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Manuel Alejandro Maliqueo Yevilao

Profesor asociado

LAB. DE ENDOCRINOLOGIA Y METABOLISMO. FACULTAD DE MEDICINA OCCIDENTE. UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Obesidad, embarazo, función de la placenta, endocrinología reproductiva, metabolismo energético

Tecnólogo Médico, UNIVERSIDAD DE CHILE. Chile, 1997
en Ciencias con mención en Biología de la Reproducción, UNIVERSIDAD DE CHILE. Chile, 2001
Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2009

Profesor asistente Full Time

UNIVERSIDAD DE CHILE

Medicina

SANTIAGO, Chile

2005 - 2018
Profesor Asociado Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2018 - A la fecha
Instructor Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

1999 - 2005

Postdoctorado Full Time

Goteborg Universitet

Gotembuergo, Chile

2011 - 2014
Académico Full Time

Universidad de Chile

Santiago, Chile

1999 - A la fecha
Investigador Visitante Other

Karolisnka Institutet

Estocolomo, Suecia

2015 - 2017

2017 Tesis de Magíster en Ciencias Biológicas Mención Neurociencia, Alumno: Pablo Ruíz Pérez. EFECTO DEL ESTRÉS POR DERROTA SOCIAL SOBRE LAS POBLACIONES NEURONALES DEL CLAUSTRO QUE EXPRESAN LOS GENES MARCADORES NURR1 Y PRSS12, Y SU ASOCIACIÓN CON ALTERACIONES CONDUCTUALES. Directores Dr. Manuel Maliqueo, Dr. Juan Montiel, Dr, Alexis Dagnino-Subiabre (Tutor Académico). Facultad de Ciencias. Universidad de Valparaíso.
2014 Tesis de Doctorado (PhD), Romina Fornes, MSc. ROLE OF ANDROGENS AND OBESITY ON PLACENTAL FUNCTION AND DEVELOPMENT OF POLYCYSTIC OVARY SYNDROME (PCOS). Karolinska. Institutet, Stockholm, Sweden. En Desarrollo. Directores: Elisabet Stener-Victorin, Manuel Maliqueo, Anna Benrick.
2016 Tesis de Titulo Química y Farmacia. Carolina Espina. EXPRESION DEL RECEPTOR DE ANDROGENOS Y ENZIMAS RELACIONADAS A LA SINTESIS DE ANDROGENOS EN LA PLACENTA DE MUJERES OBESAS. Universidad de Valparaíso. Directores: Manuel Maliqueo y Gonzalo Cruz
2016 Tesis de Titulo Química y Farmacia. Isabella Contreras. EFECTOS DE LA OBESIDAD MATERNA EN LA ACCIÓN Y SINTESIS DE PROGESTERONA EN LA PLACENTA HUMANA. Universidad de Valparaíso. Directores: Manuel Maliqueo y Gonzalo Cruz.
2013 Tesis de Magíster en Biomedicina, Pegah Kavyani. ROLE OF ANDROGEN AND ESTROGEN IN PLACENTAL FUNCTION IN PRENATAL ANDROGENIZED RATS. Directores: Elisabet Stener-Victorin y Manuel Maliqueo.University of Skövde, Suecia.
2012 Tesis de Magíster en Biología Molecular. Asif Alvi LETROZOLE INDUCED POLYCYSTIC OVARY SYNDROME IN RATS: EFFECTS OF CYCLIC ESTROGEN TREATMENT. Elisabet Stener-Victorin y Manuel Maliqueo. University of Skövde, Suecia

PREIMIO AL MEJOR TRABAJO PUBLICADO

SOCIEDAD CHILENA DE ENDOCRINOLOGIA Y METABOLISMO

Chile, 2018

Premio al mejor trabajo publicado en 2017


Biotic and abiotic sounds affect calling activity but not plasma testosterone levels in male frogs (Batrachyla taeniata) in the field and in captivity Muñoz, Matías I.; Quispe, Maricel; Maliqueo, Manuel; Penna, Mario Article ISI Hormones and Behavior (2020)
DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children born to women with PCOS Echiburu, Barbara; Crisosto, Nicolas; Flores, Cristian; Arpon, Ana; Recabarren, Sergio E.; Maliqueo, Manuel Article ISI SCOPUS Epigenetics (2020)
Higher luteinizing hormone levels associated with antimullerian hormone in postmenarchal daughters of women with polycystic ovary syndrome Crisosto N.; de Guevara, AL Article ISI SCOPUS FERTILITY AND STERILITY (2019)
Mice exposed to maternal androgen excess and diet-induced obesity have altered phosphorylation of catechol-O-methyltransferase in the placenta and fetal liver Qi X.; Vorontsov E.; Sihlbom C.; NystrÃ¶m J.; CarlstrÃ¶m M. Article ISI SCOPUS INTERNATIONAL JOURNAL OF OBESITY (2019)
Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome Risal, Sanjiv; Pei, Yu; Lu, Haojiang; Manti, Maria; Pui, Han-Pin; Zhao, Zhiyi; Massart, Julie; Ohlsson, Claes; Lindgren, Eva; Crisosto, Nicolas; et al. Article ISI SCOPUS NATURE MEDICINE (2019)
Cell and molecular mechanisms behind diet-induced hypothalamic inflammation and obesity Ávalos, Yenniffer; Kerr, Bredford; Maliqueo, Manuel; Dorfman, Mauricio Article ISI SCOPUS JOURNAL OF NEUROENDOCRINOLOGY (2018)
Enlarged adipocytes in subcutaneous adipose tissue associated to hyperandrogenism and visceral adipose tissue volume in women with polycystic ovary syndrome Article ISI SCOPUS STEROIDS (2018)
Maternal androgen excess and obesity induce sexually dimorphic anxiety-like behavior in the offspring Manti, M; Fornes R.; Qi, XJ; Folmerz, E; Hirschberg, AL; Barbosa, TD; Maliqueo M.; Benrick, A Article ISI SCOPUS FASEB JOURNAL (2018)
Pregnancy outcomes in women with polycystic ovary syndrome in two Latin American populations Fux-Otta, Carolina; Rosato, Otilio; Iraci, Gabriel S.; Fiol de Cuneo, Marta; Szafryk de Mereshian, Paula Article ISI SCOPUS JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2018)
Prenatal metformin treatment improves ovarian function in offspring of obese rats Article ISI SCOPUS Journal of Endocrinology (2018)
Hypothalamic transcriptional expression of the kis-speptin system and sex steroid receptors differs among polycystic ovary syndrome rat models with different endocrine phenotypes Marcondes, Rodrigo Rodrigues; Carvalho, Katia Candido; Giannocco, Gisele; Duarte, Daniele Coelho; Soares-Junior, Jose Maria; Cotrim Guerreiro da Silva, Ismael Dale; Maliqueo, Manuel; Baracat, Edmund Chada; Rosa Maciel, Gustavo Arantes Article ISI Clinics (2017)
Reproductive and metabolic features during puberty in sons of women with polycystic ovary syndrome Luchsinger, M Article ISI SCOPUS Endocrine Connections (2017)
The effect of androgen excess on maternal metabolism, placental function and fetal growth in obese dams Hadi, L; Jimenez-Andrade, JM; Ebefors, K Article ISI SCOPUS Scientific Reports (2017)
Relationship Between Anti-Mullerian Hormone (AMH) and Insulin Levels During Different Tanner Stages in Daughters of Women With Polycystic Ovary Syndrome Sir Petermann T; Guevara A.L.D.; Codner E.; Preisler J.; Crisosto N.; Echiburú, B; Maliqueo M.; Sanchez F.; Perez-Bravo F.; Cassorla F. Article ISI SCOPUS Reproductive Sciences (2012)
Expression of Androgen and FSH Receptors and AMH in Testis of Lambs Prenatally Exposed to an Excess of Testosterone. Rojas-Garcia, PP; Palma S.; Maliqueo M.; Tovar, H; Rey R.; Sir Petermann T Article ENDOCRINE REVIEWS (2010)


PERINATAL NUTRITION AND METABOLIC DISEASE Cruz, Gonzalo; Fernandois, Daniela; , GONZALO JORQUERA OLAVE; Llanos, Paola; Maliqueo, Manuel; Palma, Ximena; Manlio Vinciguerra; Paul Cordero Sanchez BookSection (2020)
ACUPUNCTURE Stener-Victorin, Elisabet; Benrick, Anna; Fornes, Romina; Maliqueo, Manuel; Palomba, Estefano BookSection (2018)
LA PROGRAMACIÓN FETAL Y LA SALUD DEL ADULTO Maliqueo, Manuel; Cordero, Miguel; Molina, Helia BookSection (2016)


Alterations in spermatozoa DNA methylation in sons of women with polycystic ovary syndrome (PCOS): a male intergenerational inheritance approach Echiburu, Barbara; Maliqueo, Manuel; Montiel, Juan Fidel; Crisosto, Nicolas Proyecto (2020)
Association between maternal metabolic disturbances during the first pregnancy and breast density Kusanovic, J; Jacard, M Proyecto (2019)
Effect Of Intrauterine Environment On Epigenetic Changes Of Selected Genes Linked With Metabolic And Reproductive Dysfunction In The Offspring Of Hyperandrogenic Mothers: A Translational Approach Maliqueo, Manuel; Sandoval, Daniel; Recabarren, Sergio Proyecto (2018)
Maternal obesity influences placental fatty acid transport. Are there an impact on fatty acid metabolism in the fetal liver? Maliqueo, Manuel; Espinosa, Berta Alejandra; Crisosoto, Nicolás; Montiel, Juan Proyecto (2018)
Maternal obesity influences fetal hepatic lipid accumulation. Role of placental lipid transport Maliqueo, Manuel Proyecto (2017)
Effects of maternal obesity on steroid levels during pregnancy. A possible relationship between adipose tissue and inflammatory factors on placental steroidogenesis Maliqueo, Manuel Proyecto (2013)
Reproductive and metabolic features during the menopausal transition and the early postmenopausal period in women with polycystic ovary syndrome (PCOS): deepning into the pathophysiology of PCOS Maliqueo, Manuel Proyecto (2011)