Man

Matías Alberto Zúñiga Bustos

Postdoctorado

Universidad de Talca

TALCA, Chile

Líneas de Investigación


Simulación computacional de sistemas biológicos (proteína ligando, proteína-proteína, proteína-péptido) y nanomateriales híbridos compuestos por péptidos y nanopartículas inorgánicas.

Educación

  •  Doctorado en Fisicoquímica Molecular, UNIVERSIDAD ANDRÉS BELLO. Chile, 2018
  •  Ingeniero en Bioinformática, UNIVERSIDAD DE TALCA. Chile, 2013

Experiencia Académica

  •   PROFESOR ASISTENTE Full Time

    UNIVERSIDAD TECNOLOGICA METROPOLITANA

    SANTIAGO, Chile

    2022 - At present


 

Article (24)

Unveiling the potential of RADA16-I peptide-coated silver nanoparticles for biomedical uses: a computational study

Zuniga-Bustos, Matias; Galaz-Araya, Constanza; Poblete, Horacio

Article ISI
PHYSICAL CHEMISTRY CHEMICAL PHYSICS  (2025)

Assessment of the Activity of Nitroisoxazole Derivatives against Trypanosoma cruzi

Moncada-Basualto, Mauricio; Saavedra-Olavarria, Jorge; Rivero-Jerez, Paula S.; Rojas, Cristian; Maya, Juan D.; Liempi, Ana; Zuniga-Bustos, Matias; Olea-Azar, Claudio; Lapier, Michel; Perez, Edwin G.; et al.

Article ISI
MOLECULES  (2024)

In Vitro Evaluation of New 5-Nitroindazolin-3-one Derivatives as Promising Agents against Trypanosoma cruzi

Pozo-Martinez, Josue; Aran, Vicente J.; Zuniga-Bustos, Matias; Parra-Magna, Sebastian; Rocha-Valderrama, Esteban; Liempi, Ana; Castillo, Christian; Olea-Azar, Claudio; Moncada-Basualto, Mauricio

Article ISI SCOPUS
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES  (2024)

Thermodynamics of the physisorption of capping agents on silver nanoparticles

Zuniga-Bustos, Matias; Comer, J.; POBLETE-VILCHES, HORACIO

Article ISI SCOPUS
PHYSICAL CHEMISTRY CHEMICAL PHYSICS  (2023)

Nanoengineered Sprayable Therapy for Treating Myocardial Infarction

MUNOZ-FLORES, MARCELO ANDRES; Cimenci, Cagla Eren; Eren Cimenci, Cagla; Goel, Keshav; Comtois-Bona, Maxime; Hossain, Mahir; McTiernan, Christopher D.; Zuniga-Bustos, Matias; Ross, Alex; Truong, Brenda; et al.

Article ISI SCOPUS
ACS Nano  (2022)

Search for Novel Potent Inhibitors of the SARS-CoV-2 Papain-like Enzyme: A Computational Biochemistry Approach

Gallardo, Mauricio; Mulia-Rodriguez, Jorge; Gonzalez-Nilo, Fernando

Article ISI
PHARMACEUTICALS  (2022)

Self-Organization Dynamics of Collagen-like Peptides Crosslinking Is Driven by Rose-Bengal-Mediated Electrostatic Bridges

Salas-Sepulveda, Francisca; Poblete, Horacio

Article ISI
PHARMACEUTICS  (2022)

Stabilization of Carbon Nanotubes and Graphene by Tween-80: Mechanistic from and Simulation Studies

Bisht, Alpna; Zuniga-Bustos, Matias; Prasher, Garima; Gautam, Surbhi; POBLETE-VILCHES, HORACIO; Singh, Raman Preet

Article ISI SCOPUS
LANGMUIR  (2022)

Molecular rotors as reporters for viscosity of solutions of collagen like peptides

McTiernan, Christopher D.; Zuniga-Bustos, Matias; Rosales-Rojas, Roberto; Barrias, Pablo; Griffith, May; POBLETE-VILCHES, HORACIO; Sherin, Peter S.; López-Duarte, Ismael; Kuimova, Marina K.; ALARCON-PANICHINI, EMILIO EXEQUIEL

Article ISI SCOPUS
PHYSICAL CHEMISTRY CHEMICAL PHYSICS  (2021)

In Silico Design of Novel Mutant Anti-MUC1 Aptamers for Targeted Cancer Therapy

Santini B.L.

Article ISI SCOPUS
JOURNAL OF CHEMICAL INFORMATION AND MODELING  (2020)

Mechanism-Based Rational Discovery and In Vitro Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity

Jana, Gonzalo A.; Guzman, Jose L.

Article ISI
JOURNAL OF CHEMICAL INFORMATION AND MODELING  (2020)

Light-Activated Peptide-Based Materials for Sutureless Wound Closure

McTiernan C.D.; Cortes D.C.; Amrani, S; Rosales-Rojas R.; Sedlakova V.

Article ISI SCOPUS
ACS APPLIED MATERIALS & INTERFACES  (2019)

Modulation of glucan-enzyme interactions by domain V in GTF-SI from Streptococcus mutans

Jana, GA; Jiménez, VA

Article ISI SCOPUS
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS  (2019)

Molecular modeling simulation studies reveal new potential inhibitors against HPV E6 protein

Ricci-Lopez, J; Vidal-Limon, A; Zunniga, M; Jiménez, VA; Alderete, JB; Brizuela, CA; Aguila, S

Article ISI SCOPUS
PLOS ONE  (2019)

Molecular modeling study on the differential microtubule‐stabilizing effect in singly‐ and doubly‐bonded complexes with peloruside A and paclitaxel

Alderete, Joel B.

Article SCOPUS
Proteins: Structure, Function and Bioinformatics  (2019)

Nanoparticle Concentration vs Surface Area in the Interaction of Thiol-Containing Molecules: Toward a Rational Nanoarchitectural Design of Hybrid Materials

Zuñiga-Bustos M.; Lazurko C.

Article ISI SCOPUS
ACS APPLIED MATERIALS & INTERFACES  (2019)

Effect of pH on Eosin Y/PAMAM interactions studied from absorption spectroscopy and molecular dynamics simulations

Barraza, LF; Alderete, JB; Arbeloa, EM; Jiménez, VA

Article ISI SCOPUS
JOURNAL OF LUMINESCENCE  (2018)

Modulation of lateral and longitudinal interdimeric interactions in microtubule models by Laulimalide and Peloruside A association: A molecular modeling approach on the mechanism of microtubule stabilizing agents

Alderete, JB; Jana, GA; Jiménez, VA

Article ISI SCOPUS
CHEMICAL BIOLOGY & DRUG DESIGN  (2018)

Structural insight into the role of Gln293Met mutation on the Peloruside A/Laulimalide association with alpha beta-tubulin from molecular dynamics simulations, binding free energy calculations and weak interactions analysis



Article ISI SCOPUS
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN  (2017)

Molecular Determinants of Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P-2) Binding to Transient Receptor Potential V1 (TRPV1) Channels

Poblete, H.; Oyarzun, I; Olivero P.; Comer, J.; Zúñiga M; Sepúlveda R.V.; Baez-Nieto, D; Gonzalez-Nilo, F; Latorre, R

Article ISI SCOPUS
JOURNAL OF BIOLOGICAL CHEMISTRY  (2015)

Optimal graph-based and Simplified Molecular Input Line Entry System-based descriptors for quantitative structure-activity relationship analysis of arylalkylaminoalcohols, arylalkenylamines, and arylalkylamines as sigma(1) receptor ligands

Quesada-Romero, L; Mena-Ulecia, K; Zúñiga M; De-La-Torre, P; Rossi, D; Tiznado, W; Collina, S; Caballero, J

Article ISI SCOPUS
JOURNAL OF CHEMOMETRICS  (2015)

Computational study of the complexation of metals ions with poly(amidoamine) PAMAM GO dendrimers

Camarada, MB; Zúñiga M; Alzate-Morales, J; Santos, LS

Article ISI SCOPUS
CHEMICAL PHYSICS LETTERS  (2014)

Functional Analysis of the Brassica napus L. Phytoene Synthase (PSY) Gene Family

Lopez-Emparan A.; Quezada-Martinez D.; Zuniga-Bustos M.; Cifuentes, V; Iniguez-Luy, F; Federico M.L.

Article ISI SCOPUS
PLOS ONE  (2014)

In situ and in silico evaluation of amine- and folate-terminated dendrimers as nanocarriers of anesthetics

Carrasco-Sanchez, V; Vergara-Jaque, A; Zúñiga M; Comer, J.; John A.; Nachtigall, FM; Valdés, O; Duran-Lara, EF; Sandoval, C.; Santos, LS

Article ISI SCOPUS
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY  (2014)

1
José Pérez

Associate Professor

Biologia

Universidad Andres Bello

Santiago, Chile

1
Víctor Cifuentes

Prof. Titular

Departamento de Ciencias Ecológicas

FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE.

Santiago, Chile

5
Joel Alderete

Full Professor

Universidad de Talca

Talca, Chile

1
ramon latorre

Profesor

Instituto de Neurociencia

Universidad de Valparaíso

5, Chile

2
LEONARDO SILVA

PROFESOR TITULAR

UNIVERSIDAD DE TALCA

TALCA, Chile

1
EDWIN PÉREZ

Profesor Asociado

Departamento de Química Orgánica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Francisco Valenzuela

Profesor Asociado

INSTITUTO DE MATEMÁTICAS - PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO

Valparaíso, Chile

1
Luisa Quesada

Docente e investigadora

Nutrición y Dietética

Universidad San Sebastián

Valdivia, Chile

1
William Tiznado

Full professor

Chemical Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

1
JOSE GUZMAN

Full professor

Fisiología

Universidad de Concepción

Concepcion, Chile

1
Julio Caballero

Full Professor

Departamento de Bioinformática

Universidad de Talca

Talca, Chile

8
Veronica Jimenez

Assistant Professor

Chemistry

Universidad Andres Bello

Talcahuano, Chile

4
Gonzalo Jaña

Profesor Asociado

Ciencias Químicas

Universidad Andres Bello

Concepción, Chile

1
Oscar Valdés

Académico

Universidad Católica del Maule

Talca, Chile

1
Luis Barraza

ACADEMICO-INVESTIGADOR

DEPARTAMENTO DE CIENCIAS BIOLOGICAS Y QUIMICAS

Universidad San Sebastián

Valdivia, Chile

1
Michel Lapier

Académico

Química y Farmacia

Universidad de Valparaíso

Valparaíso, Chile

1
Ricardo Zamora

Researcher Assistant

Universidad de Talca

Talca, Chile

1
Claudia Sandoval

Secretaria Académica Facultad de Ingeniería

Instituto de Ciencias Químicas Aplicadas

Universidad Autónoma de Chile

Santiago, Chile

1
Horacio Poblete

Profesor Conferenciante

Universidad de Talca

Talca, Chile

1
Fabiane Manke

Académico Docente Investigador

Universidad Autónoma de Chile

Talca, Chile

1
John Amalraj

Associate Professor

Instituto de Quimica de Recursos Naturales

Universidad de Talca

Talca, Chile

1
Mauricio Moncada

1
osvaldo yañez

Académico Investigador

Facultad de Ingeniería y Negocios

Universidad de Las Américas

Santiago, Chile

24
Matías Zúñiga

Postdoctorado

Centro de Bioinformática y Simulación Molecular

Universidad de Talca

TALCA, Chile

1
Fernanda Mendoza

Docente e Investigadora

Ciencias Químicas

Universidad Andrés Bello

Talcahuano, Chile

1
Romina Sepúlveda

Profesor Investigador

Facultad de Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

3
Constanza Galaz

Postdoctorado

Universidad de Concepción

Concepción, Chile