Man

Maximiliano Francisco Figueroa Yévenes

Profesor Asociado

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Líneas de Investigación


Diseño y caracterización de proteínas y péptidos artificiales; producción de proteínas recombinantes; estudios espectroscópicos de proteínas para deterninación y caracterización estructural; estudios de interacción proteína-proteína y proteína-ligand

Educación

  •  Biología celular y molecular, UNIVERSIDAD DE CONCEPCION. Chile, 2010
  •  Bioquímica, UNIVERSIDAD DE CHILE. Chile, 2005

Experiencia Académica

  •   Investigador Postdoctoral Full Time

    Université de Liège

    Bélgica

    2010 - 2015

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE CONCEPCION

    Chile

    2016 - At present

  •   Profesor Invitado Other

    Université de Liège

    Bélgica

    2019 - 2020

Experiencia Profesional

  •   Investigador Full Time

    Universidad de Liège

    Bélgica

    2010 - 2015

Premios y Distinciones

  •   Catedrático del Mundo Francófono

    Real Academia de Ciencias, Letras y Bellas Artes

    Bélgica, 2019

    Primer extranjero en obtener la distinción de Catedrático del mundo francófono. Consiste en el honor de ser un extranjero francoparlante con un CV disitnguido en el área de las ciencias. Fui invitado a permanecer 1 año en Bélgica y participar de todas las actividades de la Real Academia Belga, y en la organización de eventos de difusión


 

Article (38)

Effect of temperature and nucleotide on the binding of BiP chaperone to a protein substrate

Rivera, Maira; Burgos-Bravo, Francesca; Engelberger, Felipe; Asor, Roi; Lagos-Espinoza, Miguel I. A.; Figueroa, Maximiliano; Kukura, Philipp; Ramirez-Sarmiento, Cesar A.; Baez, Mauricio; Smith, Steven B.; Wilson, Christian A. M.

Article ISI
PROTEIN SCIENCE  (2023)

New Insights into the Determinants of Specificity in Human Type I Arginase: Generation of a Mutant That Is Only Active with Agmatine as Substrate

Orellana, Maria-Soledad; Jana, Gonzalo A.; Figueroa, Maximiliano; Martinez-Oyanedel, Jose; Medina, Fabiola E.; Tarifeno-Saldivia, Estefania; Gatica, Marcell; Garcia-Robles, Maria Angeles; Carvajal, Nelson; Uribe, Elena

Article ISI
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES  (2022)

Crystal Structure of Escherichia coli Agmatinase: Catalytic Mechanism and Residues Relevant for Substrate Specificity

Maturana, Pablo; Orellana, Maria S.; Herrera, Sixto M.; Martinez, Ignacio; Figueroa, Maximiliano; Martinez-Oyanedel, Jose; Castro-Fernandez, Victor; Uribe, Elena

Article ISI
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES  (2021)

Biosynthesis and characterization of a recombinant eukaryotic allophycocyanin using prokaryotic accessory enzymes

Dagnino-Leone, Jorge; Figueroa, Maximiliano; Uribe, Elena; Victoria Hinrichs, Maria; Ortiz-Lopez, Diego; Martinez-Oyanedel, Jose; Bunster, Marta

Article ISI SCOPUS
MICROBIOLOGYOPEN  (2020)

Gabapentin Inhibits Multiple Steps in the Amyloid Beta Toxicity Cascade

Gonzalez-Sanmiguel, Juliana; Burgos, Carlos F.; Bascunan, Denisse; Fernandez-Perez, Eduardo J.; Riffo-Lepe, Nicolas; Boopathi, Subramanian; Fernandez-Perez, Arturo; Bobadilla-Azocar, Catalina; Gonzalez, Wendy; Figueroa, Maximiliano; Vicente, Benjamin; Aguayo, Luis G.

Article ISI
ACS Chemical Neuroscience  (2020)

Insights into the Mn2+ Binding Site in the Agmatinase-Like Protein (ALP): A Critical Enzyme for the Regulation of Agmatine Levels in Mammals

Reyes, María-Belen; Martínez-Oyanedel, José; Navarrete, Camila; Mardones, Erika; Martínez, Ignacio; Salas, Mónica; López, Vasthi; García-Robles, María; Tarifeño-Saldivia, Estefania; Figueroa, Maximiliano; García, David; Uribe, Elena

Article ISI, WOS
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES  (2020)

Insights on the participation of Glu256 and Asp204 in the oligomeric structure and cooperative effects of human arginase type I

Lobos, Marcela; Figueroa, Maximiliano; Martínez-Oyanedel, José; López, Vasthi; García-Robles, María de los Ángeles; Tarifeño-Saldivia, Estefanía; Carvajal, Nelson; Uribe, Elena

Article WOS, ISI
Journal of Structural Biology  (2020)

Metabolic strategies for the degradation of the neuromodulator agmatine in mammals

Benitez, Jose; Garcia, David; Romero, Nicol; Gonzalez, Arlette; Martinez-Oyanedel, Jose; Figueroa, Maximiliano; Salas, Monica; Lopez, Vasthi; Garcia-Robles, Maria; Dodd, Peter R.; Schenk, Gerhard; Carvajal, Nelson; Uribe, Elena

Article ISI SCOPUS
METABOLISM-CLINICAL AND EXPERIMENTAL  (2018)

Metabolic strategies for the degradation of the neuromodulator agmatine in mammals.

Benítez, José; García, David; Romero, Nicol; González, Arlette; Martínez-Oyanedel, José; Figueroa, Maximiliano; Salas, Mónica; López, Vasthi; García-Robles, María; Dodd, Peter R; Schenk, Gerhard; Carvajal, Nelson; Uribe, Elena

Article
Metabolism=> clinical and experimental  (2018)

The gamma(33) subunit of R-phycoerythrin from Gracilaria chilensis has a typical double linked phycourobilin similar to y subunit

Vasquez-Suarez, Aleikar; Lobos-Gonzalez, Francisco; Cronshaw, Andrew; Sepulveda-Ugarte, Jose; Figueroa, Maximiliano; Dagnino-Leone, Jorge; Bunster, Marta; Martinez-Oyanedel, Jose

Article ISI SCOPUS
PLOS ONE  (2018)

The γ33 subunit of R-phycoerythrin from Gracilaria chilensis has a typical double linked phycourobilin similar to γ subunit.

Vásquez-Suárez, Aleikar; Lobos-González, Francisco; Cronshaw, Andrew; Sepúlveda-Ugarte, José; Figueroa, Maximiliano; Dagnino-Leone, Jorge; Bunster, Marta; Martínez-Oyanedel, José

Article
PloS one  (2018)

Designing artificial TIM-barrel proteins from scratch=> the Octarellin model

Martina, C.E.; Figueroa, M.; Gutierrez-Maroto, C.; Moretti, R.; Combs, S.; Meiler, J.; Van de Weerdt, C.; Matagne, A.

Article
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS  (2017)

Structural models of the different trimers present in the core of phycobilisomes from Gracilaria chilensis based on crystal structures and sequences.

Dagnino-Leone, Jorge; Figueroa, Maximiliano; Mella, Claudia; Vorphal, María Alejandra; Kerff, Frédéric; Vásquez, Aleikar José; Bunster, Marta; Martínez-Oyanedel, José

Article
PloS one  (2017)

Biophysical characterization data of the artificial protein Octarellin V.1 and binding test with its X-ray helpers

Figueroa, Maximiliano; Vandenameele, Julie; Goormaghtigh, Erik; Valerio-Lepiniec, Marie; Minard, Philippe; Matagne, André; Van de Weerdt, Cécile

Article
Data in Brief  (2016)

Biophysical characterization data of the artificial protein Octarellin V.1 and binding test with its X-ray helpers.

Figueroa, Maximiliano; Vandenameele, Julie; Goormaghtigh, Erik; Valerio-Lepiniec, Marie; Minard, Philippe; Matagne, André; Van de Weerdt, Cécile

Article
Data in brief  (2016)

The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.

Figueroa, Maximiliano; Sleutel, Mike; Vandevenne, Marylene; Parvizi, Gregory; Attout, Sophie; Jacquin, Olivier; Vandenameele, Julie; Fischer, Axel W; Damblon, Christian; Goormaghtigh, Erik; Valerio-Lepiniec, Marie; Urvoas, Agathe; Durand, Dominique; Pardon, Els; Steyaert, Jan; Minard, Philippe; Maes, Dominique; Meiler, Jens; Matagne, André; Martial, Joseph A; Van de Weerdt, Cécile

Article
Journal of structural biology  (2016)

A novel secondary structure element assembly protocol for the design of artificial (ba)8-barrel proteins using ROSETTA

Martina, Cristina Elisa; Combs, Steven; Moretti, Rocco; Figueroa, Maximiliano; Van de Weerdt, Cécile; Matagne, André; Meiler, Jens

Article
PROTEIN SCIENCE  (2015)

Aided-Crystallization of the artificial protein Octarellin V.1 by alpha-Reps and nanobodies

Figueroa, Maximiliano; Sleutel, Mike; Matagne, André; Damblon, Christian; Pardon, Els; Valerio-Lepiniec, Marielle; Minard, Philippe; Martial, Joseph; Van de Weerdt, Cécile

Article
PROTEIN SCIENCE  (2015)

Octarellin VI: Using Rosetta to Design a Putative Artificial (beta/alpha)(8) Protein

Figueroa, Maximiliano; Oliveira, Nicolas; Lejeune, Annabelle; Kaufmann, Kristian W.; Dorr, Brent M.; Matagne, Andre; Martial, Joseph A.; Meiler, Jens; Van de Weerdt, Cecile

Article ISI
PLOS ONE  (2013)

Octarellin VI: using rosetta to design a putative artificial (β/α)8 protein.

Figueroa, Maximiliano; Oliveira, Nicolas; Lejeune, Annabelle; Kaufmann, Kristian W; Dorr, Brent M; Matagne, André; Martial, Joseph A; Meiler, Jens; Van de Weerdt, Cécile

Article
PloS one  (2013)

The Artificial Protein Octarellin V.1 is soluble, themrostable and monomeric but apparently differs with the in silico model

Figueroa, Maximiliano; Jacquin, Olivier; Matagne, André; Damblon, Christian; Goormaghtigh, Erik; Valerio-Lepiniec, Marielle; Minard, Philippe; Martial, Joseph; Van de Weerdt, Cécile

Article
PROTEIN SCIENCE  (2013)

In silico model of an antenna of a phycobilisome and energy transfer rates determination by theoretical Forster approach

Figueroa, M; Martinez-Oyanedel, J; Matamala A.R.; Dagnino-Leone, J; Mella C.; Fritz R.; Sepulveda-Ugarte J.; Bunster, M

Article ISI SCOPUS
Protein Science  (2012)

In silico model of an antenna of a phycobilisome and energy transfer rates determination by theoretical Forster approach

Figueroa M.; Martinez-Oyanedel J.; Matamala A.R.; Dagnino-Leone J.; Mella C.; Fritz R.; Sepulveda-Ugarte J.; Bunster M.

Article
PROTEIN SCIENCE  (2012)

The Basic Property of Lys385 Is Important for Potentiation of the Human alpha 1 Glycine Receptor by Ethanol

Castro P.A.; Figueroa M.; Yevenes G.E.; San Martin L.S.; Aguayo L.G.

Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS  (2012)

The Basic Property of Lys385 Is Important for Potentiation of the Human alpha 1 Glycine Receptor by Ethanol

Castro P.A.; Figueroa, M; Yévenes G.E.; San Martin, L. S.; Aguayo, L. G.

Article ISI SCOPUS
Journal of Pharmacology and Experimental Therapeutics  (2012)

CONTROL OF GAIN AND LOSS OF ETHANOL ALLOSTERIC POTENTIATION BY RESIDUES WITHIN THE GLYCINE RECEPTOR

Aguayo, LG; Yevenes, GE; Moraga-Cid G.; Avila A.; Guzman L.; Figueroa M.; Peoples, RW

Article
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH  (2010)

Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Selective G beta gamma Modulation

Yevenes, GE; Moraga-Cid G.; Avila A.; Guzman L.; Figueroa M.; Peoples, RW; Aguayo, LG

Article
JOURNAL OF BIOLOGICAL CHEMISTRY  (2010)

Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Selective G beta gamma Modulation

Yevenes, GE; Moraga-Cid, G; Avila, A; Guzman, L; Figueroa, M; Peoples, RW; Aguayo, LG

Article ISI SCOPUS
Journal of Biological Chemistry  (2010)

The Light Conduction in an Antenna of a Phycobilisome

Sepulveda-Ugarte, JR; Figueroa M.; Martinez-Oyanedel J.; Bunster, MC

Article
BIOPHYSICAL JOURNAL  (2010)

Biophysical studies support a predicted superhelical structure with armadillo repeats for Ric-8

Figueroa M.; Hinrichs, MV; Bunster M.; Babbitt, P; Martinez-Oyanedel J.; Olate, J

Article
PROTEIN SCIENCE  (2009)

Biophysical studies support a predicted superhelical structure with armadillo repeats for Ric-8

Figueroa, M; Hinrichs, MV; Bunster, M; Babbitt, P; Martinez-Oyanedel, J; Olate, J

Article ISI SCOPUS
PROTEIN SCIENCE  (2009)

Blockade of Ethanol-Induced Potentiation of Glycine Receptors by a Peptide That Interferes with GB gamma Binding

Guzman, L; Moraga-Cid, G; Avila, A; Figueroa, M; Yevenes, GE; Fuentealba, J; Aguayo, LG

Article ISI SCOPUS
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS  (2009)

Blockade of Ethanol-Induced Potentiation of Glycine Receptors by a Peptide That Interferes with GB gamma Binding

Guzman L.; Moraga-Cid G.; Avila A.; Figueroa M.; Yevenes, GE; Fuentealba, J; Aguayo, LG

Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS  (2009)

A semiempirical approach to the intra-phycocyanin and inter-phycocyanin fluorescence resonance energy-transfer pathways in phycobilisomes.

Matamala, Adelio R; Almonacid, Daniel E; Figueroa, Maximiliano F; Martínez-Oyanedel, José; Bunster, Marta C

Article
Journal of computational chemistry  (2007)

The structure at 2 angstrom resolution of Phycocyanin from Gracilaria chilensis and the energy transfer network in a PC-PC complex

Contreras-Martel, C; Matamala Á.; Bruna, C; Poo-Caamano, G; Almonacid D; Figueroa, M; Martinez-Oyanedel, J; Bunster, M

Article ISI SCOPUS
BIOPHYSICAL CHEMISTRY  (2007)

The structure at 2 angstrom resolution of Phycocyanin from Gracilaria chilensis and the energy transfer network in a PC-PC complex

Contreras-Martel, C; Matamala, A; Bruna, C; Poo-Caamano, G; Almonacid, D; Figueroa M.; Martinez-Oyanedel J.; Bunster M.

Article
BIOPHYSICAL CHEMISTRY  (2007)

In situ photoacoustic spectroscopy of phycobiliproteins in Gracilaria chilensis

Saavedra, R; Figueroa M.; Wandersleben, T; Pouchucq, L; Morales, JE; Bunster M.; Cruz-Orea, A

Article
JOURNAL DE PHYSIQUE IV  (2005)

In situ photoacoustic spectroscopy of phycobiliproteins in Gracilaria chilensis

Saavedra, R; Figueroa, M; Wandersleben, T; Pouchucq L.; Morales, JE; Bunster, M; Cruz-Orea, A

Article ISI SCOPUS
JOURNAL DE PHYSIQUE IV  (2005)

Abstract (2)

CONTROL OF GAIN AND LOSS OF ETHANOL ALLOSTERIC POTENTIATION BY RESIDUES WITHIN THE GLYCINE RECEPTOR

Aguayo, LG; Yevenes, GE; Moraga-Cid, G; Avila, A; Guzman, L; Figueroa, M; Peoples, RW

Abstract ISI
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH  (2010)

The Light Conduction in an Antenna of a Phycobilisome

Sepulveda-Ugarte, JR; Figueroa, M; Martinez-Oyanedel, J; Bunster, MC

Abstract ISI
BIOPHYSICAL JOURNAL  (2010)

Proyecto (5)

Influence of mass transport and surface growth processes on protein crystal perfection

PRODEX-BELSPO (ESA A0-2004-070)

Proyecto
2012-2015
Postdoctorado

Structural characterization and functionalization of Octarellins, artificial proteins with (beta/alfa)8 fold

BELSPO-WBI (No aplica)

Proyecto
2010-2012
Postdoctorado

Characterization of RIC-8, a Novel Non-Receptor G-Protein Regulator

FONDECYT (1090150)

Proyecto
2009-2010
Tesista

Structure-Function Studies of a Phycobilisome, a Model of High Efficient System of Light Conduction

FONDECYT (1080267)

Proyecto
2008-2010
Personal técnico y/o de apoyo

Advanced Studies in Cellular Signaling and Gene Regulation

PIA (ACT44)

Proyecto
2005-2008
Tesista

Review (2)

Host cell factors involved in classical swine fever virus entry

Lamothe-Reyes, Yaneysis; Figueroa, Maximiliano; Sanchez, Oliberto

Review ISI
VETERINARY RESEARCH  (2023)

Functional analysis of the Mn2+ requirement in the catalysis of ureohydrolases arginase and agmatinase - a historical perspective

Uribe E.; Reyes M.-B.; Martínez I.; Mella K.; Salas M.; Tarifeño-Saldivia E.; López V.; García-Robles M.; Martínez-Oyanedel J.; Figueroa M.; Carvajal N.; Schenk G.

Review ISI SCOPUS
 (2020)

22
Maximiliano Figueroa

Profesor Asociado

Bioquímica y Biología Molecular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

10
Maximiliano Figueroa

Assstant Professor

Universidad de Concepción

Concepción, Chile

6
José Martínez

Associate professor

Bioquímica y Biología Molecular

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

6
Marta Cecilia Bunster

DIRECTORA

Biochemistry and Molecular Biology

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

5
Elena Uribe

Associate Professor

Biochemistry and Molecular Biology

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

5
Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

3
María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

3
Gustavo Moraga

Profesor Asistente

Departamento de Fisiología

Universidad De Concepción

Concepción, Chile

2
JOSE GUZMAN

Full professor

Fisiología

Universidad de Concepción

Concepcion, Chile

2
Gonzalo Yévenes

Associate Professor

Universidad de Concepcion

Concepcion, Chile

2
Vasthi López

Profesor Asociado

Departamento de Ciencias Biomédicas

Universidad Católica del Norte

Coquimbo, Chile

2
Jorge Dagnino

Investigador Postdoctoral

Universidad de Concepción

Concepción, Chile

1
Loreto San Martín

1
Rubén Fritz

Investigador Post-Doctoral

Física

Universidad de Santiago

Santiago, Chile

1
Patricio Castro

profesor asistente

fisiologia

UNIVERSIDAD Concepcion

concepcion, Chile

1
Estefanía Tarifeño

Assistant professor

Bioquímica y Biología Molecular

Universidad de Concepción

Concepción, Chile

1
Carlos Burgos

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

1
Arturo Fernández

Profesor Asociado

Departamento de Física

Universidad del Bío-Bío

Concepción, Chile

1
Fabiola Medina

Académico

Departamento de Química

Universidad del Bío-Bío

Concepción, Chile

1
Daniel Almonacid

Assistant Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

1
Víctor Castro

Profesor Asistente

Departamento de Biología

UNIVERSIDAD DE CHILE

Ñuñoa, Chile

1
Nicolás Riffo

Estudiante de Doctorado

Departamento de Fisiología

Universidad de Concepción

Concepción, Chile

1
JORGE FUENTEALBA

Dean

Physiology

UNIVERISDAD DE CONCEPCION

Concepcion, Chile

1
Carola Bruna

Profesor Asociado

Bioquímica y Biología Molecular

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE CIENCIAS BIOLÓGICAS

Concepción, Chile

1
David García

Profesor Asistente

Ciencias Biológicas y Químicas

UNIVERSIDAD SAN SEBASTIAN

Concepción, Chile

1
Traudy Wandersleben

Académico

Ciencias Químicas y Recursos Naturales

Universidad de La Frontera

Temuco, Chile

1
Renato Saavedra

UNIVERSIDAD DE CONCEPCIÓN, FAC. CS. FÍSICAS Y MATEMÁTICAS, DEPTO. DE FÍSICA

Concepcion, Chile