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ERICK MARCELO RIQUELME SANCHEZ

ASSISTANT PROFESSOR

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

My research has focused on studying the interaction of the tumor with the immune system, specifically the factors that regulate the tumor microenvironment and in this context the role played by the microbiota in regulating the tumor microenvironment.

BIOLOGICAL SCIENCE, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2010
BIOLOGICAL SCIENCE, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
Tecnologo Medico, UNIVERSIDAD DE CHILE. Chile, 2001

POST DOCTORAL FELLOW Full Time

UT MD ANDERSON CANCER CENTER

Houston, Estados Unidos

2010 - 2019


Bacteria and fungi: The counteracting modulators of immune responses to radiation therapy in cancer Riquelme, Erick Article ISI CANCER CELL (2021)
Early Detection of Pancreatic Intraepithelial Neoplasias (PanINs) in Transgenic Mouse Model by Hyperpolarized C-13 Metabolic Magnetic Resonance Spectroscopy Dutta, Prasanta; Pando, Susana Castro; Mascaro, Marilina; Riquelme, Erick; Zacharias, Niki M.; Gammon, Seth T.; Pagel, Mark D.; Sen, Subrata; Maitra, Anirban; Shams, Shayan; et al. Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer Chandra, Vidhi; Riquelme Sanchez, Erick; Quesada, Pompeyo R.; Rakoski, Amanda; Arora, Nivedita; Baydogan, Seyda; Burks, Jared; Hussain, Perwez; Wang, Huamin; Maitra, Anirban; et al. Article ISI JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes Montiel M.; Zoltan M.; Quesada P.; Sahin I.; Chandra V.; San Lucas A.; Scheet P.; Hanash S.M.; Burks J.K.; Do K.-A.; et al. Article ISI SCOPUS CELL (2019)
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients Gopalakrishnan, V.; Spencer, C. N.; Nezi, L.; Reuben, A.; Andrews, M. C.; Karpinets, T. V.; Prieto, P. A.; Wei, S. C.; Cogdill, A. P.; Hudgens, C. W.; et al. Article SCIENCE (2018)
Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells Zoltan, Michelle; Riquelme, Erick; Xu, Hanwen; Sahin, Ismet; Castro-Pando, Susana; Montiel, Maria Fernanda; Jiang, Zhengyu; Ling, Jianhua; Gupta, Sonal; Horne, William; et al. Article Gastroenterology (2018)
Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome Chang, Kyle; Taggart, Melissa W.; Reyes-Uribe, Laura; Borras, Ester; Riquelme, Erick; Barnett, Reagan M.; Leoni, Guido; San Lucas, F. Anthony; Catanese, Maria T.; Mori, Federica; et al. Article JAMA ONCOLOGY (2018)
Immunotherapy for Pancreatic Cancer: More Than Just a Gut Feeling Riquelme, Erick; Maitra, Anirban Article CANCER DISCOVERY (2018)
Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations Lin, H. Y.; Izzo, J.; Lee, J. J.; Minna, J. D.; Wistuba, I. I. Article CANCER RESEARCH (2016)
Frequent Coamplification and Cooperation between C-MYC and PVT1 Oncogenes Promote Malignant Pleural Mesothelioma Riquelme, Erick; Suraokar, Milind B.; Mino, Barbara; Lin, Heather Y.; Rice, David C.; Tsao, Anne; Wistuba, Ignacio I. Article Journal of Thoracic Oncology (2014)
VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2-Targeted Therapy Suraokar, M.; Girard, L.; Nilsson, M. B.; Coombes, K. R.; Hong, W. K.; Heymach, J. Article Clinical Cancer Research (2014)
EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non-Small Cell Lung Carcinoma Solis, L. M.; Kadara, H.; Moran, C. A.; Swisher, S. G.; Simon, G. R.; Stewart, D. J. Article Clinical Cancer Research (2013)
Bone Marrow Stromal Cells Modulate Mouse ENT1 Activity and Protect Leukemia Cells from Cytarabine Induced Apoptosis Macanas Pirard, P; Leisewitz, A.; Broekhuizen, R.; Cautivo, K.; Leisewitz, F; Gidi, V; Riquelme E; Montecinos, V. P.; Swett P.; Besa P.; et al. Article ISI SCOPUS PLOS ONE (2012)
A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I Carvajal, C. A.; Montero, T; Fardella C.E.; González P.A.; Kalergis, A.M.; Santos M.J. Article ISI SCOPUS Journal of Endocrinological Investigation (2011)
Increased VEGFR-2 Gene Copy Is Associated with Chemoresistance and Shorter Survival in Patients with Non-Small-Cell Lung Carcinoma Who Receive Adjuvant Chemotherapy Giri, U.; Varella-Garcia, M.; Byers, L. A.; Raso, M. G.; Coombes, K.; Herbst, R. S.; Heymach, J. V. Article CANCER RESEARCH (2011)
T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APC Riquelme EM; Espagnolle, N; Riedel, CA; Valitutti, S Article ISI SCOPUS Proceedings of the National Academy of Sciences of the United States of America (2010)
The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity Riquelme E Article ISI SCOPUS EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
A novel adrenocorticotropin receptor mutation alters its structure and function, causing familial glucocorticoid deficiency Artigas, RA; González A; Riquelme E; Carvajal, CA; Cattani, A; Martinez-Aguayo, A; Perez-Acle, T Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Hierarchical clustering analysis to detect associations between clinical and pathological features of gastric tumors and hypermethylation of suppressor genes Zavala, L; Luengo, V; Ossandon F, Riquelme E.; Backhouse, C; Palma M., Argandoña J.; Cumsille, MA Article Revista médica de Chile (2007)
Pathogenic role of PTEN tumor suppressor gene in ovarian cancer associated to endometriosis Castiblanco, A; Pires, N; Wistuba, I; Riquelme E., Andrade L. Article Revista médica de Chile (2006)
Microsatellite instability and loss of heterozygosity have distinct prognostic value for testicular germ cell tumor recurrence. Velasco, Alfredo; Riquelme, Erick; Schultz, Marcela; Wistuba, Ignacio I; Villarroel, Luis; Koh, Moon S; Leach, Fredrick S Article Cancer biology & therapy (2004)