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Gustavo Alonso Moraga Cid

Profesor Asistente

Universidad De Concepción

Concepción, Chile

Relación estructura función de canales ionicos activados por ligando. Farmacología estructural de canales ionicos activados por ligando.

Biología Celular y Molecular, UNIVERSIDAD DE CONCEPCION. Chile, 2009
Biologo Marino, UNIVERSIDAD DE CONCEPCION. Chile, 2002

Profesor Asistente Full Time

UNIVERSIDAD DE CONCEPCION

Facultad de Ciencias Biologícas

Concepcion, Chile

2016 - At present

Investigador Postdoctoral Full Time

Institute Pasteur

Paris, Francia

2010 - 2015
Investigador Postdoctoral Full Time

Centre Nationale de la Recherche Scientifique (CNRS)

Gif-sur-Yvette, Francia

2015 - 2016


Pentameric Ligand-Gated Ion Channels as Pharmacological Targets Against Chronic Pain. Lara CO, Burgos CF, Moraga-Cid G, Carrasco MA, Yévenes GE. Article ISI FRONTIERS IN PHARMACOLOGY (2020)
Altered glutaminase 1 activity during neurulation and its potential implications in neural tube defects Article ISI (2020)
Changes in PGC-1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model Article ISI WoS (2020)
Inhibition of the glycine receptor alpha 3 function by colchicine. Article WoS, ISI FRONTIERS IN PHARMACOLOGY (2020)
Modulation of glycine receptor single-channel conductance by intracellular phosphorylation San MartÃn V.P.; Lara C.O.; Marileo A.M.; Sazo A.; MuÃ±oz-Montesino C.; Fuentealba, J; Aguayo, L. G.; YÃ©venes G.E. Article ISI SCOPUS Scientific Reports (2020)
Therapeutic Use of Vitamin C in Cancer: Physiological Considerations. Article ISI FRONTIERS IN PHARMACOLOGY (2020)
Data on SVCT2 transporter expression and localization in cancer cell lines and tissues Inostroza, Eveling; Sotomayor, Kirsty; Maurin, Michelle; Sweet, Karen; Labrousse, Claire; Gatica, Marcell; Aylwin, Carlos E.; Maldonado, Mafalda; Delgado, Carolina; Madariaga, Jaime; et al. Article WOS-ESCI SCOPUS Data in Brief (2019)
Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer Peña E, Roa FJ, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Grecchi-Silva T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C, Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2019)
Inhibitory Actions of Tropeines on the alpha 3 Glycine Receptor Function San Martin, Victoria P.; Burgos, Carlos F.; Marileo, Ana M.; Sazo, Anggelo; Castro, Patricio A.; Aguayo, Luis G Article ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2019)
Inhibitory Actions of Tropeines on the α3 Glycine Receptor Function Article WoS, ISI FRONTIERS IN PHARMACOLOGY (2019)
Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors Article WoS, ISI (2019)
Plant growth promoting rhizobacteria with ACC deaminase activity isolated from Mediterranean dryland areas in Chile: Effects on early nodulation in alfalfa Cedeno-Garcia, GA; Gerding, M; Moraga, G; Oyarzua, P Article ISI SCIELO SCOPUS Chilena Journal of Agricultural Research (2018)
Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain Acu?a, Mario A.; Y?venes, Gonzalo E.; Ralvenius, William T.; Benke, Dietmar; Di Lio, Alessandra; Lara, Cesar O.; Mu?oz, Braulio; Corringer, Pierre-Jean; Zeilhofer, Hanns Ulrich Article ISI SCOPUS JOURNAL OF CLINICAL INVESTIGATION (2016)
Allosteric and hyperekplexic mutant phenotypes investigated on an alpha(1) glycine receptor transmembrane structure Moraga-Cid, G; Sauguet, L; Huon, C; Malherbe, L; Girard-Blanc, C; Petres, S; Murail, S; Taly, A; Baaden, M; Delarue, M; et al. Article ISI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Control of Ethanol Sensitivity of the Glycine Receptor alpha 3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain Sanchez A.; Burgos, C. F.; Moraga-Cid, G; Harvey R.J.; Aguayo, L. G. Article ISI SCOPUS JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Intermediate closed state for glycine receptor function revealed by cysteine cross-linking Prevost, MS; Moraga-Cid, G; Van Renterghem, C; Edelstein, SJ; Changeux, JP; Corringer, PJ Article ISI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels Sauguet, L; Poitevin, F; Murail, S; Van Renterghem, C; Moraga-Cid, G; Malherbe, L; Thompson, AW; Koehl, P; Corringer, PJ; Baaden, M; et al. Article ISI EMBO JOURNAL (2013)
A Single Phenylalanine Residue in the Main Intracellular Loop of alpha 1 gamma-Aminobutyric Acid Type A and Glycine Receptors Influences Their Sensitivity to Propofol Moraga-Cid, G; Yevenes, GE; Schmalzing, G; Peoples, RW; Aguayo, LG Article ISI SCOPUS Anesthesiology (2011)
Activated G Protein alpha(s) Subunits Increase the Ethanol Sensitivity of Human Glycine Receptors Yevenes, GE; Moraga-Cid, G; Romo, X.; Aguayo, LG Article ISI SCOPUS Journal of Pharmacology and Experimental Therapeutics (2011)
Allosteric Modulation of Retinal GABA Receptors by Ascorbic Acid Calero, CI; Vickers E.; Cid, GM; Aguayo, LG; von Gersdorff H.; Calvo, DJ Article ISI SCOPUS Journal of Neuroscience (2011)
Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family Duret, G; Van Renterghem, C; Weng, Y.; Prevost, M; Huon, C; Sonner, JM; Corringer, PJ Article ISI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Potentiation and inhibition of glycine receptors by tutin Fuentealba, J; Muñoz B.; Yevenes, G; Moraga-Cid, G; Guzman, L; Aguayo, L. G.; Pérez, C.; Rigo J.M. Article ISI SCOPUS Neuropharmacology (2011)
Canonical Wnt3a Modulates Intracellular Calcium and Enhances Excitatory Neurotransmission in Hippocampal Neurons Avila, ME; Sepulveda, FJ; Burgos, CF; Moraga-Cid, G; Parodi, J; Moon RT.; Aguayo, LG; Opazo C.; De Ferrari, GV Article ISI SCOPUS Journal of Biological Chemistry (2010)
Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Selective G beta gamma Modulation Yevenes, GE; Moraga-Cid, G; Avila, A; Guzman, L; Figueroa, M.; Peoples, RW; Aguayo, LG Article ISI SCOPUS Journal of Biological Chemistry (2010)
Blockade of Ethanol-Induced Potentiation of Glycine Receptors by a Peptide That Interferes with GB gamma Binding Guzman, L; Moraga-Cid, G; Avila, A; Figueroa, M.; Yevenes, GE; Fuentealba, J; Aguayo, LG Article ISI SCOPUS JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
A selective G beta gamma-linked intracellular mechanism for modulation of a ligand-gated ion channel by ethanol Yevenes, GE; Moraga-Cid, G; Peoples, RW; Schmalzing, G; Aguayo, LG Article ISI SCOPUS PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mechanistic insights and functional determinants of the transport cycle of the ascorbic acid transporter SVCT2 Godoy A.; Ormazabal, V; Moraga-Cid, G; Sotomayor P.; Barra V; Vásquez O.; Montecinos, V.; Mardones L.; Guzmán C; Villagrán M.; et al. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Effects of pulp and paper mill discharges on caged rainbow trout (Oncorhynchus mykiss): Biomarker responses along a pollution gradient in the Biobio River, Chile Orrego R.; Burgos A.; Moraga-Cid, G; Inzunza, B; GONZALEZ, M; Valenzuela A.; Barra, R; Gavilan, JE Article ISI ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2006)
Molecular determinants for G protein beta gamma modulation of ionotropic glycine receptors Yevenes, GE; Moraga-Cid, G; Guzman, L; Haeger, S; Oliveira L.; Olate, J; Schmalzing, G; Aguayo, LG Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
An RNA vaccine based on recombinant semliki forest virus particles expressing the Cu,Zn superoxide dismutase protein of Brucella abortus induces protective immunity in BALB/c mice Onate, AA; Donoso G.; Moraga-Cid, G; Folch H.; Cespedes, S; Andrews E. Article ISI SCOPUS INFECTION AND IMMUNITY (2005)
Reproductive, physiological, and biochemical responses in juvenile female rainbow trout (Oncorhynchus mykiss) exposed to sediment from pulp and paper mill industrial discharge areas Orrego R.; Moraga-Cid, G; GONZALEZ, M; Barra, R; Valenzuela A.; Burgos A.; Gavilan, JE Article ISI SCOPUS ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2005)
Intraspleen delivery of a DNA vaccine coding for superoxide dismutase (SOD) of Brucella abortus induces SOD-specific CD4(+) and CD8(+) T cells Munoz-Montesino, C; Andrews E.; Rivers, R; Gonzalez-Smith, A; Moraga-Cid, G; Folch H.; Cespedes, S; Onate, AA Article ISI SCOPUS INFECTION AND IMMUNITY (2004)


CONTROL OF GAIN AND LOSS OF ETHANOL ALLOSTERIC POTENTIATION BY RESIDUES WITHIN THE GLYCINE RECEPTOR Aguayo, LG; Yevenes, GE; Moraga-Cid, G; Avila, A; Guzman, L; Figueroa, M.; Peoples, RW Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2010)
Understanding the importance of intracellular regions in the glycine receptor for ethanol actions Aguayo, LG; Yevenes, G; Moraga-Cid, G; Peoples, RW; Schmalzing, G Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2008)
G protein-dependent mechanisms for ethanol actions on glycine activated ion channels Aguayo, LG; Yevenes, G; Moraga-Cid, G; Schmalzing, G Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2007)
Differential regulation of ethanol- and general anesthetic-induced modulation by the intracellular loop of glycine receptor. Aguayo, LG; Yevenes, G; Moraga-Cid, G; Peoples, RW; Schmalzing, G Abstract ISI ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2006)


Developing a touchscreen-based domotic tool for users with motor disabilities Cofré J.P.; Moraga, G; Rusu, C; Mercado, I.; Inostroza R.; Jiménez C ConferencePaper SCOPUS Proceedings of the 9th International Conference on Information Technology, ITNG 2012 (2012)


Análisis de mutaciones causantes de hiperekplexia usando la estructura atómica del receptor de glycina humano. ConferencePoster (2016)
Molecular mechanism underlying the functional inhibition of the glycine receptor 3 subunit by PKA-mediated phosphorylation San Martin V, Muñoz B, Lara CO, Moraga-Cid G, Yévenes G ConferencePoster (2016)
• Examination of the hiperekplexia phenotype in the x-ray structure of the human glycine receptor 1 subunit Moraga-Cid G, Sauguet L, Huon C, Malherbe L, Girard-Blanc C, Petres S, Murail S, Taly A, Baaden M, Delarue M, Corringer PJ ConferencePoster (2016)
• Modulación conformación-especifica de receptores inhibitorios: Una nueva aproximación hacia nuevos fármacos analgésicos Yévenes, G.E.; Acuña, M.; Lara, C.O.; Muñoz, B.; Burgos, C.F.; Ralvenius, W.; Di Lio, A.; Moraga-Cid, G.; Corringer, P.J., Zeilhofer, H.U ConferencePoster (2016)
• Molecular sites for the modulation of glycine receptor by the analgesic alkaloid gelsemine Marileo A, Burgos CF, Lara CO, San Martin V, Moraga-Cid G, Yevenes G ConferencePoster (2016)


Targeting glycine receptors for the treatment of chronic pain, hyperekplexia and anxiety: development of novel modulators based on recent structural and pharmacological insights Proyecto (2017)
Aβ assemblies propagation and cell damage Rivas, Coralia Proyecto (2017)
Deciphering the functional and structural properties of the large intracellular domain of the pentameric ligand gated receptors”. Proyecto (2016)
Molecular pharmacology of ethanol action on pentameric channel receptors based on their 3D structures: an electrophysiological study Proyecto (2012)


Pentameric Ligand-Gated Ion Channels as Pharmacological Targets Against Chronic Pain Lara C.O.; Carrasco M.A. Review ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2020)
Therapeutic Use of Vitamin C in Cancer: Physiological Considerations Escobar-AcuÃ±a K.; Rivas C.I. Review ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2020)
Potentiation of Gamma Aminobutyric Acid Receptors (GABA(A)R) by Ethanol How Are Inhibitory Receptors Affected? Aguayo, L. G. Review ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2016)

Ariel Valenzuela

Prof. Asistente

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

CORALIA RIVAS

Associated Professor

Pathophysiology

UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

Ricardo Barra

Profesor Titular

Sistemas Acuáticos

Facultad de Ciencias Ambientales/Centro EULA Chile

Concepción, Chile

Hugo Folch

Professor

Immunology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Juan Carcamo

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

Juan Vera

Full professor

Pathophysiology

University of Concepcion

Concepción, Chile

JORGE FUENTEALBA

Dean

Physiology

UNIVERISDAD DE CONCEPCION

Concepcion, Chile

Felipe Zuñiga

Profesor Asistente

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Maximiliano Figueroa

Profesor Asociado

Bioquímica y Biología Molecular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Sergio Onate

Associate Professor

Medical Specialties

UNIVERSIDAD DE CONCEPCION, DEPARTAMENTO FISIOPATOLOGIA

concepcion, Chile

Macarena Gerding

Profesor Asociado

Producción Vegetal

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE AGRONOMÍA

Chillán, Chile

Giancarlo De Ferrari

Full Professor

Biological Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Lorena Mardones

ASSOCIATED PROFESSOR

BASIC SCIENCES AND MORPHOLOGY

UNIVERSIDAD CATOLICA DE LA SANTISIMA CONCEPCION

CONCEPCION, Chile

Gabriel Donoso

Investigador

Producción Vegetal

Instituto de Investigaciones Agropecuarias

Chillán, Chile

Alejandro Godoy

Associate Professor

Centro de Biología Celular y Biomedicina

Universidad San Sebastián

Santiago, Chile

Viviana Montecinos

Assistant Professor

Hematology Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Alejandro Reyes

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

Claudia Perez

Academic

Botany

University of Concepción

Concepción, Chile

JOSE GUZMAN

Full professor

Fisiología

Universidad de Concepción

Concepcion, Chile

Gonzalo Yévenes

Associate Professor

Universidad de Concepcion

Concepcion, Chile

CAROLINA DELGADO

Encargado de proyectos de desarrollo de Unidad de Anatomía Patológica

CR Diagnóstico Terapéutico

Hospital Regional Concepción HGGB

Concepcion, Chile

Fernando Sepúlveda

Representante Legal

NeuroLabs

Talcahuano, Chile

Patricio Castro

profesor asistente

fisiologia

UNIVERSIDAD Concepcion

concepcion, Chile

Gustavo Moraga

Assistant Professor

UNIVERSIDAD DE CONCEPCION

Chile

Monica Carrasco

Profesor Asociado

Escuela de Medicina

UNIVERSIDAD DE TALCA

Talca, Chile

MAFALDA MALDONADO

PROFESOR ASOCIADO

Fisopatología

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

Carola Muñoz

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Andrea Sanchez

Profesor Asociado

Bioquímica Clínica e Inmunología

UNIVERSIDAD DE CONCEPCION

concepcion, Chile

Francisco Roa

Profesor Asistente

Fisiopatología, Facultad de Ciencias Biológicas

Universidad de Concepción

Concepción, Chile

Carlos Burgos

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

Pía Oyarzua

Jefe de Laboratorio

Producción Vegetal

Universidad de Concepción

Chillán, Chile

Paula Sotomayor

Investigador

Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

Valeska Ormazabal

Profesor asistente

Farmacología

Universidad de Concepción

Concepción, Chile

Maximiliano Figueroa

Assstant Professor

Universidad de Concepción

Concepción, Chile

Marcell Gatica

Profesora asistente

Bioquímica y Biología Molecular

Universidad de Concepción

Concepción, Chile

Miguel Ávila

Docente/Investigador

Universidad de las Américas

Santiago, Chile

Gustavo Moraga

Profesor Asistente

Departamento de Fisiología

Universidad De Concepción

Concepción, Chile

Luis Orrego

Associate Professor / Asociate Researcher

Faculty of Marine Science and Biological Resources

University of Antofagasta

Antofagasta, Chile

Loreto San Martín

Abed Burgos

Docente part-time

Facultad de Ciencias

Universidad Católica de la Santísima Concepción

Concepción, Chile

MARCELO VILLAGRAN

Profesor asociado

Departamento de Ciencias Básicas

Universidad Catolica de la Santísima Concepción

Concepcion, Chile

mauricio gonzalez

phd

fisiopatologia

universidad de concepción

concepcion, Chile

Jessica Panes

Alumna de Doctorado

Fisiología

Universidad de Concepción

Concepcion, Chile

Victoria San Martín

Tesista Doctorado

Fisiologia

Universidad de Concepción

Concepción, Chile

Ana Marileo

Tesista de Doctorado

De Fisiología

Universidad de Concepción

Concepción, Chile

BARBARA INZUNZA

profesor asistente

Biología Celular

Universidad de Concepción

Concepción, Chile

Gustavo Alonso Moraga Cid

Líneas de Investigación

Educación

Biología Celular y Molecular, UNIVERSIDAD DE CONCEPCION. Chile, 2009

Biologo Marino, UNIVERSIDAD DE CONCEPCION. Chile, 2002

Experiencia Académica

Profesor Asistente Full Time

Experiencia Profesional

Investigador Postdoctoral Full Time

Investigador Postdoctoral Full Time

Article (32)

Abstract (4)

ConferencePaper (1)

ConferencePoster (5)

Proyecto (4)

Review (3)