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Luis Alejandro Piña Iturbe

Investigador Postdoctoral

Pontificia Universidad Católica de Chile

Santiago, Chile

My research focus on genetics and genomics of bacterial pathogens, especially in the molecular epidemiology of emerging pathogens, horizontal gene transfer and antibiotic resistance.

Genética Molecular y Microbiología, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2017
Ciencias Biológicas, Universidad Nacional de Trujillo. Peru, 2011
Biólogo Microbiólogo, Universidad Nacional de Trujillo. Peru, 2014
Genética Molecular y Microbiología, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2021

Ayudante Meritorio Other

Universidad Nacional de Trujillo

Ciencias Biológicas

Trujillo, Peru

2012 - 2012
Investigador Postdoctoral Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

2023 - At present

Asistente de Investigación Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2020 - 2021
Investigador PhD Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2021 - 2023


Genomic characterisation of the population structure and antibiotic resistance of<i> Salmonella</i><i> enterica</i> serovar Infantis in Chile, 2009-2022 Pina-Iturbe, Alejandro; Diaz-Gavidia, Constanza; Alvarez, Francisca P.; Barron-Montenegro, Rocio; Alvarez-Espejo, Diana M.; Garcia, Patricia; Solis, Doina; Constenla-Albornoz, Rodrigo; Toro, Magaly; Olivares-Pacheco, Jorge; Reyes-Jara, Angelica; Meng, Jianghong; Bell, Rebecca L.; Moreno-Switt, Andrea I. Article ISI LANCET REGIONAL HEALTH-AMERICAS (2024)
Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adults Mendez, Constanza; Penaloza, Hernan F.; Schultz, Barbara M.; Pina-Iturbe, Alejandro; Rios, Mariana; Moreno-Tapia, Daniela; Pereira-Sanchez, Patricia; Leighton, Diane; Orellana, Claudia; Covarrubias, Consuelo; Galvez, Nicolas M. S.; Soto, Jorge A.; Duarte, Luisa F.; Rivera-Perez, Daniela; Vazquez, Yaneisi; Cabrera, Alex; Bustos, Sergio; Iturriaga, Carolina; Urzua, Marcela; Navarrete, Maria S.; Rojas, Alvaro; Fasce, Rodrigo A.; Fernandez, Jorge; Mora, Judith; Ramirez, Eugenio; Gaete-Argel, Aracelly; Acevedo, Monica; Valiente-Echeverria, Fernando; Soto-Rifo, Ricardo; Weiskopf, Daniela; Grifoni, Alba; Sette, Alessandro; Zeng, Gang; Meng, Weining; Gonzalez-Aramundiz, Jose V.; Gonzalez, Pablo A.; Abarca, Katia; Melo-Gonzalez, Felipe; Bueno, Susan M.; Kalergis, Alexis M.; CoronaVac03CL Study Grp Article ISI EBIOMEDICINE (2023)
SEN1990 is a predicted winged helix-turn-helix protein involved in the pathogenicity of <i>Salmonella enterica</i> serovar Enteritidis and the expression of the gene <i>oafB</i> in the SPI-17 Hoppe-Elsholz, Guillermo; Pina-Iturbe, Alejandro; Vallejos, Omar P.; Suazo, Isidora D.; Sepulveda-Alfaro, Javiera; Pereira-Sanchez, Patricia; Martinez-Balboa, Yohana; Catalan, Eduardo A.; Reyes, Pablo; Scaff, Valentina; Bassi, Franco; Campos-Gajardo, Sofia; Aviles, Andrea; Santiviago, Carlos A.; Kalergis, Alexis M.; Bueno, Susan M. Article ISI FRONTIERS IN MICROBIOLOGY (2023)
Subinhibitory antibiotic concentrations promote the excision of a genomic island carried by the globally spread carbapenem- resistant<i> Klebsiella</i><i> pneumoniae</i> sequence type 258 Pina-Iturbe, Alejandro; Hoppe-Elsholz, Guillermo; Suazo, Isidora D.; Kalergis, Alexis M.; Bueno, Susan M. Article ISI MICROBIAL GENOMICS (2023)
A Booster Dose of CoronaVac Increases Neutralizing Antibodies and T Cells that Recognize Delta and Omicron Variants of Concern Schultz, Barbara M.; Melo-Gonzalez, Felipe; Duarte, Luisa F.; Galvez, Nicolas M. S.; Pacheco, Gaspar A.; Soto, Jorge A.; Berrios-Rojas, Roslye, V; Gonzalez, Liliana A.; Moreno-Tapia, Daniela; Rivera-Perez, Daniela; Rios, Mariana; Vazquez, Yaneisi; Hoppe-Elsholz, Guillermo; Andrade-Parra, Catalina A.; Vallejos, Omar P.; Pina-Iturbe, Alejandro; Iturriaga, Carolina; Urzua, Marcela; Navarrete, Maria S.; Rojas, Alvaro; Fasce, Rodrigo; Fernandez, Jorge; Mora, Judith; Ramirez, Eugenio; Gaete-Argel, Aracelly; Acevedo, Monica; Valiente-Echeverria, Fernando; Soto-Rifo, Ricardo; Weiskopf, Daniela; Grifoni, Alba; Sette, Alessandro; Zeng, Gang; Meng, Weining; Gonzalez-Aramundiz, Jose, V; Gonzalez, Pablo A.; Abarca, Katia; Kalergis, Alexis M.; Bueno, Susan M.; CoronaVacO3CL Study Grp Article ISI MBIO (2022)
BCG-Based Vaccines Elicit Antigen-Specific Adaptive and Trained Immunity against SARS-CoV-2 and Andes orthohantavirus Soto, Jorge A.; Diaz, Fabian E.; Retamal-Diaz, Angello; Galvez, Nicolas M. S.; Melo-Gonzalez, Felipe; Pina-Iturbe, Alejandro; Ramirez, Mario A.; Bohmwald, Karen; Gonzalez, Pablo A.; Bueno, Susan M.; Kalergis, Alexis M. Article ISI VACCINES (2022)
Bioinformatic and experimental characterization of SEN1998: a conserved gene carried by the Enterobacteriaceae-associated ROD21-like family of genomic islands Pina-Iturbe, Alejandro; Hoppe-Elsholz, Guillermo; Fernandez, Paulina A.; Santiviago, Carlos A.; Gonzalez, Pablo A.; Bueno, Susan M. Article ISI SCIENTIFIC REPORTS (2022)
Inactivated Vaccine-Induced SARS-CoV-2 Variant-Specific Immunity in Children Soto, Jorge A.; Melo-Gonzalez, Felipe; Gutierrez-Vera, Cristian; Schultz, Barbara M.; Berrios-Rojas, Roslye, V; Rivera-Perez, Daniela; Pina-Iturbe, Alejandro; Hoppe-Elsholz, Guillermo; Duarte, Luisa F.; Vazquez, Yaneisi; Moreno-Tapia, Daniela; Rios, Mariana; Palacios, Pablo A.; Garcia-Betancourt, Richard; Santibanez, Alvaro; Pacheco, Gaspar A.; Mendez, Constanza; Andrade, Catalina A.; Silva, Pedro H.; Diethelm-Varela, Benjamin; Astudillo, Patricio; Calvo, Mario; Cardenas, Antonio; Gonzalez, Marcela; Goldsack, Macarena; Gutierrez, Valentina; Potin, Marcela; Schilling, Andrea; Tapia, Lorena, I; Twele, Loreto; Villena, Rodolfo; Grifoni, Alba; Sette, Alessandro; Weiskopf, Daniela; Fasce, Rodrigo A.; Fernandez, Jorge; Mora, Judith; Ramirez, Eugenio; Gaete-Argel, Aracelly; Acevedo, Monica L.; Valiente-Echeverria, Fernando; Soto-Rifo, Ricardo; Retamal-Diaz, Angello; Munoz-Jofre, Nathalia; PedCoronaVac; Meng, Xing; Xin, Qianqian; Alarcon-Bustamante, Eduardo; Gonzalez-Aramundiz, Jose, V; Le Corre, Nicole; Javiera Alvarez-Figueroa, Maria; Gonzalez, Pablo A.; Abarca, Katia; Perret, Cecilia; Carreno, Leandro J.; Bueno, Susan M.; Kalergis, Alexis M. Article ISI MBIO (2022)
L-Arginine Enhances Intracellular Killing of Carbapenem-Resistant Klebsiella pneumoniae ST258 by Murine Neutrophils Penaloza, Hernan F.; Ahn, Danielle; Schultz, Barbara M.; Pina-Iturbe, Alejandro; Gonzalez, Liliana A.; Bueno, Susan M. Article ISI FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)
Comparative and phylogenetic analysis of a novel family of Enterobacteriaceae-associated genomic islands that share a conserved excision/integration module Pina-Iturbe, A; Ulloa-Allendes, D; Pardo-Roa, C; Coronado-Arrazola, I; Salazar-Echegarai, FJ; Sclavi, B; Gonzalez PA; Bueno, SM Article ISI SCOPUS SCIENTIFIC REPORTS (2018)
Constituents from the bark resin of Schinus molle Malca-Garcia, Gonzalo Rodolfo; Hennig, Lothar; Luis Ganoza-Yupanqui, Mayar; Pina-Iturbe, Alejandro; Bussmann, Rainer W. Article ISI REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY (2017)


Bioinformatic Characterization of the Excisable Genomic Island ICEKp258.2 Associated to the Globally Spread Carbapenem-resistant Klebsiella pneumoniae ST258 Piña-Iturbe, Alejandro; Hoppe-Elsholz, Guillermo; Bueno, Susan M. ConferencePoster (2021)
Bioinformatic Characterization, Purification and Binding Assays of SEN1998: A Putative Recombination Directionality Factor Conserved among the Enterobacteriaceae-associated ROD21-like Family of Genomic Islands Piña-Iturbe, Alejandro; Hoppe-Elsholz, Guillermo; Fernández, Paulina A.; Santiviago, Carlos A.; González, Pablo A.; Bueno, Susan M. ConferencePoster (2021)
Characterization of a potential recombination directionality factor encoded in the pathogenicity island ROD21 of Salmonella enterica serovar Enteritidis Piña-Iturbe, A.; Hoppe-Elsholz, Guillermo; González, Pablo A.; Bueno, Susan M. ConferencePoster (2019)
Antibacterial Activity of Plants Used to Treat Cardiac Problems and Infectious Disease by the Curanderos of Northern Peru Frisch, E. H.; Willsky, G. R.; Arellano, A.; Carnevale, L.; Ortiz, J.; Cleland, T.; Brooks, K.; Bakaj, E.; Rodriguez, G.; Bussman, R.; Sharon, D.; Tellez, C.; Castro, I. Y.; Crane, J.; Piña Iturbe, A.; Ganoza, M. ConferencePoster (2015)


Chromosomal Excision Regulation of the Salmonella enterica serovar Enteritidis pathogenicity island ROD21 Piña-Iturbe, Alejandro Proyecto Proyecto para Beca de Doctorado Nacional (2017)


Horizontally Acquired Homologs of Xenogeneic Silencers: Modulators of Gene Expression Encoded by Plasmids, Phages and Genomic Islands PiÃ±a-Iturbe A.; Suazo I.D.; Hoppe-Elsholz G.; Ulloa-Allendes D.; GonzÃ¡lez P.A.; Kalergis A.M.; Bueno, S. M. Review ISI SCOPUS GENES (2020)