Man

María Javiera Alvarez Figueroa

Profesor Asociado

Pontificia Universidad Catolica de Chile

Santiago, Chile

Líneas de Investigación


Absorción de moléculas a través de la piel mediante estudios Ex vivo empleando piel de cerdo neonato y estudio de penetración de moléculas a través de membranas biológicas simuladas (PAMPA).

Educación

  •  Tecnología Farmacéutica, Universidad de Santiago de Compostela. España, 2001

 

Article (22)

Design of an innovative nanovehicle to enhance brain permeability of a novel 5-HT6 receptor antagonist

ALVAREZ-FIGUEROA, MARIA JAVIERA; Nunez-Navarro, Francisco; Recabarren-Gajardo, Gonzalo; Gonzalez-Aramundiz, Jose Vicente

Article ISI SCOPUS
International Journal of Pharmaceutics: X  (2024)

Vernix caseosa reveals mechanistic clues linking maternal obesity to atopic dermatitis pathogenesis

Cabalin, Carolina; Dibarrart, Marisol; Nunez-Rosales, Juan Jose; Faunes, Miriam; Avaca, Monica; Avalos, Patricia; Fabres, Jorge; ALVAREZ-FIGUEROA, MARIA JAVIERA; Vera-Kellet, Cristian; Silva-Valenzuela, Sergio; et al.

Article ISI
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY  (2024)

Different Safety Pattern of an Inactivated SARS-CoV-2 Vaccine (CoronaVac®) According to Age Group in a Pediatric Population from 3 to 17 Years Old, in an Open-Label Study in Chile

Abarca, Katia; Potin, Marcela; Calvo, Mario; Twele, Loreto; Reyes, Felipe; Villena, Rodolfo; Bueno, Susan M.; Perret, Cecilia; PedCoronaVac03CL Study Grp

Article ISI
VACCINES  (2023)

Innovative multiple nanoemulsion (W/O/W) based on Chilean honeybee pollen improves their permeability, antioxidant and antibacterial activity

Valdivia-Olivares, Rayen Yanara; Martinez-Gonzalez, E. A.; MONTENEGRO-RIZZARDINI, GLORIA DEL CARMEN; Bridi, Raquel; ALVAREZ-FIGUEROA, MARIA JAVIERA; González-Aramundiz, José V.

Article ISI SCOPUS
FOOD RESEARCH INTERNATIONAL  (2023)

Dextran Nanocapsules with omega-3 in Their Nucleus: An Innovative Nanosystem for Imiquimod Transdermal Delivery

Carreño, Gisela F.; ALVAREZ-FIGUEROA, MARIA JAVIERA; González-Aramundiz, José V.

Article ISI SCOPUS
Pharmaceutics  (2022)

Effect of zeta potential of innovative lipid nanocapsules on triamcinolone transdermal delivery

ALVAREZ-FIGUEROA, MARIA JAVIERA; Alarcon, Diego A.; González-Aramundiz, José V.

Article ISI SCOPUS
Drug Delivery and Translational Research  (2022)

Inactivated Vaccine-Induced SARS-CoV-2 Variant-Specific Immunity in Children

Vazquez, Yaneisi; Rios, Mariana; Palacios, Pablo A.; Garcia-Betancourt, Richard; Santibañez, Álvaro; Silva, Pedro H.; Calvo, Mario; Cardenas, Antonio; Goldsack, Macarena; Potin, Marcela; et al.

Article ISI
mBio  (2022)

The Importance of Nanocarrier Design and Composition for an Efficient Nanoparticle-Mediated Transdermal Vaccination

Valdivia-Olivares, Rayen Yanara; Rodriguez-Fernandez, Maria; ALVAREZ-FIGUEROA, MARIA JAVIERA; Kalergis, Alexis M.; González-Aramundiz, José V.

Article ISI SCOPUS
Vaccines  (2021)

Design of Chitosan Nanocapsules with Compritol 888 ATO® for Imiquimod Transdermal Administration. Evaluation of Their Skin Absorption by Raman Microscopy

Carrasco-Flores, Eduardo A.

Article ISI
PHARMACEUTICAL RESEARCH  (2020)

Optimization of physicochemical properties of novel multiple nanoemulsion for complex food matrices through iterative mathematical modelling

Valdivia-Olivares R.Y.

Article ISI SCOPUS
 (2020)

Effect of the aggregation state of bile salts on their transdermal absorption enhancing properties

Muggli-Galaz C.

Article ISI SCOPUS
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY  (2019)

Influence of protamine shell on nanoemulsions as a carrier for cyclosporine-A skin delivery



Article ISI
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY  (2019)

Use of DMPC and DSPC lipids for verapamil and naproxen permeability studies by PAMPA

Alvarez Figueroa MJ; Contreras-Garrido, BC; Soto-Arriaza, MA

Article ISI SCOPUS
Drug Development and Industrial Pharmacy  (2015)

Evaluation of the membrane permeability (PAMPA and skin) of benzimidazoles with potential cannabinoid activity and their relation with the biopharmaceutics classification system (BCS)

Alvarez-Figueroa M.J., Pessoa -Mahana C. David; Palavecino-González M.E., Mella- Raipán J.; Espinoza Bustoa C, Lagos-Muñoz M.E.

Article
AAPS PharmSciTech  (2011)

Scavenging activity of diclofenac interaction with ABTS radical cation and peroxyl radicals

Alvarez-Figueroa M.J., Rojo-Vergara C.; López-Alarcón C, Soto L.M.; Cañete A., Pessoa-Mahana C. D.

Article
Journal of the Chilean Chemical Society  (2009)

Transdermal penetration of diclofenac in the presence of AAPH-derived peroxyl radicals

Rojo-Vergara, C; Lopez-Alarcon, C; Alvarez Figueroa MJ

Article ISI SCOPUS
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY  (2009)

Influence of lipophilia and of the vehicle employed in the transdermal absorption of novel benzimidazole compounds with possible anti-HIV activity

Alvarez-Figueroa M.J., Pessoa -Mahana C. David

Article
Pharmaceutical Development and Technology  (2008)

Passive and iontophoretic transdermal penetration of chlorpromazine

Alvarez-Figueroa M.J., González-Aramundiz J.V.

Article
Pharmaceutical Development and Technology  (2008)

1-BENZOYL-2-(2-NITROPHENYL)-1H-BENZIMIDAZOLE DERIVATIVES: A NOVEL APPROACH TO THE DEVELOPMENT OF NEW HIV-1 REVERSE TRANSCRIPTASE INHIBITORS

Vásquez D.; Lagos, CF; Mella-Raipan J.; González, L.; Ebensperger, R; Alvarez Figueroa MJ; Saez, E.; Pessoa-Mahana H.; Araya-Secchi R.; Gonzalez-Wong, A; et al.

Article ISI SCIELO SCOPUS
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY  (2007)

Iontophoretic transdermal delivery of haloperidol

Alvarez Figueroa MJ; Araya-Silva, I; Diaz-Tobar, C

Article ISI SCOPUS
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY  (2006)

Passive and iontophoretic transdermal penetration of methotrexate

Alvarez Figueroa MJ; Delgado-Charro, MB; Blanco-Mendez, J

Article ISI SCOPUS
INTERNATIONAL JOURNAL OF PHARMACEUTICS  (2001)

Transdermal delivery of methotrexate: iontophoretic delivery from hydrogels and passive delivery from microemulsions

Alvarez Figueroa MJ; Blanco-Mendez, J

Article ISI SCOPUS
INTERNATIONAL JOURNAL OF PHARMACEUTICS  (2001)

Proyecto (4)

“Chemical materials nanostructured as a new carrier that promote both antibacterial and transdermal drug delivery functions for the treatment skin autoimmune diseases”

Alvarez Figueroa, María Javiera; González Aramundiz, José Vicente; Borzutzky Schachter, Arturo José

Proyecto
 (2024)

“INTherVac: Innovative mRNA-Nanovaccines as a Thermostable platform for needle-free Vaccination”

González Aramundiz, José Vicente; Alvarez Figueroa, María Javiera

Proyecto
 (2024)

"Impact of vernix caseosa on the epidermal barrier and infection susceptibility: groundwork for a novel treatment against atopic dermatitis"

Borzutzky Schachter, Arturo José; Alvarez Figueroa, María Javiera

Proyecto
 (2020)

“InNaVac: Innovative Multifunctional Nanocapsules for Transdermal Vaccine Delivery”

González Aramundiz, José Vicente; Alvarez Figueroa, María Javiera

Proyecto
 (2020)

1
Marco Soto

Profesor Asociado

Química Física

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Camilo López

prof. Asociado

Química Física

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Lorena Tapia

Profesora Asociada

Departamento de Pediatría y Cirugía Infantil Norte

Universidad de Chile

Santiago, Chile

1
Monica Acevedo

Profesor Asistente

Instituto de Ciencias Biomédicas

UNIVERSIDAD DE CHILE

Santiago, Chile

1
David Vásquez

Profesor Asistente

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Arturo Borzutzky

Chief; Associate Professor

Department of Pediatric Infectious Diseases and Immunology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Roberto Ebensperger

Associate Professor

Pharmacy

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Tomas Perez-Acle

Full Professor

Computational Biology Lab

Fundación Ciencia para la Vida

Santiago, Chile

2
Monique Le Corre

Assistant Professor

Faculty of medicine, Pediatric division

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
María Rodríguez

Profesora Asociada

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

22
María Alvarez

Profesor Asociado

Farmacia

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
José González

Profesor asistente

Facultad de Química

Pontificia Universidad Católica de Chile

Santiago, Chile

1
JAIME MELLA

PROFESOR ADJUNTO

INSTITUTO DE QUIMICA Y BIOQUIMICA

UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

1
Christian Muñoz

Profesor Asociado

Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

1
Fernando Valiente

Profesor Asociado

ICBM

Universidad de Chile

Santiago, Chile

1
Pablo González

Asesor Farmacéutico

Asesor Farmacéutico

Santiago, Chile

2
ANGELLO RETAMAL

Profesor Asistente

Biotecnología

Universidad de Antofagasta

Antofagasta, Chile

2
Jorge Soto

Profesor Asociado

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
FELIPE MELO

Profesor Asistente

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
Luis Piña

Investigador Postdoctoral

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Alvaro Santibañez

Estudiante de doctorado. pHD (c)

Instituto de Ciencias Biomédicas (ICBM)

Universidad de Chile

Santiago, Chile

2
Eduardo Alarcón

1
Rayen Valdivia

Estudiante de doctorado

Instituto de ingeniería biológica y médica

Pontificia Universidad Católica de Chile

santiago, Chile

1
LUISA DUARTE

Assistant Researcher Professor

Instituto de Ciencias e innovación en Medicina, Facultad de Medicina

Universidad del Desarrollo

Santiago, Chile

1
Javiera Cortés

Estudiante de Doctorado

Instituto de Ingeniería Biológica y Médica

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Nicolas Armijo

Senior Research Associate

Epsilon Research

santiago, Chile

2
Cecilia Perret

Jefa de departamento

Enfermedades Infecciosas e Inmunología Pediátrica

Pontificia Universidad Católica de Chile

Santiago, Chile