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Lorena Isabel Tapia Faundes

Profesora Asociada

Universidad de Chile

Santiago, Chile

Infección por virus respiratorios en pediatría. Variabilidad Genetica en Virus Respiratorio Sincicial; Genetica del hospedero frente a la infeccion por VRS; Evolucion clinica posterior a la infeccion por VRS, desarrollo de sibilancias recurrentes

Virology, UNIVERSIDAD DE CHILE. Chile, 2010
Medical Doctor, UNIVERSIDAD DE CHILE. Chile, 2003
Pediatrics, UNIVERSIDAD DE CHILE. Chile, 2010
Infectious Diseases Specialist, UNIVERSIDAD DE CHILE. Chile, 2020

Profesora Asociada Part Time

UNIVERSIDAD DE CHILE

Facultad de Medicina

SANTIAGO, Chile

2008 - At present
Profesora Asociada Part Time

UNIVERSIDAD DE CHILE

Facultad de Medicina

SANTIAGO, Chile

2008 - At present
Assistant Professor Full Time

BAYLOR COLLEGE OF MEDICINE

Houston, TX, Estados Unidos

2010 - 2012

Pediatra Urgencia Escolar Part Time

Clínica Santa María

SANTIAGO, Chile

2008 - 2010
Pediatra Part Time

Clínica Las Condes

SANTIAGO, Chile

2016 - 2021
Pediatra Infectóloga Part Time

Clinica Universidad de Los Andes

Santiago, Chile

2021 - At present


Strategies and recommendations to face respiratory syncytial virus disease in 2024 Paris, Enrique; Daza, Paula; Tapia, Lorena; Diaz, Juan Pablo; Romero, Pablo Cruces; Castillo, Andres; Gonzalez, Cecilia; Endeiza, Maria Luz; Jofre, Leonor; Castro, Fabiola; Zamorano, Alejandra; Rodriguez, Jaime; Acevedo, Johanna; Santa Cruz, Teresita; Gonzalez, Jaime; Escarate, Raul; Moreno, Juan Pablo; Cisternas, Paula Article ISI ANDES PEDIATRICA (2024)
Different Safety Pattern of an Inactivated SARS-CoV-2 Vaccine (CoronaVac®) According to Age Group in a Pediatric Population from 3 to 17 Years Old, in an Open-Label Study in Chile Le Corre, Nicole; Abarca, Katia; Astudillo, Patricio; POTIN-SANTANDER, MARCELA; Lopez, Sofia; Goldsack, Macarena; Valenzuela, Vania; SCHILLING-REDLICH, ANDREA INGRID; Gaete, Victoria; Rubio, Lilian; CALVO-ARELLANO, MARIO; Twele, Loreto; González, Marcela; Fuentes, Daniela; Gutierrez, Valentina; Reyes, Felipe; Tapia, Lorena I.; VILLENA-MARTINEZ, RODOLFO JAVIER; RETAMAL-DIAZ, ANGELLO RICARDO; Cárdenas, Antonio; Alarcon-Bustamante, Eduardo; Meng, Xing; Xin, Qianqian; GONZALEZ-ARAMUNDIZ, JOSE, V; ALVAREZ-FIGUEROA, MARIA JAVIERA; Gonzalez, Pablo A.; BUENO-RAMIREZ, SUSAN MARCELA; Soto, Jorge A.; PERRET-PEREZ, CECILIA; Kalergis, Alexis M.; PedCoronaVac03CL Study Grp Article ISI SCOPUS Vaccines (2023)
Inactivated Vaccine-Induced SARS-CoV-2 Variant-Specific Immunity in Children Soto, Jorge A.; Melo-Gonzalez, Felipe; Gutierrez-Vera, Cristian; Schultz, Barbara M.; Berrios-Rojas, Roslye, V; Rivera-Perez, Daniela; Pina-Iturbe, Alejandro; Hoppe-Elsholz, Guillermo; Duarte, Luisa F.; Vazquez, Yaneisi; Moreno-Tapia, Daniela; Rios, Mariana; Palacios, Pablo A.; Garcia-Betancourt, Richard; Santibanez, Alvaro; Pacheco, Gaspar A.; Mendez, Constanza; Andrade, Catalina A.; Silva, Pedro H.; Diethelm-Varela, Benjamin; Astudillo, Patricio; Calvo, Mario; Cardenas, Antonio; Gonzalez, Marcela; Goldsack, Macarena; Gutierrez, Valentina; Potin, Marcela; Schilling, Andrea; Tapia, Lorena, I; Twele, Loreto; Villena, Rodolfo; Grifoni, Alba; Sette, Alessandro; Weiskopf, Daniela; Fasce, Rodrigo A.; Fernandez, Jorge; Mora, Judith; Ramirez, Eugenio; Gaete-Argel, Aracelly; Acevedo, Monica L.; Valiente-Echeverria, Fernando; Soto-Rifo, Ricardo; Retamal-Diaz, Angello; Munoz-Jofre, Nathalia; PedCoronaVac; Meng, Xing; Xin, Qianqian; Alarcon-Bustamante, Eduardo; Gonzalez-Aramundiz, Jose, V; Le Corre, Nicole; Javiera Alvarez-Figueroa, Maria; Gonzalez, Pablo A.; Abarca, Katia; Perret, Cecilia; Carreno, Leandro J.; Bueno, Susan M.; Kalergis, Alexis M. Article ISI MBIO (2022)
Cytokine and chemokine profiles in episodes of persistent high-risk febrile neutropenia in children with cancer Tapia, Lorena I.; Mauricio Olivares; Torres, Juan P.; De la Maza, Verónica; Valenzuela, Romina; Contardo P, Verónica; Santolaya, María E Article ISI CYTOKINE (2021)
Multisystem inflammatory syndrome in children and adults (MIS-C/A): definition & guidelines for data collection, analysis, and presentation of immunization safety data Vogel, Tiphanie P.; Top, Karina A.; Karatzios, Christos; Hilmers, David C.; Tapia, Lorena, I; Moceri, Pamela; Giovannini-Chami, Lisa; Wood, Nicholas; Chandler, Rebecca E.; Klein, Nicola P.; Schlaudecker, Elizabeth P.; Cecilia Poli, M.; Muscal, Eyal; Munoz, Flor M. Article ISI VACCINE (2021)
N-6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication Figueroa, Fabian; Vega-Gibson, Alonso; Catrileo, Joseline; Gaete-Argel, Aracelly; Riquelme-Barrios, Sebastian; Antonio Alonso-Palomares, Luis; Tapia, Lorena, I; Valiente-Echeverria, Fernando; Soto-Rifo, Ricardo; Acevedo, Monica L. Article ISI FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Pediatric multisystem SARS COV2 with versus without cardiac involvement: a multicenter study from Latin America Pignatelli, Ricardo; Antona, Clara Vazquez; Rivera, Ivan Romero; Zenteno, Patricia Alvarez; Acosta, Yanet Toribio; Huertas-Quinones, Manuel; Murillo, Carlos Alvarez; Torres, Franklin Mendoza; Cabalin, Carlos Fernandez; Camacho, Ana Galvan; Perez, Alex Alcantara; Lombardi, Ana Braga; Soares, Andressa Mussi; Garcia, Carolina Torres; Borges, Cibelle Teixeira; Villalba, Claudia Natalia; Lechado, Cristhian Ramirez; Dias, Deborah Trevisan; Morales, Diana Aravena; Copete, Elizabeth Mora; Goldenberg, Guillermo Larios; Salazar, Jahaira Sussety; Moreira, Jessica Alchundia; Asakura, Junko; Sabando, Karla Solorzano; Branco, Klebia Castello; Rosas, Lida Toro; Duarte, Magna Pereira; Carbajal, Maria Jimenez; Hernandez, Martha Rubio; Martinez, Moises Mier; Echeverria, Nancy Garay; Caneva, Olga Maza; Sepulveda, Patricia Romero; Diaz, Paulina Agurto; Pluas, Ruth Rugel; Alvarado, Theo Contreras; Faundes, Lorena Tapia; Diaz, Yeny Briones; Zachariah, Justin P. Article ISI EUROPEAN JOURNAL OF PEDIATRICS (2021)
Recommendations for the suspected diagnosis and management of Multisystemic Inflammatory Syndrome (MIS-C) in the context of a SARS-CoV-2 pandemic. April 2021 Izquierdo, Giannina; Cofre, Fernanda; Poli, Cecilia; Delpiano, Luis; Conca, Natalia; Verdugo, Patricia; Alvarez, Patricia; Acevedo, Valeria; Tapia, Lorena Article ISI REVISTA CHILENA DE INFECTOLOGIA (2021)
Clinical manifestations of SARS-CoV-2 infection in children in the middle of pandemic season in a pediatric tertiary center. Report of local COVID Clinical Committee, Hospital de Niños Roberto del Río, Santiago Chile Cofré, Fernanda; Mackenney, Jorge; Poli, Cecilia; Riquelme, Maryel; Carvajal, Cristian; Álvarez, Patricia; Acevedo, Valeria; Valenzuela, M. Lidia; Verdugo, Patricia; Varas, Mónica; Tapia, Lorena Article ISI REVISTA CHILENA DE INFECTOLOGIA (2020)
Compromiso cardiovascular en pacientes con Síndrome Inflamatorio Pediátrico Multisistémico, asociado a infección por SARS-CoV-2 Álvarez, Patricia; Acevedo, Valeria; Valenzuela, María Lidia; Montes, Vicente; Aroca, Patricia; García, Carla; Campos, Carolina; Koch, Katherine; González, Soledad; Poli, Cecilia; Verdugo, Patricia; Cofré, Fernanda; Mackenney, Jorge; Tapia, Lorena Article SCIELO Revista chilena de cardiología (2020)
Multisystem inflammatory syndrome in children (MIS-C): Report of the clinical and epidemiological characteristics of cases in Santiago de Chile during the SARS-CoV-2 pandemic Torres, Juan P.; Izquierdo, Giannina; Acuna, Mirta; Pavez, Daniela; Reyes, Felipe; Fritis, Ana; Gonzalez, Ricardo; Rivacoba, Carolina; Contardo, Veronica; Tapia, Lorena I. Article ISI INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)
Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 Treated with Tocilizumab Nino-Taravilla, Carmen; Espinosa-Vielma, Yazmin P.; Otaola-Arca, Hugo; Poli-Harlowe, Cecilia; Tapia, Lorena, I; Ortiz-Fritz, Paula Article ISI PEDIATRIC REPORTS (2020)
Respiratory viral infections during episodes of fever in children undergoing hematopoietic stem cell transplantation Pablo Torres, Juan; Eugenia Castro-Moraga, Maria; Catalan, Paula; de la Maza, Veronica; Vergara, Alejandra; Valenzuela, Romina; Tapia, Lorena; Olivares-Morales, Mauricio; Farfan, Mauricio J.; Elena Santolaya, Maria Article ISI REVISTA CHILENA DE INFECTOLOGIA (2020)
REPIRATORY SYNCYTIAL VIRUS GENOTYPES, HOST IMMUNE PROFILES, AND DISEASE SEVERITY IN YOUNG CHILDREN HOSPITALIZED WITH BRONCHIOLITIS Rodríguez-Fernández, Rosa; Tapia, Lorena; Fen Yang, Chin; Torres, Juan Pablo; Chávez Bueno, Susana; García, Carla; Jaramillo, Lisa; Moore, Melissa; Jafri, Hasan; Peeples, Mark; Piedra, Pedro; Ramilo, Octavio; Mejías, Ana Asunción Article JOURNAL OF INFECTIOUS DISEASES (2018)
Genomic loads and genotypes of respiratory syncytial virus=> viral factors during lower respiratory tract infection in Chilean hospitalized infants Espinosa, Yazmín; San Martin, Camila; Torres, Alejandro; Farfán, Mauricio; Torres, Juan Pablo; Avadhanula, Vasanthi; Piedra, Pedro; Tapia, Lorena Article INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Intravenous palivizumab in respiratory syncytial virus infection after hematopoietic stem cell transplant in children Torres, Juan Pablo; Tapia, Lorena I.; Catalán, Paula; De la Maza, Verónica; Mejías, Asunción Article ISI SCOPUS PEDIATRIC BLOOD & CANCER (2017)
Intravenous palivizumab in respiratory syncytial virus infection after hematopoietic stem cell transplant in children. Torres, Juan Pablo; Tapia, Lorena I; Catalán, Paula; De la Maza, Verónica; Mejías, Asunción Article Pediatric blood & cancer (2017)
Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B. Hause, Anne M; Henke, David M; Avadhanula, Vasanthi; Shaw, Chad A; Tapia, Lorena I; Piedra, Pedro A Article PloS one (2017)
Gene sequence variability of the three surface proteins of human respiratory syncytial virus (HRSV) in Texas Tapia Lorena I; Shaw Chad A; Aideyan Letisha O; Jewell Alan M; Dawson Brian C; Haq Taha R; Piedra Pedro A Article PloS One (2014)
Lactate dehydrogenase and caspase activity in nasopharyngeal secretions are predictors of bronchiolitis severity MEHTA R.; Scheffler, M; Tapia L.; Aideyan, L; Patel, KD; Jewell, AM; Avadhanula, V; Mei, MH; Garofalo, RP; Piedra, PA Article ISI INFLUENZA AND OTHER RESPIRATORY VIRUSES (2014)
Respiratory syncytial virus infection and recurrent wheezing in Chilean infants: A genetic background? Tapia, LI; Ampuero, S; Palomino, MA; Luchsinger, V; Aguilar N.; Ayarza E.; Mamani, R; Larranaga, C Article INFECTION GENETICS AND EVOLUTION (2013)
SP-A1, SP-A2 and SP-D gene polymorphisms in severe acute respiratory syncytial infection in Chilean infants Ampuero S.; Luchsinger, V.; Tapia L.; Palomino, MA; Larranaga, CE Article ISI SCOPUS INFECTION GENETICS AND EVOLUTION (2011)
Impaired Immune Response in Severe Human Lower Tract Respiratory Infection by Respiratory Syncytial Virus Larranaga, CL; Ampuero, SL; Luchsinger, VF; Carrion, FA; Aguilar, NV; Morales, PR; Palomino, MAM; Tapia, LF; Avendano, LF Article PEDIATRIC INFECTIOUS DISEASE JOURNAL (2009)
Plasma interferon-gamma, interleukin-10 and soluble markers of immune activation in infants with primary adenovirus (ADV) and respiratory syncytial virus (RSV) infection Fernandez, JA; Tapia L.; Palomino, MA; Larrañaga C.; Pena M.; Jaramillo, H Article ISI European Cytokine Network (2005)
Authorship in the Chilean Journal of Otorhinolaryngology and Head and Neck Surgery. Analysis of three decades Tapia L.; Torrente M.; Posada, C. Article ISI REVISTA MEDICA DE CHILE (2002)


COVID-19 y Síndrome Inflamatorio Multisistémico Pediátrico asociado a SARS-CoV-2: Lo positivo de fortalecer el trabajo multidisciplinario Lorena Tapia Faundes Editorial SCIELO ANDES PEDIATRICA (2021)


Human respiratory syncitial virus A, genotype ontario Tapia L.; Alvial, N; Bravo, P EditorialMaterial ISI REVISTA CHILENA DE INFECTOLOGIA (2015)


VIRAL FACTORS, HOST IMMUNE RESPONSE AND NASOPHARYNGEAL MICROBIOTA AS DETERMINANTS OF THE SEVERITY OF RESPIRATORY VIRAL INFECTIONS IN CHILDREN WITH HEMATOPOIETIC STEM CELL TRANSPLANT FONDECYT (1171795) Proyecto 2017-2021 Coinvestigador(a)
Factores virales en la patogénesis del virus respiratorio sincicial=> genotipos y carga viral, ¿afectan el curso de la enfermedad?. Beca SAVAL de Investigación 2014 (xxx) Proyecto 2014-2016 Inv. Patrocinante
GENE SEQUENCE VARIABILITY OF THE THREE SURFACE PROTEINS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS IN SANTIAGO, CHILE. CAN IT AFFECT THE COURSE OF THE DISEASE? FONDECYT (11121536) Proyecto 2012-2015 Inv. Responsable
BIOMARKERS FOR IDENTIFICATION CHILEAN INFANTS AT RISK FOR RESPIRATORY SUNCYTIAL VIRUS (RSV) AND RHINOVIRUS (RV)- INDUCED SEVERE ACUTE LOWER RESPIRATORY INFECTION FONDECYT (1100477) Proyecto 2010-2013 Coinvestigador(a)
INFECCION POR VIRUS RESPIRATORIO SINCICIAL=> ESTUDIO DE POLIMORFISMOS DE LOS GENES IL-4. IL-8. SP-A Y SP-D RELACIONADAS A ENFERMEDAD GRAVE POR VRS EN POBLACION CHILENA SUSCEPTIBLE. FONDECYT (1050513) Proyecto 2005-2008 Personal técnico y/o de apoyo