Man

Nicolás Pablo Cifuentes Muñoz

DIRECTOR

VERTEBRAL LTDA

Santiago, Chile

Líneas de Investigación


REPLICACIÓN Y ENSAMBLAJE DE VIRUS RESPIRATORIOS; VIROLOGÍA CELULAR Y MOLECULAR; METAPNEUMOVIRUS HUMANO, VIRUS RESPIRATORIO SINCICIAL; COINFECCIONES VIRALES; BIOLOGÍA CELULAR; BIOLOGIA MOLECULAR

Educación

  •  Biotecnología, UNIVERSIDAD ANDRES BELLO. Chile, 2011
  •  BIOQUIMICO, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2005
  •  BIOQUIMICA, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2004

Experiencia Académica

  •   INVESTIGADOR DOCENTE Full Time

    UNIVERSIDAD AUTÓNOMA DE CHILE

    CIENCIAS DE LA SALUD

    SANTIAGO, Chile

    2019 - 2021

  •   PROFESOR ASOCIADO Part Time

    UNIVERSIDAD DE LAS AMERICAS

    SANTIAGO, Chile

    2008 - 2014

  •   PROFESOR ADJUNTO Part Time

    UNIVERSIDAD ANDRES BELLO

    CIENCIAS DE LA VIDA

    SANTIAGO, Chile

    2008 - 2013

  •   PROFESOR AUXILIAR Full Time

    UNIVERSIDAD AUSTRAL DE CHILE

    CIENCIAS

    VALDIVIA, Chile

    2021 - 2021

Experiencia Profesional

  •   POSTDOCTORAL SCHOLAR Full Time

    UNIVERSITY OF KENTUCKY

    LEXINGTON, Estados Unidos

    2014 - 2019

  •   INVESTIGADOR POSTDOCTORAL Full Time

    FUNDACION CIENCIA & VIDA

    SANTIAGO, Chile

    2011 - 2014

  •   HEAD OF RESEARCH PROJECTS & PHAGES Full Time

    PHAGELAB

    SANTIAGO, Chile

    2021 - 2024

  •   DIRECTOR DE PRODUCCIÓNY PRODUCTO Full Time

    VERTEBRAL LTDA

    SANTIAGO, Chile

    2025 - A la fecha

Formación de Capital Humano


DIRECTOR DE TESIS
2019 - 2020 Conny Ossandón Aguirre - Biotecnología, Universidad de Antofagasta

EXPERIENCIA COMO MENTOR
Estudiantes de doctorado
2017 - 2019 Rachel Thompson – University of Kentucky
2018 Anastasia Lyon – University of Kentucky
2016 - 2017 Jean Branttie – University of Kentucky
2016 Kerri Beth Slaughter – University of Kentucky
2016 Beth Oates – University of Kentucky
2016 Zoe Simmons – University of Kentucky
2015 - 2016 Tyler Kinder – University of Kentucky
2015 Kathryn Lethbridge – University of Kentucky

Estudiantes de pregrado
2017 Santiago Restrepo – University of Kentucky
2016 - 2017 Connor van Meter – University of Kentucky
2015 - 2017 Aqeel Jawahir – University of Kentucky
2012 - 2013 Luis Osorio – Universidad de Antofagasta


Difusión y Transferencia


2018 Científico invitado
Programa de difusión científica “Hablando con científicos”
URL: http://cienciaes.com/entrevistas/2018/04/16/estrategias-virales/

2010 - 2014 Instructor
Encuentro de jóvenes con la ciencia y tecnología ChileVa!
Consejo Nacional de Innovación Para la Competitividad, Chile

2008 - 2013 Instructor
Programa “1000 científicos 1000 aulas”
Explora Conicyt, Chile


Premios y Distinciones

  •   Mejor presentación categoría póster

    11th International Respiratory Syncytial Virus symposium

    Estados Unidos, 2018

    Premio mejor presentación categoría póster

  •   2do lugar competencia anual de postdoctorados

    “Dean’s Distinguished Lecture”. University of Kentucky College of Medicine.

    Chile, 2017

    2do lugar competencia anual de postdoctorados

  •   Distinción presidencial

    Presidencia de la República

    Chile, 2021

    Distinción por el apoyo experto durante la pandemia de COVID-19


 

Article (16)

Research Note: Reduction of Salmonella load in Brazilian commercial chicken farms using INSPEKTOR®: a bacteriophage-based product

Pino, Michael; Mujica, Karen; Mora-Uribe, Paola; Garcias-Papayani, Hector; Paillavil, Braulio; Avendano, Camilo; Flores-Crisosto, Diego; Norambuena, Rodrigo; Rojas-Martinez, Victoria; Aguilera, Matias; et al.

Article ISI
POULTRY SCIENCE  (2025)

Development and characterization of a bacteriophage cocktail with high lytic efficacy against field-isolated<i> Salmonella</i><i> enterica</i>

Cifuentes, Onix; Zamudio, Maria Sofia; Lara, Pabla; Sabag, Andrea; Tichy, Daniel; Leon, Luis; Pino, Michael; Rojas, Felipe; Pieringer, Christian; Muster, Cecilia; et al.

Article ISI
POULTRY SCIENCE  (2023)

Imaging analysis reveals budding of filamentous human metapneumovirus and direct transfer of inclusion bodies through intercellular extensions

El Najjar, Farah; Castillo, Santiago Restrepo; Moncman, Carole L.; Wu, Cheng-Yu; Isla, Eduardo; Ortega, A. Catalina Velez; Frolenkov, Gregory I.

Article ISI
mBio  (2023)

Factors Influencing the Acceptance of COVID-19 Vaccines in a Country with a High Vaccination Rate

Toro-Ascuy, Daniela

Article ISI
VACCINES  (2022)

Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies

Boggs, Kerri Beth; Edmonds, Kearstin; Ossandon, Conny; Roe, McKenna; Wu, Chao; Creamer, Trevor P.; Leung, Daisy W.

Article ISI
mBio  (2022)

Overnutrition, Nasopharyngeal Pathogenic Bacteria and Proinflammatory Cytokines in Infants with Viral Lower Respiratory Tract Infections

Tapia, Cecilia; Toro-Ascuy, Daniela

Article ISI
International #Journal of Environmental Research and Public Health  (2022)

To assemble or not to assemble: The changing rules of pneumovirus transmission.

Dutch, R.

Article
VIRUS RESEARCH  (2019)

Direct cell-to-cell transmission of respiratory viruses: The fast lanes

Cattaneo, Roberto

Article ISI
PLOS PATHOGENS  (2018)

Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription

Branttie, Jean; Slaughter, Kerri Beth; Dutch, Rebecca Ellis

Article ISI
JOURNAL OF VIROLOGY  (2017)

Mutations in the transmembrane domain and cytoplasmic tail of Hendra virus fusion protein disrupt virus-like particle assembly.

Cifuentes-Muñoz, Nicolás; Sun, Weina; Ray, Greeshma; Schmitt, Phuong Tieu; Webb, Stacy; Gibson, Kathleen; Dutch, Rebecca Ellis; Schmitt, Anthony P

Article
Journal of virology  (2017)

Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread.

El Najjar, Farah; Cifuentes-Muñoz, Nicolás; Chen, Jing; Zhu, Haining; Buchholz, Ursula J; Moncman, Carole L; Dutch, Rebecca Ellis

Article
PLoS pathogens  (2016)

Hantavirus Gn and Gc envelope glycoproteins=> key structural units for virus cell entry and virus assembly.

Cifuentes-Muñoz, Nicolás; Salazar-Quiroz, Natalia; Tischler, Nicole D

Article
Viruses  (2014)

Hantavirus Gn and Gc glycoproteins self-assemble into virus-like particles.

Acuña, Rodrigo; Cifuentes-Muñoz, Nicolás; Márquez, Chantal L; Bulling, Manuela; Klingström, Jonas; Mancini, Roberta; Lozach, Pierre-Yves; Tischler, Nicole D

Article
Journal of virology  (2014)

First detection and complete genome sequence of Deformed wing virus in Chilean honeybees.

Barriga GP, Cifuentes-Muñoz N; Rivera PA, Gutierrez M; Shmaryahu A, Valenzuela PD

Article
Virus Genes  (2012)

Aromatic and polar residues spanning the candidate fusion peptide of Andes virus are essential for membrane fusion and infection

Nicolás Cifuentes-Muñoz, Gonzalo P. Barriga

Article
Journal of general virology  (2011)

Development of a lentiviral vector system to study the role of the Andes virus glycoproteins

Nicolás Cifuentes-Muñoz, Jean-Luc Darlix and Nicole D. Tischler

Article
Virus research  (2010)

BookWhole (1)

Human papillomavirus and non-coding RNAs: From basics to diagnostic

Villota, C; Burzio L.O.

BookWhole SCOPUS
Materials Science and Technology Conference and Exhibition 2014, MS and T 2014  (2013)

Proyecto (4)

Characterizing human metapneumovirus (HMPV) nucleocapsids and inclusion body dynamics: Role of the actin cytoskeleton and the viral phosphoprotein



Proyecto
 (2018)

INTERFERENCIA DE NCMTRNAS DE ORIGEN CANINO COMO UNA NOVEDOSA Y SELECTIVA TERAPIA ANTITUMORAL.

FONDECYT (3140006)

Proyecto
2013-2016
Inv. Responsable

Desarrollo de una nueva terapia selectiva contra infecciones causadas por virus Influenza A

PAI (78110105)

Proyecto
2011-2013
Inv. Responsable

Implementation and standardization of methods for the analysis of fusogenic properties of Andes hantavirus Gc protein

Universidad Andrés Bello (UNAB DI-05-08/I)

Proyecto
2008-2009
Inv. Responsable

Review (2)

Viral cell-to-cell spread: Conventional and non-conventional ways

Kielian, M; Mettenleiter, TC; Roossinck, MJ

Review ISI
VIRUS ASSEMBLY AND EXIT PATHWAYS  (2020)

To assemble or not to assemble: The changing rules of pneumovirus transmission

Cifuentes-Muñoz N.; Ellis Dutch R.

Review ISI SCOPUS
VIRUS RESEARCH  (2019)

1
Claudio Villota

Profesor/investigador Asociado

Facultad de Salud

Universidad Bernardo O'Higgins

Santiago, Chile

1
Luis Burzio

Scientific Director

Andes Biotechnologies

FUNDACION CIENCIA PARA LA VIDA

Santiago, Chile

13
Nicolás Cifuentes

DIRECTOR

PRODUCTO Y PRODUCCIÓN

VERTEBRAL LTDA

Santiago, Chile

1
Francisco Zorondo

Profesor Asociado

Departamento de Gestión Agraria

Universidad de Santiago de Chile

Santiago, Chile

2
Daniela Toro

Profesor Asistente

Facultad de ciencias

Universidad de Chile

Santiago, Chile

1
Christian Pieringer

Manager of Artificial Intelligence and Data Science

Artificial Intelligence & Data Science

PhageLab Spa

San Joaquín, Chile

1
Soledad Ulloa

Jefa de departamento

Diagnóstico Molecular

PhageLab Chile

Santiago, Chile