Man

Francisco José Mardones Santander

Profesor Titular

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE SALUD PÚBLICA

Santiago, Chile

Líneas de Investigación


OBESIDAD INFANTIL, COMPLICACIONES METABOLICAS Y RIESGO CARDIOVASCULAR Y PREVENCION; NUTRICION EN ENFERMEDADES CRONICAS INFANTILES; DISLIPIDEMIAS EN LA NIÑEZ; PREVENCION CARDIOVASCULAR PEDIATRICA; ORIGEN FETAL DEL SINDROME METABOLICO; ESTUDIO DE LA ARTERIOSCLEROSIS SUBCLINICA EN LA EDAD PEDIATRICA; Nutrición y salud materno-infantil; Mecanismos moleculares de programación intrauterina; Rol fisiopatológico del estrés celular en ginecología y obstetricia; relación entre alimentación y enfermedades cardiovasculares; origen temprano de las enfermedades cronicas; Salud Pública; Ciencias Comunitarias; Prevención de VIH y Sida, Salud de la Mujer; Salud pública y nutrición materno-infantil; Origen temprano de las enfermedades crónicas; Crecimiento fetal: estudios peso al nacer y mortal.; Modelamiento de epidemias: VIH-SIDA, otras enfermedades.; Modelo de efectos mixtos y análisis de conglomerados; Minería de datos

Educación

  •  Medico, UNIVERSIDAD DE CHILE. Chile, 1971
  •  Sciences, UNIVERSIDAD DE LONDRES. Reino Unido, 1976

Experiencia Académica

  •   Médico General Full Time

    MINISTERIO DE SALUD

    Santiago, Chile

    1971 - 1973

  •   Profesor Full Time

    UNIVERSIDAD DE CHILE

    Santiago, Chile

    1977 - 1990

  •   Especialista en Salud Full Time

    WORLD BANK

    Washington, Estados Unidos

    1991 - 1992

  •   Representante Full Time

    ORGANIZACION MUNDIAL DE LA SALUD

    Bogotá, Colombia

    1993 - 1996

  •   Profesor Titular Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    1996 - A la fecha

Experiencia Profesional

  •   MEDICO GENERAL Full Time

    MINISTERIO DE SALUD

    Santiago, Chile

    1971 - 1973

  •   PROFESOR TITULAR Full Time

    PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

    SANTIAGO, Chile

    1996 - A la fecha

  •   Profesor Full Time

    UNIVERSIDAD DE CHILE

    Santiago, Chile

    1977 - 1990

  •   Especialista en Salud Full Time

    Banco Mundial

    Washington, Estados Unidos

    1991 - 1992

  •   Representante Full Time

    Organización Panamericana de la Salud

    Bogotá, Colombia

    1993 - 1996

Formación de Capital Humano


Names of my last two Magister students with thesis directed by me: Drs. Paz Pacheco and Carolina Giadach


Difusión y Transferencia


In the last three years, I have been actively investigating the obesity epidemics and proposing means to prevent it. My FONDECYT regular project 2009-2013 has provided me with an important diagnosis of the school-age children belonging to Puente Alto County, with the biggest county population in Chile. Diagnosis of obesity and overweight has been done for the first time in a controlled manner with trained personnel in this universe of children with mean age 11 years. In addition, we studied other aspects of this population: a) metabolic syndrome components; b) insulin resistance; c) carotid intima-media thickness; c) the Arginine-NO via in blood cells; e) and the early origins of obesity and other metabolic syndrome components, looking at the associations with prenatal and postnatal growth; we are using the conditional method to assess the influence of postnatal weight and height gain. Regarding the last aspect, I have been actively involved in a society that studies the obesity and chronic diseases epidemics called DOHaD society (Developmental origins of Health and Disease; www.dohadsoc.org), belonging to its directive council since 2006. I was the president of the International DOHaD congress of 2009 in Santiago, Chile, and I am now organizing, as chairman, the Ibero-American chapter of the DOHaD Society.
I have been invited to deliver lectures in Peru, Uruguay, Colombia, Argentina, USA and Spain, during different meetings. I wrote a book published in 2009 on those means from the public health point of view. I have also written different papers since 2008 in the international literature reporting results of my research, including several book chapters. Most of my publications have considered the idea of improving exercise activities in a better urban environment. One of the means to prevent obesity that I began to sustain in a publication of year 1983 has been the 6 months post-natal leave for working women that has reached a national consensus in 2012. The expected increase in breast-feeding duration should play a preventive role.


Premios y Distinciones

  •   Directive council

    Developmental Origins of Health and Disease

    Estados Unidos, 2005

    Designed Executive Board member of the Developmental Origins of Health and Disease, from 2005

  •   Chairman International DOHaD congress

    Developmental Origins of Health and Disease

    Chile, 2009

    Chairman International DOHaD congress, 2009 in Santiago Chile.


 

Article (13)

Relación médico-paciente en la Pontificia Universidad Católica de Chile: evaluación de una escala de medición
Combined influence of preconception body mass index and gestational weight gain on fetal growth
Combined influence of preconception body mass index and gestational weight gain on fetal growth Influencia combinada del índice de masa corporal pregestacional y de la ganancia de peso en el embarazo sobre el crecimiento fetal
Insulinemia e índice HOMA en niños y adolescentes chilenos
Normal plasma insulin and HOMA values among chilean children and adolescents
Normal plasma insulin and HOMA values among chilean children and adolescents Insulinemia e índice HOMA en niños y adolescentes chilenos
METHODS OF VALUATION OF THE NUTRITIONAL CONDITION
Methods of valuation of the nutritional condition Métodos de valoración del estado nutricional
The impact of emergency contraception in Public Health
Association of perinatal factors and obesity in 6-to 8-year-old Chilean children
Effects of a dairy product fortified with multiple micronutrients and omega-3 fatty acids on birth weight and gestation duration in pregnant Chilean women
Estimation of individual neonatal survival using birthweight and gestational age: A way to improve neonatal care
Maternal anemia in Concepcion province, Chile: association with maternal nutritional status and fetal growth

Abstract (2)

Metabolic Syndrome and Subclinical Atherosclerosis in Children
Prenatal Growth and Metabolic Syndrome Components in Children

BookSection (13)

A new paradigm of growth: Growth pattern 2006
Challenges of addressing overnutrition and undernutrition during pregnancy in Chile/Latin America
Fetal life and healthy growth
Nutrition policies and programs in Latin America and the Caribbean
Obesity interventions in child and adolescent, Chile
Origen temprano de las enfermedades crónicas: Implicancias en Pediatría
Neonatal morbility and mortality
Nutrition of the pregnant woman
Obesity early origin
Other analysis of promising policies and interventions to Chile
Poniendo en práctica la educación sobre dieta y ejercicio en las escuelas
Una visión general de la epidemia de obesidad en Chile y en el mundo
Neonatal mortality, definitions perinatal concepts

BookWhole (1)

Obesity What can we do?

Proyecto (5)

Intrauterine programming of hypoxia –and oxidative stress- induced vascular responses in placenta endothelium from IUGR and macrosomic fetuses: early evidence for epigenetic-driven vascular dysfunction
Maternal obesity produces insulin resistance in fetal tissues involving endoplasmic reticulum stress
International Maternal Weight Research Survey
MicroRNAs as epigenetic markers of metabolic and vascular damage in children with metabolic syndrome
Metabolic syndrome in children (fetal origin of metabolic syndrome in Chilean children. L-arginine/NO paper route as an indicator of cardiovascular risk and endothelial dysfunction),
36
Francisco Mardones

Profesor Titular

Salud Pública

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE SALUD PÚBLICA

Santiago, Chile

11
Luis Villarroel

Profesor Asociado

Salud Publica

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE SALUD PÚBLICA

Santiago, Chile

3
Salesa Barja

Médico Nutrióloga pediátrica

Gastroenterología y Nutrición Pediátrica

Pontificia Universidad Católica de Chile

Santiago, Chile

3
oscar castillo

Director Escuela

Facultad de Medicina

Universidad Finis Terrae

Santiago, Chile

3
Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

2
JOSE TAPIA

profesor titular

neonatologia

pontificia universidad católica de chile

SANTIAGO, Chile

2
Maria Urrutia

Profesora Investigadora

Facultad de Enfermería

Universidad Andres Bello

Santiago, Chile

1
Gabriel Bastias

Profesor Asociado

Facultad de Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Daniela Ahumada

Medico geriatra

COSAM

Municipalidad de Santiago

Santiago, Chile

1
Paola Viviani

Profesor Asistente, categoría Ordinaria

Salud Pública

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Lorena Karzulovic

Profesor Asistente

Pediatría

Pontificia Universidad Católica de Chile

Santiago, Chile