Man

Fernando Antonio Martinez Acuna

Assistant Professor

Universidad de Concepción

Concepción, Chile

Líneas de Investigación


Analysis of the location and function of proteins related to glucose and vitamin C transporter mechanisms in the central nervous system.

Educación

  •  Molecular and Cell Biology, UNIVERSIDAD DE CONCEPCION. Chile, 2012
  •  Biochemist, UNIVERSIDAD DE CONCEPCION. Chile, 2005
  •  Biochemistry, UNIVERSIDAD DE CONCEPCION. Chile, 2003

Experiencia Académica

  •   Assistant Professor Full Time

    UNIVERSIDAD DE CONCEPCION

    Biological Sciences

    Concepcion, Chile

    2014 - At present

Experiencia Profesional

  •   Thesis doctoral student Other

    Universidad de Concepción

    Chile

    2009 - 2009

  •   Technical for Fondecyt Grand Part Time

    Universidad de concepción

    Chile

    2010 - 2013

  •   Biochemist Part Time

    Universidad de Concepcion

    Chile

    2012 - 2013

  •   part time teacher Part Time

    Universidad de Concepción

    Chile

    2009 - 2009

  •   part time professor c100402 Part Time

    Universidad de Concepcion

    Chile

    2010 - 2010

  •   part time professor C111618 Part Time

    Universidad de Concepcion

    Chile

    2011 - 2011

  •   part time professor C120508/ C121741 Part Time

    Universidad de concepcion

    Chile

    2012 - 2012

Formación de Capital Humano


Undergraduate thesis .
Biology. University of Concepción
Conzuelo Soto
"Modification of the distribution of glucose transport proteins in the median eminence during different metabolic conditions"


Premios y Distinciones

  •   2009 Award for the best PhD presentation panel Society of Cell Biology Chile

    Sociedad de Biología Celular de Chile

    Chile, 2009

    Award for the best PhD presentation panel Society of Cell Biology Chile, HyClone-GenExpress prize.


 

Article (25)

Cytosolic phosphoenolpyruvate carboxykinase is expressed in α‐cells from human and murine pancreas

Westermeier, Francisco; Holyoak, Todd; Gatica, Rodrigo; Martínez, Fernando; Negrón, Marianne; Yáñez, Alejandro J.; Nahmias, Daniel; Nualart, Francisco; Burbulis, Ian; Bertinat, Romina

Article
JOURNAL OF CELLULAR PHYSIOLOGY  (2019)

The median eminence as the hypothalamic area involved in rapid transfer of glucose to the brain: functional and cellular mechanisms

Martínez, Fernando; Cifuentes, Manuel; Tapia, Juan Carlos; Nualart, Francisco

Article ISI SCOPUS
JOURNAL OF MOLECULAR MEDICINE-JMM  (2019)

Expression of a Novel Ciliary Protein, IIIG9, During the Differentiation and Maturation of Ependymal Cells

Cifuentes M, Baeza V, Arrabal PM, Visser R, Grondona JM, Saldivia N, Martínez F, Nualart F, Salazar K.

Article ISI
MOLECULAR NEUROBIOLOGY  (2018)

SVCT2 Is Expressed by Cerebellar Precursor Cells, Which Differentiate into Neurons in Response to Ascorbic Acid

Oyarce K, Silva-Alvarez C, Ferrada L, Martínez F, Salazar K, Nualart F.

Article ISI
MOLECULAR NEUROBIOLOGY  (2018)

Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior

Uranga, Romina María; Millán, Carola; Barahona, María José; Recabal, Antonia; Salgado, Magdiel; Martínez, Fernando; Ordenes, Patricio; Elizondo-Vega, Roberto; Sepúlveda, Fernando; Uribe, Elena; García-Robles, María de los Ángeles

Article ISI SCOPUS
SCIENTIFIC REPORTS  (2017)

Aging Selectively Modulates Vitamin C Transporter Expression Patterns in the Kidney

Forman K.; Martínez F.; Cifuentes M.; Bertinat R.; Salazar K.; Nualart F.

Article ISI SCOPUS
JOURNAL OF CELLULAR PHYSIOLOGY  (2017)

Apical Polarization of SVCT2 in Apical Radial Glial Cells and Progenitors During Brain Development

Silva-Álvarez C.; Salazar K.; Cisternas P.; Martínez F.; Liour S.; Jara N.; Bertinat R.; Nualart F.

Article ISI SCOPUS
MOLECULAR NEUROBIOLOGY  (2017)

SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies

Salazar K.; Martínez F.; Pérez-Martín M.; Cifuentes M.; Trigueros L.; Ferrada L.; Espinoza F.; Saldivia N.; Bertinat R.; Forman K.; Oviedo M.J.; López-Gambero A.J.; Bonansco C.; Bongarzone E.R.; Nualart F.

Article ISI SCOPUS
MOLECULAR NEUROBIOLOGY  (2017)

Cytoarchitecture, Proliferative Activity and Neuroblast Migration in the Subventricular Zone and Lateral Ventricle Extension of the Adult Guinea Pig Brain

Jara, N; Cifuentes, M; Martinez, F; Salazar, K; Nualart, F

Article ISI SCOPUS
STEM CELLS  (2016)

Dehydroascorbic Acid Promotes Cell Death in Neurons Under Oxidative Stress=> a Protective Role for Astrocytes.

García-Krauss A., Ferrada L.; Astuya A., Salazar K.; Cisternas P., Martínez F.; Ramirez E., Nualart F.

Article
MOLECULAR NEUROBIOLOGY  (2016)

SVCT2 Overexpression in Neuroblastoma Cells Induces Cellular Branching that is Associated with ERK Signaling

Salazar, K; Martinez, M; Ulloa, V; Bertinat, R; Martinez, F; Jara, N; Espinoza, F; Bongarzone, ER; Nualart, F

Article ISI
MOLECULAR NEUROBIOLOGY  (2016)

Dynamic Localization of Glucokinase and Its Regulatory Protein in Hypothalamic Tanycytes

SALGADO, MAGDIEL; Tarifeño-Saldivia, Estefanía; Ordenes, Patricio; Millán, Carola; Yañez, María José; Llanos, Paula; Villagra, Marcos; Elizondo?Vega, Roberto; Martínez, Fernando; Nualart, Francisco; Uribe, Elena; de los Angeles García-Robles, María; Chowen, Julie A.

Article ISI SCOPUS
PLOS ONE  (2014)

SVCT2 transporter expression is post-natally induced in cortical neurons and its function is regulated by its short isoform

Salazar K1, Cerda G, Martínez F, Sarmiento JM, González C, Rodríguez F, García-Robles M, Tapia JC, Cifuentes M, Nualart F.

Article ISI SCOPUS
JOURNAL OF NEUROCHEMISTRY  (2014)

The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism

Cisternas P.; Silva-Alvarez, C; Martinez F.; Fernandez, E; Ferrada, L.; Oyarce, K; Salazar, K.; Bolanos, JP; Nualart, F.

Article ISI SCOPUS
JOURNAL OF NEUROCHEMISTRY  (2014)

Vitamin C transporters, recycling and the Bystander effect in the nervous system: SVCT2 versus GLUTs

Nualart, F., Mack, L., García, A., Cisternas, P., Borgarzone, ER., Heitzer, M., Jara, N., Martínez, F., Espinoza, F., Ferrada, L., Baeza, V., Salazar, K.

Article ISI
Journal of Stem Cell Research and Therapy  (2014)

Clinical and experimental approaches to knee cartilage lesion repair and mesenchymal stem cell chondrocyte differentiation

Montoya, Fredy; Martínez, Fernando; García-Robles, María; Balmaceda-Aguilera, Carolina; Koch, Ximena; Rodríguez Federico; Silva-Alvarez, Carmen; Salazar, Katterine; Ulloa,Viviana; Nualart, Francisco

Article ISI SCIELO
BIOLOGICAL RESEARCH  (2013)

Human choroid plexus papilloma cells efficiently transport glucose and vitamin C

Ulloa V.; Garcia-Robles, M; Martinez F.; Salazar, K.; Reinicke K; Pérez F.; Godoy, DF; Godoy, AS; Nualart, F.

Article ISI SCOPUS
Journal of Neurochemistry  (2013)

MCT2 Expression and Lactate Influx in Anorexigenic and Orexigenic Neurons of the Arcuate Nucleus

Cortes-Campos, C; Elizondo, R; Carril C; Martinez F.; Boric K; Nualart, F.; Garcia-Robles, MA

Article ISI SCOPUS
PLOS ONE  (2013)

Typical and atypical stem cells in the brain, vitamin C effect and neuropathology

Nualart, Francisco; Salazar, Katterine; Oyarce, Karina; Cisternas, Pedro; Jara, Nery; Silva-Alvarez, Carmen; Pastor, Patricia; Martínez, Fernando; García, Andrea; García-Robles, María de los Ángeles; Tapia, Juan Carlos

Article ISI SCIELO SCOPUS
Biological Research  (2012)

Insulin Regulates GLUT1-Mediated Glucose Transport in MG-63 Human Osteosarcoma Cells

Cifuentes M.; García MA; Arrabal, PM; Martinez F.; Yanez, MJ; Jara, N; Weil B.; Domínguez D.; Medina RA.; Nualart, F.

Article ISI SCOPUS
Journal of Cellular Physiology  (2011)

Expression and localization of an agmatinase-like protein in the rat brain

Mella C.; Martinez F.; Garcia, MD; Nualart, F.; Castro, V; Bustos, P; Carvajal N.; Uribe, E

Article ISI SCOPUS
Histochemistry and Cell Biology  (2010)

Glial glucokinase expression in adult and post-natal development of the hypothalamic region

Millán C; Martinez F.; Cortes-Campos, C; Lizama I; Yanez, MJ; Llanos P.; Reinicke K; Rodriguez,F; Peruzzo, B; Nualart, F.; García MA

Article ISI SCOPUS
ASN NEURO  (2010)

Differential subcellular distribution of glucose transporters GLUT1-6 and GLUT9 in human cancer: Ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissues

Godoy A.; Ulloa V.; Rodriguez,F; Reinicke K; Yanez, AJ; Garcia, MD; Medina RA.; Carrasco M.; Barberis S.; Castro, T.; Martinez F.; Koch X; Vera, JC; Poblete, MT; Figueroa, CD; Peruzzo, B; Pérez F.; Nualart, F.

Article ISI SCOPUS
JOURNAL OF CELLULAR PHYSIOLOGY  (2006)

Iron affects the structure of cell membrane molecular models

Suwalsky, M; Martinez F.; Cardenas H.; Grzyb, J; Strzalka, K

Article ISI SCOPUS
CHEMISTRY AND PHYSICS OF LIPIDS  (2005)

Vitamin C uptake and recycling among normal and tumor cells from the central nervous system

Astuya A.; Caprile T.; Castro M.; Salazar, K.; Garcia, MD; Reinicke K; Rodriguez,F; Vera, JC; Millán C; Ulloa V.; Low M; Martinez F.; Nualart, F.

Article ISI SCOPUS
JOURNAL OF NEUROSCIENCE RESEARCH  (2005)

Abstract (1)

Dehydroascorbic acid promotes cell death in neurons under oxidative stress: a protective role for astrocytes

Nualart, F.; Garcia-Krauss, A; Ferrada, L.; Salazar, K.; Cisternas P.; Martinez F.

Abstract ISI
JOURNAL OF NEUROCHEMISTRY  (2015)

ConferencePoster (2)

Análisis espectral-confocal 3D y microdisección laser para definir la distribución de células gliales en el hipotálamo y la expresión de transportadores de glucosa, lactato y vitamina C

Martinez F.; Cortes-Campos, C; Elizondo, R; Osorio G.; Garcia-Robles, MA; Nualart, F.

ConferencePoster
 (2012)

Acute hyperglycemia induces structural changes in median eminence glial and vasculature

Jara, N; Rodriguez,F; Cisternas P.; Martinez F.; Nualart, F.

ConferencePoster
 (2010)

Proyecto (1)

“Median eminence, hypothalamic area involved in the rapid transfer of glucose to the brain: Functional and cellular mechanisms”

Martínez F

Proyecto
 (2016)

Review (1)

Brain Glucose-Sensing Mechanism and Energy Homeostasis

Lopez-Gambero, AJ; Martinez, F; Salazar, K; Cifuentes, M; Nualart, F

Review ISI SCOPUS
MOLECULAR NEUROBIOLOGY  (2019)

30
Fernando Martinez

Assistant Professor

Cell Biology

Universidad de Concepción

Concepción, Chile

14
María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

13
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

12
Katterine Salazar

Associate Professor

Cell Biology

University of Concepcion

Concepción, Chile

4
Elena Uribe

Associate Professor

Biochemistry and Molecular Biology

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

4
Juan Vera

Full professor

Pathophysiology

University of Concepcion

Concepción, Chile

4
Carola Millan

Profesor

de Ciencias

UNIVERSIDAD ADOLFO IBAÑEZ FACULTAD DE ARTES LIBERALES

Viña del Mar, Chile

4
Viviana Ulloa

Profesional Superior

Dirección de Estudios Estratégicos

Universidad de Concepción

Concepción, Chile

4
Romina Bertinat

Technician

Farmacología

Universidad de Concepcion

Concepción, Chile

3
Pedro Cisternas

Investigador Asociado

Biología Celular

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Nery Jara

Profesor Asistente

Departamento de Farmacología

Universidad de Concepción

Concepción, Chile

3
Teresa Caprile

Associate profesor

DPTO. BIOLOGIA CELULAR,

UNIVERSIDAD DE CONCEPCIÓN

Concepcion, Chile

3
Luciano Ferrada

Investigador

Biología celular

Universidad de Concepción

Concepcion, Chile

3
Allisson Astuya

profesor asociado

Departamento de Oceanografia de la Universidad de Concepción

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

3
Juan Tapia

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

2
Patricio Órdenes

Docente

Facultad de Ciencias de la Salud

Universidad San Sebastián

Concepción, Chile

2
Magdiel Salgado

INVESTIGADOR

BIOLOGIA CELULAR

Universidad de Concepción

CONCEPCION, Chile

2
Alejandro Yanez

Full professor

Faculty of Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2
KATHERINE FORMAN

Profesor Asociado

nutrition and dietetics

universidad de concepción

concepción, Chile

1
Karina Oyarce

Profesora asistente - Investigadora

Facultad de Medicina y Ciencia

Universidad San Sebastián, sede Tres Pascualas

Concepción, Chile

1
Maria Poblete

Profesor Auxiliar

Anatomia, Histologia y Patologia

Universidad Austral de Chile

Valdivia, Chile

1
Carlos Figueroa

Head

Anatomy, Histology and Pathology

Universidad Austral de Chile

Valdivia, Chile

1
Antonia Recabal

Profesor Asistente

Biología Celular

Universidad de Concepción

Concepción, Chile

1
Estefanía Tarifeño

Assistant professor

Bioquímica y Biología Molecular

Universidad de Concepción

Concepción, Chile

1
Jose Sarmiento

Assistant Professor

Physiology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
María José Barahona

Investigadora posdoctoral

Biología Celular

Universidad de Concepción

Concepción, Chile

1
Roberto Elizondo

Profesor Asistente

Departamento de Biología Celular

Universidad de Concepción

CONCEPCION, Chile

1
Víctor Castro

Profesor Asistente

Departamento de Biología

UNIVERSIDAD DE CHILE

Ñuñoa, Chile

1
Fredy Montoya

Upper extremity, In charge of shoulder and elbow surgery

- Hospital Traumatologico de Concepción

Concepción , Chile

1
Alejandro Godoy

Associate Professor

Centro de Biología Celular y Biomedicina

Universidad San Sebastián

Santiago, Chile

1
Francisca Espinoza

Investigadora postdoctoral

Facultad de Medicina

Universidad Católica de la Santisima Concepción

Concepción, Chile

1
Fernando Sepúlveda

Representante Legal

NeuroLabs

Talcahuano, Chile

1
Claudio Carril

Docente

Departamento de Ciencias Biológicas y Químicas

Universidad San Sebastián

Concepción, Chile

1
Marcela Low

Docente Investigador

Facultad de Medicina y Ciencia

Universidad San Sebastián

Valdivia, Chile