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Lucas Matías Opazo Ríos

Postdoctoral Fellow

Instituto de Investigación Sanitaria Fundación Jiménez Díaz

Madrid, España

Estudio de diversos factores de progresión de las complicaciones macro y microvasculares asociadas a la Diabetes Mellitus, fundamentalmente en contexto de obesidad (nefropatía, retinopatía y cardiomiopatía diabética e hígado graso no alcohólico)

Complicaciones de la Diabetes, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2018
Patología, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2016
Kinesiólogo , UNIVERSIDAD DE CONCEPCION. Chile, 2010

Profesor Auxiliar Part Time

UNIVERSIDAD DE CONCEPCION

Medicina

Concepción, Chile

2011 - 2013
Profesor Auxiliar Part Time

UNIVERSIDAD SANTO TOMAS

de Salud

Valdivia, Chile

2014 - 2014
Profesor Auxiliar Part Time

UNIVERSIDAD SANTO TOMAS

de Salud

Valdivia, Chile

2014 - 2014
Profesor Auxiliar Part Time

UNIVERSIDAD SANTO TOMAS

de Salud

Valdivia, Chile

2014 - 2015
Profesor Auxiliar Part Time

UNIVERSIDAD SAN SEBASTIAN

Medicina

Valdivia, Chile

2015 - 2015
Profesor Ad Honorem Other

UNIVERSIDAD AUSTRAL DE CHILE

Medicina

Valdivia, Chile

2015 - 2016

Academico Investigador Full Time

Universidad de las Américas

Concepción, Chile

2022 - A la fecha


Loss of energy homeostasis contributes to hepatic damage development in sickle cell disease Beltran-Camacho, Lucia; Vallejo-Mudarra, Mercedes; Pozuelo-Sanchez, Isabel; Garcia-Caballero, Cristina; Rojas-Torres, Marta; Lazaro, Iolanda; Sala-Vila, Aleix; Valentin-Aragon, Leo; Caballero-Villarraso, Javier; Opazo-Rios, Lucas; et al. Article ISI MOLECULAR METABOLISM (2026)
SOCS1 Mimetic Peptide Enhances Empagliflozin Improvement on Kidney Damage in the Type 2 Diabetes Mouse Model BTBR ob/ob Aguilar-Cartes, Marcelo; Opazo-Rios, Lucas; Droguett, Alejandra; Mas-Fontao, Sebastian; Moreno, Juan Antonio; Gomez-Guerrero, Carmen; Egido, Jesus; Mezzano, Sergio Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2026)
Nox4 is involved in acute kidney injury associated to intravascular hemolysis García-Caballero, C; Guerrero-Hue M.; Vallejo-Mudarra M.; Antolin, AP; Decouty-Pérez, C; Sánchez-Mendoza, LM; Villalba J.M.; González-Reyes, JA; Opazo-Ríos L; Vázquez-Carballo, C; et al. Article ISI SCOPUS Free Radical Biology and Medicine (2024)
Semaglutide Improves Liver Steatosis and De Novo Lipogenesis Markers in Obese and Type-2-Diabetic Mice with Metabolic-Dysfunction-Associated Steatotic Liver Disease Soto-Catalán, M; Opazo-Ríos L; Quiceno, H; Lazaro, I; Moreno J.A.; Gomez-Guerrero C.; Egido J.; Mas-Fontao S. Article ISI SCOPUS International Journal of Molecular Sciences (2024)
Intravascular hemolysis triggers NAFLD characterized by a deregulation of lipid metabolism and lipophagy blockade Rayego-Mateos S.; Morgado-Pascual, J; García-Caballero, C; Lazaro, I; Sala-Vila A.; Opazo-Ríos L; Mas-Fontao S.; Egido J.; Ruiz-Ortega M.; Moreno J. Article ISI SCOPUS Journal of Pathology (2023)
Kidney microRNA Expression Pattern in Type 2 Diabetic Nephropathy in BTBR Ob/Ob Mice Opazo-RÃƒÂos L.; Tejera-MuÃƒÂ±oz A.; Soto Catalan M.; Marchant V.; Lavoz C.; Mas Fontao S.; Moreno J.A.; Fierro Fernandez M.; Ramos R.; Suarez-Alvarez B.; et al. Article ISI SCOPUS Frontiers in Pharmacology (2022)
Meta-Inflammation and De Novo Lipogenesis Markers Are Involved in Metabolic Associated Fatty Liver Disease Progression in BTBR ob/ob Mice Opazo-RÃƒÂos L.; Soto-CatalÃƒÂ¡n M.; LÃƒÂ¡zaro I.; Sala-Vila A.; JimÃƒÂ©nez-Castilla L.; Orejudo M.; Moreno J.A.; Egido J.; Mas-Fontao S. Article ISI SCOPUS International Journal of Molecular Sciences (2022)
Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury Vázquez-Carballo, C; Herencia C.; Guerrero-Hue M.; García-Caballero, C; Rayego-Mateos S.; Morgado-Pascual J.L.; Opazo-Ríos L; González-Guerrero, C; Vallejo-Mudarra M.; Cortegano I.; et al. Article ISI SCOPUS Journal of Pathology (2022)
The Synthetic Flavonoid Hidrosmin Improves Endothelial Dysfunction and Atherosclerotic Lesions in Diabetic Mice Jimenez-Castilla L.; Opazo-Ríos L; Marin-Royo, G; Orejudo M.; Rodrigues-Diez R.; Ballesteros-Martínez, C; Soto-Catalán, M; Caro-Ordieres, T; Artaiz, I; Suarez-Cortés, T; et al. Article ISI SCOPUS Antioxidants (2022)
Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy Jimenez-Castilla, Luna; Marin-Royo, Gema; Orejudo, Macarena; Opazo-Rios, Lucas; Caro-Ordieres, Teresa; Artaiz, Ines; Suarez-Cortes, Tatiana; Zazpe, Arturo; Hernandez, Gonzalo; Gomez-Guerrero, Carmen; et al. Article ISI ANTIOXIDANTS (2021)
Protective Role of Nrf2 in Renal Disease Palomino-Antolin, Alejandra; Rubio-Navarro, Alfonso; Villalba, Jose Manuel Article ISI ANTIOXIDANTS (2021)
Toll-Like Receptors in Acute Kidney Injury Herencia-Bellido, Carmen; Vallejo-Mudarra, Mercedes; Cortegano, Isabel; Gaspar, Maria Luisa; de Andres, Belen Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob/ob mouse model of type 2 diabetes Droguett, Alejandra Article ISI SCOPUS BMJ Open Diabetes Research and Care (2020)
Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities Article ISI SCOPUS International Journal of Molecular Sciences (2020)
Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy Article ISI SCOPUS International Journal of Molecular Sciences (2020)
Targeting NF-κB by the Cell-Permeable NEMO-Binding Domain Peptide Improves Albuminuria and Renal Lesions in an Experimental Model of Type 2 Diabetic Nephropathy Plaza, Anita; Sánchez Matus, Yenniffer; Bernal, Susana; Lopez-Sanz, Laura; Jimenez-Castilla, Luna; Droguett, Alejandra Article ISI SCOPUS International Journal of Molecular Sciences (2020)
The Coming Age of Flavonoids in the Treatment of Diabetic Complications Caro-Ordieres, Teresa Article ISI JOURNAL OF CLINICAL MEDICINE (2020)
Butyric acid stimulates bovine neutrophil functions and potentiates the effect of platelet activating factor Burgos J.; Opazo L.; Castro L.; Hidalgo M. A.; Figueroa C.D.; Taubert A.; Hermosilla C.; Burgos R.A. Article ISI SCOPUS VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2016)


VEGFR2 KINASE INHIBITION AGGRAVATES FOLIC ACID INDUCED ACUTE RENAL DAMAGE Diez, RR; Opazo L.; Mateos, SR; Navarro, EC; Pascual, JLM; Egido J. Abstract ISI NEPHROLOGY DIALYSIS TRANSPLANTATION (2018)


Creación del Comité de Ejercicio y Enfermedad Renal Crónica de la Sociedad Chilena de Nefrología Paula Moscoso-Aguayo; Aldo Vera-Calzaretta; Lucas Opazo-Ríos; Ailyn Basáez-Fernandez; Lilian Mc Kenzie-Atala Letter ISI SCIELO SCOPUS Revista Medica de Chile (2021)


The Role of miR-802 in Diabetic Kidney Disease: Diagnostic and Therapeutic Insights Tejera-Muñoz, A; Marchant V.; Tejedor-Santamaria L.; Opazo-Ríos L; Lavoz C.; Gimeno-Longas, MJ; Aceña, JL; Ruiz-Ortega M.; Rodrigues-Diez R.R. Review ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2025)
Could IL-17A Be a Novel Therapeutic Target in Diabetic Nephropathy? Opazo-Ríos L; Tejera-Muñoz, A; Navarro-González, JF Review ISI SCOPUS Journal of Clinical Medicine (2020)
Targeting inflammation in diabetic nephropathy: a tale of hope Moreno J.A.; Mas S.; Lorenzo O. Review ISI SCOPUS (2018)