DURING EPITHELIAL MESENCHYMAL TRANSITION IN PROSTATE CANCER FONDECYT (1110269) Proyecto 2011-2015 Investigador(a)


The odyssey of the TR(i)P journey to the cellular membrane Rivera, Bastian; Brauchi, Sebastian; Cerda Oscar Review ISI FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2024)

1

Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1

Catherine Sanchez

Clinical Researcher

Dirección Académica

CLÍNICA LAS CONDES

Santiago, Chile

8

Hector Contreras

Academico

Oncologia Basico Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

7

Enrique Castellón

Profesor Titular.

Oncología Básico-Clínica

UNIVERSIDAD DE CHILE

Santiago, Chile

1

Monica Caceres

Profesor asociado

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

2

Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

1

Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

2

IVAN GALLEGOS

PATHOLOGIST, LABORATORY DIRECTOR

PATHOLOGY

HOSPITAL CLINICO DE UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1

Glauben Landskron

Assistant Professor

Departamento de Tecnología Médica

Universidad de Chile

Santiago, Chile

1

Daniela Parada

Asistente de investigación

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

1

María José Torres

Docente

Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

1

Santiago Sepúlveda

Profesional Tecnólogo Médico

Anatomía Patológica

Pontificia Universidad Católica de Chile

Santiago, Chile

1

Nancy Farfán

Post-doc.

Farmacología

Universidad de Chile

Santiago, Chile

17

Octavio Orellana

Investigador

P2mc

CCHEN

Santiago, Chile

1

Paulina Villar

Tesista doctorado en bioquímica

Bioquímica

Universidad de Chile

Santiago, Chile

1

Sebastián Indo

Assistant Professor

Department of Medical Technologist

Universidad de Chile

Santiago, Chile

4

Daniela Herrera