Man

Viviana Paz Montecinos Acuña

Assistant Professor

Pontificia Universidad Catolica de Chile

Santiago, Chile

Líneas de Investigación


During the last three I focused on understanding the mechanisms that drive the increased angiogenesis associated with two fibroproliferative diseases: benign prostate hyperplasia (BPH) and Prostate Cancer (CaP).

Educación

  •  Biological Sciences, UNIVERSIDAD DE CONCEPCION. Chile, 2006
  •  Physiological Sciences, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2001
  •  Nutricionist, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1996

Experiencia Académica

  •   Academic Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicine

    Santiago, Chile

    2010 - At present

  •   Research Fellow Full Time

    Roswell Park Cancer Institute

    Buffalo, Estados Unidos

    2006 - 2009

Experiencia Profesional

  •   Research Fellow Full Time

    Roswell Park Cancer Institute

    Buffalo, Estados Unidos

    2006 - At present

  •   Assistant Professor Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2011 - At present

Formación de Capital Humano


Thesis advisor

2010- 2012 Javier Cerda Infante., Biochemistry: Impact stromal VEGF-A in in vitro angiogenesis of human invasive prostate cancer

2012- Present Consuelo Zumarán Castagnoli., Biochemistry: Potential role of mesenchymal stem cells within tissue microenvironment in the progression of prostate cancer

2013 Paola Conejeros Mora., Biochemistry: Role of VEGF-A in reactive stroma generation in human prostate cancer

2013 Romina Coronado Monsalves., Biochemistry: Contribution of human prostate stroma in tumor angiogenesis in hormone sensitive prostate cancer


Difusión y Transferencia


N/A


Premios y Distinciones

  •   Prostate Cancer Training Award-Postdoctoral.

    Department of Defense

    Estados Unidos, 2008

    Prostate Cancer Training Award-Postdoctoral.


 

Article (16)

Association of a single-nucleotide polymorphism from chromosome 17q12 with the aggressiveness of prostate cancer in a Hispanic population

Rojas, Pablo A.; Torres-Estay, Verónica; Cerda-Infante, Javier; Montecinos, Viviana P.; Domínguez, Javier; Arenas, José; Godoy, Alejandro S.; San Francisco, Ignacio F.

Article ISI SCOPUS
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY  (2014)

Association of RNASEL and 8q24 variants with the presence and aggressiveness of hereditary and sporadic prostate cancer in a hispanic population

San Francisco IF; Torres-Estay, V; Smalley S.; Cerda-Infante, J; Montecinos, VP; Hurtado C.; Godoy, AS

Article ISI
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE  (2014)

Dynamic expression of the sodium-vitamin C co-transporters, SVCT1 and SVCT2, during perinatal kidney development

Nualart, F.; Castro, T.; Low M; Henriquez, JP; Oyarce, K; Cisternas, P.; Garcia A.; Bertinat R.; Montecinos, VP

Article ISI SCOPUS
Histochemistry and Cell Biology  (2013)

Altered corepressor SMRT expression and recruitment to target genes as a mechanism that change the response to androgens in prostate cancer progression

Godoy, A. S.; Sotomayor, P. C.; Villagrán, M.; Yacoub R.; Montecinos, V. P.; Moser M.; Foster B.A.; Onate S.A.

Article ISI SCOPUS
Biochemical and Biophysical Research Communications  (2012)

Bone Marrow Stromal Cells Modulate Mouse ENT1 Activity and Protect Leukemia Cells from Cytarabine Induced Apoptosis

Macanas Pirard, P; Leisewitz, A.; Broekhuizen, R.; Cautivo, K.; Leisewitz, F; Gidi, V; Riquelme, E; Montecinos, V. P.; Swett P.; Besa P.; et al.

Article ISI SCOPUS
PloS one  (2012)

Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma

Montecinos, V. P.; Godoy A; Hinklin J.; Vethanayagam, R. R.; Smith, G. J.

Article ISI SCOPUS
PloS one  (2012)

Androgen deprivation induces rapid involution and recovery of human prostate vasculature

Godoy A; Montecinos, V. P.; Gray, D. R.; Sotomayor P.; Yau, J. M.; Vethanayagam, R. R.; Singh, S; Mohler, J. L.; Smith, G. J.

Article ISI
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM  (2011)

Biochemical characterization of nuclear receptors for vitamin D-3 and glucocorticoids in prostate stroma cell microenvironment

Hidalgo, AA; Montecinos, VP; Paredes R.; Godoy, AS; McNerney, EM; Tovar, H; Pantoja D.; Johnson, C.; Trump D.

Article ISI SCOPUS
Biochemical and Biophysical Research Communications  (2011)

ABCG2-mediated DyeCycle Violet efflux defined side population in benign and malignant prostate

Mathew, Grinu; Timm, Earl A.; Sotomayor, Paula; Godoy, Alejandro; Montecinos, Viviana P.; Smith, Gary J.; Huss, Wendy J.

Article
CELL CYCLE  (2009)

Androgen Receptor Is Causally Involved in the Homeostasis of the Human Prostate Endothelial Cell

Godoy, Alejandro; Watts, Anica; Sotomayor, Paula; Montecinos, Viviana P.; Huss, Wendy J.; Oñate, Sergio A.; Smith, Gary J.

Article
ENDOCRINOLOGY  (2008)

Mechanistic insights and functional determinants of the transport cycle of the ascorbic acid transporter SVCT2

Godoy A; Ormazabal, V; Moraga-Cid, G; Sotomayor P.; Barra V; Vásquez, Ó.; Montecinos, V.; Mardones L.; Guzman, C.; Villagrán, M.; et al.

Article ISI SCOPUS
JOURNAL OF BIOLOGICAL CHEMISTRY  (2007)

Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione

Montecinos, V.; Guzman P.; Barra V; Villagrán, M.; Munoz-Montesino, C; Sotomayor, K; Escobar, E; Godoy A; Mardones L.; Sotomayor P.; et al.

Article ISI SCOPUS
JOURNAL OF BIOLOGICAL CHEMISTRY  (2007)

A CYTOSOLIC SOURCE OF CALCIUM UNVEILED BY HYDROGEN PEROXIDE WITH RELEVANCE FOR EPITHELIAL CELL DEATH

Barros, Luis; Bittner, Carla; Castro, Joel; Humeres, Alexis; Montecinos, Viviana; Vera, Juan

Article
CELL DEATH AND DIFFERENTIATION  (2004)

Recycling of vitamin C by a bystander effect

Nualart FJ; Montecinos, VP; Godoy, AS; Guaiquil, VH; Golde, DW; Vera, JC

Article ISI SCOPUS
JOURNAL OF BIOLOGICAL CHEMISTRY  (2003)

Elevated expression of glucose transporter-1 in hypothalamic ependymal cells not involved in the formation of the brain-cerebrospinal fluid barrier

Garcia, MDA; Carrasco, M; Godoy A; Reinicke K; Montecinos, VP; Aguayo, LG; Vera, JC; Nualart, F.

Article ISI SCOPUS
JOURNAL OF CELLULAR BIOCHEMISTRY  (2001)

Regulation of adenosine transport by D-glucose in human fetal endothelial cells: involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase

Montecinos, VP; Aguayo, C.; Flores, C.; Wyatt, AW; Pearson, JD; Mann, GE; Sobrevia L.

Article ISI
JOURNAL OF PHYSIOLOGY-LONDON  (2000)

Abstract (3)

Diabetes-induced L-arginine transport is mediated by mitogen-activated protein kinases and nitric oxide in human fetal endothelial cells

VASQUEZ, G.; Olivares, SM; Rojas, S.; Montecinos, VP; Sobrevia L.

Abstract
JOURNAL OF PHYSIOLOGY-LONDON  (2000)

Gestational diabetes-induced nitrobenzylthioinosine-sensitive adenosine transport in human umbilical artery smooth muscle cells

Aguayo, C.; Montecinos, VP; Siow, RCM; Pearson, JD; Sobrevia L.

Abstract
JOURNAL OF PHYSIOLOGY-LONDON  (2000)

Inhibition of adenosine transport involves nitric oxide and mitogen-activated protein kinase in human fetal endothelium from diabetic pregnancy

Montecinos, VP; VASQUEZ, G.; Olivares, SM; Rojas, S.; Aguayo, C.; Sobrevia L.

Abstract
JOURNAL OF PHYSIOLOGY-LONDON  (2000)

Proyecto (1)

Preclinical platform of xenograft models of metastatic human tissues for evaluating anticancer drug sensitivity.

Montecinos, V.

Proyecto
 (0)

Review (1)

Role of androgen and vitamin D receptors in endothelial cells from benign and malignant human prostate

Godoy, AS; Chung, I; Montecinos, VP; Buttyan, R; Johnson CS; Smith, GJ

Review ISI SCOPUS
American Journal of Physiology - Endocrinology and Metabolism  (2013)

8
CORALIA RIVAS

Associated Professor

Pathophysiology

UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

1
Alejandro Yañez

Full professor

Faculty of Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

3
Juan Carcamo

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

1
Maria Bono

Profesor titular

Biologia

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Claudio Aguayo

Profesor Asociado

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

6
Juan Vera

Full professor

Pathophysiology

University of Concepcion

Concepción, Chile

1
Alexis Kalergis

Full Professor

Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

1
Felipe Zuñiga

Profesor Asociado

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
JUAN PABLO HENRIQUEZ

Associate Professor

Cell Biology

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPARTAMENTO DE BIOLOGÍA CELULAR

Concepción, Chile

3
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

1
Marcelo Bustamante

Director

Basisc Sciences

UNIVERSIDAD CATÓLICA DE LA SANTÍSIMA CONCEPCIÓN

CONCEPCIÓN, Chile

1
Brigitte van Zundert

Full Professor

UNIVERSIDAD ANDRÉS BELLO, CENTRO DE INVESTIGACIONES BIOMÉDICAS

Santiago, Chile

1
Carlos Flores

Researcher

Biology Lab

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile

6
Sergio Onate

Associate Professor

Medical Specialties

UNIVERSIDAD DE CONCEPCION, DEPARTAMENTO FISIOPATOLOGIA

concepcion, Chile

1
Romina Bertinat

Technician

Farmacología

Universidad de Concepcion

Concepción, Chile

1
Patricia Macanás

Profesor Asistente Adjunto

Hematology Oncology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

223543432, Chile

1
PAULA GUZMÁN

Profesional Bioquímico

Laboratorio Clínico

Hospital Clínico Regional de Concepción Guillermo Grant Benavente

Concepción, Chile

2
Lorena Mardones

ASSOCIATED PROFESSOR

BASIC SCIENCES AND MORPHOLOGY

UNIVERSIDAD CATOLICA DE LA SANTISIMA CONCEPCION

CONCEPCION, Chile

7
Alejandro Godoy

Associate Professor

Centro de Biología Celular y Biomedicina

Universidad San Sebastián

Santiago, Chile

1
Ignacio San Francisco

URÓLOGO, PROFESOR ASOCIADO

UROLOGÍA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE MEDICINA, DEPARTAMENTO DE ANATOMÍA PATOLÓGICA

Santiago, Chile

1
Pedro Cisternas

Investigador Asociado

Biología Celular

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Bruno Nervi

Associated Professor

Hematology - Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

29
Viviana Montecinos

Assistant Professor

Hematology Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Alejandro Reyes

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

3
Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

1
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Maria Escobar

Postdoctorado

Biología Molecular Vegetal

Universidad de Chile

Santiago , Chile

1
Juan Tapia

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

1
Carola Muñoz

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

2
Javier Cerda Infante

Graduate Student

Biología Celular y Molecular

Pontifica Universidad Católica de Chile

Santiago, Chile

1
Alejandro Hidalgo

Associate Professor

Escuela de Química y Farmacia

Universidad Andres Bello

Santiago, Chile

6
Paula Sotomayor

Investigador

Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Valeska Ormazabal

Profesor asistente

Farmacología

Universidad de Concepción

Concepción, Chile

1
Gustavo Moraga

Profesor Asistente

Departamento de Fisiología

Universidad De Concepción

Concepción, Chile

2
MARCELO VILLAGRAN

Profesor asociado

Departamento de Ciencias Básicas

Universidad Catolica de la Santísima Concepción

Concepcion, Chile

1
ERICK RIQUELME

ASSISTANT PROFESSOR

ENFERMEDADES RESPIRATORIAS

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

2
Verónica Torres

Coordinador Academico

Ciencias Químicas y biológicas

Universidad Bernardo O'Higgins

Santiago , Chile

1
Marcela Low

Docente Investigador

Facultad de Medicina y Ciencia

Universidad San Sebastián

Valdivia, Chile