Man

Karina Alejandra Oyarce Merino

Profesora asistente - Investigadora

Universidad San Sebastián, sede Tres Pascualas

Concepción, Chile

Líneas de Investigación


Biologia celular; Neurobiologia ; Inmunología

Educación

  •  Doctorado en Cs. Biológicas, área Biología Celular y Molecular, UNIVERSIDAD DE CONCEPCION. Chile, 2015
  •  BIOINGENIERO, UNIVERSIDAD DE CONCEPCION. Chile, 2010
  •  Inmunoregulación, UNIVERSIDAD DE LOS ANDES. Chile, 2018

Experiencia Académica

  •   profesor asistente Full Time

    UNIVERSIDAD SAN SEBASTIAN

    Medicina y Ciencia

    concepción, Chile

    2017 - At present

Experiencia Profesional

  •   Estudiante de Pregrado/ Investigación

    Universidad de Concepción Facultad de Cs Químicas

    Chile

    2006 - 2009

  •   Alumna Tesista de Pregrado

    Universidad de Concepción Facultad de Cs. Biologicas

    Chile

    2009 - 2010

  •   Estudiante de Doctorado en Cs. Biologicas

    Universidad de Concepción Facultad de Cs. Biologicas

    Chile

    2010 - 2015

  •   Apoyo Técnico Proyecto FONDECYT de inicio N° 11130200

    Universidad San Sebastián, sede Tres Pascualas

    Chile

    2014 - 2016

  •   Co-investigadora Proyecto Interno USS ?Variación genética del receptor 2 de dopamina..."

    Universidad San Sebastián, sede Tres Pascualas

    Chile

    2016 - At present

  •   Docente Adjunto

    Universidad San Sebastián, sede Tres Pascualas

    Chile

    2014 - At present

  •   Docente Adjunto

    Universidad Nacional Andrés Bello

    Chile

    2014 - 2015

  •   Docente Adjunto

    Universidad de Concepción Facultad de Cs. Biologicas

    Chile

    2016 - 2016

Premios y Distinciones

  •   Premio Universidad de Concepción

    UNIVERSIDAD DE CONCEPCION

    Chile, 2010

    Premio a la excelencia académica, mejor alumna de promoción de Bioingeniería


 

Article (35)

Safety and efficacy of mesenchymal stromal cells mitochondria transplantation as a cell-free therapy for osteoarthritis

Garcia-Guerrero, Cynthia; Yanten-Fuentes, Liliana; Jeraldo, Nicole; Aros, Constanza; Troncoso, Francisca; Almarza, Gonzalo; Toledo, Jorge; Oyarce, Karina; Vernal, Rolando; Hidalgo, Yessia

Article ISI
JOURNAL OF TRANSLATIONAL MEDICINE  (2025)

Crosslinked oxidized-nanocellulose/chitosan hydrogels as a scaffold matrix for mesenchymal stem cell growth

Marino, Mayra A.; Oyarce, Karina; Paredes, Maria G.; Pavez, Paulina; Amoroso, Alejandro; Barjas, Gustavo Cabrera

Article ISI
CELLULOSE  (2024)

Regulatory T cells administration reduces anxiety-like behavior in mice submitted to chronic restraint stress

Cepeda, Yamila; Araneda, Matias; Oliveros, Patricia; Ordenes, Patricio; Oyarce, Karina

Article ISI
FRONTIERS IN CELLULAR NEUROSCIENCE  (2024)

Lactate: an alternative pathway for the immunosuppressive properties of mesenchymal stem/stromal cells

Oyarce, Karina; Bustos, Andres; Lagos, Raul; Abba Moussa, Daouda; Hidalgo-Fadic, Yessia

Article ISI
STEM CELL RESEARCH & THERAPY  (2023)

No association of the dopamine D2 receptor genetic bilocus score (rs1800497/rs1799732) on food addiction and food reinforcement in Chilean adults

Hidalgo Vira, Nicole; Oyarce, Karina

Article ISI
FRONTIERS IN BEHAVIORAL NEUROSCIENCE  (2023)

Neuroprotective and Neurotoxic Effects of Glial-Derived Exosomes

Oyarce, Karina; Cepeda, María Yamila; Lagos, Raul; Garrido, Camila

Article
Frontiers in Cellular Neuroscience  (2022)

Association of the dopamine D2 receptor rs1800497 polymorphism with food addiction, food reinforcement, and eating behavior in Chilean adults

Obregon, Ana M.; Oyarce, Karina; Valladares, Macarena; Pettinelli, Paulina

Article ISI
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY  (2021)

The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential

Oyarce, Karina

Article ISI
THERANOSTICS  (2021)

HIF1 alpha-dependent metabolic reprogramming governs mesenchymal stem/stromal cell immunoregulatory functions

Jose Paredes, Maria; Maria Vega-Letter, Ana; Oyarce, Karina

Article ISI
FASEB JOURNAL  (2020)

Inhibition of Hypothalamic MCT4 and MCT1-MCT4 Expressions Affects Food Intake and Alters Orexigenic and Anorexigenic Neuropeptide Expressions

Oyarce, Karina; SALGADO, MAGDIEL; Ordenes, Patricio; Lopez, Sergio; Pincheira, Roxana; Garcia-Robles, Maria Angeles

Article ISI SCOPUS
MOLECULAR NEUROBIOLOGY  (2020)

Glucose Increase DAGL alpha Levels in Tanycytes and Its Inhibition Alters Orexigenic and Anorexigenic Neuropeptides Expression in Response to Glucose

Palma-Chavez, Alejandra; Konar-Nie, Macarena; Ordenes, Patricio; Maurelia, Felipe; Oyarce, Karina; Lopez, Sergio; Steinberg, Ximena;

Article ISI SCOPUS
FRONTIERS IN ENDOCRINOLOGY  (2019)

Nutrient Sensing by Hypothalamic Tanycytes

Javier Elizondo-Vega, Roberto; Oyarce, Karina

Article ISI SCOPUS
FRONTIERS IN ENDOCRINOLOGY  (2019)

Mesenchymal stem cells and their immunosuppressive role in transplantation tolerance.

Contreras-Kallens, Pamina; Terraza, Claudia; Oyarce, Karina; Gajardo, Tania; Campos-Mora, Mauricio; Barroilhet, María Teresa; Álvarez, Carla; Fuentes, Ricardo; Figueroa, Fernando; Khoury, Maroun; Pino-Lagos, Karina

Article
Annals of the New York Academy of Sciences  (2018)

SVCT2 Is Expressed by Cerebellar Precursor Cells, Which Differentiate into Neurons in Response to Ascorbic Acid.

Oyarce, Karina; Silva-Alvarez, Carmen; Ferrada, Luciano; Martínez, Fernando; Salazar, Katterine; Nualart, Francisco

Article
Molecular neurobiology  (2018)

Vitamin C Fosters the Differentiation of Peripheral CD4 Foxp3 T Cells into CD4 Foxp3 Regulatory T Cells but Impairs Their Ability to Prolong Skin Allograft Survival.

Oyarce, Karina; Campos-Mora, Mauricio; Gajardo-Carrasco, Tania; Pino-Lagos, Karina

Article
Frontiers in immunology  (2018)

Association of the melanocortin 4 receptor gene rs17782313 polymorphism with rewarding value of food and eating behavior in Chilean children.

Obregón, A M; Oyarce, K; Santos, J L; Valladares, M; Goldfield, G

Article
Journal of physiology and biochemistry  (2017)

Association of the melanocortin 4 receptor gene rs17782313 polymorphism with rewarding value of food and eating behavior in Chilean children.

Obregón, A M; Oyarce, K; Santos, J L; Valladares, M; Goldfield, G

Article
Journal of physiology and biochemistry  (2017)

Mesenchymal stem cells and their immunosuppressive role in transplantation tolerance.

Contreras-Kallens, Pamina; Terraza, Claudia; Oyarce, Karina; Gajardo, Tania; Campos-Mora, Mauricio; Barroilhet, María Teresa; Álvarez, Carla; Fuentes, Ricardo; Figueroa, Fernando; Khoury, Maroun; Pino-Lagos, Karina

Article
Annals of the New York Academy of Sciences  (2017)

SVCT2 Is Expressed by Cerebellar Precursor Cells, Which Differentiate into Neurons in Response to Ascorbic Acid.

Oyarce, Karina; Silva-Alvarez, Carmen; Ferrada, Luciano; Martínez, Fernando; Salazar, Katterine; Nualart, Francisco

Article
Molecular neurobiology  (2017)

Inhibition of hypothalamic MCT1 expression increases food intake and alters orexigenic and anorexigenic neuropeptide expression

Jose Barahona, Maria; Ordenes, Patricio; SALGADO, MAGDIEL; Oyarce, Karina

Article ISI
SCIENTIFIC REPORTS  (2016)

Inhibition of hypothalamic MCT1 expression increases food intake and alters orexigenic and anorexigenic neuropeptide expression.

Elizondo-Vega, Roberto; Cortés-Campos, Christian; Barahona, María José; Carril, Claudio; Ordenes, Patricio; Salgado, Magdiel; Oyarce, Karina; García-Robles, María de Los Angeles

Article
Scientific reports  (2016)

Inhibition of hypothalamic MCT1 expression increases food intake and alters orexigenic and anorexigenic neuropeptide expression.

Elizondo-Vega, Roberto; Cortés-Campos, Christian; Barahona, María José; Carril, Claudio; Ordenes, Patricio; Salgado, Magdiel; Oyarce, Karina; García-Robles, María de Los Angeles

Article
Scientific reports  (2016)

The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism.

Cisternas, Pedro; Silva-Alvarez, Carmen; Martínez, Fernando; Fernandez, Emilio; Ferrada, Luciano; Oyarce, Karina; Salazar, Katterine; Bolaños, Juan P; Nualart, Francisco

Article
Journal of neurochemistry  (2014)

The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism.

Cisternas, Pedro; Silva-Alvarez, Carmen; Martínez, Fernando; Fernandez, Emilio; Ferrada, Luciano; Oyarce, Karina; Salazar, Katterine; Bolaños, Juan P; Nualart, Francisco

Article
Journal of neurochemistry  (2014)

Unconventional Neurogenic Niches and Neurogenesis Modulation by Vitamins.

Oyarce, Karina; Bongarzone, Ernesto R; Nualart, Francisco

Article
Journal of stem cell research & therapy  (2014)

Dynamic expression of the sodium-vitamin C co-transporters, SVCT1 and SVCT2, during perinatal kidney development.

Nualart, Francisco; Castro, Tamara; Low, Marcela; Henríquez, Juan Pablo; Oyarce, Karina; Cisternas, Pedro; García, Andrea; Yáñez, Alejandro J; Bertinat, Romina; Montecinos, Viviana P; García-Robles, María Angeles

Article
Histochemistry and cell biology  (2013)

Dynamic expression of the sodium-vitamin C co-transporters, SVCT1 and SVCT2, during perinatal kidney development.

Nualart, Francisco; Castro, Tamara; Low, Marcela; Henríquez, Juan Pablo; Oyarce, Karina; Cisternas, Pedro; García, Andrea; Yáñez, Alejandro J; Bertinat, Romina; Montecinos, Viviana P; García-Robles, María Angeles

Article
Histochemistry and cell biology  (2013)

SVCT2 vitamin C transporter expression in progenitor cells of the postnatal neurogenic niche.

Pastor, Patricia; Cisternas, Pedro; Salazar, Katterine; Silva-Alvarez, Carmen; Oyarce, Karina; Jara, Nery; Espinoza, Francisca; Martínez, Agustín D; Nualart, Francisco

Article
Frontiers in cellular neuroscience  (2013)

SVCT2 vitamin C transporter expression in progenitor cells of the postnatal neurogenic niche.

Pastor, Patricia; Cisternas, Pedro; Salazar, Katterine; Silva-Alvarez, Carmen; Oyarce, Karina; Jara, Nery; Espinoza, Francisca; Martínez, Agustín D; Nualart, Francisco

Article
Frontiers in cellular neuroscience  (2013)

Glucose transporter 1 and monocarboxylate transporters 1, 2, and 4 localization within the glial cells of shark blood-brain-barriers.

Balmaceda-Aguilera, Carolina; Cortés-Campos, Christian; Cifuentes, Manuel; Peruzzo, Bruno; Mack, Lauren; Tapia, Juan Carlos; Oyarce, Karina; García, María Angeles; Nualart, Francisco

Article
PloS one  (2012)

Glucose transporter 1 and monocarboxylate transporters 1, 2, and 4 localization within the glial cells of shark blood-brain-barriers.

Balmaceda-Aguilera, Carolina; Cortés-Campos, Christian; Cifuentes, Manuel; Peruzzo, Bruno; Mack, Lauren; Tapia, Juan Carlos; Oyarce, Karina; García, María Angeles; Nualart, Francisco

Article
PloS one  (2012)

Typical and atypical stem cells in the brain, vitamin C effect and neuropathology

Nualart, Francisco; Salazar, Katterine; Oyarce, Karina; Cisternas, Pedro; Jara, Nery; Silva-Alvarez, Carmen; Pastor, Patricia; Martinez, Fernando; García, Andrea; García-Robles, María de los Ángeles; et al.

Article ISI SCIELO SCOPUS
Biological Research  (2012)

Typical and atypical stem cells in the brain, vitamin C effect and neuropathology.

Nualart, Francisco; Salazar, Katterine; Oyarce, Karina; Cisternas, Pedro; Jara, Nery; Silva-Álvarez, Carmen; Pastor, Patricia; Martínez, Fernando; García, Andrea; García-Robles, María de los Ángeles; Tapia, Juan Carlos

Article
Biological research  (2012)

Human erythrocytes and molecular models of cell membranes are affected in vitro by Balbisia peduncularis (Amancay) extracts.

Suwalsky, Mario; Oyarce, Karina; Avello, Marcia; Villena, F; Sotomayor, Carlos P

Article
Chemico-biological interactions  (2009)

Human erythrocytes and molecular models of cell membranes are affected in vitro by Balbisia peduncularis (Amancay) extracts.

Suwalsky, Mario; Oyarce, Karina; Avello, Marcia; Villena, F; Sotomayor, Carlos P

Article
Chemico-biological interactions  (2009)

Proyecto (7)

nanoparticulas

Gonzalo Recio; Karina Oyarce

Proyecto
 (2022)

validacion de nuevos marcadores moleculares no invasivos con potencial diagnóstico para cáncer de colon en pacientes chilenos del gran concepción

Karina Oyarce

Proyecto
 (2022)

Immunomodulatory effect of vitamin D-treated Tregs on peripheral and central inflammation, on murine models of depression

Oyarce, Karina

Proyecto
 (2019)

Sensing de nutrientes a nivel cerebral como proceso clave para el desarrollo de nuevas terapias contra la obesidad

PCI (REDI170306)

Proyecto
2018-2019
Inv. Responsable

ROLE OF TANYCYTES IN FEEDING BEHAVIOUR

FONDECYT (1140677)

Proyecto
2014-2018
Personal técnico y/o de apoyo

GENETIC VARIATION OF THE DOPAMINE 2 RECEPTOR GENE AND THE MELANOCORTIN 4 RECEPTOR GENE=> ASSOCIATION WITH EATING BEHAVIOR

FONDECYT (11130200)

Proyecto
2013-2017
Personal técnico y/o de apoyo

CELLULAR BIOLOGY OF VITAMIN C TRANSPORTERS IN NORMAL AND CANCER STEM CELLS OF THE BRAIN

FONDECYT (1100396)

Proyecto
2010-2014
Tesista

Review (1)

Current Research on Molecular Biomarkers for Colorectal Cancer in Stool Samples

Ordenes, Patricio; Oyarce, Karina

Review ISI
BIOLOGY-BASEL  (2024)

3
Maroun Khoury

Professor

Faculty of Medicine

Universidad de Los Andes

santiago, Chile

1
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

5
María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

3
Claudia Altamirano

Profesor Titular

Facultad de Ingeniería

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

Valparaíso, Chile

1
Rolando Vernal

Profesor Titular

Departamento de Odontología Conservadora

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Rodrigo Segura

Full Professor, Institute Director

Instituto de Química y Bioquímica

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

1
Roxana Pincheira

Full Professor

Bioquímica y Biología Celular

Universidad de Concepcion

Concepción, Chile

1
Pedro Cisternas

Investigador Asociado

Biología Celular

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Fernando Martinez

Assistant Professor

Cell Biology

Universidad de Concepción

Concepción, Chile

1
Katterine Salazar

Associate Professor

Cell Biology

University of Concepcion

Concepción, Chile

1
Gustavo Cabrera

Profesor Asistente

Facultad de Ciencias para el Cuidado de la Salud

Universidad San Sebastián, Campus Las tres Pascualas

Concepción, Chile

1
Andrea del Campo

Profesor Asistente, Investigador Principal

Departamento de Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Ana Obregón

Docente Investigador

Facultad de Ciencias de la Salud

Universidad San Sebastian

Concepción , Chile

2
Macarena Valladares

Profesor asociado

Universidad de Las Américas

Santiago, Chile

1
Juan Tapia

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

5
Patricia Luz

Profesor asistente

Universidad de los Andes

Santiago , Chile

1
Ana Maria Vega

Investigador postdoctoral

Ingenieria Bioquimica

Potificia Universidad Catolica de Valpraiso

Valparaiso, Chile

1
Jorge Toledo

Investigador

Centro de Investigacion Clinica Avanzada CICA

Universidad de Chile, Hospital Clinico Universidad de Chile

Santiago, Chile

18
Karina Oyarce

Profesora asistente - Investigadora

Facultad de Medicina y Ciencia

Universidad San Sebastián, sede Tres Pascualas

Concepción, Chile

7
Roberto Elizondo

Profesor Asistente

Departamento de Biología Celular

Universidad de Concepción

CONCEPCION, Chile

1
ximena steinberg

Colaborador Docente

Bioquímica y Biologpia Molecular

Universidad de Concepción

Concepcion, Chile

1
Johanna Castaño

Docente Investigador

Ingeniería Quimica

Universidad de Concepción

Concepción, Chile

2
Antonia Recabal

Profesor Asistente

Biología Celular

Universidad de Concepción

Concepción, Chile

1
Aliosha Figueroa

Asistente de Investigación Senior

Centro de Medicina Intervencional de Precisión y Terapia Celular Avanzada (IMPACT)

Santiago, Chile

1
Nery Jara

Profesor Asistente

Departamento de Farmacología

Universidad de Concepción

Concepción, Chile

2
Yessia Hidalgo

Flow cytometry unit manager / Researcher

Centro de Investigación e Innovación Biomédica

Corporación IMPACT / Universidad de Los Andes

Santiago, Chile

1
José Concha

Assistant professor

Departamento de Ingeniería Civil y Ambiental

Universidad del Bío-Bío

Concepción, Chile

1
Charlotte Hill

Postdoctoral Fellow

CIIB

Universidad de Los Andes

Santiago, Chile

1
Pia Vidal

assistant professor

Universidad Católica de la Santisima Concepción

Concepcion, Chile

1
Magdiel Salgado

INVESTIGADOR

BIOLOGIA CELULAR

Universidad de Concepción

CONCEPCION, Chile

1
María José Barahona

Investigadora posdoctoral

Biología Celular

Universidad de Concepción

Concepción, Chile

1
Macarena Konar

Investigador

Universidad de Concepción

Concepción, Chile

2
Patricio Órdenes

Docente

Facultad de Ciencias de la Salud

Universidad San Sebastián

Concepción, Chile

1
RADMILA VELARDE

PostDoc

Escuela de Medicina

Universidad de Los Andes

Santiago, Chile

1
Nicole Jeraldo

1
Mauricio Sarabia

Profesor Asociado

Facultad de Ingeniería, Arquitectura y Diseño

Universidad San Sebastián

Santiago, Chile

1
Felipe Galvez

Estudiante Doctorado

Universidad de La Frontera

Temuco, Chile

1
Matías Araneda

Asistente de Investigación

Universidad San Sebastian

Concepción, Chile