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Octavio Andrés Orellana Serradell

Investigador Postdoctoral

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Cáncer Progresión y desarrollo tumoral Migración celular Inflamación Dinámicas inter organelares Calcio Interacciones proteína-proteína

Educación

  •  Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2018
  •  Bioquímico, UNIVERSIDAD DE CHILE. Chile, 2010

Experiencia Académica

  •   Ayudante del Curso de Inglés para Doctorados Other

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2019 - A la fecha

Experiencia Profesional

  •   Investigador Postdoctoral Full Time

    Laboratorio Oncología Celular y Molecular

    Santiago, Chile

    2017 - 2018

  •   Investigador Postdoctoral Full Time

    Laboratorio Inmunidad Innata

    Chile

    2018 - 2020

  •   Investigador Postdoctoral Full Time

    MINICAD

    Chile

    2020 - A la fecha


 

Article (11)

The Cytoplasmic Region of SARAF Reduces Triple-Negative Breast Cancer Metastasis through the Regulation of Store-Operated Calcium Entry
Regulation of the Intestinal Extra-Adrenal Steroidogenic Pathway Component LRH-1 by Glucocorticoids in Ulcerative Colitis
TRP Channels Interactome as a Novel Therapeutic Target in Breast Cancer
DOES PEER REVIEWING FOR COVID-19-RELATED PAPERS STILL WORK?
SNAIL expression correlates with the translocation of syndecan-1 intracellular domain into the nucleus in prostate cancer cell lines
TRP Channels Regulation of Rho GTPases in Brain Context and Diseases
Interleukin 33/ST2 Axis Components Are Associated to Desmoplasia, a Metastasis-Related Factor in Colorectal Cancer
Silencing of the transcriptional factor ZEB1 alters the steroidogenic pathway, and increases the concentration of testosterone and DHT in DU145 cells
The transcription factor ZEB1 promotes chemoresistance in prostate cancer cell lines
The transcription factor ZEB1 promotes an aggressive phenotype in prostate cancer cell lines
Proapoptotic effect of endocannabinoids in prostate cancer cells

Abstract (1)

Suppression of SDC-1 expression by overexpression of ZEB1/ZEB2 in prostate cancer cells

Proyecto (4)

Regulation of the activity and localization of TRPC6 channels by VAPA and its role in cancer progression
Role of Cortisol Signaling on intestinal steroidogenesis in ulcerative colitis
The transcription factors ZEB1/SNAIL induce in vitro cell malignancy and cancer stem cell phenotype through epithelial-mesenchymal transition in prostate cells, increasing androgen synthesis capacity and resistance
EXPRESSION OF SYNDECANS IS DOWN REGULATED BY TRANSCRIPTION FACTOR SNAIL DURING EPITHELIAL MESENCHYMAL TRANSITION IN PROSTATE CANCER
13
Octavio Orellana

Investigador Postdoctoral

ICBM

Universidad de Chile

Santiago, Chile

7
Hector Contreras

Academico

Oncologia Basico Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

6
Enrique Castellón

Profesor Titular.

Oncología Básico-Clínica

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

2
IVAN GALLEGOS

PATHOLOGIST, LABORATORY DIRECTOR

PATHOLOGY

HOSPITAL CLINICO DE UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1
María José Torres

Docente

Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Daniela Parada

Asistente de investigación

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

1
Nancy Farfán

Post-doc.

Farmacología

Universidad de Chile

Santiago, Chile

1
Santiago Sepúlveda

Profesional Tecnólogo Médico

Anatomía Patológica

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Glauben Landskron

Academic Researcher

Escuela de Medicina

Universidad Finis Terrae

Santiago, Chile

1
Paulina Villar

Tesista doctorado en bioquímica

Bioquímica

Universidad de Chile

Santiago, Chile

1
Monica Caceres

Profesor asociado

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

1
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Catherine Sanchez

Clinical Researcher

Dirección Académica

CLÍNICA LAS CONDES

Santiago, Chile