Protein Chemistry; Molecular Biology; General Microbiology; Actinobacteria; Streptomyces; Marine Microbiology; Secondary Metabolites; Bioactive Compounds; Phylogenetic Biodiversity

Student and postdoctoral training

Undergraduate thesis supervisor (9 finished):
1. Maria José Vargas, Biochemist, Universidad de Santiago de Chile. 2012.
2. Fernanda Claverías, Environmental Civil Engineering, UTFSM. 2014.
3. Valentina González, Environmental Civil Engineering, UTFSM. 2015
4. Andrés Cumsille, Environmental Civil Engineering, UTFSM. 2015
5. Gastón Vergara, Environmental Civil Engineering, UTFSM. 2016
6. Claudia Rojas Fuentes, Environmental Civil Engineering, UTFSM. 2016
7. Vania Molina Cádiz, Environmental Civil Engineering, UTFSM. 2019
8. Neri Salem Vargas Bermudez, Environmental Civil Engineering, UTFSM. 2022.
9. Raúl Cruz, Civil Informatics Engineering, UTFSM. 2024.
** Ian Catalán, Biochemist, PUCV (Ongoing).

Master thesis supervisor (In Chile):
Jeanette Ehlersson, Pharmacist, University of Gothenburg, Sweden. (2011).

PhD thesis supervisor (9 finished):
1. Agustina Undabarrena Canusso, PhD in Sciences, mention in Microbiology, joint program Universidad de Chile y USACH. 2017 (Co-Supervisor).
Awarded by the Chilean Microbiology Society as the best PhD thesis in Microbiology 2017.
2. Valentina Alejandra González Fuenzalida, PhD in Biotechnology, joint program UTFSM-PUCV. 2021.
3. Fernanda Paz Claverías Ramos, PhD in Microbiology, UACh. 2023.
Awarded by the Universidad Austral de Chile as the best PhD graduate in science, class of 2023.
4. Néstor Serna Cardona, PhD in Biotechnology, joint program UTFSM-PUCV. 2023.
5. Leonardo Zamora Leiva, PhD in Biotechnology, joint program UTFSM-PUCV. 2023.
6. Andrés Cumsille Montesinos, PhD in Biotechnology, joint program UTFSM-PUCV. 2023.
** Laura Muñoz, PhD in Biotechnology, joint program UTFSM-PUCV (Ongoing).
** Alison Acosta, PhD in Biotechnology, joint program UTFSM-PUCV (Ongoing).
** Eduardo Sánchez Carvajal, PhD in Biotechnology, joint program UTFSM-PUCV (Ongoing).

Advisor of 3 PosDocs:
1. Agustina Undabarrena. 2018 - 2021.
2. Valentina González. 2022 - 2023.
3. Fernanda Claverías. 2024 - 2026.

Congress presentations:

Participation as author in 126 national and international scientific events (shown for the last 5 years)

- 2024 -

4th Synthetic Biology of Natural Products Conference – Cancun – Mexico
- Claverías F, Serna N, González V, Zamora L, Acosta A, Sánchez E, Cumsille A, Undabarrena A, Cámara B. Genomic-metabolomic connections: A promising pathway for finding antibiotic chemical pathway. Poster and Talk
- Eduardo Sánchez Carvajal, Neri Vargas Bermúdez, Andrés Cumsille, Beatriz Cámara. Phylogenomic and biosynthetic novelty of four marine Streptomyces from Southern Chile: prioritizing for bioactive compounds. Poster

Scientific Symposium “From the Neckar Valley to the Cordillera de Los Andes: Breaking borders with Molecular Systems Engineering” – University of Heidelberg / Heidelberg Center for Latin America - Santiago - Chile
- Claverías F & Cámara B. BGC similarity networks in S. alimapuensis and the family Nocardiopsaceae to assess novelty of potential RiPPs
- Cámara B & Seeger M. “From the Natural Microbial Heritage of Chile to Bioactive Compounds, Biocatalysts, and Biocontrol”. Talk

- 2023 -

LXVI Reunión Anual Sociedad de Biología – Valparaíso - Chile
- Cámara B. Actinobacterias marinas del Pacífico Sur: un mar de posibilidades. Talk
- Sánchez-Carvajal E, Vargas Bermúdez N, Cumsille A & Cámara B. Divergencia filogenómica ligada a la novedad biosintética de péptidos no ribosómicos en cuatro Streptomyces marinas de la Región de Aysén, Chile
- Vargas Bermúdez N, Sánchez-Carvajal E, Zamora Leiva L, Serna Cardona N, Cumsille A & Cámara B. Estudios metabologenómicos de actividad antimicrobiana contra Mycobacterium smegmatis de Salinibacterium sp. AL4.1, un actinomiceto aislado de
sedimentos marinos de la Región de Aysén, Chile
- Zamora Leiva L, Serna Cardona N, Sánchez-Carvajal E, Claverías F & Cámara B. NetworkFlow: Una herramienta bioinformática automatizada para la búsqueda de nuevos Agrupamiento de Genes Biosintéticos
- Serna-Cardona N, Cumsille A, Zamora-Leiva L, González V, Vergara M, Altamirano C, Tietze A, Tessini C, Reyes F, Olano C, Salas JA, Undabarrena A & Cámara B. Develando el potencial de las Streptomyces marinas: descubriendo nuevos péptidos
antibiótico a través de Molecular Networking e ingeniería genética
- Claverías F, Cumsille A, Sánchez-Carvajal E & Cámara B. Redes de similitudes de BGCs en Spiractinospora alimapuensis (Chile) y la familia Nocardiopsaceae para evaluar novedad de los potenciales RiPPs
- González V, Serna-Cardona N, Beys-da-Silva, WO, Karlsson R, Alarcon L, Seeger M & Cámara B. Análisis proteómico de una Streptomyces marina: Dilucidando el mecanismo de degradación de la queratina de las plumas
- Acosta A, Zamora Leiva L, Serna Cardona N, Sánchez-Carvajal E, Salvà-Serra F, Moore ERB & Cámara B. Evaluación del efecto antibiopelícula de metabolitos de Rhodococcus sp. contra Pseudomonas aeruginosa

XLV Congreso Chileno de Microbiología SOMICH – Pucón – Chile
- Cámara B. Bioprospection of marine actinomycetes: a sea of possibilities. Invited talk in Marine Microbiology symposium.
-Claverías F, Cumsille A & Cámara B. BGC similarity networks in Spiractinospora alimapuensis and the family Noocardiopsaceae to assess novelty in potential RiPPs. Awarded as best oral communication

Iimena Symposium: Integrating Informatics and Metabolomics Engineering for the Discovery of Novel Antibiotics – Copenhagen – Denmark
- Cámara B. Marine actinomycetes from the South Pacific: a sea of possibilities. Invited Talk, 25th September

XVII MaNaPro International Symposium on Marine Natural Products & XIII ECMNP European Conference on Marine Natural Products – Granada – Spain
- Serna-Cardona N, Cumsille A, Huerta M, Zamora-Leiva L, Undabarrena A, Tessini C, Angulo A & Cámara B. Genomic-metabolomic connections: a promising pathway for finding antibiotic chemical novelty. Talk, 3-8th September
- Serna-Cardona N, Cumsille A, Zamora-Leiva L, González V, Vergara M, Altamirano C, Tietze A, Tessini C, Reyes F, Olano C, Salas JA, Undabarrena A & Cámara B. Unlocking the potential of marine Streptomyces: discovery of novel bioactive peptides
through metabolomic profiling and genetic engineering, 3-8th September

3rd ISME Latin America ISME-LA – Buenos Aires – Argentina
- Sánchez Carvajal E, Vargas Bermúdez N, Zamora-Leiva L, Cumsille A, Serna-Cardona N, Tessini C, Cámara B. Isolation of actinomycetes from marine sediments of the Aysén Region, Chile, and genomic and metabolomic studies of antimicrobial activity
of the strain Salinibacterium sp. A-L4.1.

BIOTEC 2023. XVIII Congreso de la Sociedad Española de Biotecnología – Madrid – Spain
- González V, Serna-Cardona N, Beys-da-Silva, WO, Karlsson R, Alarcon L, Seeger M & Cámara B. Proteomic analysis of keratinolytic Streptomyces sp. G11C identifies relevant enzymes in the mechanism of feather keratin degradation.
Awarded as best poster presentation

15th International Conference on Culture Collections ICCC, University of Minho, Campus Gualtar – Braga – Portugal
- Claverías F, Zamora-Leiv L, González V, Cumsille A & Cámara B. Taxonomically unique Actinomycetes isolated from Chilean marine environments: Corynebacterium alimapuense sp. nov. and Spiractinospora alimapuensis gen. nov., sp. nov.

Workshop Meta-Omics – Zurich - Switzerland
- Cumsille A, Serna-Cardona N, Huerta M, Zamora-Leiva L, Sánchez-Carvajal E, Claverías F, Undabarrena A, Tessini C, Angulo A & Cámara B. Exploring Antibiotic Chemical Novelty in marine Actinomycetota, through Genomic-Metabolomic Connections.

- 2022 -

XLIV Congreso Chileno de Microbiología SOMICH – La Serena – Chile
- Sánchez-Carvajal E, Zamora-Leiva L, Serna-Cardona N, Cámara B. Perspectiva genómica sobre el potencial biosintético de Streptomyces sp. VB1, un actinomiceto derivado de sedimentos marinos de la Bahía de Valparaíso
- Vargas Bermúdez N, Cumsille A, Cámara B. Aislamiento y caracterización de Actinobacterias marinas de la costa de la Región de Aysén y evaluación de su potencial actividad antimicrobiana
- Valentina Alejandra González Fuenzalida, Ricardo Valencia, Agustina Undabarrena, Leonardo Zamora Leiva, Walter O. Beys-da-Silva, Beatriz Cámara. Estudio proteómico valida el análisis bioinformático integrativo que detectó queratinasas en
Streptomyces marinas.
Awarded as best oral communication-
- Sepúlveda-Mardonés M., Báez-Matus X., Serna-Cardona N., Bravo-Cortés G., Vega-Celedón P., Cámara B., Díaz-Barrera A., Seeger M. Janthinobacterium sp. BmR6b co-produces violacein with antibacterial and antioxidant activities during a
polyhydroxybutyrate production process.

19th International Symposium on the Biology of Actinomycetes – Toronto - Canada
- Cumsille A, Serna-Cardona N, Undabarrena A, Tietze D, Tietze A, Reyes F, Cámara B. Bioprospecting antimicrobial compounds from the South Pacific. Insights into the chemical and biosynthetic space of Streptomyces sp. VS4-2.
- Serna-Cardona N, Zamora-Leiva L, Cumsille A, Claverías F, González V, Sánchez E, Acosta A, Undabarrena A, Cámara B. Exploring the chemical and genetic space of Actinomycetes from the South Pacific.

Congreso EuroBiofilms 2022, Mallorca - Spain
- Acosta A., González V., Zamora L., Cumsille A., Salvà-Serra F, Cámara B. A marine Rhodococcus with anti-biofilm activity against Pseudomonas aeruginosa.

- 2021 -

LXIV Reunión Anual Sociedad de Biología
- Undabarrena A, Serna-Cardona N, Cumsille A, Zamora-Leiva L, González V, Claverías F, Seeger M & Cámara B. Desde el fondo del mar: Avances en la búsqueda de compuestos bioactivos en Actinobacterias de las costas chilenas. Talk.
Awarded the Dr. Humberto Maturana prize, in the Young Researchers Symposium

Congreso Digital Chileno de Microbiología SOMICH
- Cumsille A, González V, Undabarrena A, Claverías F & Cámara B. Comparative genomics in the Genus Brevibacterium
- Vargas N, Cumsille A & Cámara B. Isolation and characterization of marine from Aysén
- Claverías FP, Durán RE, Cumsille A, Serna-Cardona N, Zamora Leiva L, Riesco R, Seeger M, Trujillo ME & Cámara B. Taxonomy and ecological adaptation of strain VN6-2, a novel genus of the family Nocardiopsaceae isolated from marine sediment of
Valparaíso Bay, Chile
- Zamora Leiva L, Undabarrena A, Valencia R & Cámara B. Bioinformatic analysis of Streptomyces strains isolated from the Pacific Ocean, for the search of novel biosynthetic gene clusters. Talk

Leibniz-Institute DSMZ – German Collection of Microorganisms and Cell Cultures, Braunschweig & Interfaculty Institute of Microbiology and Infection Medicine, Eberhard Karls University of Tübingen, Tübingen – VAAM Workshop Biology of Bacteria Producing Natural Products. Online Poster

VAAM Workshop 2021 – Biology of Bacteria Producing Natural Products. Online
- Undabarrena A., Serna N., Zamora-Leiva L., Cumsille A., González V., Valencia R., Ugalde J., Reyes F., Salas J. & Cámara B. From the bottom of the sea: insights into a new member of the tetrahydroisoquinoline family antibiotics. Talk

XXV Congreso Latinoamericano de Microbiología – ALAM 2021, 25-28 August 2021, online
- Claverías FP, Durán RE, Seeger M, Cámara B. Comparative genomics and pangenomics of the Nocardiopsaceae family reveals insights into marine gene adaptations of strain VN6-2, a novel marine Actinobacteria isolated from Valparaíso Bay, Chile

ISMELAT 2021, 27-30 July 2021, online
- Cumsille A, González V, Undabarrena A, Claverías F, Cámara B. Comparative genomics in the Genus Brevibacterium
- Zamora-Leiva L, Undabarrena A, Valencia R, Cámara B. Integration of bioinformatic tools in an automatized workflow for the search of novel biosynthetic gene clusters.
Awarded as best poster presentation

XII European Conference on Marine Natural Products. XII ECMNP 2021 - Galway – Ireland
- Serna N, Cumsille A, Undabarrena A, Cámara B. Exploring chemical diversity of marine streptomycetes from the Pacific Ocean through molecular networking.

World Microbe Forum, ASM and FEMS collaboration, 20-24 June 2021, online
- Cumsille A, Undabarrena A, Serna-Cardona N, Reyes F, Cámara B. Similarity networks to bioprospect antimicrobial compounds from marine actinobacteria.
- Claverías FP, Durán RE, Seeger M, Cámara B. Comparative genomics of the Nocardiopsaceae family reveals insights into marine gene adaptations of strain VN6-2, a novel marine Actinobacteria isolated from Valparaíso Bay, Chile

- 2020 -

Congreso Digital Chileno de Microbiología SOMICH
- Cumsille A, Woolery M, Reyes F, Cámara B. Similarity networks to bioprospect antimicrobial compounds from marine actinobacteria
- Undabarrena A, Serna N, González V, Olano C, Salas JA, Cámara B. Genetic engineering in marine Streptomyces: insights into the biosynthesis of novel compounds

LXIII Reunión Anual Sociedad de Biología
- Undabarrena A, Valencia R, Cumsille A, Zamora-Leiva L, Castro-Nallar E, Barona-Gomez F, Cámara B. La genómica evolutiva del género Rhodococcus revela rasgos biosintéticos de productos naturales ancestrales dependientes de la filogenómica. Talk
- Cumsille A, Woolery M, Reyes F, Cámara B. Redes de similitud para la Bioprospección de antimicrobianos naturales producidos por actinobacterias marinas. Awarded as best poster presentation
- González V, Vargas-Straube MJ, Beys-da-Silva W, Santi L, Beltrametti F, Cámara B. Bioprospection of marine-derived Actinobacteria from the Chilean coast and new insight in the mechanism of keratin degradation in Streptomyces sp. G11C

Segunda Jornada de Biocatálisis. JBiocat 2019 – Santiago – Chile
- González V, Valencia P, Cámara B. Caracterización del extracto enzimático de Streptomyces sp. G11C utilizado en la hidrólisis de queratina de plumas

Charlas / Talks

“El espacio químico de las Actinomicetes marinas nos brinda un mar de posibilidades”
Talk – Department of Chemistry, UTFSM.
22nd October 2020

“A genomics and metabolomics guided bioprospection of marine actinomycetes of the South Pacific”
Talk – ActinoBase e-Seminar (Youtube Channel).
6th August 2020

“Actinobacteria from the South Pacific: A bioprospection for Natural Bioproducts”
Talk – Center for Biotechnology, Universidade Federal do Rio de Janeiro, Brazil.
16th January 2020

“Marine actinobacteria from Chilean coasts: a prospective source for the discovery of keratinases.”
Talk – XLI Congreso Chileno de Microbiología SOMICH, Puerto Varas, Chile.
8th November 2019

“Actinobacteria from the South Pacific – Chemical diversity of specialized metabolites.”
Talk – XV Symposium on Bacterial Genetics and Ecology BAGECO – Lisbon – Portugal.
30th May 2019

“Actinobacteria from the South Pacific: A bioprospection for Natural Bioproducts”
Talk – Universidade Federal do Rio de Janeiro, Brazil.
22nd January 2019

“Chilean marine actinobacterial culture collection: an important resource for bioprospection”
Talk - XXIV Congreso Latinoamericana de Microbiología ALAM 2018 - XL Congreso Chileno de Microbiología SOMICH, Santiago, Chile.
13th – 16th November 2018

“Bioprospecting marine actinobacteria from the south Pacific: from isolation to genome mining and metabolomics”
Talk – II Simposio Biotecnología Microbiana y Bioingeniería. Universidad Católica del Norte, Antofagasta, Chile
30th-31st August 2018

“Bioprospecting bioactive compounds: targeting marine actinobacteria from the Northern Chilean Patagonia”
Talk – Humboldt University, Berlin, Germany
21st August 2018

“Bioprospección de actinobacterias marinas: búsqueda de enzimas implicadas en el mecanismo de la queratina.”
Talk – University of Oviedo, Spain
19 July 2018

“Bioprospecting bioactive compounds: targeting marine actinobacteria from the Northern Chilean Patagonia”
Talk - Imperial College London, London, UK
10th July 2018

“Un mar de posibilidades”
TEDx talk Universidad Diego Portales, Santiago, Chile
4th October 2017

“Bioprospecting marine actinobacteria from the south Pacific: from isolation to genome mining and metabolomics”
Talk – Simposio Biotecnología Microbiana y Bioingeniería. Universidad Andrés Bello, Santiago, Chile
24-25th August 2017

“Actinobacteria from the South Pacific: A bioprospection for Natural Bioproducts.”
Talk – CCUG, University of Gothenburg, Gothenburg, Sweden.
2nd June 2016

“Actinobacteria from the South Pacific: A bioprospection for Natural Bioproducts.”
Talk – Universidad de Oviedo, Oviedo, Spain.
25th May 2016

“Actinobacteria from Marine Sediments in the South Pacific: a Potential Bioprospection for Novel Bioactive Natural Products.”
Talk – Imperial College London, London, UK
16th August 2013

“In search of novel Antibiotics acting on Bacterial RNA polymerases”
Coloquio Microbiología 2011 – Universidad Técnica Federico Santa María, Valparaíso, Chile
19th May 2011

“Structure-function analysis of a potent bacterial RNA polymerase inhibitor”
Annual Research Open Day – Centre for Structural Biology – Imperial College London, UK
We were 6 invited speakers, including Nobel Prize Winner of Chemistry 2009, Dr Venki Ramakrishnan
24th September 2010

“Functional and structural characterisation of T7 Gp2: a potent inhibitor of the Escherichia coli RNA polymerase”
21st Annual RNA Polymerase Workshop
University of Bristol, Bristol, UK
23rd – 24th March 2009