Cerebrospinal fluid signaling. Developmental Biology. Subcommissural Organ. Axon guidance, Neurogenesis

TUTOR OF POSTGRADUATE STUDENTS

-Karen Stanic. PhD in cell biology, University of Concepción (2011-2017)
Title: "Study of the posterior commissure formation during Embryonic Development in Gallus Gallus".

-Melissa Gonzalez. Mgs in Biochemistry and Informatics. University iof Concepcion (2012-2015)
Title: "Variation of cerebrospinal fluid during early stages of embryonic development".

-America Vera. Mgs in Biochemistry and Bioinformatics. University of Concepción (2012-2015)
Title: "SCO-spondin contained in cerebrospinal fluid participates in early neurogenesis".

-Antonia Recabal. PhD in cell biology. University of Concepción (2015- in ejecution)
Title: "Effect of diet on hypothalamic neurogenesis"

-Sergio Lopez. Mgs in Biochemistry and Informatics. University of Concepción (2017-in ejecution)
Title:"Effect of diet in neurogenesis at the area postrema"

TUTOR OF UNDERGRADUATE STUDENTS

-Karen Stanich. Thesis of biochemistry. University of Concepción (2009-2011)
Title: "Expression of axonal guidance molecules in the diencephalic roof plate and its role in the formation of the posterior commissure".

-Melissa Gonzalez. Thesis of Bioingeniery.University of Concepción (2012-2014)
Title: "Standardization of two-dimensional electrophoresis of embryonic cerebrospinal fluid"

-Antonia Recabal.Thesis of Bioingeniery. University of Concepción (2013- 2014)
Title"Development of a methodology to establish the dynamics of embryonic cerebrospinal fluid"

- Carolina Cifuentes, Luisa Ríos and Manuel .Thesis of pedagogy in biology University of Concepción (2014-2015).
Title "Proposal for the preparation of pedagogical material for the unit "cell-organism integration"".

-Natalia Saldivia. Thesis of Bioingeniery. University of Concepción (2013- 2014).
"Expression of EphA4 and EphA2 during posterior commissure development".

-Israel Diaz and Natalia Sanchez. Thesis of pedagogy in biology.University of Concepción (2013-2014).
Title: "Methodological proposal for the unit organization and function of the nervous system ".

-Tatiana Alvarez Quintanillas. Thesis of pedagogy in biology, University of Concepción (2018).
Title: "How prepared are our students in preventing HIV virus infection?".

-Andrea Monsalvez Rojas and Javiera Reyes. Thesis of pedagogy in biology, University of Concepción (2018-2019).
Title: "Are the students of high school informed about ITS and contraception methods?.

A-CONGRESS OF THE SPECIALITY

-Stanic K., Gonzalez M., Montecinos H., Caprile T. (2014) Formation of the posterior commissure: a multi-step journey of commissural axons. Mechanism of Neuronal development. EMBO workshop. Kibbutz ein-Gedi, Israel. Marzo, 2014.

- Stanic K., Gonzalez M., Montecinos H., Caprile T. (2014) Axon guidance along caudal diencephalon: expression pattern of guidance cues towards the formation of the posterior commissure. 9th FENS forum of Neuroscience. Milán, Italia. Julio 2014

- González M.,Stanic K., Montecinos H., Caprile T. (2014) Chick embryonic cerebrospinal fluid analysis by 2D-PAGE.XXVIII Annual Meeting of the Chilean Society for Cell Biology, Puerto Varas. Octubre 2014.

- Stanic K., González M., Saldivia N., Montecinos H., Caprile T (2014). Expression pattern of guidance cues and extracellular matrix molecules along axonal navigation pathways in posterior commissure formation. XXVIII Annual Meeting of the Chilean Society for Cell Biology, Puerto Varas. Octubre 2014.

-Vera A., Recabal A., Riffo E., Montecinos H.,Caprile T. (2014) SCO-spondin from embryonic cerebrospinal fluid binds lipoproteins to regulate the early neurogénesis.XXVIII Annual Meeting of the Chilean Society for Cell Biology, Puerto Varas. Octubre 2014.

-Stanic K., Saldivia N., González M., Forstera B., Benitez JR.,Montecinos H., Caprile T.(2015) Expression pattern of extracellular matrix proteins in the prosomere I during posterior commissure development. Society for neuroscience, Chicago EEUU. Octubre 2015

-Recabal A., Saldivia N.,Montecinos H., Caprile T.(2015) Development of methodology for establishing the embryonic cerebrospinal fluid dynamics. XXIX Annual Meeting of the Chilean Society for Cell Biology, Chile, Puerto Varas. Octubre 2015

-Zelada D., Pinto C., Caprile T., Henríquez JP., Osses N. (2015) C-terminal tallo f BMP receptor type II translocates to the nuceus and inhibits morphological differentiation of motor neuron cells. XXIX Annual Meeting of the Chilean Society for Cell Biology, Chile, Puerto Varas. Octubre 2015

-Saldivia N., Stanic K., Recabal A., Montecinos H., Caprile T. (2015) Expression pattern of ephrin-a2 at early stages of posterior commissure formation. XXIX Annual Meeting of the Chilean Society for Cell Biology, Chile, Puerto Varas. Octubre 2015

-Stanic K., Forstera B., Benitez JR.,Montecinos H., Caprile T.(2016) Molecular expression n of guidance cues and extracellular matrix in the pretectal área during posterior commissure development. 10th FENS forum of Neuroscience. Copenhague, Dinamarca. Julio 2016

-Astuya A., Rodriguez F., Aballay-Gonzalez A., Ulloa V, Caprile T. (2016) In vitro approach for the study of toxic effects of harmful marine microalgae. The 17 International Conference of harmful Algae. Florianopolis, Brasil. Octubre 2016

- Recabal A, Fernández P, Caprile T, Sáez JC, García MA.(2017) Connexin 43 participates in the proliferation of Tanycytes in vitro. XXXI Annual Meeting of the Chilean Society for Cell Biology, Chile, Puerto Varas. Octubre 2017

-Recabal A; Elizondo-Vega R.,Palma A., Caprile T., Philippot C., Steinhauser C., Garcia-Robles MA. (2018) Role of connexin 43 in the formation of radial glia-like features in hypothalamic tanycytes: coupling and proliferation. 11th FENS forum of Neuroscience. Julio 2018, Berlin, Alemania.

B-OUTREACH ACTIVITIES

-Talk at Tomas Jefferson school for students of the last years of secundary education. Title "How to train your brain". Concepción, July 2014.

-Talk at Aurora de Chile school for students of the last years of secundary education. Title: "In search of the perfect synapse ". Chiguayante,october 2014

-Talk at Saint Johns school for college student. Títle “Navigating between synapses”. San Pedro de la Paz, October 2016.

-Talk in the course “Bioingenieria bajo la lupa”. Course organized by the faculty of biological sciences for students of the last years of secondary education. Title: Brain Hemispheres: Two Connected Worlds. December 2017

- Talk at Saint Johns school for college student. Títle "The brain, an organ in constant development"”. San Pedro de la Paz, mayo 2018.

-Talk in the course “Bioingenieria bajo la lupa”. Course organized by the faculty of biological sciences for students of the last years of secondary education. Title: Brain Hemispheres: Two Connected Worlds. December 2018

Talk at the Instituto de niñas school. Title "The brain in the sleeping world: why we need sleep?". March 2019

-Talk at the Santisima Trinidad school for student of the last years of secundary education. Title "The brain, an organ in constant development". April 2019.

-Reviewer in Explora congress, evaluating the scientific work of the differents schools of the Bio-Bio region. 2015-2018

C-OUTREACH AND EDUCATION GRANTS

-Education proyect Nº15-009 (2015-2017). Coautor. Title “Video platform as a complementary tool to face-to-face teaching to strengthen the teaching-learning process in subjects of Cell Biology and Histology".

-University of Concepcion outreach grant " Hundred years, hundred children, hundred microscopes". This project is financed by the University of Concepcion, and delivers folding microscopes (foldscopes) to 100 children of vulnerable rural schools, accompanied by lectures and delivery of biological matherial. The project ends with the visit of the children to the Concepcion Unversity and a prize to the best images taken with the microscope delivered. 2018-2019 (in phase final of ejecution)