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Alejandro Samuel Godoy Sánchez

Associate Professor

Universidad San Sebastián

Santiago, Chile

Dr. Godoy's Lab focuses on the study of: 1) the role of the tumor microenvironment, specifically the vasculature, in the progression of prostate cancer, and 2) the role of fructose in the development and progression of prostate cancer.

Medical Technology, UNIVERSIDAD DE LA FRONTERA. Chile, 1996
Physiology, UNIVERSIDAD DE CONCEPCION. Chile, 2000
Cellular and Molecular Biology, UNIVERSIDAD DE CONCEPCION. Chile, 2005

Associate Professor Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Biological Sciences

Santiago, Chile

2012 - 2019
Adjunct Professor of Oncology Other

ROSWELL PARK CANCER INSTITUTE

Buffalo, Estados Unidos

2012 - At present
HRI Scientist (Junior Faculty) Other

ROSWELL PARK CANCER INSTITUTE

Buffalo, Estados Unidos

2010 - 2012
Profesor Asociado Full Time

UNIVERSIDAD SAN SEBASTIAN

Medicina y Ciencia

Santiago, Chile

2019 - At present

HRI Scientist (Junior Faculty) Full Time

Roswell Park Comprehensive Cancer Center

Buffalo, Estados Unidos

2010 - 2012
Adjunct Professor of Oncology Other

Roswell Park Comprehensive Cancer Center

Buffalo, Chile

2012 - At present
Associate Professor Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2012 - At present

MENTORING-UNDERGRADUATE

1. BIOCHEMISTRY
Jaime Lizama (University of Valparaiso)
Catalina Asencio (PUC)
Carolina Gaete (University of Chile).
Tino Meneses (UNAB)
Luz Emilia Flores (PUC)
Vanessa Silva (UNAB)
Jenifer Aranda (USS)

2. BIOLOGY
Hugo Muñoz (PUC)
Catalina Garay (University of Valparaiso)
Marcia Arredondo (PUC)
Carla Cembrano (PUC).

3. MEDICAL TECHNOLOGY
Aaron Claveria (UNAB)
Nicolás Durán (UNAB)
Diego Saavedra (UNAB)
Edson Reyes (UNAB)
Daniel Silva (UNAB)
Guillermo Delgado (UNAB)
Paula Venegas (2015)
Carolina Acha (UNAB)
Arantxa Urrestarazu (UNAB)
Marta Verdugo (UNAB).
Maria José Vives (UNAB)
Gissella Reyes (UNAB)
Romina Labrin (UNAB)
Nicole Martinez (UNAB)
Carolina Ipanaque (UNAB)
Andrea Meneses (UNAB)
Florencia Benito (UNAB)
Miguel Alarcón (UNAB)
Nicolás Torres (USS)
Francisca Saldías (USS)

MENTORING-GRADUATE

Dr. Daniela Carreño (Postdoctoral, PUC)
Dr. Veronica Torres (PhD in Physiology, PUC)
Dr. Nestor Corro (PhD in Physiology, PUC)
Dr. Viviana Orellana (PhD in Medical Sciences, UDD)
Dr. Carolina Echeverría (PhD in Biomedicine, UAndes)
Dr. (c) Luz Emilia Flores (PhD in Cellular Biology and Biomedicine, USS)

MEETING ORGANIZATION

2014: Workshop: Prostate Cancer Research: New Determinant of Tumor Progression.
2015: Workshop: Cancer Biology: New Advances in Angiogenesis.
2017: Symposium: Preclinical Models of Human Cancer.
2018: Workshop: Mechanisms of Intercellular Communication in Cancer.
2018: Symposium, Chilean Society for Cell Biology: Tumor Microenvironment and Cancer Biology.
2023: Workshop, Metabolismo y Nutrición en Salud y Enfermedad.

PATENTS

1. “Use of 5-alpha-reductase type 3 In Diagnosis of Malignant Prostate”
61/254,329 US Patent awarded
J. Mohler, M. Titus, A. Godoy, O. Kozyreva, E. Kawinski, Y. Li.

2. “anti-angiogenic peptides from endogenous PSA protein”
Provisional 61/368,406 US Patent Pending
G. Smith, K. Chadha, A. Godoy, V. Montecinos, R. Zou.

Academic Excellence Award

UNIVERSIDAD DE LA FRONTERA

Chile, 1992

Academic Excellence Fellowship 100%. Funded by the Government of Chile and the University of La Frontera.
CONICYT Graduate Fellowship (M.Sc.)

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 1998

CONICYT Fellowship for Master of Biological Science mention Physiology. From 1998 to 2000.
CONICYT Pre-Doctoral Fellowship (Ph.D.)

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2000

Fellowship for PhD in Biological Sciences mention Cellular and Molecular Biology. From 2000 to 2004.
MECESUP Travel and Research Award

UNIVERSIDAD DE CONCEPCION

Chile, 2003

Research Training at the Center for Research in Reproductive Physiology, Department of Cell Biology and Physiology, School of Medicine, University of Pittsburgh, Pittsburgh, USA.
SBUR Travel Award

Society of Basic Urologic Research

Estados Unidos, 2007

Travel Award to Present at the Annual Meeting of the Society for Basic Urologic Research, USA. Selected as Oral Expositor.
Prostate Cancer Training Award-Postdoctoral

U.S. Department of Defense

Chile, 2008

Fellowship to complete Post-Doctoral training at Roswell Park Cancer Institute. From 2008 to 2010.
Attraction and Integration Program for Advanced Human Capital in the Academia

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2011

Awarded by the Goverment of Chile. This Fellowship was declined.
Visiting Professor

UNIVERSIDAD DE LA FRONTERA

Chile, 2013

Awarded by the University of la Frontera, PhD Program in Applied Cellular and Molecular Biology.
Travel Award UNESCO/ICRO

Escuela de Neurociencia

Uruguay, 1999

Meeting of the Escuela Latinoamericana de Neurociencia.
Travel Award ICGEB

INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTIFICAS

Venezuela, 2000

Travel award to assist to an international course on cell death and cancer.
Travel Award UNESCO/ICRO

Universidad Federal de Rio de Janeiro

Brasil

Travel Award to assist to an international course on cellular proliferation.


Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium Omar, Intan Sofia; Adenan, Noor Azmi Mat; Godoy, Alejandro; Teo, Ik Hui; Gunasagran, Yogeeta; Chung, Ivy Article ISI BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)
Active Surveillance in Prostate Cancer: Current and Potentially Emerging Biomarkers for Patient Selection Criteria Sotomayor, Paula C. C.; Aguilar, Juan C. C.; Mujica, Karen; Zuniga, Alvaro; Godoy, Alejandro S. S.; Smith, Gary J. J.; Mohler, James L. L.; Vitagliano, Gonzalo; San Francisco, Ignacio F. F. Article ISI UROLOGIA INTERNATIONALIS (2022)
Pharmacological targets for the induction of ferroptosis: Focus on Neuroblastoma and Glioblastoma Ferrada, Luciano; Barahona, Maria Jose; Salazar, Katterine; Godoy, Alejandro S.; Vera, Matias; Nualart, Francisco Article ISI FRONTIERS IN ONCOLOGY (2022)
The Differential Paracrine Role of the Endothelium in Prostate Cancer Cells Torres-Estay, Veronica; Mastri, Michalis; Rosario, Spencer; Fuenzalida, Patricia; Echeverria, Carolina E.; Flores, Emilia; Watts, Anica; Cerda-Infante, Javier; Montecinos, Viviana P.; Sotomayor, Paula C.; Amigo, Julio; Escudero, Carlos; Nualart, Francisco; Ebos, John M. L.; Smiraglia, Dominic J.; Godoy, Alejandro S. Article ISI CANCERS (2022)
Dietary fructose promotes prostate cancer growth Carreno, DV; Corro, N; Cerda-Infante, J; Echeverria, C.; Asencio-Barria, C; Torres-Estay, V; Mayorga-Weber, G; Rojas, P; Veliz, L; Cisternas, P; Montecinos, VP; San Francisco, I; Varas-Godoy, M; Sotomayor, P; Castro, M; Nualart, F; Inestrosa, N; Godoy, A Article CANCER RESEARCH (2021)
Hexose Transporters in Cancer: From Multifunctionality to Diagnosis and Therapy Echeverria, Carolina; Nualart, Francisco; Ferrada, Luciano; Smith, Gary J.; Godoy, Alejandro S. Article ISI TRENDS IN ENDOCRINOLOGY AND METABOLISM (2021)
Advantages in Wound Healing Process in Female Mice Require Upregulation A(2A)-Mediated Angiogenesis under the Stimulation of 17 beta-Estradiol Troncoso, Felipe; Herlitz, Kurt; Acurio, Jesenia; Aguayo, Claudio; Guevara, Katherine; Ovidio Castro, Fidel; Godoy, Alejandro S.; San Martin, Sebastian; Escudero, Carlos Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Dehydroascorbic acid, the oxidized form of vitamin C, improves renal histology and function in old mice Forman, Katherine; Martinez, Fernando; Cifuentes, Manuel; Fernandez, Marcos; Bertinat, Romina; Torres, Pablo; Salazar, Katterine; Godoy, Alejandro; Nualart, Francisco Article ISI JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Deletion of the adenosine A(2A)receptor increases the survival rate in a mice model of polymicrobial sepsis Merino, Miguel; San Martin, Sebastian; Sandana, Pedro; Herlitz, Kurt; Aguayo, Claudio; Godoy, Alejandro; Torres-Vergara, Pablo; Gonzalez, Marcelo; Troncoso, Felipe; Acurio, Jesenia; Escudero, Carlos Article ISI PURINERGIC SIGNALLING (2020)
Recapitulation of prostate tissue cell type-specific transcriptomes by anin vivoprimary prostate tissue xenograft model Gross, Nelson T.; Wang, Jianmin; Fiandalo, Michael V.; Cortes Gomez, Eduardo; Watts, Anica; Godoy, Alejandro S.; Smith, Gary J.; Wu, Yue Article ISI PLOS ONE (2020)
Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation Arce, M.; Pinto, M. P.; Galleguillos, M.; Munoz, C.; Lange, S.; Ramirez, C.; Erices, R.; Gonzalez, P.; Velasquez, E.; Tempio, F.; Lopez, M. N.; Salazar-Onfray, F.; Cautivo, K.; Kalergis, A. M.; Cruz, S.; Lladser, A.; Lobos-Gonzalez, L.; Valenzuela, G.; Olivares, N.; Saez, C.; Koning, T.; Sanchez, F. A.; Fuenzalida, P.; Godoy, A.; Contreras Orellana, P.; Leyton, L.; Lugano, R.; Dimberg, A.; Quest, A. F. G.; Owen, G. I. Article CANCERS (2019)
Fructose and prostate cancer: toward an integrated view of cancer cell metabolism Carreno, Daniela; Corro, Nestor; Torres-Estay, Veronica; Veliz, Loreto P.; Jaimovich, Rodrigo; Cisternas, Pedro; San Francisco, Ignacio F.; Sotomayor, Paula C.; Tanasova, Marina; Inestrosa, Nibaldo C.; Godoy, Alejandro S. Article ISI SCOPUS PROSTATE CANCER AND PROSTATIC DISEASES (2019)
Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure Santander, Nicolas; Lizama, Carlos; Murgas, Leandro; Contreras, Sebastian; Martin, Alberto J. M.; Molina, Paz; Quiroz, Alonso; Rivera, Katherine; Salas-Perez, Francisca; Godoy, Alejandro; Rigotti, Attilio; Busso, Dolores Article ISI SCOPUS BMC GENOMICS (2018)
Androgens modulate male-derived endothelial cell homeostasis using androgen receptor-dependent and receptor-independent mechanisms Torres-Estay, Verónica; Carreño, Daniela V.; Fuenzalida, Patricia; Watts, Anica; San Francisco, Ignacio F.; Montecinos, Viviana P.; Sotomayor, Paula C.; Ebos, John; Smith, Gary J.; Godoy, Alejandro S. Article ISI SCOPUS ANGIOGENESIS (2017)
Combination of the histone deacetylase inhibitor vorinostat with bevacizumab in patients with clear-cell renal cell carcinoma: a multicentre, single-arm phase I/II clinical trial Pili, Roberto; Liu, Glenn; Chintala, Sreenivasulu; Verheul, Hendrick; Rehman, Shabnam; Attwood, Kristopher; Lodge, Martin A; Wahl, Richard; Martin, James I; Miles, Kiersten Marie; Paesante, Silvia; Adelaiye, Remi; Godoy, Alejandro; King, Serina; Zwiebel, James; Carducci, Michael A Article ISI SCOPUS BRITISH JOURNAL OF CANCER (2017)
Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression Erices, Rafaela; Cubillos, Sofía; Aravena, Raúl; Santoro, Felice; Marquez, Monica; Orellana, Renan; Ramírez, Carolina; González, Pamela; Fuenzalida, Patricia; Loreto Bravo, María; Oliva, Bárbara; Kato, Sumie; Ibañez, Carolina; Brañes, Jorge; Bravo, Erasmo; Alonso, Catalina; García, Karen; Arab, Clemente; Torres, Vicente A.; Godoy, Alejandro S.; Pereira, Jaime; Bustos, Galdo; Cesar Cardenas, Julio; Cuello, Mauricio A.; Owen, Gareth I. Article ISI SCOPUS ONCOTARGET (2017)
Pro-angiogenic Role of Insulin: From Physiology to Pathology Escudero, Carlos A.; Herlitz, Kurt; Troncoso, Felipe; Guevara, Katherine; Acurio, Jesenia; Aguayo, Claudio; Godoy, Alejandro S.; González, Marcelo Article ISI SCOPUS FRONTIERS IN PHYSIOLOGY (2017)
Anti-angiogenic activity of PSA-derived peptides Chadha, KC; Nair, B; Godoy A.; Rajnarayanan, R; Nabi, E; Zhou R.; Patel, NR; Aalinkeel, R; Schwartz, SA; Smith, GJ Article ISI SCOPUS Prostate (2015)
Selective targeting of bioengineered platelets to prostate cancer vasculature: new paradigm for therapeutic modalities Montecinos, VP; Morales CH; Fischer TH; Burns, S.; San Francisco IF; Godoy, AS; Smith, GJ Article ISI SCOPUS Journal of Cellular and Molecular Medicine (2015)
5 alpha-Reductase Type 3 Enzyme in Benign and Malignant Prostate Titus, MA; Li Y.; Kozyreva, OG; Maher, V; Godoy A.; Smith, GJ; Mohler, JL Article ISI PROSTATE (2014)
Association of a single-nucleotide polymorphism from chromosome 17q12 with the aggressiveness of prostate cancer in a Hispanic population Rojas, Pablo A.; Torres-Estay, Verónica; Cerda-Infante, Javier; Montecinos, Viviana P.; Domínguez, Javier; Arenas, José; Godoy, Alejandro S.; San Francisco, Ignacio F. Article ISI SCOPUS JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2014)
Association of RNASEL and 8q24 variants with the presence and aggressiveness of hereditary and sporadic prostate cancer in a Hispanic population. San Francisco IF1, Rojas PA, Torres-Estay V, Smalley S, Cerda-Infante J, Montecinos VP, Hurtado C, Godoy AS Article J Cell Mol Med. (2014)
Association of RNASEL and 8q24 variants with the presence and aggressiveness of hereditary and sporadic prostate cancer in a Hispanic population. San Francisco, Ignacio F; Rojas, Pablo A; Torres-Estay, Verónica; Smalley, Susan; Cerda-Infante, Javier; Montecinos, Viviana P; Hurtado, Claudia; Godoy, Alejandro S Article Journal of cellular and molecular medicine (2014)
Androgen-responsive Serum Response Factor target genes regulate prostate cancer cell migration Verone, A. R.; Duncan, K.; Godoy, A.; Yadav, N.; Bakin, A.; Koochekpour, S.; Jin, J. P.; Heemers, H. V. Article Carcinogenesis (2013)
Combinatorial antitumor effect of HDAC and the PI3K-Akt-mTOR pathway inhibition in a Pten defecient model of prostate cancer. Ellis L1, Ku SY, Ramakrishnan S, Lasorsa E, Azabdaftari G, Godoy A, Pili R. Article Oncotarget (2013)
Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer Ellis, L; Ku, SY; Ramakrishnan, S; Lasorsa, E; Azabdaftari, G; Godoy A.; Pili, R. Article ISI SCOPUS Oncotarget (2013)
Human Choroid Plexus Papilloma Cells Efficiently Transport Glucose and Vitamin C Ulloa, V.; Garcia-Robles, M.; Martinez, F.; Salazar, K.; Reinicke, K.; Perez, F.; Godoy, D. F.; Godoy, A. S.; Nualart, F. Article Journal of neurochemistry (2013)
Human choroid plexus papilloma cells efficiently transport glucose and vitamin C. Ulloa, Viviana; García-Robles, María; Martínez, Fernando; Salazar, Katterine; Reinicke, Karin; Pérez, Fernando; Godoy, David F; Godoy, Alejandro S; Nualart, Francisco Article Journal of neurochemistry (2013)
Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5 alpha-reductase inhibitors Wu, Y; Godoy A.; Azzouni, F; Wilton, JH; Ip, C; Mohler, JL Article ISI SCOPUS Prostate (2013)
Prostate Cancer Cells Differ in Testosterone Accumulation, Dihydrotestosterone Conversion, and Androgen Receptor Signaling Response to Steroid 5 alpha-Reductase Inhibitors Godoy A, Wu, Y; Azzouni, F; Wilton, JH; Ip, C; Mohler, JL Article The Prostate (2013)
Role of Androgen and Vitamin D Receptors in Endothelial Cells from Benign and Malignant Human Prostate Godoy, A. S.; Chung, I.; Montecinos, V. P.; Buttyan, R.; Johnson, C. S.; Smith, G. J. Article American journal of physiology. Endocrinology and metabolism (2013)
Role of androgen and vitamin D receptors in endothelial cells from benign and malignant human prostate. Godoy, Alejandro S; Chung, Ivy; Montecinos, Viviana P; Buttyan, Ralph; Johnson, Candace S; Smith, Gary J Article American journal of physiology. Endocrinology and metabolism (2013)
Altered corepressor SMRT expression and recruitment to target genes as a mechanism that change the response to androgens in prostate cancer progression Godoy, A. S.; Sotomayor, P. C.; Villagrán M.; Yacoub R.; Montecinos, V. P.; McNerney E.M.; Moser M.; Foster B.A.; Onate S.A. Article ISI SCOPUS Biochemical and Biophysical Research Communications (2012)
Cellular distribution of Glut-1 and Glut-5 in benign and malignant human prostate tissue Reinicke K; Sotomayor P.; Cisterna, P; Delgado C.; Nualart, F.; Godoy A. Article ISI SCOPUS Journal of Cellular Biochemistry (2012)
Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma Montecinos, VP; Godoy A.; Hinklin J.; Vethanayagam, RR; Smith, GJ Article PLOS ONE (2012)
Primary Xenografts of Human Prostate Tissue as a Model to Study Angiogenesis Induced by Reactive Stroma Montecinos, V. P.; Godoy A.; Hinklin J.; Vethanayagam, R. R.; Smith, G. J. Article ISI SCOPUS PLOS ONE (2012)
The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases Azzouni, F.; Godoy, A.; Li, Y.; Mohler, J. Article Advances in urology (2012)
5 alpha-Reductase Type 3 Expression in Human Benign and Malignant Tissues: A Comparative Analysis During Prostate Cancer Progression Godoy A.; Kawinski, E; Li Y.; Oka, D; Alexiev, B; Azzouni, F; Titus, MA; Mohler, JL Article ISI PROSTATE (2011)
5alpha-reductase type 3 expression in human benign and malignant tissues: a comparative analysis during prostate cancer progression Godoy, A. S.; Kawinski, E.; Li, Y.; Oka, D.; Alexiev, B.; Azzouni, F.; Titus, M. A.; Mohler, J. L. Article The Prostate (2011)
Androgen deprivation induces rapid involution and recovery of human prostate vasculature Godoy A.; Montecinos, V. P.; Gray, D. R.; Sotomayor P.; Yau, J. M.; Vethanayagam, R. R.; Singh, S; Mohler, J. L.; Smith, G. J. Article ISI AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
Androgen deprivation induces rapid vascular involution and recovery in the short-term prostate primary xenograft model Godoy, A; Montecinos, V; Gray, D; Sotomayor, P; Yau, J; Vethanayagam, R; Singh, S; Mohler, J; Smith, G Article Am J Physiol Endo Metab (2011)
Biochemical characterization of nuclear receptors for vitamin D3 and glucocorticoids in prostate stroma cell microenvironment. Hidalgo, A; Montecinos, V; Paredes, R; Godoy, A; Mc.Nerney, E; Tovar, H; Pantoja, D; Johnson, C; Trump, D; Onate, S Article Biochem Biophys Res Commun (2011)
Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblast and paracrine signaling to prostate cancer Tanner, M; Welliver Jr, R; Chen, M; Shtutman, M; Godoy, A; Smith, G; Mian, B; Buttyan, R Article PLoS One (2011)
Enzymatic activity of free-prostate-specific antigen (f-PSA) is not required for some of its physiological activities Chadha, K. C.; Nair, B. B.; Chakravarthi, S.; Zhou, R.; Godoy, A.; Mohler, J. L.; Aalinkeel, R.; Schwartz, S. A.; Smith, G. J. Article The Prostate (2011)
Enzymatic Activity of Free-Prostate-SpecificAntigen (f-PSA) Is Not Required for Some of its Physiological Activities Chadha, KC; Nair, BB; Chakravarthi, S; Zhou R.; Godoy A.; Mohler, JL; Aalinkeel, R; Schwartz, SA; Smith, GJ Article ISI PROSTATE (2011)
Histidine Residues in the Na+-coupled Ascorbic Acid Transporter-2 (SVCT2) Are Central Regulators of SVCT2 Function, Modulating pH Sensitivity, Transporter Kinetics, Na+ Cooperativity, Conformational Stability, and Subcellular Localization Ormazabal, V; Zuniga, FA; Escobar, E; Aylwin, C; Salas Burgos A.; Godoy A.; Reyes, AM; Vera, JC; Rivas, CI Article ISI SCOPUS Journal of Biological Chemistry (2010)
Histidine Residues in the Na+-coupled Ascorbic Acid Transporter-2 (SVCT2) Are Central Regulators of SVCT2 Function, Modulating pH Sensitivity, Transporter Kinetics, Na+ Cooperativity, Conformational Stability, and Subcellular Localization Ormazabal V.; Zuniga, FA; Escobar, E; Aylwin C.; Salas-Burgos A.; Godoy A.; Reyes, AM; Vera, JC; Rivas, CI Article JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
ABCG2-Mediated dyecycle violet efflux defined side population in benign and malignant prostate Mathew, G; Timm Jr, E; Sotomayor, P; Godoy, A; Montecinos V; Smith, G; Huss, W Article Cell Cycle (2009)
Nutritional channels in breast cancer Godoy A.; Salazar K.; Figueroa C.; Smith, GJ; Garcia, MD; Nualart, FJ Article Journal of Cellular and Molecular Medicine (2009)
Nutritional channels in breast cancer Godoy A.; Salazar, K.; Figueroa C.; Smith, GJ; Garcia, MD; Nualart FJ Article ISI SCOPUS JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Oct4A is expressed by a subpopulation of prostate neuroendocrine cells Sotomayor, P; Godoy, A; Smith, G; Huss, W Article The prostate (2009)
Androgen receptor is causally involved in the homeostasis of the human prostate endothelial cell Godoy, A; Watts, A; Sotomayor, P; Montecinos, V; Huss, W; Onate, S; Smith, G Article Endocrinology (2008)
Mechanistic insights and functional determinants of the transport cycle of Na+-ascorbic acid cotransporter SVCT2: Activation by Sodium and Absolute dependence on bivalent cations. Godoy A, Ormazabal V, Moraga-Cid G, Zuñiga F, Sotomayor P, Barra V, Vásquez O, Montecinos V, Mardones L, Guzmán C, Villagrán M, Aguayo L, Onate S, Reyes A, Carcamo JG, Rivas CI, Vera JC. Article J Biol Chem (2007)
Mechanistic insights and functional determinants of the transport cycle of the ascorbic acid transporter SVCT2 Godoy A.; Ormazabal, V; Moraga-Cid, G; Zuniga, FA; Sotomayor P.; Barra V; Vásquez O.; Montecinos, V.; Mardones L.; Guzmán C; Villagrán M.; Aguayo, LG; Onate, SA; Reyes, AM; Carcamo, JG; Rivas, CI; Vera, JC Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Stromal-epithelial cell interactions and androgen receptor-coregulator recruitment is altered in the tissue microenvironment of prostate cancer Cano, Patricia; Godoy, Alejandro; Escamilla, Rosalba; Dhir, Rajiv; Onate, Sergio A. Article ISI CANCER RESEARCH (2007)
Stromal-epithelial cell interactions and AR-coregulator recuitment is altered in the tissue microenvironment of prostate cancer Cano P, Godoy A, Escamilla R, Dhir R, Onate S. Article Cancer Res (2007)
Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione Montecinos, V.; Guzman P.; Barra V; Villagrán M.; Munoz-Montesino, C; Sotomayor, K; Escobar, E; Godoy A.; Mardones L.; Sotomayor P.; Guzmán C; Vásquez O.; Gallardo V.; van Zundert, B; Bono, MR.; Onate, SA; Bustamante, M; Carcamo, JG; Rivas, CI; Vera, JC Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess survival of glutathione Montecinos V, Guzmám P, Barra V, Villagrán M, Muñoz C, Sotomayor K, Escobar E, Godoy A, Mardones L, Sotomayor P, Guzmán C, Vásquez O, Gallardo V, Van Zunder B, Bono M, Onate S, Bustamante M, Carcamo JG, Rivas C, Vera JC. Article J Biol Chem (2007)
Differential subcellular distribution of glucose transporters GLUT1-6 and GLUT9 in human cancer: Ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissues Godoy A.; Ulloa V.; Rodriguez,F; Reinicke K; Yanez, AJ; Garcia, MD; Medina RA.; Carrasco M.; Barberis S.; Castro, T.; Martinez F.; Koch X; Vera, JC; Poblete, MT; Figueroa, CD; Peruzzo, B; Pérez F.; Nualart, F. Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Differential subcellular distribution of glucose transporters GLUT1-GLUT6 and GLUT9 in human cancer: Ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissue. Godoy A, Ulloa V, Rodríguez F, Reinicke K, Yañez A, García M, Medina R, Carrasco M, Barberis S, Castro T, Martínez F, Koch X, Vera JC, Poblete M, Figueroa C, Peruzzo B, Pérez F, Nualart F. Article J Cell Physiol (2006)
Redefining the facilitated transport of mannose in human cells: Absence of a glucose-insensitive, high-affinity facilitated mannose transport system Rodríguez, P.; Rivas, CI; Godoy A.; Villanueva, M.; Fischbarg, J; Vera, JC; Reyes, AM Article ISI SCOPUS BIOCHEMISTRY (2005)
Redefining the facilitated transport of mannose in human cells: Absence of a glucose-insensitive, high-affinity facilitated mannose transport system. Rodriguez P, Rivas C, Godoy A, Villanueva M, Fischbarg J, Vera JC, Reyes A. Article Biochemistry (2005)
Recycling of vitamin C by a bystander effect Nualart F, Rivas C, Montecinos V, Godoy A, Guaiquil V, Golde D, Vera JC. Article J Biol Chem (2003)
Elevated expression of glucose transporter-1 in hypothalamic ependymal cells not involved in the formation of the brain-cerebrospinal fluid barrier Garcia, MDA; Carrasco M.; Godoy A.; Reinicke K; Montecinos, VP; Aguayo, LG; Tapia, JC; Vera, JC; Nualart, F. Article ISI SCOPUS JOURNAL OF CELLULAR BIOCHEMISTRY (2001)
Elevated expression of the glucose transporter-1 in hypotalamic ependymal cells not involved in barrier function. García M, Carrasco M, Godoy A, Montecinos V, Reinicke K, Aguayo L, Tapia JC, Vera JC, Nualart F. Article J Cell Biochem (2001)
Expression of the hexose transporters GLUT1 and GLUT2 during the early development of the human brain. Nualart F, Godoy A, Reinicke K. Article Brain Res (1999)


Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium (vol 328, pg 133, 2022) Omar, Intan Sofia; Adenan, Noor Azmi Mat; Godoy, Alejandro; Teo, Ik Hui; Gunasagran, Yogeeta; Chung, Ivy Correction ISI BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2023)


Consorcio Tecnológico IFAN=> Desarrollo Sinérgico de Ingredientes funcionales y Aditivos Naturales. P4. Desarrollo de un ingrediente funcional para el tratamiento del cáncer de próstata CORFO (IF43769-0) Proyecto 2016-2021 Investigador(a)
PARACRINE EFFECT OF THE ENDOTHELIUM ON PROSTATE CANCER CELLS AND ITS ROLE DURING TUMOR PROGRESSION FONDECYT (1161115) Proyecto 2016-2019 Inv. Responsable
Predictive test of prostate cancer progression based on stromal expression signature Vicerrectoría de Investigación-PUC Proyecto 2015-2016 Coinvestigador(a)
ROL DE FRUCTOSA EN CÁNCER DE PRÓSTATA FONDECYT (3160717) Proyecto 2015-2018 Inv. Patrocinante
Rol del Receptor de Andrógeno en Hiperplasia Prostática Benigna y su Utilidad como Nuevo Blanco Terapéutico en Hombres Mayores de 65 años con Falla a Tratamiento Médico Vicerrectoría de Investigación-PUC (001) Proyecto 2015-2016 Coinvestigador(a)
VEGF-A SIGNALING IN CARCINOMA-ASSOCIATED FIBROBLASTS=> ROLE IN REACTIVE STROMA GENERATION AND METASTATIC POTENTIAL" FONDECYT (1150397) Proyecto 2015-2018 Coinvestigador(a)
Apoyo a la Formación de Redes Internacionales entre Centros de Investigación PCI (130033) Proyecto 2014-2015 Director(a)
Role of Fructose in Prostate Cancer Department of Defense (DOD) USA (W81XWH-12-1-0341) Proyecto 2014-2017 Inv. Principal
Busqueda del estado del arte para patentamiento/licenciamiento Vicerectoria (001) Proyecto 2013-2013 Inv. Principal
ROLE OF ADRENAL ANDROGENS IN PROSTATE VASCULATURE FONDECYT (1130051) Proyecto 2013-2016 Inv. Responsable
Clinical Relevance of Androgen Regulators in Castration Resistant Prostate Cancer Roswell Park Alliance Foundation Proyecto 2012-2013 Coinvestigador(a)
Androgen Effects on Human Prostate Endothelial Cells Department of Defense (DOD) USA (PC073761) Proyecto 2008-2010 Inv. Principal


Biological role of fructose in the male reproductive system: Potential implications for prostate cancer Echeverria, Carolina E.; Oyarzun, Vanessa I.; Lopez-Cortes, Andres; Cancino, Jorge; Sotomayor, Paula C.; Goncalves, Marcus D.; Godoy, Alejandro S. Review ISI PROSTATE (2023)
Direct Intercellular Communications and Cancer: A Snapshot of the Biological Roles of Connexins in Prostate Cancer Asencio-BarrÃa C.; Defamie N.; SÃ¡ez J.C.; Mesnil M.; Godoy, A. S. Review ISI SCOPUS CANCERS (2019)
Exercise and prostate cancer: From basic science to clinical applications Campos, C; Sotomayor, P; Jerez, D; Gonzalez, J; Schmidt, CB; Schmidt K.; Banzer, W; Godoy, AS Review ISI SCOPUS PROSTATE (2018)
Androgen receptor in human endothelial cells Torres-Estay, V; Carreno, DV; Francisco, IFS; Sotomayor P.; Godoy, AS; Smith, GJ Review ISI SCOPUS Journal of Endocrinology (2015)

Alejandro Godoy

Associate Professor

Centro de Biología Celular y Biomedicina

Universidad San Sebastián

Santiago, Chile

Paula Sotomayor

Investigador

Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

CORALIA RIVAS

Associated Professor

Pathophysiology

UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

Viviana Montecinos

Assistant Professor

Hematology Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Alejandro Reyes

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

Juan Vera

Full professor

Pathophysiology

University of Concepcion

Concepción, Chile

FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Sergio Onate

Associate Professor

Medical Specialties

UNIVERSIDAD DE CONCEPCION, DEPARTAMENTO FISIOPATOLOGIA

concepcion, Chile

Carlos Escudero

Full Professor

Basic Sciences Department

Universidad del Bio Bio

Chillan, Chile

Juan Carcamo

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

Alexis Salas

Assistant Professor

Pharmacology

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

Lorena Mardones

ASSOCIATED PROFESSOR

BASIC SCIENCES AND MORPHOLOGY

UNIVERSIDAD CATOLICA DE LA SANTISIMA CONCEPCION

CONCEPCION, Chile

Pablo Torres

Profesor Asistente

Farmacia

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

Sebastian San Martin

Profesor Titular

Anatomía

UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

Carlos Figueroa

Head

Anatomy, Histology and Pathology

Universidad Austral de Chile

Valdivia, Chile

Alejandro Yanez

Full professor

Faculty of Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Felipe Zuñiga

Profesor Asistente

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Maria Escobar

Postdoctorado

Biología Molecular Vegetal

Universidad de Chile

Santiago , Chile

Valeska Ormazabal

Profesor asistente

Farmacología

Universidad de Concepción

Concepción, Chile

Patricia Fuenzalida

Lab Manager

Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

MARCELO VILLAGRAN

Profesor asociado

Departamento de Ciencias Básicas

Universidad Catolica de la Santísima Concepción

Concepcion, Chile

Nicolás Santander

Assistant Professor

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

Pedro Cisternas

Investigador Asociado

Biología Celular

Pontificia Universidad Católica de Chile

Santiago, Chile

Dolores Busso

Associate Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - ESCUELA DE MEDICINA - DEPTO DE GASTROENTEROLOGÍA

Santiago, Chile

Alberto Martin

Associate professor

Centro Ciencia & Vida

Universidad San Sebastián

Santiago, Chile

Rafaela Erices

Postdoctorante

Ginecología y Obstetricia

Pontificia Universidad Católica de Chile

Santiago, Chile

Gustavo Moraga

Profesor Asistente

Departamento de Fisiología

Universidad De Concepción

Concepción, Chile

Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

Juan Tapia

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

Maria Bono

Profesor titular

Biologia

UNIVERSIDAD DE CHILE

Santiago, Chile

Viviana Ulloa

Profesional Superior

Dirección de Estudios Estratégicos

Universidad de Concepción

Concepción, Chile

Claudio Morales

Bioquímico

Hospital Dr. Félix Bulnes Cerda

Santiago, Chile

Verónica Torres

Coordinador Academico

Ciencias Químicas y biológicas

Universidad Bernardo O'Higgins

Santiago , Chile

KATHERINE FORMAN

Profesor Asociado

nutrition and dietetics

universidad de concepción

concepción, Chile

Marcos Fernandez

Profesor Asociado

Farmacia

FACULTAD DE FARMACIA, UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Ignacio San Francisco

URÓLOGO, PROFESOR ASOCIADO

UROLOGÍA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE MEDICINA, DEPARTAMENTO DE ANATOMÍA PATOLÓGICA

Santiago, Chile

Javier Cerda Infante

Graduate Student

Biología Celular y Molecular

Pontifica Universidad Católica de Chile

Santiago, Chile

PAULA GUZMÁN

Profesional Bioquímico

Laboratorio Clínico

Hospital Clínico Regional de Concepción Guillermo Grant Benavente

Concepción, Chile

Maria Poblete

Profesor Auxiliar

Anatomia, Histologia y Patologia

Universidad Austral de Chile

Valdivia, Chile

María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Romina Bertinat

Technician

Farmacología

Universidad de Concepcion

Concepción, Chile

Katterine Salazar

Associate Professor

Cell Biology

University of Concepcion

Concepción, Chile

Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Fernando Martinez

Assistant Professor

Cell Biology

Universidad de Concepción

Concepción, Chile

CAROLINA DELGADO

Encargado de proyectos de desarrollo de Unidad de Anatomía Patológica

CR Diagnóstico Terapéutico

Hospital Regional Concepción HGGB

Concepcion, Chile

ROSALBA ESCAMILLA

Investigador asociado

Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Carola Muñoz

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

RENAN ORELLANA

Investigador

Ciencias Químicas y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

Claudio Aguayo

Profesor Asociado

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

Marcelo Bustamante

Director

Basisc Sciences

UNIVERSIDAD CATÓLICA DE LA SANTÍSIMA CONCEPCIÓN

CONCEPCIÓN, Chile

Brigitte van Zundert

Full Professor

UNIVERSIDAD ANDRÉS BELLO, CENTRO DE INVESTIGACIONES BIOMÉDICAS

Santiago, Chile

Francisca Salas

Asistant Professor

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

Luciano Ferrada

Investigador

Biología celular

Universidad de Concepción

Concepcion, Chile

Katherine Rivera

PhD (c) student in Medical Science

Pontificia Universidad Católica de Chile

Santiago, Chile

Christian Campos

Decano

Universidad Andrés Bello

santiago, Chile

María José Barahona

Investigadora posdoctoral

Biología Celular

Universidad de Concepción

Concepción, Chile

Leandro Murgas

Bioinformático

Meristem Spa.

Huechuraba, Chile

Alejandro Samuel Godoy Sánchez

Líneas de Investigación

Educación

Medical Technology, UNIVERSIDAD DE LA FRONTERA. Chile, 1996

Physiology, UNIVERSIDAD DE CONCEPCION. Chile, 2000

Cellular and Molecular Biology, UNIVERSIDAD DE CONCEPCION. Chile, 2005

Experiencia Académica

Associate Professor Full Time

Adjunct Professor of Oncology Other

HRI Scientist (Junior Faculty) Other

Profesor Asociado Full Time

Experiencia Profesional

HRI Scientist (Junior Faculty) Full Time

Adjunct Professor of Oncology Other

Associate Professor Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Academic Excellence Award

CONICYT Graduate Fellowship (M.Sc.)

CONICYT Pre-Doctoral Fellowship (Ph.D.)

MECESUP Travel and Research Award

SBUR Travel Award

Prostate Cancer Training Award-Postdoctoral

Attraction and Integration Program for Advanced Human Capital in the Academia

Visiting Professor

Travel Award UNESCO/ICRO

Travel Award ICGEB

Travel Award UNESCO/ICRO

Article (66)

Correction (1)

Proyecto (12)

Consorcio Tecnológico IFAN=> Desarrollo Sinérgico de Ingredientes funcionales y Aditivos Naturales. P4. Desarrollo de un ingrediente funcional para el tratamiento del cáncer de próstata

PARACRINE EFFECT OF THE ENDOTHELIUM ON PROSTATE CANCER CELLS AND ITS ROLE DURING TUMOR PROGRESSION

Predictive test of prostate cancer progression based on stromal expression signature

ROL DE FRUCTOSA EN CÁNCER DE PRÓSTATA

Rol del Receptor de Andrógeno en Hiperplasia Prostática Benigna y su Utilidad como Nuevo Blanco Terapéutico en Hombres Mayores de 65 años con Falla a Tratamiento Médico

VEGF-A SIGNALING IN CARCINOMA-ASSOCIATED FIBROBLASTS=> ROLE IN REACTIVE STROMA GENERATION AND METASTATIC POTENTIAL"

Apoyo a la Formación de Redes Internacionales entre Centros de Investigación

Role of Fructose in Prostate Cancer

Busqueda del estado del arte para patentamiento/licenciamiento

ROLE OF ADRENAL ANDROGENS IN PROSTATE VASCULATURE

Clinical Relevance of Androgen Regulators in Castration Resistant Prostate Cancer

Androgen Effects on Human Prostate Endothelial Cells

Review (4)