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Luciano Esteban Ferrada Cofré

Investigador

Universidad de Concepción

Concepcion, Chile

Necroptosis and Ferroptosis pathways in cancer. Non-apoptotic cell death

Bioingeniero, UNIVERSIDAD DE CONCEPCION. Chile, 2014
ciencias basicas, UNIVERSIDAD DE CONCEPCION. Chile, 2011
Ciencias biológicas, Area biología celular y molecular, UNIVERSIDAD DE CONCEPCION. Chile, 2019

Investigador Full Time

Universidad de Concepción

Concepcion, Chile

2009 - 2018
Investigador Asociado Full Time

Centro de Microscopia Avanzada CMA BIOBIO

Concepcion, Chile

2018 - At present

Poster Presentation Award 2017

international society of antioxidants in nutrition and health

Francia, 2017

Poster Presentation Award 2017 during the 19th international congress “paris redox” 2017. Held at University Pierre &Marie Curie, Paris, France on june 26th and 27th 2017. International society of antioxidants, ISANH.
Expo posters alumnos y centros de investigacion I+D

UNIVERSIDAD DE CONCEPCION

Chile, 2016

Expo posters alumnos y centros de investigacion I+D. Año 2016 Universidad de concepción. Por obtener mención honrosa con el poster: Oxidation of vitamin C induces neuronal death and alterations in distribution of GLUT1/SVCT2 and mitochondrial size, en el festival de la ciencia, organizado por la dirección de postgrado de la Univresidad de Concepción.
CONCURSO DE INCENTIVO A ESTUDIANTES: PUBLICACIONES de 1er. AUTOR del PROYECTO MECESUP UCO 1311

UNIVERSIDAD DE CONCEPCION

Chile, 2015

CONCURSO DE INCENTIVO A ESTUDIANTES: PUBLICACIONES de 1er. AUTOR del PROYECTO MECESUP UCO 1311. Año 2015 Universidad de concepción. Reconocimiento a publicación como primer autor en revista ISI, por el artículo Dehydroascorbic Acid Promotes Cell Death in Neurons Under Oxidative Stress: a Protective Role for Astrocytes
Poster Followship

COLD SPRING HARBOR LABORATORY

China, 2018

Cold Spring Harbor Poster followship in Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease, Suzhou, CHINA, November 26-30, 2018
European Cell Death Organization Followship

DRESDEN UNIVERSITY OF TECHNOLOGY

Alemania, 2019

Beca de asistencia al 27 European Cell Death Organization (ECDO) 2019, en Dresden, Alemania. Por mi trabajo ede excelencia en muerte celular como científico joven.


Hexose Transporters in Cancer: From Multifunctionality to Diagnosis and Therapy Echeverria, Carolina; Nualart, Francisco; Ferrada, Luciano; Smith, Gary J.; Godoy, Alejandro S. Article ISI TRENDS IN ENDOCRINOLOGY AND METABOLISM (2021)
Two Distinct Faces of Vitamin C: AA vs. DHA Ferrada, Luciano; Magdalena, Rocio; Barahona, Maria Jose; Ramirez, Eder; Sanzana, Cristian; Gutierrez, Jose; Nualart, Francisco Article ISI ANTIOXIDANTS (2021)
Vitamin C deficient reduces proliferation in a human periventricular tumor stem cell-derived glioblastoma model Jara, Nery; Ramirez, Eder; Ferrada, Luciano; Salazar, Katterine; Espinoza, Francisca; Gonzalez-Chavarria, Ivan; Nualart, Francisco Article ISI JOURNAL OF CELLULAR PHYSIOLOGY (2021)
Vitamin C controls neuronal necroptosis under oxidative stress Ferrada L.; Barahona M.J.; Salazar K.; Vandenabeele P.; Nualart F. Article ISI SCOPUS (2020)
Vitamin C Recycling Regulates Neurite Growth in Neurospheres Differentiated In Vitro Espinoza, Francisca; Magdalena, Rocio; Saldivia, Natalia; Jara, Nery; Martinez, Fernando; Ferrada, Luciano; Salazar, Katterine; Avila, Felipe; Nualart, Francisco Article ISI ANTIOXIDANTS (2020)
Basal Sodium-Dependent Vitamin C Transporter 2 polarization in choroid plexus explant cells in normal or scorbutic conditions Ulloa V.; Saldivia N.; Ferrada L.; Salazar K.; Martinez F.; Silva-Alvarez, C; Magdalena, R; Oviedo, MJ; Montecinos H.; Torres-Vergara P.; Cifuentes M.; Nualart F. Article ISI SCOPUS SCIENTIFIC REPORTS (2019)
Metabolic control by dehydroascorbic acid: Questions and controversies in cancer cells Ferrada, Luciano; Salazar, Katterine; Nualart, Francisco Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2019)
SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies Salazar K.; Martínez F.; Pérez-Martín M.; Cifuentes M.; Trigueros L.; Ferrada L.; Espinoza F.; Saldivia N.; Bertinat R.; Forman K.; Oviedo M.J.; López-Gambero A.J.; Bonansco C.; Bongarzone E.R.; Nualart F. Article ISI SCOPUS MOLECULAR NEUROBIOLOGY (2017)
SVCT2 Is Expressed by Cerebellar Precursor Cells, Which Differentiate into Neurons in Response to Ascorbic Acid Karina Oyarce, Carmen Silva-Alvarez; Luciano Ferrada, Fernando Martínez; Katterine Salazar, Francisco Nualart Article Molecular Neurobiology (2017)
Dehydroascorbic acid promotes cell death in neurons under oxidative stress=> a protective role for astrocyte Andrea García-krauss , Luciano Ferrada ; allisson Astuya , Katterine Salazar ; Pedro Cisternas , Fernando Martinez; Eder Ramirez, Francisco Nualart Article Molecular Neurobiology (2015)
The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism Cisternas P.; Silva-Alvarez, C; Martinez F.; Fernandez, E; Ferrada, L.; Oyarce, K; Salazar, K.; Bolanos, JP; Nualart, F. Article ISI SCOPUS JOURNAL OF NEUROCHEMISTRY (2014)
Vitamin C Transporters, Recycling and the Bystander Effect in the Nervous System=> SVCT2 versus Gluts Francisco Nualart, Lauren Mack; Andrea García, Pedro Cisternas; Marjet Heitzer, Nery Jara; Fernando Martínez, Luciano Ferrada; Francisca Espinoza, Victor Baeza Article Stem Cell Research & Therapy (2014)


Dehydroascorbic acid promotes cell death in neurons under oxidative stress: a protective role for astrocytes Nualart, F.; Garcia-Krauss, A; Ferrada, L.; Salazar, K.; Cisternas P.; Martinez F. Abstract ISI JOURNAL OF NEUROCHEMISTRY (2015)


Vitamin C Transporter (SVCT2) Distribution in Developing and Adult Brains Ferrada, Luciano; Salazar, Katterine; Nualart, Francisco; Hamza, Amal BookSection (2017)


3D morphological characterization by confocal microscopy and super SIM resolution of the balloon-like morfology during neuronal necroptosis Ferrada, Luciano; Cerda, Gustavo; Nualart, Francisco ConferencePoster (2019)
Ferroptosis-resistant human glioblastoma cells are sensitized to ferroptosis by co-treatment with dehydroascorbic acid Ferrada, Luciano; Nualart, Francisco ConferencePoster (2019)
Human glioblastoma cells are sensitized to ferroptosis by co-treatment with dehydroascorbic acid and Erastin. Ferrada, Luciano; Ramirez, Eder; Nualart, Francisco ConferencePoster (2019)
Neuronal necroptosis is induced by vitamin C oxidation Ferrada, Luciano; Nualart, Francisco ConferencePoster (2018)
Vitamin C sensitizes neural cancer cells to ferroptosis Ferrada, Luciano; Nualart, Francisco ConferencePoster (2018)
Vitamin C and neuronal oxidative stress induce alterations in mitochondrial and cellular size, triggering neuronal death Ferrada, Luciano; Salazar, Katterine; Nualart, Francisco ConferencePoster (2017)
Oxidation of vitamin C induces neuronal death and alterations in distribution of GLUT1/SVCT2 and mitochondrial size. Ferrada, Luciano; Albarran, Camila; Salazar, Katterine; Nualart, Francisco ConferencePoster (2016)
Oxidation of vitamin C by oxidative stress produces neuronal death and redistribution of transporters GLUT1 and SVCT2 Ferrada, Luciano; Salazar, Katterine; Nualart, Francisco ConferencePoster (2015)